fig|1040638.4.peg.5198
Escherichia coli O104:H4 str. LB226692
M
IRTDDERTH
H
YHYDS
L
HRLVHY
I
R
I
QY
E
EPLVESRYLYDPLGRR
T
G
KRVWRRERDLTGWMSLSRKP
E
VTWYGWDGDRLTT
V
Q
T
D
T
TRIQT
V
YQPGSF
A
PLIR
I
ET
D
N
GE
R
E
K
A
QRRSLA
E
K
LQQ
E
G
S
EDG
HG
VVFP
AE
LV
RL
LDRLE
E
EI
R
ADRVS
S
ESR
A
WLA
Q
CGLTVEQ
LA
R
Q
VE
P
E
YTPARK
A
HLYHCDHRGLPLALIS
E
D
G
N
TAW
S
AEYDEWGN
Q
LNEENPH
HVY
Q
PY
RLPGQQ
H
DEESGLYYNRHRYYDPLQGRYITQDP
M
GLKGGWNLY
Q
YPLNP
L
QQ
IDP
M
GL
LQ
T
W
D
DA
R
SGACT
G
G
V
CG
V
LS
RI
IGP
S
KFDS
TA
D
A
A
L
DAL
KET
Q
N
R
S
L
C
N
D
M
EY
S
G
IV
CKD
TN
G
K
YF
ASK
A
ETD
N
L
RK
E
SYPL
-
K
R
KCP
T
GT
D
RV
A
AYHTHG
--
ADSHG
-------
DY
V
DE
F
-
FSS
S
D
KN
LV
R
SKDNN
L
E
---
-
A
FYL
A
TP
D
G
R
F
E
A
L
NNKG
EY
I
L
S
EI
G
fig|331111.12.peg.843
Escherichia coli E24377A (970-1412/1429)
VIRTDDERTH
H
YHYDS
L
HRLVHY
I
R
I
QY
E
EPLVESRYLYDPLGRR
T
G
KRVWRRERDLTGWMSLSRKP
E
VTWYGWDGDRLTT
V
Q
T
D
T
TRIQT
V
YQPGSF
A
PLIR
I
ET
D
N
GE
R
E
K
A
QRRSLA
E
K
LQQ
E
G
S
EDG
HG
VVFP
AE
LV
RL
LDRLE
E
EI
R
ADRVS
S
ESR
A
WLA
Q
CGLTVEQ
LA
R
Q
VE
P
E
YTPARK
A
HLYHCDHRGLPLALIS
E
D
G
N
TAW
S
AEYDEWGN
Q
LNEENPH
HVY
Q
PY
RLPGQQ
H
DEESGLYYNRHRYYDPLQGRYITQDP
M
GLKGGWNLY
Q
YPLNP
L
QQ
IDP
M
GL
LQ
T
W
D
DA
R
SGACT
G
G
V
CG
V
LS
RI
IGP
S
KFDS
TA
D
A
A
L
DAL
KET
Q
N
R
S
L
C
N
D
M
EY
S
G
IV
CKD
TN
G
K
YF
ASK
A
ETD
N
L
RK
E
SYPL
-
K
R
KCP
T
GT
D
RV
A
AYHTHG
--
ADSHG
-------
DY
V
DE
F
-
FSS
S
D
KN
LV
R
SKDNN
L
E
---
-
A
FYL
A
TP
D
G
R
F
E
A
L
NNKG
EY
I
F
fig|331111.3.peg.3071
Escherichia coli E24377A (970-1412/1429)
VIRTDDERTH
H
YHYDS
L
HRLVHY
I
R
I
QY
E
EPLVESRYLYDPLGRR
T
G
KRVWRRERDLTGWMSLSRKP
E
VTWYGWDGDRLTT
V
Q
T
D
T
TRIQT
V
YQPGSF
A
PLIR
I
ET
D
N
GE
R
E
K
A
QRRSLA
E
K
LQQ
E
G
S
EDG
HG
VVFP
AE
LV
RL
LDRLE
E
EI
R
