fig|1040638.4.peg.625
Escherichia coli O104:H4 str. LB226692
M
LAGIG
G
V
NSNAP
S
VN
DI
GN
TL
Q
LIRQNN
D
I
ERSG
A
NNVGLTALQGL
S
G
I
A
GGVQ
Q
E
KQ
A
Q
R
QK
E
FQ
Q
A
YA
N
A
Y
ASGDR
GA
LR
Q
L
AT
Q
YP
DQI
E
SV
R
K
GM
GFI
DE
E
QRNSIG
T
LA
AG
A
R
LA
S
S
-
SPEAMQS
CCKT
TPRN
fig|585396.4.peg.2776
Escherichia coli O111:H- str. 11128 (11-140/468)
L
LAGIG
G
V
NSNAP
S
VN
DI
GN
TL
Q
LIRQNN
D
I
ERSG
A
NNVGLTALQGL
S
G
I
A
GVFQ
Q
E
KQ
A
Q
R
QK
E
FQ
Q
A
YA
N
A
Y
ASGDR
GA
LR
Q
L
AT
Q
YP
DQI
E
SV
R
K
GM
GFI
DEDQRNSIG
T
LA
AG
A
R
LA
A
S
-
SPEAMQS
fig|573235.3.peg.3412
Escherichia coli O26:H11 str. 11368 (11-140/468)
L
LAGIG
G
V
NSNAP
S
VN
DI
GN
TL
Q
LIRQNN
D
ID
RSG
A
NNVGLTALQGL
S
G
I
A
GVFQ
Q
E
KQ
A
Q
R
QK
E
FQ
Q
A
YA
N
A
Y
ASGDR
GA
LR
Q
L
AT
Q
YP
DQI
E
SV
R
K
GM
GFI
DEDQRNSIG
T
LA
AG
A
R
LA
S
S
-
SPEAMQS
fig|550672.3.peg.2067
Escherichia coli B088 (11-140/431)
L
LAGIG
G
V
NSNAP
N
VN
DI
GN
TL
Q
LIRQNN
D
I
ERSG
D
NNVGLTALQGL
S
G
I
A
GVFQ
Q
E
KQ
A
Q
R
QK
E
FQ
Q
A
YA
N
A
Y
ASGDR
GA
LR
Q
L
AT
Q
YP
DQI
E
SV
R
K
GM
GFI
DEDQRNSIG
T
LA
AG
A
R
LA
S
S
-
SPEAMQS
fig|595495.4.peg.85
Escherichia coli KO11 (1-130/452)
M
LAGIG
G
V
NSNAP
S
VN
DI
GN
TL
Q
LIRQNN
D
I
ERSG
A
NNVGLTALQGL
S
G
I
A
GVFQ
Q
E
KQ
A
Q
R
QK
E
FQ
Q
A
YA
N
A
Y
ASGDR
GA
LR
Q
L
AT
Q
YP
DQI
E
SV
R
K
GM
GFI
DE
E
QRNSIG
T
LA
AG
A
H
LA
S
S
-
SPEAMQS
fig|566546.4.peg.2527
Escherichia coli W (1-130/452)
M
LAGIG
G
V
NSNAP
S
VN
DI
GN
TL
Q
LIRQNN
D
I
ERSG
A
NNVGLTALQGL
S
G
I
A
GVFQ
Q
E
KQ
A
Q
R
QK
E
FQ
Q
A
YA
N
A
Y
ASGDR
GA
LR
Q
L
AT
Q
YP
DQI
E
SV
R
K
GM
GFI
DE
E
QRNSIG
T
LA
AG
A
H
LA
S
S
-
SPEAMQS
fig|566546.3.peg.1283
Escherichia coli W (11-140/462)
L
LAGIG
G
V
NSNAP
S
VN
DI
GN
TL
Q
LIRQNN
D
I
ERSG
A
NNVGLTALQGL
S
G
I
A
GVFQ
Q
E
KQ
A
Q
R
QK
E
FQ
Q
A
YA
N
A
Y
ASGDR
GA
LR
Q
L
AT
Q
YP
DQI
E
SV
R
K
GM
GFI
DE
E
QRNSIG
T
LA
AG
A
H
LA
S
S
-
SPEAMQS
fig|749537.3.peg.3512
Escherichia coli MS 115-1 (11-140/462)
L
LAGIG
G
V
NSNAP
S
VN
DI
GN
TL
Q
LIRQNN
D
I
ERSG
A
NNVGLTALQGL
S
G
I
A
GVFQ
Q
E
KQ
A
Q
R
QK
E
FQ
Q
A
YA
N
A
Y
ASGDR
GA
LR
Q
L
AT
Q
YP
DQI
E
SV
R
K
GM
GFI
DEDQRNSIG
T
LA
AG
A
R
LA
S
S
-
SPEAMQS
fig|340184.3.peg.570
