fig|1040638.4.peg.693
Escherichia coli O104:H4 str. LB226692
ML
RPE
KG
HEFML
NL
L
F
H
LK
M
N
G
RQ
F
CWL
I
V
G
S
G
SP
E
L
R
E
H
L
Q
Y
Q
I
D
SM
GM
H
D
D
V
F
IAD
NV
F
P
A
A
P
V
YR
V
---
A
SLVV
LPS
------
EN
E
S
FGMV
L
A
EA
S
A
F
SV
PVV
A
-
T
QI
G
GIPE
VIQ
N
N
Q
T
G
T
L
L
P
A
GN
KH
A
W
MC
A
L
ND
F
FN
-
D
P
G
RF
YQ
M
ARL
A
KQDI
E
E
R
F
DIN
K
TA
LK
I
L
T
L
AK
QK
fig|6666666.5357.peg.276
Escherichia coli TY-2482 (193-362/362)
ML
RPE
KG
HEFML
NL
L
F
H
LK
M
N
G
RQ
F
CWL
I
V
G
S
G
SP
E
L
R
E
H
L
Q
Y
Q
I
D
SM
GM
H
D
D
V
F
IAD
NV
F
P
A
A
P
V
YR
V
---
A
SLVV
LPS
------
EN
E
S
FGMV
L
A
EA
S
A
F
SV
PVV
A
-
T
QI
G
GIPE
VIQ
N
N
Q
T
G
T
L
L
P
A
GN
KH
A
W
MC
A
L
ND
F
FN
-
D
P
G
RF
YQ
M
ARL
A
KQDI
E
E
R
F
DIN
K
TA
LK
I
L
T
L
AK
QK
fig|358709.5.peg.2368
Escherichia coli 101-1 (193-362/362)
ML
RPE
KG
HEFML
NL
L
F
H
LK
M
N
G
RQ
F
CWL
I
V
G
S
G
SP
E
L
R
E
H
L
Q
Y
Q
I
D
SM
GM
H
D
D
V
F
IAD
NV
F
P
A
A
P
V
YR
V
---
A
SLVV
LPS
------
EN
E
S
FGMV
L
A
EA
S
A
F
SV
PVV
A
-
T
QI
G
GIPE
VIQ
N
N
Q
T
G
T
L
L
P
A
GN
KH
A
W
MC
A
L
ND
F
FN
-
D
P
G
RF
YQ
M
ARL
A
KQDI
E
E
R
F
DIN
K
TA
LK
I
L
T
L
AK
QK
fig|585055.6.peg.4954
Escherichia coli 55989 (193-362/362)
ML
RPE
KG
HEFML
NL
L
F
H
LK
M
N
G
RQ
F
CWL
I
V
G
S
G
SP
E
L
R
E
H
L
Q
Y
Q
I
D
SM
GM
H
D
D
V
F
IAD
NV
F
P
A
A
P
V
YR
V
---
A
SLVV
LPS
------
EN
E
S
FGMV
L
A
EA
S
A
F
SV
PVV
A
-
T
QI
G
GIPE
VIQ
N
N
Q
T
G
T
L
L
P
A
GN
KH
A
W
MC
A
L
ND
F
FN
-
D
P
G
RF
YQ
M
ARL
A
KQDI
E
E
R
F
DIN
K
TA
LK
I
L
T
L
AK
QK
fig|585055.8.peg.4960
Escherichia coli 55989 (193-362/362)
ML
RPE
KG
HEFML
NL
L
F
H
LK
M
N
G
RQ
F
CWL
I
V
G
S
G
SP
E
L
R
E
H
L
Q
Y
Q
I
D
SM
GM
H
D
D
V
F
IAD
NV
F
P
A
A
P
V
YR
V
---
A
SLVV
LPS
------
EN
E
S
FGMV
L
A
EA
S
A
F
SV
PVV
A
-
T
QI
G
GIPE
VIQ
N
N
Q
T
G
T
L
L
P
A
GN
KH
A
W
MC
A
L
ND
F
FN
-
D
P
G
RF
YQ
M
ARL
A
KQDI
E
E
R
F
DIN
K
TA
LK
I
L
T
L
AK
QK
fig|331111.12.peg.307
Escherichia coli E24377A (193-362/362)
ML
RPE
KG
HEFML
NL
L
F
H
LK
M
N
G
RQ
F
CWL
I
V
G
S
G
SP
E
L
R
E
H
L
Q
Y
Q
I
D
SM
GM
H
D
D
V
F
IAD
NI
F
P
A
A
P
V
YR
V
---
A
SLVV
LPS
------
EN
E
S
FGMV
L
A
EA
S
A
F
SV
PVV
A
-
T
QI
G
GIPE
VIQ
N
N
Q
T
G
T
L
L
P
A
GN
KH
A
W
MC
A
L
ND
F
FN
-
D
P
G
RF
YQ
M
ARL
A
KQDI
E
E
R
F
DIN
K
TA
LK
I
L
T
L
AK
QK
fig|344601.3.peg.856
Escherichia coli B171 (193-362/362)
ML
RPE
KG
HEFML
NL
L
F
H
LK
M
N
G
RQ
F
CWL
I
V
G
A
G
SP
E
L
R
E
H
L
Q
Y
Q
I
D
SM
GM
H
D
D
V
F
IAD
NV
F
P
A
A
P
V
YR
V
---
A
SLVV
LPS
------
EN
E
S
FGMV
L
A
EA
S
A
F
SV
PVV
A
-
T
QI
G
GIPE
VIQ
N
N
Q
T
G
T
L
L
P
A
GN
KH
A
W
MC
A
L
ND
F
FN
-
D
P
G
RF
YQ
M
ARL
A
KQDI
E
E
R
F
DIN
K
TA
LK
I
L
T
L
AK
QK
fig|344601.5.peg.902
Escherichia coli B171 (193-362/362)
ML
RPE
KG
HEFML
NL
L
F
H
LK
M
N
G
RQ
F
CWL
I
V
G
A
G
SP
E
L
R
E
H
L
Q
Y
Q
I
D
SM
GM
H
D
D
V
F
IAD
NV
F
P
A
A
P
V
YR
V
---
A
SLVV
LPS
------
EN
E
S
FGMV
L
A
EA
S
A
F
SV
PVV
A
-
T
QI
G
GIPE
VIQ
N
N
Q
T
G
T
L
L
P
A
GN
KH
A
W
MC
A
L
ND
F
FN
-
D
P
G
RF
YQ
M
ARL
A
KQDI
E
E
R
F
DIN
K
TA
LK
I
L
T
L
AK
QK
fig|585397.7.peg.5110
Escherichia coli ED1a (193-362/362)
ML
RPE
KG
HEFML
NL
L
F
H
LK
M
N
G
RQ
F
CWL
I
V
G
S
G
SP
E
L
R
E
H
L
Q
Y
Q
I
D
SM
GM
H
D
D
V
F
IAD
NV
F
P
A
A
P
V
YR
V
---
A
SLVV
LPS
------
EN
E
S
FGMV
L
A
EA
S
A
F
SV
PVV
A
-
T
QI
G
GIPE
VIQ
N
N
Q
T
G
T
L
L
P
A
GN
KH
A
W
MC
A
L
NN
F
FN
-
D
P
G
RF
YQ
M
ARL
A
KQDI
E
E
R
F
DIN
K
TA
LK
I
L
T
L
AK
QK
fig|585397.9.peg.5112
Escherichia coli ED1a (193-362/362)
ML
RPE
KG
HEFML
NL
L
F
H
LK
M
N
G
RQ
F
CWL
I
V
G
S
G
SP
E
L
R
E
H
L
Q
Y
Q
I
D
SM
GM
H
D
D
V
F
IAD
NV
F
P
A
A
P
V
YR
V
---
A
SLVV
LPS
------
EN
E
S
FGMV
L
A
EA
S
A
F
SV
PVV
A
-
T
QI
G
GIPE
VIQ
N
N
Q
T
G
T
L
L
P
A
GN
KH
A
W
MC
A
L
NN
F
FN
-
D
P
G
RF
YQ
M
ARL
A
KQDI
E
E
R
F
DIN
K
TA
LK
I
L
T
L
AK
QK
fig|585057.4.peg.4904
Escherichia coli IAI39 (193-362/362)
ML
RPE
KG
HEFML
NL
L
F
H
LK
M
N
G
RQ
F
CWL
I
V
G
S
G
SP
E
L
R
E
H
L
Q
Y
Q
I
D
SM
GM
H
D
D
V
F
IAD
NV
F
P
A
A
P
V
YR
V
---
A
SLVV
LPS
------
EN
E
S
FGMV
L
A
EA
S
A
F
SV
PVV
A
-
T
QI
G
GIPE
VIQ
N
N
Q
T
G
T
L
L
P
A
GN
KH
A
W
MC
A
L
NN
F
FN
-
D
P
G
RF
YQ
M
ARL
A
KQDI
E
E
R
F
DIN
K
TA
LK
I
L
T
L
AK
QK
fig|585057.6.peg.4913
Escherichia coli IAI39 (193-362/362)
ML
RPE
KG
HEFML
NL
L
F
H
LK
M
N
G
RQ
F
CWL
I
V
G
S
G
SP
E
L
R
E
H
L
Q
Y
Q
I
D
SM
GM
H
D
D
V
F
IAD
NV
F
P
A
A
P
V
YR
V
---
A
SLVV
LPS
------
EN
E
S
FGMV
L
A
EA
S
A
F
SV
PVV
A
-
T
QI
G
GIPE
VIQ
N
N
Q
T
G
T
L
L
P
A
GN
KH
A
W
MC
A
L
NN
F
FN
-
D
P
G
RF
YQ
M
ARL
A
KQDI
E
E
R
F
DIN
K
TA
LK
I
L
T
L
AK
QK
fig|216592.1.peg.16
Escherichia coli 042 (193-361/362)
ML
RPE
KG
HEFML
NL
L
F
H
LK
M
N
G
RQ
F
CWL
I
V
G
S
G
SP
E
L
R
E
H
L
Q
Y
Q
I
D
SM
GM
H
D
D
V
F
IAD
NV
F
P
A
A
P
V
YR
V
---
A
SLVV
LPS
------
EN
E
S
FGMV
L
A
EA
S
A
F
SV
PVV
A
-
T
QI
G
GIPE
VIQ
N
N
Q
T
G
T
L
L
P
A
GN
KH
A
W
MC
A
L
ND
F
FN
-
D
P
G
RF
YQ
M
ARL
A
KQDI
E
E
R
F
DIN
K
TA
LK
I
L
T
L
AK
Q
fig|216592.1.peg.2758
Escherichia coli 042 (193-361/362)
ML
RPE
KG
HEFML
NL
L
F
H
LK
M
N
G
RQ
F
CWL
I
V
G
S
G
SP
E
L
R
E
H
L
Q
Y
Q
I
D
SM
GM
H
D
D
V
F
IAD
NV
F
P
A
A
P
V
YR
V
---
A
SLVV
LPS
------
EN
E
S
FGMV
L
A
EA
S
A
F
SV
PVV
A
-
T
QI
G
GIPE
VIQ
N
N
Q
T
G
T
L
L
P
A
GN
KH
A
W
MC
A
L
ND
F
FN
-