ADRVS
S
ESR
A
WLA
Q
CGLTVEQ
LA
R
Q
VE
P
E
YTPARK
A
HLYHCDHRGLPLALIS
E
D
G
N
TAW
S
AEYDEWGN
Q
LNEENPH
HVY
Q
PY
RLPGQQ
H
DEESGLYYNRHRYYDPLQGRYITQDP
M
GLKGGWNLY
Q
YPLNP
L
QQ
IDP
M
GL
LQ
T
W
D
DA
R
SGACT
G
G
V
CG
V
LS
RI
IGP
S
KFDS
TA
D
A
A
L
DAL
KET
Q
N
R
S
L
C
N
D
M
EY
S
G
IV
CKD
TN
G
K
YF
ASK
A
ETD
N
L
RK
E
SYPL
-
K
R
KCP
T
GT
D
RV
A
AYHTHG
--
ADSHG
-------
DY
V
DE
F
-
FSS
S
D
KN
LV
R
SKDNN
L
E
---
-
A
FYL
A
TP
D
G
R
F
E
A
L
NNKG
EY
I
F
fig|679207.4.peg.1730
Escherichia coli MS 107-1 (970-1412/1429)
VIRTDDERTH
H
YHYDS
L
HRLVHY
I
R
I
QY
E
EPLVESRYLYDPLGRR
T
G
KRVWRRERDLTGWMSLSRKP
E
VTWYGWDGDRLTT
V
Q
T
D
T
TRIQT
V
YQPGSF
A
PLIR
I
ET
D
N
GE
R
E
K
A
QRRSLA
E
K
LQQ
E
G
S
EDG
HG
VVFP
AE
LV
RL
LDRLE
E
EI
R
ADRVS
S
ESR
A
WLA
Q
CGLTVEQ
LA
R
Q
VE
P
E
YTPARK
A
HLYHCDHRGLPLALIS
E
D
G
N
TAW
S
AEYDEWGN
Q
LNEENPH
HVY
Q
PY
RLPGQQ
H
DEESGLYYNRHRYYDPLQGRYITQDP
M
GLKGGWNLY
Q
YPLNP
L
QQ
IDP
M
GL
LQ
T
W
D
DA
R
SGACT
G
G
V
CG
V
LS
RI
IGP
S
KFDS
TA
D
A
A
L
DAL
KET
Q
N
R
S
L
C
N
D
M
EY
S
G
IV
CKD
TN
G
K
YF
ASK
A
ETD
N
L
RK
E
SYPL
-
K
R
KCP
T
GT
D
RV
A
AYHTHG
--
ADSHG
-------
DY
V
DE
F
-
FSS
S
D
KN
LV
R
SKDNN
L
E
---
-
A
FYL
A
TP
D
G
R
F
E
A
L
NNKG
EY
I
F
fig|409438.11.peg.651
Escherichia coli SE11 (970-1412/1429)
VIRTDDERTH
H
YHYDS
L
HRLVHY
I
R
I
QY
E
EPLVESRYLYDPLGRR
T
G
KRVWRRERDLTGWMSLSRKP
E
VTWYGWDGDRLTT
V
Q
T
D
T
TRIQT
V
YQPGSF
A
PLIR
I
ET
D
N
GE
R
E
K
A
QRRSLA
E
K
LQQ
E
G
S
EDG
HG
VVFP
AE
LV
RL
LDRLE
E
EI
R
ADRVS
S
ESR
A
WLA
Q
CGLTVEQ
LA
R
Q
VE
P
E
YTPARK
A
HLYHCDHRGLPLALIS
E
D
G
N
TAW
S
AEYDEWGN
Q
LNEENPH
HVY
Q
PY
RLPGQQ
H
DEESGLYYNRHRYYDPLQGRYITQDP
M
GLKGGWNLY
Q
YPLNP
L
QQ
IDP
M
GL
LQ
T
W
D
DA
R
SGACT
G
G
V
CG
V
LS
RI
IGP
S
KFDS
TA
D
A
A
L
DAL
KET
Q
N
R
S
L
C
N
D
M
EY
S
G
IV
CKD