Escherichia coli B7A (11-140/462)
L
LAGIG
G
V
NSNAP
S
VN
DI
GN
TL
Q
LIRQNN
D
I
ERSG
A
NNVGLTALQGL
S
G
I
A
GVFQ
Q
E
KQ
A
Q
R
QK
E
FQ
Q
A
YA
N
A
Y
ASGDR
GA
LR
Q
L
AT
Q
YP
DQI
E
SV
R
K
GM
GFI
DEDQRNSIG
T
LA
AG
A
R
LA
A
S
-
SPEAMQS
fig|340184.6.peg.599
Escherichia coli B7A (11-140/462)
L
LAGIG
G
V
NSNAP
S
VN
DI
GN
TL
Q
LIRQNN
D
I
ERSG
A
NNVGLTALQGL
S
G
I
A
GVFQ
Q
E
KQ
A
Q
R
QK
E
FQ
Q
A
YA
N
A
Y
ASGDR
GA
LR
Q
L
AT
Q
YP
DQI
E
SV
R
K
GM
GFI
DEDQRNSIG
T
LA
AG
A
R
LA
A
S
-
SPEAMQS
fig|656443.3.peg.3067
Escherichia coli TA271 (11-140/451)
L
LAGIG
G
V
NSNAP
N
VN
DI
GN
TL
Q
LIRQNN
D
I
ERSG
A
NNVGLTALQGL
S
G
I
A
GVFQ
Q
E
KQ
A
Q
R
QK
E
FQ
Q
A
YA
N
A
Y
ASGDR
GA
LR
Q
L
AT
Q
YP
DQI
E
SV
R
K
GM
GFI
DEDQRNSIG
T
LA
AG
A
R
LA
A
S
-
SPEAMQS
fig|562.371.peg.5221
Escherichia coli 1044A (14-142/378)
LAGIG
G
QNSNAP
K
ASD
V
SE
A
L
A
Y
IRQNNEMERSG
R
NN
I
GL
Q
ALQGL
G
S
VA
QTSQ
A
A
KQQEA
DA
AFQK
E
YA
A
A
I
Q
SGDR
QQ
V
R
D
L
MT
KYP
GQL
E
KI
Q
S
GM
KWA
DEDQRNSIG
T
LA
AG
A
R
LA
A
S
-
SPEAMQS
fig|562.373.peg.3547
Escherichia coli 1125A (14-142/378)
LAGIG
G
QNSNAP
K
ASD
V
SE
A
L
A
Y
IRQNNEMERSG
R
NN
I
GL
Q
ALQGL
G
S
VA
QTSQ
A
A
KQQEA
DA
AFQK
E
YA
A
A
I
Q
SGDR
QQ
V
R
D
L
MT
KYP
GQL
E
KI
Q
S
GM
KWA
DEDQRNSIG
T
LA
AG
A
R
LA
A
S
-
SPEAMQS
fig|562.372.peg.5405
Escherichia coli 1212A (14-142/378)
LAGIG
G
QNSNAP
K
ASD
V
SE
A
L
A
Y
IRQNNEMERSG
R
NN
I
GL
Q
ALQGL
G
S
VA
QTSQ
A
A
KQQEA
DA
AFQK
E
YA
A
A
I
Q
SGDR
QQ
V
R
D
L
MT
KYP
GQL
E
KI
Q
S
GM
KWA
DEDQRNSIG
T
LA
AG
A
R
LA
A
S
-
SPEAMQS
fig|562.374.peg.5935
Escherichia coli 536A (14-142/378)
LAGIG
G
QNSNAP
K
ASD
V
SE
A
L
A
Y
IRQNNEMERSG
R
NN
I
GL
Q
ALQGL
G
S
VA
QTSQ
A
A
KQQEA
DA
AFQK
E
YA
A
A
I
Q
SGDR
QQ
V
R
D
L
MT
KYP
GQL
E
KI
Q
S
GM
KWA
DEDQRNSIG
T
LA
AG
A
R
LA
A
S
-
SPEAMQS
fig|83334.1.peg.3229
Escherichia coli O157:H7 (14-142/378)
LAGIG
G
QNSNAP
K
ASD
V
SE
A
L
A
Y
IRQNNEMERSG
R
NN
I
GL
Q
ALQGL
G
S
VA
QTSQ
A
A
KQQEA
DA
AFQK
E
YA
A
A
I
Q
SGDR
QQ
V
R
D
L
MT
KYP
GQL
E
KI
Q
S
GM
KWA
DEDQRNSIG
T
LA
AG
A
R
LA
A
S
-
SPEAMQS
fig|155864.1.peg.3230
Escherichia coli O157:H7 EDL933 (14-142/378)
LAGIG
G
QNSNAP
K
ASD
V
SE
A
L
A
Y
IRQNNEMERSG
R