D
P
G
RF
YQ
M
ARL
A
KQDI
E
E
R
F
DIN
K
TA
LK
I
L
T
L
AK
Q
fig|216592.3.peg.4965
Escherichia coli 042 (193-361/362)
ML
RPE
KG
HEFML
NL
L
F
H
LK
M
N
G
RQ
F
CWL
I
V
G
S
G
SP
E
L
R
E
H
L
Q
Y
Q
I
D
SM
GM
H
D
D
V
F
IAD
NV
F
P
A
A
P
V
YR
V
---
A
SLVV
LPS
------
EN
E
S
FGMV
L
A
EA
S
A
F
SV
PVV
A
-
T
QI
G
GIPE
VIQ
N
N
Q
T
G
T
L
L
P
A
GN
KH
A
W
MC
A
L
ND
F
FN
-
D
P
G
RF
YQ
M
ARL
A
KQDI
E
E
R
F
DIN
K
TA
LK
I
L
T
L
AK
Q
fig|331111.12.peg.52
Escherichia coli E24377A (193-362/362)
ML
RPE
KG
HEFML
NL
L
F
H
LK
M
N
G
RQ
F
CWL
I
V
G
S
G
SP
E
L
R
K
H
L
Q
Y
Q
I
D
SM
GM
H
D
D
V
F
IAD
NI
F
P
A
A
P
V
YR
V
---
A
SLVV
LPS
------
EN
E
S
FGMV
L
A
EA
S
A
F
SV
PVV
A
-
T
QI
G
GIPE
VIQ
N
N
Q
T
G
T
L
L
P
A
GN
KH
A
W
MC
A
L
ND
F
FN
-
D
P
G
RF
YQ
M
ARL
A
KQDI
E
E
R
F
DIN
K
TA
LK
I
L
T
L
AK
QK
fig|331111.12.peg.5053
Escherichia coli E24377A
ML
RPE
KG
HEFML
NL
L
F
H
LK
M
N
G
RQ
F
CWL
I
V
G
S
G
SP
E
L
R
E
H
L
Q
Y
Q
I
D
SM
GM
H
D
D
V
F
IAD
NV
F
P
A
A
P
V
YR
V
---
A
SLVV
LPS
------
EN
E
S
FGMV
L
A
EA
S
A
F
SV
PVV
A
-
T
QI
G
GIPE
VIQ
N
N
Q
T
G
T
L
L
P
A
S
N
KH
A
W
MC
A
L
ND
F
FN
-
D
P
G
RF
YQ
M
ARL
A
KQDI
E
E
R
F
DIN
K
TA
LK
I
L
T
L
AK
QK
fig|331111.3.peg.2443
Escherichia coli E24377A (193-362/362)
ML
RPE
KG
HEFML
NL
L
F
H
LK
M
N
G
RQ
F
CWL
I
V
G
S
G
SP
E
L
R
E
H
L
Q
Y
Q
I
D
SM
GM
H
D
D
V
F
IAD
NV
F
P
A
A
P
V
YR
V
---
A
SLVV
LPS
------
EN
E
S
FGMV
L
A
EA
S
A
F
SV
PVV
A
-
T
QI
G
GIPE
VIQ
N
N
Q
T
G
T
L
L
P
A
S
N
KH
A
W
MC
A
L
ND
F
FN
-
D
P
G
RF
YQ
M
ARL
A
KQDI
E
E
R
F
DIN
K
TA
LK
I
L
T
L
AK
QK
fig|749538.3.peg.540
Escherichia coli MS 116-1
ML
RPE
KG
HEFML
NL
L
F
H
LK
M
N
G
RQ
F
CWL
I
V
G
S
G
SP
E
L
R
E
H
L
Q
Y
Q
I
D
SM
GM
H
D
D
V
F
IAD
NV
F
P
A
A
P
V
YR
V
---
A
SLVV
LPS
------
EN
E
S
FGMV
L
A
EA
S
A
F
SV
PVV
A
-
T
QI
G
GIPE
VIQ
N
N
Q
T
G
T
L
L
P
A
S
N
KH
A
W
MC
A
L
ND
F
FN
-
D
P
G
RF
YQ
M
ARL
A
KQDI
E
E
R
F
DIN
K
TA
LK
I
L
T
L
AK
QK
fig|749544.3.peg.615
Escherichia coli MS 175-1
ML
RPE
KG
HEFML
NL
L
F
H
LK
M
N
G
RQ
F
CWL
I
V
G
S
G
SP
E
L
R
E
H
L
Q
Y
Q
I
D
SM
GM
H
D
D
V
F
IAD
NV
F
P
A
A
P
V
YR
V
---
A
SLVV
LPS
------
EN
E
S
FGMV
L
A
EA
S
A
F
SV
PVV
A
-
T
QI
G
GIPE
VIQ
N
N
Q
T
G
T
L
L
P
A
S
N
KH
A
W
MC
A
L
ND
F
FN
-
D
P
G
RF
YQ
M
ARL
A
KQDI
E
E
R
F
DIN
K
TA
LK
I
L
T
L
AK
QK
fig|216592.1.peg.5164
Escherichia coli 042 (193-362/362)
ML
RPE
KG
HEFML
NL
L
F
H
LK
M
N
G
RQ
F
CWL
I
V
G
S
G
SP
E
L
R
E
H
L
Q
Y
Q
I
D
SM
GM
H
D
D
V
F
IAD
NV
F
P
A
A
P
V
YR
V
---
A
SLVV
LPS
------
EN
E
S
FGMV
L
A
EA
S
A
F
SV
PVV
A
-
T
QI
G
GIPE
VIQ
N
N
Q
T
G
T
L
L
P
A
GN
KH
A
W
MC
A
L
ND
F
FN
-
D
P
G
RF
YQ
M
ARL
A
KQDI
E
E
R
F
DIN
K
T
V
LK
I
L
T
L
AKH
K
fig|216592.1.peg.5655
Escherichia coli 042 (193-362/362)
ML
RPE
KG
HEFML
NL
L
F
H
LK
M
N
G
RQ
F
CWL
I
V
G
S
G
SP
E
L
R
E
H
L
Q
Y
Q
I
D
SM
GM
H
D
D
V
F
IAD
NV
F
P
A
A
P
V
YR
V
---
A
SLVV
LPS
------
EN
E
S
FGMV
L
A
EA
S
A
F
SV
PVV
A
-
T
QI
G
GIPE
VIQ
N
N
Q
T
G
T
L
L
P
A
GN
KH
A
W
MC
A
L
ND
F
FN
-
D
P
G
RF
YQ
M
ARL
A
KQDI
E
E
R
F
DIN
K
T
V
LK
I
L
T
L
AKH
K
fig|216592.3.peg.5117
Escherichia coli 042 (193-362/362)
ML
RPE
KG
HEFML
NL
L
F
H
LK
M
N
G
RQ
F
CWL
I
V
G
S
G
SP
E
L
R
E
H
L
Q
Y
Q
I
D
SM
GM
H
D
D
V
F
IAD
NV
F
P
A
A
P
V
YR
V
---
A
SLVV
LPS
------
EN
E
S
FGMV
L
A
EA
S
A
F
SV
PVV
A
-
T
QI
G
GIPE
VIQ
N
N
Q
T
G
T
L
L
P
A
GN
KH
A
W
MC
A
L
ND
F
FN
-
D
P
G
RF
YQ
M
ARL
A
KQDI
E
E
R
F
DIN
K
T
V
LK
I
L
T
L
AKH
K
fig|344610.3.peg.5009
Escherichia coli 53638 (193-362/362)
ML
RPE
KG
HEFML
NL
L
F
H
LK
M
N
G
RQ
F
CWL
I
V
G
S
G
SP
E
L
R
E
H
L
Q
Y
Q
I
D
SM
GM
H
D
D
V
F
IAD
NV
F
P
A
A
P
V
YR
V
---
A
SLVV
LPS
------
EN
E
S
FGMV
L
A
EA
S
A
F
SV
PV
L
A
-
S
QI
G
GIP
DVIQ
N
N
Q
T
G
T
L
L
P
A
GN
KH
A
W
MC
A
L
ND
F
FN
-
D
P
G
RF
YQ
M
ARQ
A
KQDI
E
E
R
F
DIN
K
TA
LK
I
L
T
L
AKH
K
fig|344610.7.peg.152
Escherichia coli 53638 (193-362/362)
ML
RPE
KG
HEFML
NL
L
F
H
LK
M
N
G
RQ
F
CWL
I
V
G
S
G
SP
E
L
R
E
H
L
Q
Y
Q
I
D
SM
GM
H
D
D
V
F
IAD
NV
F
P
A
A
P
V
YR
V
---
A
SLVV
LPS
------
EN
E
S
FGMV
L
A
EA
S
A
F
SV
PV
L
A
-
S
QI
G
GIP
DVIQ
N
N
Q
T
G
T
L
L
P
A
GN
KH
A
W
MC
A
L
ND
F
FN
-
D
P
G
RF
YQ
M
ARQ
A
KQDI
E
E
R
F
DIN
K
TA
LK
I
L
T
L
AKH
K
fig|562.371.peg.2011
Escherichia coli 1044A (193-361/368)
ML
RPE
KG
HEFML
RV
L
Y
QLK
M
E
G
KS
FR
WLVV
G
A
G
RE
E
Y
E
A
RLR
Q
QT
E
HL
GM
S
GD
V
L
M
A
G
AL
F
P
A
L
P
V
YR
I
---
A
S
V
VVM
PS
------
EN
E
A
FGMV
L
A
EA
SV
S
G
V
PV
IA
-
S
ET
G
GIP
DVIQ
K
N
V
T
G
T
L
L
P
V
G
D
VS
A
W
TG
A
L
RD
F
LS
-
RP
E
RF
RM
M
AAS
ARE
DI
E
Y
R
F
DIN
R
TA
QI
I
V
SL
A
SQ
fig|562.373.peg.833
Escherichia coli 1125A (193-361/368)
ML
RPE
KG
HEFML
RV
L
Y
QLK
M
E
G
KS
FR
WLVV
G
A
G
RE
E
Y
E
A
RLR
Q
QT
E
HL
GM
S
GD
V
L
M
A
G
AL
F
P
A
L
P
V
YR
I
---
A
S
V
VVM
PS
------
EN
E
A
FGMV
L
A
EA
SV
S
G
V
PV
IA
-
S
ET
G
GIP
DVIQ
K
N
V
T
G
T
L
L
P
V
G
D
VS
A
W
TG
A
L
RD
F
LS
-
RP
E
RF
RM
M
AAS
ARE
DI
E
Y
R
F
DIN
R
TA
QI
I
V
SL
A
SQ
fig|562.372.peg.387
Escherichia coli 1212A (193-361/368)
ML
RPE
KG
HEFML
RV
L
Y
QLK
M
E
G
KS
FR
WLVV
G
A
G
RE
E
Y
E
A
RLR
Q
QT
E
HL
GM
S
GD
V
L
M
A
G
AL
F
P
A
L
P
V
YR
I
---
A
S
V
VVM
PS
------
EN
E
A
FGMV
L
A
EA
SV
S
G
V
PV
IA
-
S
ET
G
GIP
DVIQ
K
N
V
T
G
T
L
L
P
V
G
D
VS
A
W
TG