TN
G
K
YF
ASK
A
ETD
N
L
RK
E
SYPL
-
K
R
KCP
T
GT
D
RV
A
AYHTHG
--
ADSHG
-------
DY
V
DE
F
-
FSS
S
D
KN
LV
R
SKDNN
L
E
---
-
A
FYL
A
TP
D
G
R
F
E
A
L
NNKG
EY
I
F
fig|585055.6.peg.522
Escherichia coli 55989 (970-1412/1422)
VIRTDDERTH
H
YHYDS
L
HRLVHY
I
R
I
QY
E
EPLVESRYLYDPLGRR
T
G
KRVWRRERDLTGWMSLSRKP
E
VTWYGWDGDRLTT
V
Q
T
D
T
TRIQT
V
YQPGSF
A
PLIR
I
ET
D
N
GE
R
E
K
A
QRRSLA
E
K
LQQ
E
G
S
EDG
HG
VVFP
AE
LV
RL
LDRLE
E
EI
R
ADRVS
S
ESR
A
WLA
Q
CGLTVEQ
LA
R
Q
VE
P
E
YTPARK
A
HLYHCDHRGLPLALIS
E
D
G
N
TAW
S
AEYDEWGN
Q
LNEENPH
HVY
Q
PY
RLPGQQ
H
DEESGLYYNRHRYYDPLQGRYITQDP
M
GLKGGWNLY
Q
YPLNP
L
QQ
IDP
M
GL
LQ
T
W
D
DA
R
SGACT
G
G
V
CG
V
LS
RI
IGP
S
KFDS
TA
D
A
A
L
DAL
KET
Q
N
R
S
L
C
N
D
M
EY
S
G
IV
CKD
TN
G
K
YF
ASK
A
ETD
N
L
RK
E
SYPL
-
K
R
KCP
T
GT
D
RV
A
AYHTHG
--
ADSHG
-------
DY
V
DE
F
-
FSS
S
D
KN
LV
R
SKDNN
L
E
---
-
A
FYL
A
TP
D
G
R
F
E
A
L
NNKG
EY
I
F
fig|585055.8.peg.523
Escherichia coli 55989 (970-1412/1422)
VIRTDDERTH
H
YHYDS
L
HRLVHY
I
R
I
QY
E
EPLVESRYLYDPLGRR
T
G
KRVWRRERDLTGWMSLSRKP
E
VTWYGWDGDRLTT
V
Q
T
D
T
TRIQT
V
YQPGSF
A
PLIR
I
ET
D
N
GE
R
E
K
A
QRRSLA
E
K
LQQ
E
G
S
EDG
HG
VVFP
AE
LV
RL
LDRLE
E
EI
R
ADRVS
S
ESR
A
WLA
Q
CGLTVEQ
LA
R
Q
VE
P
E
YTPARK
A
HLYHCDHRGLPLALIS
E
D
G
N
TAW
S
AEYDEWGN
Q
LNEENPH
HVY
Q
PY
RLPGQQ
H
DEESGLYYNRHRYYDPLQGRYITQDP
M
GLKGGWNLY
Q
YPLNP
L
QQ
IDP
M
GL
LQ
T
W
D
DA
R
SGACT
G
G
V
CG
V
LS
RI
IGP
S
KFDS
TA
D
A
A
L
DAL
KET
Q
N
R
S
L
C
N
D
M
EY
S
G
IV
CKD
TN
G
K
YF
ASK
A
ETD
N
L
RK
E
SYPL
-
K
R
KCP
T
GT
D
RV
A
AYHTHG
--
ADSHG
-------
DY
V
DE
F
-
FSS
S
D
KN
LV
R
SKDNN
L
E
---
-
A
FYL
A
TP
D
G
R
F
E
A
L
NNKG
EY
I
F
fig|595495.4.peg.4229
Escherichia coli KO11 (69-511/528)
VIRTDDERTH
H
YHYDS
L
HRLVHY
I
R
I
QY
E
EPLVESRYLYDPLGRR
T
G