NN
I
GL
Q
ALQGL
G
S
VA
QTSQ
A
A
KQQEA
DA
AFQK
E
YA
A
A
I
Q
SGDR
QQ
V
R
D
L
MT
KYP
GQL
E
KI
Q
S
GM
KWA
DEDQRNSIG
T
LA
AG
A
R
LA
A
S
-
SPEAMQS
fig|155864.8.peg.3132
Escherichia coli O157:H7 EDL933 (14-142/378)
LAGIG
G
QNSNAP
K
ASD
V
SE
A
L
A
Y
IRQNNEMERSG
R
NN
I
GL
Q
ALQGL
G
S
VA
QTSQ
A
A
KQQEA
DA
AFQK
E
YA
A
A
I
Q
SGDR
QQ
V
R
D
L
MT
KYP
GQL
E
KI
Q
S
GM
KWA
DEDQRNSIG
T
LA
AG
A
R
LA
A
S
-
SPEAMQS
fig|444454.5.peg.2248
Escherichia coli O157:H7 str. EC4024 (14-142/378)
LAGIG
G
QNSNAP
K
ASD
V
SE
A
L
A
Y
IRQNNEMERSG
R
NN
I
GL
Q
ALQGL
G
S
VA
QTSQ
A
A
KQQEA
DA
AFQK
E
YA
A
A
I
Q
SGDR
QQ
V
R
D
L
MT
KYP
GQL
E
KI
Q
S
GM
KWA
DEDQRNSIG
T
LA
AG
A
R
LA
A
S
-
SPEAMQS
fig|444449.5.peg.1715
Escherichia coli O157:H7 str. EC4042 (14-142/378)
LAGIG
G
QNSNAP
K
ASD
V
SE
A
L
A
Y
IRQNNEMERSG
R
NN
I
GL
Q
ALQGL
G
S
VA
QTSQ
A
A
KQQEA
DA
AFQK
E
YA
A
A
I
Q
SGDR
QQ
V
R
D
L
MT
KYP
GQL
E
KI
Q
S
GM
KWA
DEDQRNSIG
T
LA
AG
A
R
LA
A
S
-
SPEAMQS
fig|444448.5.peg.469
Escherichia coli O157:H7 str. EC4045 (14-142/378)
LAGIG
G
QNSNAP
K
ASD
V
SE
A
L
A
Y
IRQNNEMERSG
R
NN
I
GL
Q
ALQGL
G
S
VA
QTSQ
A
A
KQQEA
DA
AFQK
E
YA
A
A
I
Q
SGDR
QQ
V
R
D
L
MT
KYP
GQL
E
KI
Q
S
GM
KWA
DEDQRNSIG
T
LA
AG
A
R
LA
A
S
-
SPEAMQS
fig|444453.5.peg.1818
Escherichia coli O157:H7 str. EC4076 (14-142/378)
LAGIG
G
QNSNAP
K
ASD
V
SE
A
L
A
Y
IRQNNEMERSG
R
NN
I
GL
Q
ALQGL
G
S
VA
QTSQ
A
A
KQQEA
DA
AFQK
E
YA
A
A
I
Q
SGDR
QQ
V
R
D
L
MT
KYP
GQL
E
KI
Q
S
GM
KWA
DEDQRNSIG
T
LA
AG
A
R
LA
A
S
-
SPEAMQS
fig|444452.5.peg.1382
Escherichia coli O157:H7 str. EC4113 (14-142/378)
LAGIG
G
QNSNAP
K
ASD
V
SE
A
L
A
Y
IRQNNEMERSG
R
NN
I
GL
Q
ALQGL
G
S
VA
QTSQ
A
A
KQQEA
DA
AFQK
E
YA
A
A
I
Q
SGDR
QQ
V
R
D
L
MT
KYP
GQL
E
KI
Q
S
GM
KWA
DEDQRNSIG
T
LA
AG
A
R
LA
A
S
-
SPEAMQS
fig|444450.8.peg.3558
Escherichia coli O157:H7 str. EC4115 (14-142/378)
LAGIG
G
QNSNAP
K
ASD
V
SE
A
L
A
Y
IRQNNEMERSG
R
NN
I
GL
Q
ALQGL
G
S
VA
QTSQ
A
A
KQQEA
DA
AFQK
E
YA
A
A
I
Q
SGDR
QQ
V
R
D
L
MT
KYP
GQL
E
KI
Q
S
GM
KWA
DEDQRNSIG
T
LA
AG
A
R
LA
A
S
-
SPEAMQS
fig|444451.5.peg.563
Escherichia coli O157:H7 str. EC4196 (14-142/378)
LAGIG
G
QNSNAP
K
ASD
V
SE
A
L
A
Y
IRQNNEMERSG