A
L
RD
F
LS
-
RP
E
RF
RM
M
AAS
ARE
DI
E
Y
R
F
DIN
R
TA
QI
I
V
SL
A
SQ
fig|562.374.peg.1880
Escherichia coli 536A (193-361/368)
ML
RPE
KG
HEFML
RV
L
Y
QLK
M
E
G
KS
FR
WLVV
G
A
G
RE
E
Y
E
A
RLR
Q
QT
E
HL
GM
S
GD
V
L
M
A
G
AL
F
P
A
L
P
V
YR
I
---
A
S
V
VVM
PS
------
EN
E
A
FGMV
L
A
EA
SV
S
G
V
PV
IA
-
S
ET
G
GIP
DVIQ
K
N
V
T
G
T
L
L
P
V
G
D
VS
A
W
TG
A
L
RD
F
LS
-
RP
E
RF
RM
M
AAS
ARE
DI
E
Y
R
F
DIN
R
TA
QI
I
V
SL
A
SQ
fig|585396.4.peg.5781
Escherichia coli O111:H- str. 11128 (193-361/368)
ML
RPE
KG
HEFML
RV
L
Y
QLK
M
E
G
KS
FR
WLVV
G
A
G
RE
E
Y
E
A
RLR
Q
QT
E
HL
GM
S
GD
V
L
M
A
G
AL
F
P
A
L
P
V
YR
I
---
A
S
V
VVM
PS
------
EN
E
A
FGMV
L
A
EA
SV
S
G
V
PV
IA
-
S
ET
G
GIP
DVIQ
K
N
V
T
G
T
L
L
P
V
G
D
VS
A
W
TG
A
L
RD
F
LS
-
RP
E
RF
RM
M
AAS
ARE
DI
E
Y
R
F
DIN
R
TA
QI
I
V
SL
A
SQ
fig|83334.1.peg.85
Escherichia coli O157:H7 (193-361/368)
ML
RPE
KG
HEFML
RV
L
Y
QLK
M
E
G
KS
FR
WLVV
G
A
G
RE
E
Y
E
A
RLR
Q
QT
E
HL
GM
S
GD
V
L
M
A
G
AL
F
P
A
L
P
V
YR
I
---
A
S
V
VVM
PS
------
EN
E
A
FGMV
L
A
EA
SV
S
G
V
PV
IA
-
S
ET
G
GIP
DVIQ
K
N
V
T
G
T
L
L
P
V
G
D
VS
A
W
TG
A
L
RD
F
LS
-
RP
E
RF
RM
M
AAS
ARE
DI
E
Y
R
F
DIN
R
TA
QI
I
V
SL
A
SQ
fig|155864.8.peg.5615
Escherichia coli O157:H7 EDL933 (193-361/368)
ML
RPE
KG
HEFML
RV
L
Y
QLK
M
E
G
KS
FR
WLVV
G
A
G
RE
E
Y
E
A
RLR
Q
QT
E
HL
GM
S
GD
V
L
M
A
G
AL
F
P
A
L
P
V
YR
I
---
A
S
V
VVM
PS
------
EN
E
A
FGMV
L
A
EA
SV
S
G
V
PV
IA
-
S
ET
G
GIP
DVIQ
K
N
V
T
G
T
L
L
P
V
G
D
VS
A
W
TG
A
L
RD
F
LS
-
RP
E
RF
RM
M
AAS
ARE
DI
E
Y
R
F
DIN
R
TA
QI
I
V
SL
A
SQ
fig|444454.5.peg.641
Escherichia coli O157:H7 str. EC4024 (193-361/368)
ML
RPE
KG
HEFML
RV
L
Y
QLK
M
E
G
KS
FR
WLVV
G
A
G
RE
E
Y
E
A
RLR
Q
QT
E
HL
GM
S
GD
V
L
M
A
G
AL
F
P
A
L
P
V
YR
I
---
A
S
V
VVM
PS
------
EN
E
A
FGMV
L
A
EA
SV
S
G
V
PV
IA
-
S
ET
G
GIP
DVIQ
K
N
V
T
G
T
L
L
P
V
G
D
VS
A
W
TG
A
L
RD
F
LS
-
RP
E
RF
RM
M
AAS
ARE
DI
E
Y
R
F
DIN
R
TA
QI
I
V
SL
A
SQ
fig|444449.5.peg.5675
Escherichia coli O157:H7 str. EC4042 (170-338/345)
ML
RPE
KG
HEFML
RV
L
Y
QLK
M
E
G
KS
FR
WLVV
G
A
G
RE
E
Y
E
A
RLR
Q
QT
E
HL
GM
S
GD
V
L
M
A
G
AL
F
P
A
L
P
V
YR
I
---
A
S
V
VVM
PS
------
EN
E
A
FGMV
L
A
EA
SV
S
G
V
PV
IA
-
S
ET
G
GIP
DVIQ
K
N
V
T
G
T
L
L
P
V
G
D
VS
A
W
TG
A
L
RD
F
LS
-
RP
E
RF
RM
M
AAS
ARE
DI
E
Y
R
F
DIN
R
TA
QI
I
V
SL
A
SQ
fig|444448.5.peg.5656
Escherichia coli O157:H7 str. EC4045 (193-361/368)
ML
RPE
KG
HEFML
RV
L
Y
QLK
M
E
G
KS
FR
WLVV
G
A
G
RE
E
Y
E
A
RLR
Q
QT
E
HL
GM
S
GD
V
L
M
A
G
AL
F
P
A
L
P
V
YR
I
---
A
S
V
VVM
PS
------
EN
E
A
FGMV
L
A
EA
SV
S
G
V
PV
IA
-
S
ET
G
GIP
DVIQ
K
N
V
T
G
T
L
L
P
V
G
D
VS
A
W
TG
A
L
RD
F
LS
-
RP
E
RF
RM
M
AAS
ARE
DI
E
Y
R
F
DIN
R
TA
QI
I
V
SL
A
SQ
fig|444453.5.peg.4370
Escherichia coli O157:H7 str. EC4076 (170-338/345)
ML
RPE
KG
HEFML
RV
L
Y
QLK
M
E
G
KS
FR
WLVV
G
A
G
RE
E
Y
E
A
RLR
Q
QT
E
HL
GM
S
GD
V
L
M
A
G
AL
F
P
A
L
P
V
YR
I
---
A
S
V
VVM
PS
------
EN
E
A
FGMV
L
A
EA
SV
S
G
V
PV
IA
-
S
ET
G
GIP
DVIQ
K
N
V
T
G
T
L
L
P
V
G
D
VS
A
W
TG
A
L
RD
F
LS
-
RP
E
RF
RM
M
AAS
ARE
DI
E
Y
R
F
DIN
R
TA
QI
I
V
SL
A
SQ
fig|444452.5.peg.3629
Escherichia coli O157:H7 str. EC4113 (170-338/345)
ML
RPE
KG
HEFML
RV
L
Y
QLK
M
E
G
KS
FR
WLVV
G
A
G
RE
E
Y
E
A
RLR
Q
QT
E
HL
GM
S
GD
V
L
M
A
G
AL
F
P
A
L
P
V
YR
I
---
A
S
V
VVM
PS
------
EN
E
A
FGMV
L
A
EA
SV
S
G
V
PV
IA
-
S
ET
G
GIP
DVIQ
K
N
V
T
G
T
L
L
P
V
G
D
VS
A
W
TG
A
L
RD
F
LS
-
RP
E
RF
RM
M
AAS
ARE
DI
E
Y
R
F
DIN
R
TA
QI
I
V
SL
A
SQ
fig|444450.8.peg.82
Escherichia coli O157:H7 str. EC4115 (170-338/345)
ML
RPE
KG
HEFML
RV
L
Y
QLK
M
E
G
KS
FR
WLVV
G
A
G
RE
E
Y
E
A
RLR
Q
QT
E
HL
GM
S
GD
V
L
M
A
G
AL
F
P
A
L
P
V
YR
I
---
A
S
V
VVM
PS
------
EN
E
A
FGMV
L
A
EA
SV
S
G
V
PV
IA
-
S
ET
G
GIP
DVIQ
K
N
V
T
G
T
L
L
P
V
G
D
VS
A
W
TG
A
L
RD
F
LS
-
RP
E
RF
RM
M
AAS
ARE
DI
E
Y
R
F
DIN
R
TA
QI
I
V
SL
A
SQ
fig|444451.5.peg.4171
Escherichia coli O157:H7 str. EC4196 (193-361/368)
ML
RPE
KG
HEFML
RV
L
Y
QLK
M
E
G
KS
FR
WLVV
G
A
G
RE
E
Y
E
A
RLR
Q
QT
E
HL
GM
S
GD
V
L
M
A
G
AL
F
P
A
L
P
V
YR
I
---
A
S
V
VVM
PS
------
EN
E
A
FGMV
L
A
EA
SV
S
G
V
PV
IA
-
S
ET
G
GIP
DVIQ
K
N
V
T
G
T
L
L
P
V
G
D
VS
A
W
TG
A
L
RD
F
LS
-
RP
E
RF
RM
M
AAS
ARE
DI
E
Y
R
F
DIN
R
TA
QI
I
V
SL
A
SQ
fig|444447.5.peg.5736
Escherichia coli O157:H7 str. EC4206 (170-338/345)
ML
RPE
KG
HEFML
RV
L
Y
QLK
M
E
G
KS
FR
WLVV
G
A
G
RE
E
Y
E
A
RLR
Q
QT
E
HL
GM
S
GD
V
L
M
A
G
AL
F
P
A
L
P
V
YR
I
---
A
S
V
VVM
PS
------
EN
E
A
FGMV
L
A
EA
SV
S
G
V
PV
IA
-
S
ET
G
GIP
DVIQ
K
N
V
T
G
T
L
L
P
V
G
D
VS
A
W
TG
A
L
RD
F
LS
-
RP
E
RF
RM
M
AAS
ARE
DI
E
Y
R
F
DIN
R
TA
QI
I
V
SL
A
SQ
fig|478004.5.peg.4005
Escherichia coli O157:H7 str. EC4401 (170-338/345)
ML
RPE
KG
HEFML
RV
L
Y
QLK
M
E
G
KS
FR
WLVV
G
A
G
RE
E
Y
E
A
RLR
Q
QT
E
HL
GM
S
GD
V
L
M
A
G
AL
F
P
A
L
P
V
YR
I
---
A
S
V
VVM
PS
------
EN
E
A
FGMV
L
A
EA
SV
S
G
V
PV
IA
-
S
ET
G
GIP
DVIQ
K
N
V
T
G
T
L
L
P
V
G
D
VS
A
W
TG
A
L
RD
F
LS
-
RP
E
RF
RM
M
AAS
ARE
DI
E
Y
R
F
DIN
R
TA
QI
I
V
SL
A
SQ
fig|478005.5.peg.3236
Escherichia coli O157:H7 str. EC4486 (170-338/345)
ML
RPE
KG
HEFML
RV
L
Y
QLK
M
E
G
KS
FR
WLVV
G
A
G
RE
E
Y
E
A
RLR
Q
QT
E
HL
