Publications   

This list of publications includes those publications of the founding members of this website that are relevant to aromatic amino acid metabolism. Authorship by R. Jensen, J. Song, and C. Bonner highlighted with black, red, and blue lettering, respectively. Where possible, HTML and pdf files are provided for download. In some cases, notes, clarifications, text corrections, figure corrections or improvements are also provided.

  1. Champney, W. S., and R. A. Jensen. 1969. D-Tyrosine as a metabolic inhibitor of Bacillus subtilis. J. Bacteriol 98:205-214. [ABSTRACT][PDF]

  2. Champney, W. S., and R. A. Jensen. 1970. Metabolic influences on tyrosine excretion in Bacillus subtilis. J Bacteriol 104:351-359. [ABSTRACT][PDF]

  3. Champney, W. S., and R. A. Jensen. 1970. The enzymology of prephenate dehydrogenase in Bacillus subtilis. J Biol Chem 245:3763-3770. [ABSTRACT][PDF]

  4. Champney, W. S., and R. A. Jensen. 1970. Molecular events in the growth inhibition of Bacillus subtilis by D-tyrosine. J Bacteriol 104:107-116. [ABSTRACT][PDF]

  5. Jensen, R. A., S. L. Stenmark, and W. S. Champney. 1972. Molecular basis for the differential anti-metabolite action of D-tyrosine in strains 23 and 168 of Bacillus subtilis. Arch Microbiol 87:173-180. [PDF]

  6. Calhoun, D. H., D. L. Pierson, and R. A. Jensen. 1973. Channel-shuttle mechanism for the regulation of phenylalanine and tyrosine synthesis at a metabolic branch point in Pseudomonas aeruginosa. J Bacteriol 113:241-251. [ABSTRACT][PDF]

  7. D'Ambrosio, S. M., G. I. Glover, S. O. Nelson, and R. A. Jensen. 1973. Specificity of the tyrosine-phenylalanine transport system in Bacillus subtilis. J Bacteriol 115:673-681. [ABSTRACT][PDF]

  8. Stenmark, S. L., D. L. Pierson, F. I. Glover, and R. A. Jensen. 1974. Blue-green bacteria synthesize L-tyrosine by the pretyrosine pathway. Nature 247:290-292.

  9. D'Ambrosio, S. M., F. I. Glover, and R. A. Jensen. 1975. Kinetics of affinity labeling the L-tyrosine/L-phenylalanine transport system in Bacillus subtilis. Arch Biochem Biophys Arch Biochem Biophys:754-760. [PDF]

  10. Glover, G. I., S. M. D'Ambrosio, and R. A. Jensen. 1975. Versatile properties of a nonsaturable, homogeneous transport system in Bacillus subtilis:  genetic, kinetic and affinity-labeling studies. Proc Natl Acad Sci USA 72:814-818. [ABSTRACT][PDF]

  11. Jensen, R. A., and D. L. Pierson. 1975. Evolutionary implications of different types of microbial enzymology for L-tyrosine biosynthesis. Nature 254:667-671.

  12. Jensen, R. A., and S. L. Stenmark. 1975. The ancient origin of a second microbial pathway of L-tyrosine biosynthesis in prokaryotes. J Mol Evol 4:249-259. [PDF]

  13. Stenmark-Cox, S. L., and R. A. Jensen. 1975. Prephenate dehydrogenase from Pseudomonas aeruginosa is a regulated component of the channel-shuttle mechanism controlling tyrosine-phenylalanine synthesis. Arch Biochem Biophys 167:540-546.

  14. Jensen, R. A., L. O. Zamir, M. St. Pierre, N. Patel, and D. L. Pierson. 1977. Isolation and preparation of pretyrosine, accumulated as  a dead-end metabolite by Neurospora crassa. J Bacteriol 132:896-903. [ABSTRACT][PDF]

  15. Patel, N., D. L. Pierson, and R. A. Jensen. 1977. Dual enzymatic routes to L-tyrosine and L-phenylalanine via pretyrosine in Pseudomonas aeruginosa. J Biol Chem 252:5839-5846. [PDF]

  16. Patel, N., S. Stenmark-Cox, and R. A. Jensen. 1978. Enzymological basis of reluctant auxotrophy for phenylalanine and tyrosine in Pseudomonas aeruginosa. J Biol Chem 253:2972-2978. [PDF]