R
NN
I
GL
Q
ALQGL
G
S
VA
QTSQ
A
A
KQQEA
DA
AFQK
E
YA
A
A
I
Q
SGDR
QQ
V
R
D
L
MT
KYP
GQL
E
KI
Q
S
GM
KWA
DEDQRNSIG
T
LA
AG
A
R
LA
A
S
-
SPEAMQS
fig|444447.5.peg.604
Escherichia coli O157:H7 str. EC4206 (14-142/378)
LAGIG
G
QNSNAP
K
ASD
V
SE
A
L
A
Y
IRQNNEMERSG
R
NN
I
GL
Q
ALQGL
G
S
VA
QTSQ
A
A
KQQEA
DA
AFQK
E
YA
A
A
I
Q
SGDR
QQ
V
R
D
L
MT
KYP
GQL
E
KI
Q
S
GM
KWA
DEDQRNSIG
T
LA
AG
A
R
LA
A
S
-
SPEAMQS
fig|478004.5.peg.4052
Escherichia coli O157:H7 str. EC4401 (14-142/378)
LAGIG
G
QNSNAP
K
ASD
V
SE
A
L
A
Y
IRQNNEMERSG
R
NN
I
GL
Q
ALQGL
G
S
VA
QTSQ
A
A
KQQEA
DA
AFQK
E
YA
A
A
I
Q
SGDR
QQ
V
R
D
L
MT
KYP
GQL
E
KI
Q
S
GM
KWA
DEDQRNSIG
T
LA
AG
A
R
LA
A
S
-
SPEAMQS
fig|478005.5.peg.4611
Escherichia coli O157:H7 str. EC4486 (14-142/378)
LAGIG
G
QNSNAP
K
ASD
V
SE
A
L
A
Y
IRQNNEMERSG
R
NN
I
GL
Q
ALQGL
G
S
VA
QTSQ
A
A
KQQEA
DA
AFQK
E
YA
A
A
I
Q
SGDR
QQ
V
R
D
L
MT
KYP
GQL
E
KI
Q
S
GM
KWA
DEDQRNSIG
T
LA
AG
A
R
LA
A
S
-
SPEAMQS
fig|478006.5.peg.3918
Escherichia coli O157:H7 str. EC4501 (14-142/378)
LAGIG
G
QNSNAP
K
ASD
V
SE
A
L
A
Y
IRQNNEMERSG
R
NN
I
GL
Q
ALQGL
G
S
VA
QTSQ
A
A
KQQEA
DA
AFQK
E
YA
A
A
I
Q
SGDR
QQ
V
R
D
L
MT
KYP
GQL
E
KI
Q
S
GM
KWA
DEDQRNSIG
T
LA
AG
A
R
LA
A
S
-
SPEAMQS
fig|478007.5.peg.3363
Escherichia coli O157:H7 str. EC508 (14-142/378)
LAGIG
G
QNSNAP
K
ASD
V
SE
A
L
A
Y
IRQNNEMERSG
R
NN
I
GL
Q
ALQGL
G
S
VA
QTSQ
A
A
KQQEA
DA
AFQK
E
YA
A
A
I
Q
SGDR
QQ
V
R
D
L
MT
KYP
GQL
E
KI
Q
S
GM
KWA
DEDQRNSIG
T
LA
AG
A
R
LA
A
S
-
SPEAMQS
fig|478008.5.peg.2511
Escherichia coli O157:H7 str. EC869 (14-142/378)
LAGIG
G
QNSNAP
K
ASD
V
SE
A
L
A
Y
IRQNNEMERSG
R
NN
I
GL
Q
ALQGL
G
S
VA
QTSQ
A
A
KQQEA
DA
AFQK
E
YA
A
A
I
Q
SGDR
QQ
V
R
D
L
MT
KYP
GQL
E
KI
Q
S
GM
KWA
DEDQRNSIG
T
LA
AG
A
R
LA
A
S
-
SPEAMQS
fig|637388.3.peg.231
Escherichia coli O157:H7 str. FRIK2000 (14-142/378)
LAGIG
G
QNSNAP
K
ASD
V
SE
A
L
A
Y
IRQNNEMERSG
R
NN
I
GL
Q
ALQGL
G
S
VA
QTSQ
A
A
KQQEA
DA
AFQK
E
YA
A
A
I
Q
SGDR
QQ
V
R
D
L
MT
KYP
GQL
E
KI
Q
S
GM
KWA
DEDQRNSIG
T
LA
AG
A
R
LA
A
S
-
SPEAMQS
fig|570506.3.peg.5103
Escherichia coli O157:H7 str. FRIK966 (14-142/378)
LAGIG
G
QNSNAP
K
ASD
V
SE
A
L