KRVWRRERDLTGWMSLSRKP
E
VTWYGWDGDRLTT
V
Q
T
D
T
TRIQT
V
YQPGSF
A
PLIR
I
ET
D
N
GE
R
E
K
A
QRRSLA
E
K
LQQ
E
G
S
EDG
HG
VVFP
AE
LV
RL
LDRLE
E
EI
R
ADRVS
S
ESR
A
WLA
Q
CGLTVEQ
LA
R
Q
VE
P
E
YTPARK
A
HLYHCDHRGLPLALIS
E
D
G
N
TAW
S
AEYDEWGN
Q
LNEENPH
HVY
Q
PY
RLPGQQ
H
DEESGLYYNRHRYYDPLQGRYITQDP
M
GLKGGWNLY
Q
YPLNP
L
QQ
IDP
I
GL
LQ
T
W
D
DA
R
SGACT
G
G
V
CG
V
LS
RI
IGP
S
KFDS
TA
D
A
A
L
DAL
KET
Q
N
R
S
L
C
N
D
M
EY
S
G
IV
CKD
TN
G
K
YF
ASK
A
ETD
N
L
RK
E
SYPL
-
K
R
KCP
T
GT
D
RV
A
AYHTHG
--
ADSHG
-------
DY
V
DE
F
-
FSS
S
D
KN
LV
R
SKDNN
L
E
---
-
A
FYL
A
TP
D
G
R
F
E
A
L
NNKG
EY
I
F
fig|585034.4.peg.498
Escherichia coli IAI1 (970-1412/1429)
VIRTDDERTH
H
YHYDS
L
HRLVHY
I
R
I
QY
E
EPLVESRYLYDPLGRR
M
AKRVWRRERDLTGWMSLSRKP
E
M
TWYGWDGDRLTT
V
Q
T
D
T
TRIQT
V
YQPGSF
A
PLIR
I
ET
D
N
GE
R
E
K
A
QRRSLA
E
K
LQQ
E
G
S
EDG
HG
VVFP
AE
LV
RL
LDRLE
E
EI
R
ADRVS
S
ESR
A
WLA
Q
CGLTVEQ
LA
R
Q
VE
P
E
YTPARK
A
HLYHCDHRGLPLALIS
E
D
G
N
TAW
S
AEYDEWGN
Q
LNEENPH
HVY
Q
PY
RLPGQQ
H
DEESGLYYNRHRYYDPLQGRYITQDP
M
GLKGGWNLY
Q
YPLNP
L
QQ
IDP
M
GL
LQ
T
W
D
DA
R
SGACT
G
G
V
CG
V
LS
RI
IGP
S
KFDS
TA
D
A
A
L
DAL
KET
Q
N
R
S
L
C
N
D
M
EY
S
G
IV
CKD
TN
G
K
YF
ASK
A
ETD
N
L
RK
E
SYPL
-
K
R
KCP
T
GT
D
RV
A
AYHTHG
--
ADSHG
-------
DY
V
DE
F
-
FSS
S
D
KN
LV
R
SKDNN
L
E
---
-
A
FYL
A
TP
D
G
R
F
E
A
L
NNKG
EY
I
F
fig|585034.5.peg.497
Escherichia coli IAI1 (970-1412/1429)
VIRTDDERTH
H
YHYDS
L
HRLVHY
I
R
I
QY
E
EPLVESRYLYDPLGRR
M
AKRVWRRERDLTGWMSLSRKP
E
M
TWYGWDGDRLTT
V
Q
T
D
T
TRIQT
V
YQPGSF
A
PLIR
I
ET
D
N
GE
R
E
K
A
QRRSLA
E
K
LQQ
E
G
S
EDG
HG
VVFP
AE
LV
RL
LDRLE
E
EI
R
ADRVS
S
ESR
A
WLA
Q
CGLTVEQ
LA
R
Q
VE
P
E
YTPARK
A
HLYHCDHRGLPLALIS
E
D
G
N
TAW
S
AEYDEWGN
Q
LNEENPH
HVY
Q
PY
RLPGQQ
H
DEESGLYYNRHRYYDPLQGRYITQDP