  17. Fazel, A. M., and R. A. Jensen. 1979. Obligatory biosynthesis of L-tyrosine via the pretyrosine branchlet in coryneform bacteria. J Bacteriol 138:805-815. [ABSTRACT][PDF]

  18. Fazel, A. M., and R. A. Jensen. 1979. Aromatic aminotransferases in coryneform bacteria. J Bacteriol 140:580-587. [ABSTRACT][PDF]

  19. Rubin, J. L., and R. A. Jensen. 1979. The enzymology of L-tyrosine biosynthesis in mung bean (Vigna radiata [L.] Wilczek) Plant Physiol 64:727-734. [ABSTRACT][PDF]

  20. Byng, G. S., R. J. Whitaker, R. L. Gherna, and R. A. Jensen. 1980. Variable enzymological patterning in tyrosine biosynthesis as a means of determining natural relatedness among the Pseudomonadaceae. J Bacteriol 144:247-257. [ABSTRACT][PDF]

  21. Fazel, A. M., J. R. Bowen, and R. A. Jensen. 1980. Arogenate (pretyrosine) is an obligatory intermediate of L-tyrosine biosynthesis:  confirmation in a microbial mutant. Proc Natl Acad Sci USA  (Biochemistry) 77:1270-1273. ABSTRACT][PDF]

  22. Zamir, L. O., R. A. Jensen, B. Arison, A. Douglas, G. Albers-Schonberg, and J. R. Bowen. 1980. Structure of arogenate (pretyrosine), an amino acid intermediate of aromatic biosynthesis. J Am Chem Soc 102:4499-4504.

  23. Byng, G. S., R. J. Whitaker, C. Flick, and R. A. Jensen. 1981. Enzymology of L-tyrosine biosynthesis in corn (Zea mays). Phytochemistry 20:1289-1292.

  24. Byng, G. S., R. J. Whitaker, C. L. Shapiro, and R. A. Jensen. 1981. The aromatic amino acid pathway branches at L-arogenate in Euglena gracilis. Mol Cell Biol 1:426-438. [ABSTRACT][PDF]

  25. Flick, C. E., R. A. Jensen, and D. A. Evans. 1981. Isolation, protoplast culture, and plant regeneration of PFP-resistant variants of N. tabacum Su/Su. . Z Pflanzenphysiol 103:239-245.

  26. Jensen, R. A., and D. H. Calhoun. 1981. Intracellular roles of microbial aminotransferases: overlap enzymes across different biochemical pathways. Crit Rev Microbiol 8:229-266.

  27. Gaines, C. G., G. S. Byng, R. J. Whitaker, and R. A. Jensen. 1982. L-Tyrosine regulation and biosynthesis via arogenate dehydrogenase in suspension-cultured cells of Nicotiana silvestris (Speg. et Comes).  . Planta 156::233-240.

  28. Gaines, C. G., G. S. Byng, R. J. Whitaker, and R. A. Jensen. 1982. L-Tyrosine regulation and biosynthesis via arogenate dehydrogenase in suspension-cultured cells of Nicotiana silvestris (Speg. et Comes). Planta 156:233-240.

  29. Hall, G. C., M. B. Flick, R. L. Gherna, and R. A. Jensen. 1982. Biochemical diversity for biosynthesis of aromatic amino acids among the cyanobacteria. J. Bacteriol 149:65-78. [ABSTRACT][PDF]

  30. Whitaker, R. J., C. G. Gaines, and R. A. Jensen. 1982. A multi-specific quintet of aromatic aminotransferases that overlap different biochemical pathways in Pseudomonas aeruginosa. J Biol Chem 257:13550-13556. [ABSTRACT][PDF]

  31. Bonner, C. A., and R. A. Jensen. 1985. Novel features of prephenate aminotransferase from cell cultures of Nicotiana silvestris. Arch Biochem Biophys 238:237-246. [ABSTRACT][PDF]

  32. Byng, G. S., A. Berry, and R. A. Jensen. 1985. Evolutionary implications of features of aromatic amino acid biosynthesis in the genus Acinetobacter. Arch Microbiol 143:122-129. [ABSTRACT][PDF]

  33. Whitaker, R. L., A. Berry, G. S. Byng, M. J. Fiske, and R. A. Jensen. 1985. Clues from Xanthomonas campestris about the evolution of aromatic biosynthesis and its regulation. J Mol Evol 21:139-149. [ABSTRACT][Correction]

  34. Ahmad, S., and R. A. Jensen. 1986. The evolutionary history of two bifunctional proteins that emerged in the purple bacteria. Trends Biochem Sci 11:108-112.