A
Y
IRQNNEMERSG
R
NN
I
GL
Q
ALQGL
G
S
VA
QTSQ
A
A
KQQEA
DA
AFQK
E
YA
A
A
I
Q
SGDR
QQ
V
R
D
L
MT
KYP
GQL
E
KI
Q
S
GM
KWA
DEDQRNSIG
T
LA
AG
A
R
LA
A
S
-
SPEAMQS
fig|386585.9.peg.3377
Escherichia coli O157:H7 str. Sakai (14-142/378)
LAGIG
G
QNSNAP
K
ASD
V
SE
A
L
A
Y
IRQNNEMERSG
R
NN
I
GL
Q
ALQGL
G
S
VA
QTSQ
A
A
KQQEA
DA
AFQK
E
YA
A
A
I
Q
SGDR
QQ
V
R
D
L
MT
KYP
GQL
E
KI
Q
S
GM
KWA
DEDQRNSIG
T
LA
AG
A
R
LA
A
S
-
SPEAMQS
fig|544404.4.peg.3361
Escherichia coli O157:H7 str. TW14359 (14-142/378)
LAGIG
G
QNSNAP
K
ASD
V
SE
A
L
A
Y
IRQNNEMERSG
R
NN
I
GL
Q
ALQGL
G
S
VA
QTSQ
A
A
KQQEA
DA
AFQK
E
YA
A
A
I
Q
SGDR
QQ
V
R
D
L
MT
KYP
GQL
E
KI
Q
S
GM
KWA
DEDQRNSIG
T
LA
AG
A
R
LA
A
S
-
SPEAMQS
fig|701177.3.peg.2922
Escherichia coli O55:H7 str. CB9615 (14-142/378)
LAGIG
G
QNSNAP
K
ASD
V
SE
A
L
A
Y
IRQNNEMERSG
R
NN
I
GL
Q
ALQGL
G
S
VA
QTSQ
A
A
KQQEA
DA
AFQK
E
YA
A
A
I
Q
SGDR
QQ
V
R
D
L
MT
KYP
GQL
E
KI
Q
S
GM
KWA
DEDQRNSIG
T
LA
AG
A
R
LA
A
S
-
SPEAMQS
fig|502346.5.peg.4057
Escherichia coli O157:H7 str. TW14588 (14-150/186)
LAGIG
G
QNSNAP
K
ASD
V
SE
A
L
A
Y
IRQNNEMERSG
R
NN
I
GL
Q
ALQGL
G
S
VA
QTSQ
A
A
KQQEA
DA
AFQK
E
YA
A
A
I
Q
SGDR
QQ
V
R
D
L
MT
KYP
GQL
E
KI
Q
S
GM
KWA
DEDQRNSIG
T
LA
AG
A
R
LA
A
S
-
SPEAMQS
WLQN
TPRN
fig|749527.3.peg.752
Escherichia coli MS 21-1 (14-135/483)
LAGIG
T
QN
E
NAP
K
ASDI
NA
TL
G
LIR
E
NNE
L
A
RSG
A
NNVGLTAL
R
GL
A
GVA
DIYK
Q
Q
Q
QQE
R
KA
AFQK
G
YA
D
A
Y
ASGDR
EQ
M
R
N
L
IT
A
F
P
EEF
E
EV
R
K
GM
GYV
D
D
A
QRN
D
F
G
N
LA
LK
A
Q
V
A
S
S
fig|316401.4.peg.377
Escherichia coli ETEC H10407 (14-135/330)
LAGIG
A
QN
E
NAP
K
ASDI
NA
TL
G
LIR
E
NNE
L
A
RSG
A
NNV
A
LT
G
L
R
GL
A
GVA
DIYK
Q
Q
Q
QQE
R
KA
AFQK
G
YA
D
A
Y
ASGDR
EQ
M
R
N
L
IT
A
F
P
EEF
E
EV
R
K
GM
SYV
D
D
A
QR
D
D
Y
G
N
LA
LK
A
Q
V
A
S
S
fig|405955.13.peg.2581
Escherichia coli APEC O1 (14-135/483)
LAGIG
T
QN
E
NAP
K
ASDI
NA
TL
G
LIR
E
NNE
L
A
RSG
A
NNV
A
LT
G
L
R
GL
A
GVA
DIYK
Q
Q
Q
K
QE
R
KA
AFQK
G
YA
D
A
Y
ASGDR
EQ
M
R
N
L
IT
A
F
P
EEF
E
EV
R
K
GM
GYV
D
D
A
QR
D
D
F
G
N
LA
LK
A
Q
V
A
S
S
fig|405955.9.peg.2123
Escherichia coli APEC O1 (14-135/483)
LAGIG
T
QN
E
NAP
K
ASDI
NA
TL
G
LIR
E