GM
S
GD
V
L
M
A
G
AL
F
P
A
L
P
V
YR
I
---
A
S
V
VVM
PS
------
EN
E
A
FGMV
L
A
EA
SV
S
G
V
PV
IA
-
S
ET
G
GIP
DVIQ
K
N
V
T
G
T
L
L
P
V
G
D
VS
A
W
TG
A
L
RD
F
LS
-
RP
E
RF
RM
M
AAS
ARE
DI
E
Y
R
F
DIN
R
TA
QI
I
V
SL
A
SQ
fig|478006.5.peg.3450
Escherichia coli O157:H7 str. EC4501 (193-361/368)
ML
RPE
KG
HEFML
RV
L
Y
QLK
M
E
G
KS
FR
WLVV
G
A
G
RE
E
Y
E
A
RLR
Q
QT
E
HL
GM
S
GD
V
L
M
A
G
AL
F
P
A
L
P
V
YR
I
---
A
S
V
VVM
PS
------
EN
E
A
FGMV
L
A
EA
SV
S
G
V
PV
IA
-
S
ET
G
GIP
DVIQ
K
N
V
T
G
T
L
L
P
V
G
D
VS
A
W
TG
A
L
RD
F
LS
-
RP
E
RF
RM
M
AAS
ARE
DI
E
Y
R
F
DIN
R
TA
QI
I
V
SL
A
SQ
fig|478007.5.peg.3844
Escherichia coli O157:H7 str. EC508 (193-361/368)
ML
RPE
KG
HEFML
RV
L
Y
QLK
M
E
G
KS
FR
WLVV
G
A
G
RE
E
Y
E
A
RLR
Q
QT
E
HL
GM
S
GD
V
L
M
A
G
AL
F
P
A
L
P
V
YR
I
---
A
S
V
VVM
PS
------
EN
E
A
FGMV
L
A
EA
SV
S
G
V
PV
IA
-
S
ET
G
GIP
DVIQ
K
N
V
T
G
T
L
L
P
V
G
D
VS
A
W
TG
A
L
RD
F
LS
-
RP
E
RF
RM
M
AAS
ARE
DI
E
Y
R
F
DIN
R
TA
QI
I
V
SL
A
SQ
fig|478007.5.peg.5204
Escherichia coli O157:H7 str. EC508 (193-361/368)
ML
RPE
KG
HEFML
RV
L
Y
QLK
M
E
G
KS
FR
WLVV
G
A
G
RE
E
Y
E
A
RLR
Q
QT
E
HL
GM
S
GD
V
L
M
A
G
AL
F
P
A
L
P
V
YR
I
---
A
S
V
VVM
PS
------
EN
E
A
FGMV
L
A
EA
SV
S
G
V
PV
IA
-
S
ET
G
GIP
DVIQ
K
N
V
T
G
T
L
L
P
V
G
D
VS
A
W
TG
A
L
RD
F
LS
-
RP
E
RF
RM
M
AAS
ARE
DI
E
Y
R
F
DIN
R
TA
QI
I
V
SL
A
SQ
fig|478008.5.peg.4936
Escherichia coli O157:H7 str. EC869 (193-361/368)
ML
RPE
KG
HEFML
RV
L
Y
QLK
M
E
G
KS
FR
WLVV
G
A
G
RE
E
Y
E
A
RLR
Q
QT
E
HL
GM
S
GD
V
L
M
A
G
AL
F
P
A
L
P
V
YR
I
---
A
S
V
VVM
PS
------
EN
E
A
FGMV
L
A
EA
SV
S
G
V
PV
IA
-
S
ET
G
GIP
DVIQ
K
N
V
T
G
T
L
L
P
V
G
D
VS
A
W
TG
A
L
RD
F
LS
-
RP
E
RF
RM
M
AAS
ARE
DI
E
Y
R
F
DIN
R
TA
QI
I
V
SL
A
SQ
fig|637388.3.peg.2752
Escherichia coli O157:H7 str. FRIK2000 (193-361/368)
ML
RPE
KG
HEFML
RV
L
Y
QLK
M
E
G
KS
FR
WLVV
G
A
G
RE
E
Y
E
A
RLR
Q
QT
E
HL
GM
S
GD
V
L
M
A
G
AL
F
P
A
L
P
V
YR
I
---
A
S
V
VVM
PS
------
EN
E
A
FGMV
L
A
EA
SV
S
G
V
PV
IA
-
S
ET
G
GIP
DVIQ
K
N
V
T
G
T
L
L
P
V
G
D
VS
A
W
TG
A
L
RD
F
LS
-
RP
E
RF
RM
M
AAS
ARE
DI
E
Y
R
F
DIN
R
TA
QI
I
V
SL
A
SQ
fig|570506.3.peg.3835
Escherichia coli O157:H7 str. FRIK966 (170-338/345)
ML
RPE
KG
HEFML
RV
L
Y
QLK
M
E
G
KS
FR
WLVV
G
A
G
RE
E
Y
E
A
RLR
Q
QT
E
HL
GM
S
GD
V
L
M
A
G
AL
F
P
A
L
P
V
YR
I
---
A
S
V
VVM
PS
------
EN
E
A
FGMV
L
A
EA
SV
S
G
V
PV
IA
-
S
ET
G
GIP
DVIQ
K
N
V
T
G
T
L
L
P
V
G
D
VS
A
W
TG
A
L
RD
F
LS
-
RP
E
RF
RM
M
AAS
ARE
DI
E
Y
R
F
DIN
R
TA
QI
I
V
SL
A
SQ
fig|386585.9.peg.95
Escherichia coli O157:H7 str. Sakai (170-338/345)
ML
RPE
KG
HEFML
RV
L
Y
QLK
M
E
G
KS
FR
WLVV
G
A
G
RE
E
Y
E
A
RLR
Q
QT
E
HL
GM
S
GD
V
L
M
A
G
AL
F
P
A
L
P
V
YR
I
---
A
S
V
VVM
PS
------
EN
E
A
FGMV
L
A
EA
SV
S
G
V
PV
IA
-
S
ET
G
GIP
DVIQ
K
N
V
T
G
T
L
L
P
V
G
D
VS
A
W
TG
A
L
RD
F
LS
-
RP
E
RF
RM
M
AAS
ARE
DI
E
Y
R
F
DIN
R
TA
QI
I
V
SL
A
SQ
fig|544404.4.peg.5654
Escherichia coli O157:H7 str. TW14359 (193-361/368)
ML
RPE
KG
HEFML
RV
L
Y
QLK
M
E
G
KS
FR
WLVV
G
A
G
RE
E
Y
E
A
RLR
Q
QT
E
HL
GM
S
GD
V
L
M
A
G
AL
F
P
A
L
P
V
YR
I
---
A
S
V
VVM
PS
------
EN
E
A
FGMV
L
A
EA
SV
S
G
V
PV
IA
-
S
ET
G
GIP
DVIQ
K
N
V
T
G
T
L
L
P
V
G
D
VS
A
W
TG
A
L
RD
F
LS
-
RP
E
RF
RM
M
AAS
ARE
DI
E
Y
R
F
DIN
R
TA
QI
I
V
SL
A
SQ
fig|502346.5.peg.5693
Escherichia coli O157:H7 str. TW14588 (193-361/368)
ML
RPE
KG
HEFML
RV
L
Y
QLK
M
E
G
KS
FR
WLVV
G
A
G
RE
E
Y
E
A
RLR
Q
QT
E
HL
GM
S
GD
V
L
M
A
G
AL
F
P
A
L
P
V
YR
I
---
A
S
V
VVM
PS
------
EN
E
A
FGMV
L
A
EA
SV
S
G
V
PV
IA
-
S
ET
G
GIP
DVIQ
K
N
V
T
G
T
L
L
P
V
G
D
VS
A
W
TG
A
L
RD
F
LS
-
RP
E
RF
RM
M
AAS
ARE
DI
E
Y
R
F
DIN
R
TA
QI
I
V
SL
A
SQ
fig|573235.3.peg.5980
Escherichia coli O26:H11 str. 11368 (193-361/368)
ML
RPE
KG
HEFML
RV
L
Y
QLK
M
E
G
KS
FR
WLVV
G
A
G
RE
E
Y
E
A
RLR
Q
QT
E
HL
GM
S
GD
V
L
M
A
G
AL
F
P
A
L
P
V
YR
I
---
A
S
V
VVM
PS
------
EN
E
A
FGMV
L
A
EA
SV
S
G
V
PV
IA
-
S
ET
G
GIP
DVIQ
K
N
V
T
G
T
L
L
P
V
G
D
VS
A
W
TG
A
L
RD
F
LS
-
RP
E
RF
RM
M
AAS
ARE
DI
E
Y
R
F
DIN
R
TA
QI
I
V
SL
A
SQ
fig|585395.4.peg.5547
Escherichia coli O103:H2 str. 12009 (170-338/345)
ML
RPE
KG
HEFML
RV
L
Y
QLK
M
E
G
KS
FR
WLVV
G
A
G
RE
E
Y
E
A
RLR
Q
QT
E
HL
GM
S
GD
V
L
M
A
G
AL
F
P
A
L
P
V
YR
I
---
A
S
V
VVM
PS
------
EN
E
A
FGMV
L
A
EA
SV
S
G
V
PV
IA
-
S
ET
G
GIP
DVIQ
K
N
V
T
G
T
L
L
P
V
G
D
VS
A
W
TG
A
L
RD
F
LS
-
RP
E
RF
RM
M
AAS
ARE
DI
E
C
R
F
DIN
R
TA
QI
I
V
SL
A
SQ
fig|679205.4.peg.2997
Escherichia coli MS 124-1 (201-368/378)
L
V
EKKG
TSTL
I
SA
M
R
N
I
S
K
N
F
PE
YK
LI
I
I
G
E
G
--
P
L
Q
E
Q
L
L
E
Q
A
K
EL
N
L
E
N
N
I
S
FL
G
-A
K
SH
A
EV
MQW
M
RK
A
SL
L
V
LPS
I
T
AK
N
GD
A
E
G
L
GMV
L
L
EA
A
A
T
G
V
P
L
I
G
-
T
NH
G
GIPE
VI
K
D
S
I
N
G
Y
LV
N
E
ND
AD
M
L
QD
R
I
SY
L
LN
N
D
S
V
R
-
HQ
M
GRA
AR
D
V
I
N
R
DFN
I
H
I
Q
S
AK
L
fig|749533.3.peg.460
Escherichia coli MS 84-1 (201-368/378)
L
V
EKKG
TSTL
I
SA
M
R
N
I
S
K
N
F
PE
YK
LI
I
I
G
E
G
--
P
L
Q
E
Q
L
L
E
Q
A
K
EL
N
L
E
N
N
I
S
FL
G
-A
K
SH
A
EV
MQW
M
RK
A
SL
L
V
LPS
I
T
AK
N
GD
A
E
G
L
GMV
L
L
EA
A
A
T
G
V
P
L
I
G
-
T
NH
G
GIPE
VI
K
D
S
I
N
G
Y
LV
N
E
ND
AD
M
L
QD
R
I
SY
L
LN
N
D
S
V
R
-
HQ
M
GRA