  35. Jensen, R. A. 1986. Tyrosine and phenylalanine biosynthesis:  relationship between alternative pathways, regulation and subcellular location   ISBN 0-306-42283-2. Rec Adv Phytochem 20:57-82.

  36. Ahmad, S., and R. A. Jensen. 1987. Evolution of the biochemical pathway for aromatic amino acid biosynthesis in Serpens flexibilis in relationship to its phylogenetic position. Arch Microbiol 147:8-12.

  37. Ahmad, S., and R. A. Jensen. 1987. The prephenate dehydrogenase component of the bifunctional T-protein in enteric bacteria can utilize L-arogenate. FEBS Lett 216:133-139. [ABSTRACT][PDF]

  38. Berry, A., R. A. Jensen, and A. T. Hendry. 1987. Enzymatic arrangement and allosteric regulation of the aromatic amino acid pathway in Neisseria gonorrhoeae. Arch Microbiol 149:87-94. [ABSTRACT][PDF]

  39. Berry, A., A. Liss, and R. A. Jensen. 1987. Enzymological features of aromatic amino acid biosynthesis reflect the phylogeny of mycoplasmas. J Gen Microbiol 133:2147-2154. [ABSTRACT]

  40. Bonner, C. A., and R. A. Jensen. 1987. In: METHODS IN ENZYMOLOGY - Prephenate aminotransferase.  142:479-487.

  41. Bonner, C. A., and R. A. Jensen. 1987. Arogenate dehydrogenase. In:  METHODS IN ENZYMOLOGY - Chapter 58 142:488-494.

  42. Bonner, C. A., and R. A. Jensen. 1987. A selective assay for prephenate aminotransferase activity in suspension-cultured cells of Nicotiana silvestris cells. Planta 172:417-423. [ABSTRACT]

  43. Fischer, R. S., and R. A. Jensen. 1987. Prephenate dehydrogenase (monofunctional). In:  METHODS IN ENZYMOLOGY -Chapter 60 142:503-507.

  44. Jensen, R. A., and R. S. Fischer. 1987. The postprephenate biochemical pathways to phenylalanine and tyrosine:  An overview, p. 472-478. In S. P. SP Colowick and N. O. Kaplan (ed.), Metabolism of aromatic amino acids and amines - In:  METHODS IN ENZYMOLOGY-Chapter 56, vol. 142. Academic Press, Inc. , Orlando, FL.

  45. Ahmad, S., and R. A. Jensen. 1988. New prospects for deducing the evolutionary history of metabolic pathways in prokaryotes:  Aromatic biosynthesis as a case-in-point. Origins of Life & Evol Biosphere 18:41-57. [ABSTRACT][PDF]

  46. Ahmad, S., and R. A. Jensen. 1988. The phylogenetic origin of the bifunctional tyrosine-pathway protein in the enteric lineage of bacteria. Mol Biol Evol 5:282-297. [ABSTRACT][PDF]

  47. Ahmad, S., and R. A. Jensen. 1988. The stable evolutionary fixation of a bifunctional tyrosine-pathway protein in enteric bacteria. FEMS Microbiol Lett 52:109-116.

  48. Ahmad, S., W. G. Weisburg, and R. A. Jensen. 1990. Evolution of aromatic amino acid biosynthesis and application to the fine-tuned phylogenetic positioning of enteric bacteria. J Bacteriol 172:1051-1061. [ABSTRACT][PDF]

  49. Bonner, C. A., R. S. Fischer, S. Ahmad, and R. A. Jensen. 1990. Remnants of an ancient pathway to L-phenylalanine and L-tyrosine in enteric bacteria:  evolutionary implications and biotechnological impact. Appl Environ Microbiol 56:3741-3747. [ABSTRACT][PDF]

  50. Hendry, A. T., R. K. Bhatnagar, K. T. Shanmugam, and R. A. Jensen. 1990. Exploitation of the broad specificity of the membrane-bound isozyme of lactate dehydrogenase for direct selection of null mutants in Neisseria gonorrhoeae. J Gen Microbiol 136:45-50.