NNE
L
A
RSG
A
NNV
A
LT
G
L
R
GL
A
GVA
DIYK
Q
Q
Q
K
QE
R
KA
AFQK
G
YA
D
A
Y
ASGDR
EQ
M
R
N
L
IT
A
F
P
EEF
E
EV
R
K
GM
GYV
D
D
A
QR
D
D
F
G
N
LA
LK
A
Q
V
A
S
S
fig|585035.6.peg.2488
Escherichia coli S88 (14-135/483)
LAGIG
T
QN
E
NAP
K
ASDI
NA
TL
G
LIR
E
NNE
L
A
RSG
A
NNV
A
LT
G
L
R
GL
A
GVA
DIYK
Q
Q
Q
K
QE
R
KA
AFQK
G
YA
D
A
Y
ASGDR
EQ
M
R
N
L
IT
A
F
P
EEF
E
EV
R
K
GM
GYV
D
D
A
QR
D
D
F
G
N
LA
LK
A
Q
V
A
S
S
fig|749545.3.peg.1566
Escherichia coli MS 182-1 (14-135/447)
LAGIG
A
QN
E
NAP
K
ASDI
NA
TL
G
LIR
E
NNE
L
A
RSG
A
NNV
A
LT
G
L
R
GL
A
GVA
DIYK
Q
Q
Q
QQE
R
KA
AFQK
G
YA
D
A
Y
ASGDR
EQ
M
R
N
L
IT
A
F
P
EEF
E
EV
R
K
GM
SYV
D
D
A
QR
D
D
Y
G
N
LA
LK
A
Q
V
A
S
S
fig|670897.3.peg.3670
Escherichia coli 2362-75 (6-120/473)
LG
G
L
PS
M
A
P
QN
D
NAP
R
S
S
-
V
PQ
P
V
Q
Y
Q
Q
Q
-----
-
--
-
P
NVGL
M
ALQGL
R
GVA
EINQ
Q
A
R
QQ
Q
R
KS
E
FQK
A
YA
G
A
F
E
SGDR
NK
M
R
S
L
IS
E
YP
EEF
E
SV
Q
K
GM
GFI
D
D
DQRNSIG
H
LA
TS
A
Q
I
A
S
S
fig|656379.3.peg.2898
Escherichia coli FVEC1302 (14-140/447)
LAGIG
A
QN
E
NAP
K
ASDI
NA
TL
G
LIR
E
NNE
L
A
RSG
A
NNVGLTAL
R
GL
A
GVA
DIYK
Q
E
Q
QQ
K
A
IN
AF
N
K
V
H
A
D
A
W
ASGD
P
SG
L
F
K
F
AQ
E
N
P
AFV
A
QA
Q
Q
AF
SGL
N
E
Q
QRN
DM
G
D
LA
MR
A
N
V
A
L
S
QG
PEA
fig|749545.3.peg.957
Escherichia coli MS 182-1 (14-140/449)
LAGIG
A
QN
E
NAP
K
ASDI
NA
TL
G
LIR
E
NNE
L
A
RSG
A
NNVGLTAL
R
GL
A
GVA
DIYK
Q
E
Q
QQ
K
A
IS
AF
N
K
V
H
A
D
A
W
ASGD
P
SG
L
F
K
F
AQ
E
N
P
AFV
A
QA
Q
Q
AF
SGL
N
E
Q
QRN
DM
G
D
LA
MR
A
N
V
A
L
S
QG
PEA
fig|656440.3.peg.1582
Escherichia coli TA206 (14-140/461)
LAGIG
T
QN
E
NAP
K
ASDI
NA
TL
G
LIR
E
NNE
L
A
RSG
A
NNVGLTAL
R
GL
A
GVA
DIYN
Q
E
Q
QQ
K
A
IS
AF
N
K
V
H
A
D
A
W
ASGD
P
SG
L
F
K
F
AQ
E
N
P
AFV
A
QA
Q
Q
AF
SGL
N
E
Q
QRN
DM
G
D
LA
MR
A
N
V
A
L
S
QG
PEA
fig|331112.3.peg.296
Escherichia coli HS (14-140/461)
LAGIG
A
QN
E
NAP
K
ASDI
NA
TL
G
LIR
E
NNE
L
A
RSG
A
NNVGLTAL
R
GL
A
GVA
DIYK
Q
E
Q
QQ
K
A
IN
AF
N
K
V
H
A
D
A
W
ASGD
P
SG
L
F
K
F
AQ
E
N
P
AFV
A
QA
Q
Q
AF
SGL
ND
Q
QRN
DM
G
D
LA
MR
A
N
V
A
L
S
QG
PEA
fig|331112.6.peg.308
Escherichia coli HS (14-140/461)
LAGIG
A
QN
E
NAP
K
ASDI
NA
TL
G
LIR
E
NNE
L
A
RSG
A
NNVGLTAL