AR
D
V
I
N
R
DFN
I
H
I
Q
S
AK
L
fig|6666666.5357.peg.2854
Escherichia coli TY-2482 (204-376/379)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLD
N
ADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AH
AL
AQ
RL
AA
F
SN
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|1040638.4.peg.3118
Escherichia coli O104:H4 str. LB226692 (72-244/247)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLD
N
ADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AH
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|585055.6.peg.2335
Escherichia coli 55989 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLD
N
ADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AH
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|585055.8.peg.2342
Escherichia coli 55989 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLD
N
ADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AH
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|670897.3.peg.2957
Escherichia coli 2362-75 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
MA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
D
MPG
-F
KPS
H
EVK
E
MLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AT
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|701177.3.peg.2588
Escherichia coli O55:H7 str. CB9615 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
MA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
D
MPG
-F
KPS
H
EVK
E
MLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AT
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|749540.3.peg.84
Escherichia coli MS 146-1 (233-403/408)
LTEKKG
I
KY
AI
SA
C
N
I
L
NR
A
G
YN
F
H
Y
T
I
I
G
Y
G
--
E
L
L
D
E
L
N
K
M
I
I
DL
D
L
K
SK
V
D
I
I
G
-F
Q
P
Q
S
I
VK
K
ML
S
NS
DVFLLPSVT
A
SN
GDME
G
IPVALMEAMA
T
G
L
PV
I
S
-
S
YH
SGIPEL
IQ
N
D
Y
SGWL
CQ
E
GN
SQ
E
I
AN
C
I
IK
L
IE
-
D
K
V
E
I
ND
I
EKN
AR
NH
I
E
L
N
FNQ
D
N
EY
NK
M
A
T
M
fig|685038.3.peg.2097
Escherichia coli O83:H1 str. NRG 857C (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVK
E
MLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
T
GWLVP
E
ND
AR
AL
AQ
RL
AV
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|714962.3.peg.2314
Escherichia coli IHE3034 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AT
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|749528.3.peg.3365
Escherichia coli MS 45-1 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AT
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|869729.3.peg.1400
Escherichia coli UM146 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AT
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|364106.7.peg.2341
Escherichia coli UTI89 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AT
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|364106.8.peg.2344
Escherichia coli UTI89 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AT
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|656393.3.peg.3046
Escherichia coli H299 (193-346/356)
L
EY
Q
KG
FD
I
L
I
DI
F
A
RV
N
K
E
H
PG
W
ELH
I
Y
G
V
G
--
T
C
E
E
F
LR
D
K
I
N
QY
K
L
-
N
N
I
K
L
M
G
CV
D--
-
N
IQ
LYYPKY
S
VF
V
FS
S
------
RF
E
G
FGMV
L
L
EAM
E
C
G
L
P
C
I
S
FD
CP
T
G
PS
E
IL
G
N
G
Q
Y
G
I
LV
E
N
GN
VT
KF
SA
E
L
AD
L
MS
-
D
K
E
K
K
IK
L
SNI
S
K
T
R
A
K
-
E
F
H
I
D
K
fig|362663.8.peg.2095
Escherichia coli 536 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DV
I
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AC
AL
AQ
RL
AA
F
SQ
LDT
D
EL
TT
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|362663.9.peg.2100
Escherichia coli 536 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DV
I
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AC
AL
AQ
RL
AA
F
SQ
LDT
D
EL
TT
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|405955.13.peg.2227
Escherichia coli APEC O1 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DV
I
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AC
AL
AQ
RL
AA
F
SQ
LDT
D
EL
TT
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|405955.9.peg.1814
Escherichia coli APEC O1 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DV
I
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AC
AL
AQ
RL
AA
F
SQ
LDT
D
EL
TT
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|413997.3.peg.2042
Escherichia coli B str. REL606 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DV
I
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AC
AL
AQ
RL
AA
F
SQ
LDT
D
EL
TT
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|511693.5.peg.2072
Escherichia coli BL21 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DV
I
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AC
AL
AQ
RL
AA
F
SQ
LDT
D
EL
TT
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|469008.4.peg.1659
Escherichia coli BL21(DE3) (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DV
I
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AC
AL
AQ
RL
AA
F
SQ
LDT
D
EL
TT
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|199310.1.peg.2500