  51. Jensen, R. A., and S. Ahmad. 1990. Nested gene fusions as markers of phylogenetic branchpoints in prokaryotes. Trends Ecol Evol 5:219-224.

  52. Xia, T., and R. A. Jensen. 1990. A single cyclohexadienyl dehydrogenase specifies the prephenate dehydrogenase and arogenate dehydrogenase components of the dual pathways to L-tyrosine in Pseudomonas aeruginosa. J Biol Chem 265:20033-20036. [ABSTRACT][PDF]

  53. Hrazdina, G., and R. A. Jensen. 1992. Spatial organization of enzymes in plant metabolic pathways. Annu Rev Plant Physiol  Plant Mol Biol 43:241-267. [PDF]

  54. Jensen, R. A. 1992. An emerging outline of the evolutionary history of aromatic amino acid biosynthesis, p. 205-236. In R. P. Mortlock (ed.), The Evolution of Metabolic Function, vol. Chapter 9. CRC Press, Inc, Boca Raton, FL.

  55. Xia, T., G. Zhao, R. Fischer, and R. A. Jensen. 1992. A monofunctional prephenate dehydrogenase created by cleavage of the 5' 109-bp of the tyrA gene from Erwinia herbicola. J Gen Microbiol 138:1309-1316. [ABSTRACT]

  56. Fischer, B., C. A. Bonner, D. R. Boone, and R. A. Jensen. 1993. Clues from a halophilic methanogen about aromatic amino acid biosynthesis in archaebacteria. Arch Microbiol 160:440-446. [ABSTRACT][PDF]

  57. Fischer, R. S., C. A. Bonner, M. E. Theodorou, W. C. Plaxton, G. Hrazdina, and R. A. Jensen. 1993. Response of aromatic pathway enzymes of plant suspension cells to phosphate limitation. Bioorg & Med Chem Lett 7:1415-1420.

  58. Xia, T., G. Zhao, and R. A. Jensen. 1993. The pheA/tyrA/aroF region from Erwinia herbicola:  An emerging comparative basis for analysis of gene organization and regulation in enteric bacteria. J Mol Evol 36:107-120. [ABSTRACT]

  59. Zhao, G., T. Xia, L. O. Ingram, and R. A. Jensen. 1993. An allosterically insensitive class of cyclohexadienyl dehydrogenase from Zymomonas mobilis. Eur J Biochem 212:157-165. [ABSTRACT]

  60. Subramaniam, P. S., R. K. Bhatnagar, A. Hooper, and R. A. Jensen. 1994. The dynamic progression of evolved character states for aromatic amino acid biosynthesis in gram-negative bacteria. Microbiology 140:3431-3440. [ABSTRACT]

  61. Abou-Zeid, A., G. J. W. Euverink, G. I. Hessels, and R. A. Jensen. 1995. Biosynthesis of L-phenylalanine and L-tyrosine in the actinomycete Amycolatopsis methanolica. Appl & Environ Microbiol 61:1298-1302. [ABSTRACT][PDF]

  62. Bonner, C. A., R. S. Fischer, R. R. Schmidt, P. W. Miller, and R. A. Jensen. 1995. Distinctive enzymes of aromatic amino acid biosynthesis that are highly conserved in land plants are also present in the chlorophyte alga Chlorella sorokiniana. Plant and Cell Physiol 36:1013-1022. [ABSTRACT]

  63. Xie, G., C. A. Bonner, and R. A. Jensen. 2000. Cyclohexadienyl dehydrogenase from Pseudomonas stutzeri exemplifies a widespread type of tyrosine-pathway dehydrogenase in the TyrA protein family. Comp Biochem Physiol C Toxicol Pharmacol 125:65-83. [HTML]

  64. Bonner, C. A., R. A. Jensen, J. E. Gander, and N. O. Keyhani. 2004. A core catalytic domain of the TyrA protein family: arogenate dehydrogenase from Synechocystis. Biochem J 382:279-291. [HTML][PDF]

  65. Song, J., C. A. Bonner, M. Wolinsky, and R. A. Jensen. 2005. The TyrA family of aromatic-pathway dehydrogenases in phylogenetic context    BMC Biology  3:13. [HTML][PDF][Table of Contents][Replacement for Fig. 2]