R
GL
A
GVA
DIYK
Q
E
Q
QQ
K
A
IN
AF
N
K
V
H
A
D
A
W
ASGD
P
SG
L
F
K
F
AQ
E
N
P
AFV
A
QA
Q
Q
AF
SGL
ND
Q
QRN
DM
G
D
LA
MR
A
N
V
A
L
S
QG
PEA
fig|749549.3.peg.1539
Escherichia coli MS 198-1 (14-140/461)
LAGIG
T
QN
E
NAP
K
ASDI
NA
TL
G
LIR
E
NNE
L
A
RSG
A
NNVGLTAL
R
GL
A
GVA
DIYN
Q
E
Q
QQ
K
A
IS
AF
N
K
V
H
A
D
A
W
ASGD
P
SG
L
F
K
F
AQ
E
N
P
AFV
A
QA
Q
Q
AF
SGL
N
E
Q
QRN
DM
G
D
LA
MR
A
N
V
A
L
S
QG
PEA
fig|685038.3.peg.957
Escherichia coli O83:H1 str. NRG 857C (14-140/449)
LAGIG
A
QN
E
NAP
K
ASDI
NA
TL
G
LIR
E
NNE
L
A
RSG
A
NNVGLTAL
R
GL
A
GVA
DIYN
Q
E
Q
QQ
K
A
IS
AF
N
K
V
H
A
D
A
W
ASGD
P
SG
L
F
K
F
AQ
E
N
P
AFV
A
QA
Q
Q
AF
SGL
N
E
Q
QRN
DM
G
D
LA
MR
A
N
V
A
L
S
QG
PEA
fig|585055.6.peg.2639
Escherichia coli 55989 (14-140/447)
LAGIG
T
QN
E
NAP
K
ASDI
NA
TL
G
LIR
E
NNE
L
A
RSG
A
NNVGLTAL
R
GL
A
GVA
DIYN
Q
E
Q
QQ
K
A
IS
AF
N
K
V
H
A
D
A
W
ASGD
P
SG
L
F
K
F
AQ
E
N
P
AFV
A
QA
Q
Q
AF
SGL
ND
Q
QRN
DM
G
D
LA
MR
A
N
V
A
L
S
QG
PEA
fig|585055.8.peg.2645
Escherichia coli 55989 (14-140/447)
LAGIG
T
QN
E
NAP
K
ASDI
NA
TL
G
LIR
E
NNE
L
A
RSG
A
NNVGLTAL
R
GL
A
GVA
DIYN
Q
E
Q
QQ
K
A
IS
AF
N
K
V
H
A
D
A
W
ASGD
P
SG
L
F
K
F
AQ
E
N
P
AFV
A
QA
Q
Q
AF
SGL
ND
Q
QRN
DM
G
D
LA
MR
A
N
V
A
L
S
QG
PEA
fig|550677.3.peg.1903
Escherichia coli B354 (14-140/471)
LAGIG
T
QN
E
NAP
K
ASDI
NA
TL
G
LIR
E
NNE
L
A
RSG
A
NNVGLTAL
R
GL
A
GVA
DIYN
Q
E
Q
QQ
K
A
IS
AF
N
K
V
H
A
D
A
W
ASGD
P
SG
L
F
K
F
AQ
E
N
P
AFV
A
QA
Q
Q
AF
SGL
ND
Q
QRN
DM
G
D
LA
MR
A
N
V
A
L
S
QG
PEA
fig|714962.3.peg.2688
Escherichia coli IHE3034 (14-140/449)
LAGIG
A
QN
E
NAP
K
ASDI
NA
TL
G
LIR
E
NNE
L
A
Q
SG
A
NNVGLTAL
R
GL
A
GVA
DIYK
Q
D
Q
QQ
K
A
IN
AF
N
K
V
H
A
D
A
W
ASGD
P
SG
L
F
K
F
AK
E
N
P
AFV
A
QA
Q
Q
AF
SGL
N
E
Q
QRN
DM
G
D
LA
MR
A
N
V
A
L
S
QG
PEA
fig|869729.3.peg.1068
Escherichia coli UM146 (14-140/449)
LAGIG
A
QN
E
NAP
K
ASDI
NA
TL
G
LIR
E
NNE
L
A
Q
SG
A
NNVGLTAL
R
GL
A
GVA
DIYK
Q
D
Q
QQ
K
A
IN
AF
N
K
V
H
A
D
A
W
ASGD
P
SG
L
F
K
F
AK
E
N
P
AFV
A
QA
Q
Q
AF
SGL
N
E
Q
QRN
DM
G
D
LA
MR
A
N
V
A
L
S
QG
PEA
fig|364106.7.peg.2667
Escherichia coli UTI89 (14-140/449)
LAGIG
A
QN
E
NAP
K
ASDI
NA
TL
G
LIR
E
NNE
L