Escherichia coli CFT073 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DV
I
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AC
AL
AQ
RL
AA
F
SQ
LDT
D
EL
TT
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|199310.4.peg.2413
Escherichia coli CFT073 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DV
I
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AC
AL
AQ
RL
AA
F
SQ
LDT
D
EL
TT
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|340197.3.peg.104
Escherichia coli F11 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DV
I
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AC
AL
AQ
RL
AA
F
SQ
LDT
D
EL
TT
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|340197.5.peg.108
Escherichia coli F11 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DV
I
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AC
AL
AQ
RL
AA
F
SQ
LDT
D
EL
TT
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|585057.4.peg.1025
Escherichia coli IAI39 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DV
I
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AC
AL
AQ
RL
AA
F
SQ
LDT
D
EL
TT
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|585057.6.peg.1022
Escherichia coli IAI39 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DV
I
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AC
AL
AQ
RL
AA
F
SQ
LDT
D
EL
TT
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|749547.3.peg.2564
Escherichia coli MS 187-1 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DV
I
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AC
AL
AQ
RL
AA
F
SQ
LDT
D
EL
TT
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|749549.3.peg.775
Escherichia coli MS 198-1 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DV
I
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AC
AL
AQ
RL
AA
F
SQ
LDT
D
EL
TT
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|749550.3.peg.1618
Escherichia coli MS 200-1 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DV
I
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AC
AL
AQ
RL
AA
F
SQ
LDT
D
EL
TT
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|749527.3.peg.1547
Escherichia coli MS 21-1 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DV
I
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AC
AL
AQ
RL
AA
F
SQ
LDT
D
EL
TT
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|656440.3.peg.2027
Escherichia coli TA206 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AV
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|670888.3.peg.4244
Escherichia coli 1827-70 (231-402/406)
LTEKKGLHVAI
EA
C
R
QLK
A
R
G
VD
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
E
L
E
TH
V
E
MPG
-F
KPS
H
EVKAMLD
E
ADVFLLPSVTGADG
N
ME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPEL
I
K
S
D
H
SGWLVP
E
N
N
AM
AL
AD
RL
AA
F
SD
I
D
Q
Q
A
L
EP
V
LHN
AR
Q
KVE
A
DFNQQ
V
IN
RK
L
A
SL
fig|344610.3.peg.2060
Escherichia coli 53638 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DV
I
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AT
F
SQ
L
N
T
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|344610.7.peg.4432
Escherichia coli 53638 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DV
I
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AT
F
SQ
L
N
T
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|409438.11.peg.2469
Escherichia coli SE11 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVK
S
MLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
T
GWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
N
EL
AP
V
IKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|679206.4.peg.1626
Escherichia coli MS 119-7 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLD
N
ADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|585035.6.peg.2121
Escherichia coli S88 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
L
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
VA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|585397.7.peg.2405
Escherichia coli ED1a (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLD
N
ADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
IKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|585397.9.peg.2403
Escherichia coli ED1a (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLD
N
ADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
IKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|431946.3.peg.2018
Escherichia coli SE15 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVK
E
MLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|525281.3.peg.3845
Escherichia coli 83972 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTG
V
DGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|655817.3.peg.2484
Escherichia coli ABU 83972 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTG
V
DGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|562.375.peg.2262
Escherichia coli EC4100B (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
