┌─ Escherichia coli CFT073   
                     ┌┴─ Escherichia coli 83972 (3)  
                    ┌┴─ Escherichia coli FVEC1302 (3)  
                   ┌┴─ Escherichia coli ED1a (1)  
                  ┌┴─ Escherichia coli 53638 (1)  
                 ┌┴┬─ Escherichia coli 1044A (28)  
                 │ └┬─ Escherichia coli F11 (1) [2] 
                ┌┤  └─ Escherichia coli UM146 (2)  
               ┌┤└─ Escherichia coli E110019 (3)  
               │└┬─ fig|1040638.4.peg.2516 O104:H4 str. LB226692 (9)  
              ┌┤ └─ Escherichia coli 042 (3)  
              │└┬─ Escherichia coli 2362-75 (9)  
             ┌┤ └─ Escherichia coli 1044A (18)  
             │└┬─ Escherichia coli H299   
             │ └┬─ Escherichia coli B088   
            ┌┤  └┬─ Escherichia coli CFT073   
            ││   └┬─ Escherichia coli 83972 (4)  
            ││    └─ Escherichia coli MS 185-1   
           ┌┤└┬─ Escherichia coli E110019 (1)  
           ││ └┬─ Escherichia coli ED1a (2)  
         ┌─┤│  └─ Escherichia coli EC4100B   
         │ │└─ Escherichia coli O157:H7 str. EC869   
         │ └┬─ Escherichia coli MS 175-1   
┌────────┤  └┬─ Escherichia coli 042 (9)  
│        │   └┬─ fig|1040638.4.peg.681 O104:H4 str. LB226692   
│        │    └─ Escherichia coli 042 (17)  
│        └─ Escherichia coli MS 182-1   
│         ┌─ Escherichia coli (1-107/115) B185   
│        ┌┴─ Escherichia coli (1-107/115) E110019 (1)  
│       ┌┴─ fig|1040638.4.peg.115 O104:H4 (1-107/115) str. LB226692 (65)  
│      ┌┴─ Escherichia coli (1-107/115) H299 (2)  
│     ┌┴┬─ Escherichia coli (1-107/115) 536 (2)  
│     │ └┬─ Escherichia coli (1-107/115) 101-1   
┤    ┌┤  └┬─ Escherichia coli (1-107/115) SE11   
│    ││   └─ Escherichia coli (1-107/115) E110019 (2)  
│   ┌┤└─ Escherichia coli (1-107/115) 53638 (1)  
│  ┌┤└─ Escherichia coli (1-107/115) 53638 (1)  
│ ┌┤└─ Escherichia coli (1-107/115) B171 (9)  
│┌┤└─ Escherichia coli B171 (1)  
││└──────┬─ Escherichia coli (1-107/115) TA280   
││       └┬─ Escherichia coli (1-107/115) EC4100B (5)  
││        └┬─ Escherichia coli (1-97/116) 2362-75   
││         └┬─ Escherichia coli (1-107/115) 1212A   
└┤          └─ Escherichia coli (1-107/115) 1044A (33)  
 │                                                              ┌─ Escherichia coli (7-103/126) O26:H11 str. 11368 (26)  
 │                                                             ┌┴─ Escherichia coli (7-103/113) O111:H- str. 11128   
 │                                                           ┌─┴─ Escherichia coli (7-103/126) KO11 (3)  
 │┌──────────────────────────────────────────────────────────┴──────┬─ Escherichia coli (15-103/130) CFT073  [2] 
 ││                                                                 └─ Escherichia coli (146-257/284) MS 196-1   
 └┤ ┌───── Escherichia coli (1-107/115) TA271   
  │ │          ┌─ Escherichia coli MS 21-1   
  │ │         ┌┴─ Escherichia coli O26:H11 str. 11368   
  └─┤        ┌┴─ Escherichia coli O55:H7 str. CB9615   
    │       ┌┴─ fig|1040638.4.peg.209 O104:H4 str. LB226692 (15)  
    │      ┌┴─ fig|6666666.5357.peg.4487 TY-2482 strain (38)  
    │      │ ┌─ fig|1040638.4.peg.3560 O104:H4 str. LB226692 (8)  
    └──────┤┌┴─ Escherichia coli MS 115-1   
           ││┌─ Escherichia coli O157:H7 str. EC4196   
           └┤│  ┌─ Escherichia coli 1125A   
            ││ ┌┴─ Escherichia coli 536A   
            └┤┌┴─ Escherichia coli 042 (1)  
             ││  ┌─ Escherichia coli H299   
             ││ ┌┴─ Escherichia coli E110019 (1)  
             └┤┌┴┬─ Escherichia coli ED1a (1)  
              ││ └─ Escherichia coli O157:H7 (1)  
              ││ ┌─ Escherichia coli MS 116-1 (1)  
              └┤┌┴─ Escherichia coli MS 78-1   
               ││   ┌─ Escherichia coli 1125A   
               ││  ┌┴─ Escherichia coli B171 (1)  
               └┤ ┌┴─ fig|6666666.5357.peg.4544 TY-2482 (75-189/189) strain   
                │┌┴┬─ Escherichia coli 1212A   
                ││ └┬─ Escherichia coli (2-98/98) B171 (1)  
                └┤  └─ Escherichia coli O157:H7 EDL933 (3)  
                 │┌─ Escherichia coli O157:H7 EDL933   
                 └┤┌─ Escherichia coli (72-186/186) O157:H7 EDL933 (302)  
                  └┤ ┌─ Escherichia coli 1212A   
                   └┬┴─ Escherichia coli (6-105/105) 2362-75   
                    └┬─ Escherichia coli O157:H7 str. EC869   
                     └┬─ Escherichia coli MS 21-1   
                      └┬─ Escherichia coli ED1a (1)  
                       └─ Escherichia coli 042 (2)  
  

  
unknown in ISEc8
 (21)
  
orf, conserved hypothetical protein
 (15)
  
hypothetical protein
 (13)
  
putative IS encoded protein encoded within prophage CP-933O
 (6)
  
Insertion Sequence Associated
 (4)
  
ISPsy5, Orf1
 (4)
  
IS66 family element, orf2
 (3)
  
orf; Unknown function (Insertion Sequence Associated)
 (3)
  
Orf50 protein
 (3)
  
ISSfl4 ORF2
 (1)
  
unknown protein encoded in ISEc8
 (1)
  
 Others 
(7)