M
GLKGGWNLY
Q
YPLNP
L
QQ
IDP
M
GL
LQ
T
W
D
DA
R
SGACT
G
G
V
CG
V
LS
RI
IGP
S
KFDS
TA
D
A
A
L
DAL
KET
Q
N
R
S
L
C
N
D
M
EY
S
G
IV
CKD
TN
G
K
YF
ASK
A
ETD
N
L
RK
E
SYPL
-
K
R
KCP
T
GT
D
RV
A
AYHTHG
--
ADSHG
-------
DY
V
DE
F
-
FSS
S
D
KN
LV
R
SKDNN
L
E
---
-
A
FYL
A
TP
D
G
R
F
E
A
L
NNKG
EY
I
F
fig|566546.4.peg.576
Escherichia coli W (329-771/788)
VIRTDDERTH
H
YHYDS
L
HRLVHY
I
R
I
QY
E
EPLVESRYLYDPLGRR
T
G
KRVWRRERDLTGWMSLSRKP
E
VTWYGWDGDRLTT
V
Q
T
D
T
TRIQT
V
YQPGSF
A
PLIR
I
ET
D
N
GE
R
E
K
A
QRRSLA
E
K
LQQ
E
G
S
EDG
HG
VVFP
AE
LV
RL
LDRLE
E
EI
R
ADRVS
S
ESR
A
WLA
Q
CGLTVEQ
LA
R
Q
VE
P
E
YTPARK
A
HLYHCDHRGLPLALIS
E
D
G
N
TAW
S
AEYDEWGN
Q
LNEENPH
HVY
Q
PY
RLPGQQ
H
DEESGLYYNRHRYYDPLQGRYITQDP
M
GLKGGWNLY
Q
YPLNP
L
QQ
IDP
I
GL
LQ
T
W
D
DA
R
SGACT
G
G
V
CG
V
LS
RI
IGP
S
KFDS
TA
D
A
A
L
DAL
KET
Q
N
R
S
L
C
N
D
M
EY
S
G
IV
CKD
TN
G
K
YF
ASK
A
ETD
N
L
RK
E
SYPL
-
K
R
KCP
T
GT
D
RV
A
AYHTHG
--
ADSHG
-------
DY
V
DE
F
-
FSS
S
D
KN
LV
R
SKDNN
L
E
---
-
A
FYL
A
TP
D
G
R
F
E
A
L
NNKG
EY
I
F
fig|344610.3.peg.1505
Escherichia coli 53638 (967-1409/1426)
VIRTDDERTH
H
YHYDSQHRLV
F
YTR
I
Q
H
G
EPLVESRYLYDPLGRR
T
G
KRVWRRERDLTGWMSLSRKP
E
VTWYGWDGDRLTT
V
Q
T
D
T
TRIQT
V
YQPGSF
A
PLIR
I
ET
D
N
GE
R
E
K
A
QRRSLA
E
K
LQQ
E
G
S
EDG
HG
VVFP
AE
LV
RL
LDRLE
E
EI
R
ADRVS
S
ESR
A
WLA
Q
CGLTVEQ
LA
R
Q
VE
P
E
YTPARK
A
HLYHCDHRGLPLALIS
E
D
G
N
TAW
S
AEYDEWGN
Q
LNEENPH
HVY
Q
PY
RLPGQQ
H
DEESGLYYNRHRYYDPLQGRYITQDP
M
GLKGGWNLY
Q
YPLNP
L
QQ
IDP
M
GL
LQ
T
W
D
DA
R
SGACT
G
G
V
CG
V
LS
RI
IGP
S
KFDS
TA
D
A
A
L
DAL
KET
Q
N
R
S
L
C
N
D
M
EY
S
G
IV
CKD
TN
G
K
YF
ASK
A
ETD
N
L
RK
E
SYPL
-
K
R
KCP
T
GT
D
RV
A
AYHTHG
--
ADSHG
-------
DY
V
DE
F
-
FSS
S
D
KN
LV
R
SKDNN
L
E
---
-
A
FYL
A
TP
D
G
R
F
E
A
L