MA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|656419.3.peg.2795
Escherichia coli M718 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
MA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|340185.3.peg.1169
Escherichia coli E22 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
MA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|340185.4.peg.1235
Escherichia coli E22 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
MA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|585395.4.peg.2640
Escherichia coli O103:H2 str. 12009 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
MA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|550672.3.peg.1763
Escherichia coli B088 (40-212/215)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
MA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|749546.3.peg.3762
Escherichia coli MS 185-1 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
S
V
L
fig|585034.4.peg.2096
Escherichia coli IAI1 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DV
I
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|585034.5.peg.2091
Escherichia coli IAI1 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DV
I
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|656443.3.peg.2742
Escherichia coli TA271 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DV
I
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|331111.12.peg.2617
Escherichia coli E24377A (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|331111.3.peg.78
Escherichia coli E24377A (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|358709.5.peg.493
Escherichia coli 101-1 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|562.371.peg.4245
Escherichia coli 1044A (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|562.373.peg.4643
Escherichia coli 1125A (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|562.372.peg.5816
Escherichia coli 1212A (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|562.374.peg.1755
Escherichia coli 536A (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|550676.3.peg.2341
Escherichia coli B185 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|550677.3.peg.1594
Escherichia coli B354 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLD
E
ADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|595496.3.peg.2012
Escherichia coli BW2952 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|536056.3.peg.1701
Escherichia coli DH1 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|83333.1.peg.2020
Escherichia coli K12 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|656417.3.peg.2709
Escherichia coli M605 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|749548.3.peg.2895
Escherichia coli MS 196-1 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|83334.1.peg.2856
Escherichia coli O157:H7 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|155864.1.peg.2858
Escherichia coli O157:H7 EDL933 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|155864.8.peg.2742
Escherichia coli O157:H7 EDL933 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|444454.5.peg.1712
Escherichia coli O157:H7 str. EC4024 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|444449.5.peg.1190
Escherichia coli O157:H7 str. EC4042 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|444448.5.peg.5464
Escherichia coli O157:H7 str. EC4045 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|444453.5.peg.3683
Escherichia coli O157:H7 str. EC4076 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|444452.5.peg.3402
Escherichia coli O157:H7 str. EC4113 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|444450.8.peg.2984
Escherichia coli O157:H7 str. EC4115 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|444451.5.peg.3091
Escherichia coli O157:H7 str. EC4196 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|444447.5.peg.85
Escherichia coli O157:H7 str. EC4206 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|478004.5.peg.4221
Escherichia coli O157:H7 str. EC4401 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|478005.5.peg.3651
Escherichia coli O157:H7 str. EC4486 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|478006.5.peg.2269
Escherichia coli O157:H7 str. EC4501 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|478007.5.peg.1850
Escherichia coli O157:H7 str. EC508 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|478008.5.peg.3868
Escherichia coli O157:H7 str. EC869 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|637388.3.peg.2227
Escherichia coli O157:H7 str. FRIK2000 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|570506.3.peg.3439
Escherichia coli O157:H7 str. FRIK966 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|386585.9.peg.2982
Escherichia coli O157:H7 str. Sakai (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|544404.4.peg.2846
Escherichia coli O157:H7 str. TW14359 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|502346.5.peg.4536