A
Q
SG
A
NNVGLTAL
R
GL
A
GVA
DIYK
Q
D
Q
QQ
K
A
IN
AF
N
K
V
H
A
D
A
W
ASGD
P
SG
L
F
K
F
AK
E
N
P
AFV
A
QA
Q
Q
AF
SGL
N
E
Q
QRN
DM
G
D
LA
MR
A
N
V
A
L
S
QG
PEA
fig|364106.8.peg.2667
Escherichia coli UTI89 (14-140/449)
LAGIG
A
QN
E
NAP
K
ASDI
NA
TL
G
LIR
E
NNE
L
A
Q
SG
A
NNVGLTAL
R
GL
A
GVA
DIYK
Q
D
Q
QQ
K
A
IN
AF
N
K
V
H
A
D
A
W
ASGD
P
SG
L
F
K
F
AK
E
N
P
AFV
A
QA
Q
Q
AF
SGL
N
E
Q
QRN
DM
G
D
LA
MR
A
N
V
A
L
S
QG
PEA
fig|656408.3.peg.2604
Escherichia coli H591 (14-140/471)
LAGIG
T
QN
E
NAP
K
ASDI
NA
TL
G
LIR
E
NNE
L
A
RSG
V
NNVGLTAL
R
GL
A
GVA
DIYN
Q
E
Q
QQ
K
A
IS
AF
N
K
V
H
A
D
A
W
ASGD
P
SG
L
F
K
F
AQ
E
N
P
AFV
A
QA
Q
Q
AF
SGL
ND
Q
QRN
DM
G
D
LA
MR
A
N
V
A
L
S
QG
PEA
fig|216592.1.peg.949
Escherichia coli 042 (6-120/473)
LG
G
L
PS
M
A
P
QN
D
NAP
R
S
S
-
V
PQ
P
V
Q
Y
Q
Q
Q
-----
-
--
-
P
NVGL
M
ALQGL
R
GVA
EINQ
Q
A
R
QQ
Q
R
KA
E
FQK
A
YA
G
A
F
E
SGDR
NK
M
R
S
L
IS
E
YP
EEF
E
SV
Q
K
GM
GFI
D
D
DQRNSIG
H
LA
TS
A
Q
I
A
S
S
fig|216592.3.peg.4122
Escherichia coli 042 (6-120/473)
LG
G
L
PS
M
A
P
QN
D
NAP
R
S
S
-
V
PQ
P
V
Q
Y
Q
Q
Q
-----
-
--
-
P
NVGL
M
ALQGL
R
GVA
EINQ
Q
A
R
QQ
Q
R
KA
E
FQK
A
YA
G
A
F
E
SGDR
NK
M
R
S
L
IS
E
YP
EEF
E
SV
Q
K
GM
GFI
D
D
DQRNSIG
H
LA
TS
A
Q
I
A
S
S
fig|525281.3.peg.2627
Escherichia coli 83972 (6-120/473)
LG
G
L
PS
M
A
P
QN
D
NAP
R
S
S
-
V
PQ
P
V
Q
Y
Q
Q
Q
-----
-
--
-
P
NVGL
M
ALQGL
R
GVA
EINQ
Q
A
R
QQ
Q
R
KA
E
FQK
A
YA
G
A
F
E
SGDR
NK
M
R
S
L
IS
E
YP
EEF
E
SV
Q
K
GM
GFI
D
D
DQRNSIG
H
LA
TS
A
Q
I
A
S
S
fig|655817.3.peg.385
Escherichia coli ABU 83972 (6-120/473)
LG
G
L
PS
M
A
P
QN
D
NAP
R
S
S
-
V
PQ
P
V
Q
Y
Q
Q
Q
-----
-
--
-
P
NVGL
M
ALQGL
R
GVA
EINQ
Q
A
R
QQ
Q
R
KA
E
FQK
A
YA
G
A
F
E
SGDR
NK
M
R
S
L
IS
E
YP
EEF
E
SV
Q
K
GM
GFI
D
D
DQRNSIG
H
LA
TS
A
Q
I
A
S
S
Consen1
Primary consensus
LG
LAGIG
qNsNAP
asDi
tL
lIRqNNemerSG
NNvGLtALqGL
gvA
q
kQqea
aFqk
yA
A
aSGDr
lr
l
kyP
e
q
gm
dedQRNsiG
LA
A
lA
S
-
sPEAMQS
TPRN
Consen2
Secondary consensus
v
e
vn
v
a
y
e
d
a
-
i
q
r
si
a
q
a
r
e
nq
h
q
p
f
f
n
a
r
af
nd
dm
v
qg
Consensus 1
(when a gap)
Conservative difference
Consensus 2
(when a gap)
Nonconservative diff.
Other character