┌─ Escherichia coli APEC O1 (6)  
                          ┌┴─────── Escherichia coli 83972 (6)  
                         ┌┴─────── Escherichia coli ED1a (1)  
                  ┌──────┴────────────── Escherichia coli 536 (3)  
           ┌──────┴┬─────── Escherichia coli M605 (1)  
          ┌┤       └─ Escherichia coli 2362-75 (4)  
   ┌──────┤└─ Escherichia coli WV_060327   
┌──┤      └─────── Escherichia coli MS 21-1   
│  └─────── Escherichia coli SMS-3-5   
┤          ┌─ Escherichia coli TA143   
│   ┌──────┴─────── Escherichia coli FVEC1302 (2)  
│   │       ┌─ Escherichia coli IAI39 (1)  
└───┤      ┌┴─────── Escherichia coli H299   
    │      │        ┌─ fig|1040638.4.peg.5590 O104:H4 str. LB226692 (38)  
    └──────┤       ┌┴─────── Escherichia coli O111:H- str. 11128   
           │      ┌┴─────── Escherichia coli 53638 (1)  
           └──────┤      ┌─ Escherichia coli 1044A (26)  
                  └──────┤       ┌─ Escherichia coli ATCC 8739 (4)  
                         └┬──────┴────────────── Escherichia coli K12 (8)  
                          └──────┬─────── Escherichia coli 042 (1)  
                                 └─────────────┬───────────────────── Escherichia coli M718 (3)  
                                               └┬─────── Escherichia coli TA280   
                                                └─ Escherichia coli B354   
  

  
Carbamoyl-phosphate synthase large chain (EC 6.3.5.5)
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