Escherichia coli O157:H7 str. TW14588 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|573235.3.peg.3018
Escherichia coli O26:H11 str. 11368 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|316407.3.peg.1980
Escherichia coli W3110 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|316385.5.peg.2159
Escherichia coli str. K-12 substr. DH10B (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|316385.7.peg.2209
Escherichia coli str. K-12 substr. DH10B (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|511145.12.peg.2121
Escherichia coli str. K-12 substr. MG1655 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|511145.6.peg.2106
Escherichia coli str. K-12 substr. MG1655 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|481805.3.peg.1711
Escherichia coli ATCC 8739 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|481805.6.peg.1705
Escherichia coli ATCC 8739 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|656379.3.peg.2572
Escherichia coli FVEC1302 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|656380.3.peg.3487
Escherichia coli FVEC1412 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|679207.4.peg.1678
Escherichia coli MS 107-1 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPS
I
TGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|749545.3.peg.4269
Escherichia coli MS 182-1 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|656437.3.peg.2301
Escherichia coli TA143 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|585056.7.peg.2561
Escherichia coli UMN026 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|562.376.peg.1083
Escherichia coli WV_060327 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|749537.3.peg.3755
Escherichia coli MS 115-1 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
N
EL
AP
V
IKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|316401.4.peg.2506
Escherichia coli ETEC H10407 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DV
I
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
IKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|753642.3.peg.3048
Escherichia coli NC101 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RL
S
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
VKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|656408.3.peg.2245
Escherichia coli H591 (657-829/832)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
IKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|656444.3.peg.3012
Escherichia coli TA280 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
D
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
IKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|340184.3.peg.2790
Escherichia coli B7A (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
IKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|340184.6.peg.2920
Escherichia coli B7A (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
IKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|595495.4.peg.2981
Escherichia coli KO11 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
IKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|566546.3.peg.2535
Escherichia coli W (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
IKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|566546.4.peg.2185
Escherichia coli W (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
IKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|749532.3.peg.3846
Escherichia coli MS 78-1 (231-403/406)
LTEKKGLHVAI
EA
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
IKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|216592.1.peg.2834
Escherichia coli 042 (231-403/406)
LTEKKGLHVAI
ES
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
IKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|216592.3.peg.2380
Escherichia coli 042 (231-403/406)
LTEKKGLHVAI
ES
C
R
QLKE
Q
G
VA
FRYRILG
I
G
--
P
W
E
R
RLR
T
LIE
QY
QL
E
DVV
E
MPG
-F
KPS
H
EVKAMLDDADVFLLPSVTGADGDME
G
IPVALMEAMA
V
GIPVVS
-
T
LH
SGIPELVE
A
D
K
SGWLVP
E
ND
AR
AL
AQ
RL
AA
F
SQ
LDT
D
EL
AP
V
IKR
AREKVE
H
DFNQQ
V
IN
RE
L
A
SLL
fig|550672.3.peg.1754
Escherichia coli B088 (220-379/383)
KKG
FVK
ML
NT
F
E
I
M
K
S
M
N
EN
L
K
W
M
I
V
G
D
G
--
G
F
L
E
S
L
K
E
I
AF
RK
G
I
F
D
S
L
I
I
V
G
-K
I
P
R
S
E
L
CMFY
N
S
AD
I
F
W
L
L
S
-----
EYQ
E
A
FG
L
V
Y
I
E
S
Q
A
C
G
V
P
A
I
G
-
Y
NN
SG
V
R
E
A
V
V
D
G
V
T
G
Y
L
I
N
N
L
D
--
--
--
E
M
LD
I
VV
-
-
T
K
K
F
QI
I
TNE
S
LY
D
FS
K
K
F
D
S
K
Q
CY
LK
I
L
KAF
NE
K
Consen1
Primary consensus
MLtekKGlhvai
c
qLKe
G
FryrilG
G
p
e
rLr
lie
ql
dvv
mpg
kPs
eVkamlddAdvfllPSvtgadgdmE
ipvaLmEAma
giPVvs
-
t
sGIPelve
d
sGwLvP
nd
Al
rL
F
ldt
el
v
ArekvE
dFnqq
in
l
sLlsqK
Consen2
Secondary consensus
rpe
hefml
l
h
m
cwlvv
e
r
h
q
qtd
gm
gdi
iad
f
a
p
yr
---
slvvm
------
en
fgmv
a
sv
sv
ia
s
g
dviq
n
t
t
l
gn
w
a
-
rp
rf
m
kqdi
r
din
ta
i
t
akh
Consensus 1
(when a gap)
Conservative difference
Consensus 2
(when a gap)
Nonconservative diff.
Other character