NNKG
EY
I
F
fig|344610.7.peg.1175
Escherichia coli 53638 (967-1409/1426)
VIRTDDERTH
H
YHYDSQHRLV
F
YTR
I
Q
H
G
EPLVESRYLYDPLGRR
T
G
KRVWRRERDLTGWMSLSRKP
E
VTWYGWDGDRLTT
V
Q
T
D
T
TRIQT
V
YQPGSF
A
PLIR
I
ET
D
N
GE
R
E
K
A
QRRSLA
E
K
LQQ
E
G
S
EDG
HG
VVFP
AE
LV
RL
LDRLE
E
EI
R
ADRVS
S
ESR
A
WLA
Q
CGLTVEQ
LA
R
Q
VE
P
E
YTPARK
A
HLYHCDHRGLPLALIS
E
D
G
N
TAW
S
AEYDEWGN
Q
LNEENPH
HVY
Q
PY
RLPGQQ
H
DEESGLYYNRHRYYDPLQGRYITQDP
M
GLKGGWNLY
Q
YPLNP
L
QQ
IDP
M
GL
LQ
T
W
D
DA
R
SGACT
G
G
V
CG
V
LS
RI
IGP
S
KFDS
TA
D
A
A
L
DAL
KET
Q
N
R
S
L
C
N
D
M
EY
S
G
IV
CKD
TN
G
K
YF
ASK
A
ETD
N
L
RK
E
SYPL
-
K
R
KCP
T
GT
D
RV
A
AYHTHG
--
ADSHG
-------
DY
V
DE
F
-
FSS
S
D
KN
LV
R
SKDNN
L
E
---
-
A
FYL
A
TP
D
G
R
F
E
A
L
NNKG
EY
I
F
fig|358709.5.peg.2056
Escherichia coli 101-1 (967-1409/1426)
VIRTDDERTH
H
YHYDSQHRLV
F
YTR
I
Q
H
G
EPLVESRYLYDPLGRR
M
AKRVWRRERDLTGWMSLSRKP
E
VTWYGWDGDRLTT
V
Q
T
D
T
TRIQT
V
Y
E
PGSFTPLIRVET
E
N
GE
R
E
K
A
QRRSLA
E
T
LQQ
E
G
S
E
N
G
HG
VVFP
AE
LV
RL
LDRLE
E
EI
R
ADRVS
S
ESR
A
WLA
Q
CGLTVEQ
LA
R
Q
VE
P
E
YTPARK
A
HLYHCDHRGLPLALIS
E
D
G
N
TAW
S
AEYDEWGN
Q
LNEENPH
HVY
Q
PY
RLPGQQ
H
DEESGLYYNRHRYYDPLQGRYITQDP
M
GLKGGWNLY
Q
YPLNP
L
QQ
IDP
M
GL
LQ
T
W
D
DA
R
SGACT
G
G
V
CG
V
LS
RI
IGP
S
KFDS
TA
D
A
A
L
DAL
KET
Q
N
R
S
L
C
N
D
M
EY
S
G
IV
CKD
TN
G
K
YF
ASK
A
ETD
N
L
RK
E
SYPL
-
K
R
KCP
T
GT
D
RV
A
AYHTHG
--
ADSHG
-------
DY
V
DE
F
-
FSS
S
D
KN
LV
R
SKDNN
L
E
---
-
A
FYL
A
TP
D
G
R
F
E
A
L
NNKG
EY
I
F
fig|595496.3.peg.420
Escherichia coli BW2952 (967-1409/1426)
VIRTDDERTH
H
YHYDSQHRLV
F
YTR
I
Q
H
G
EPLVESRYLYDPLGRR
M
AKRVWRRERDLTGWMSLSRKP
E
VTWYGWDGDRLTT
V
Q
T
D
T
TRIQT
V
Y
E
PGSFTPLIRVET
E
N
GE
R
E
K
A
QRRSLA
E
T
LQQ
E
G
S
E
N
G
HG
VVFP
AE
LV
RL
LDRLE
E
EI
R
ADRVS
S
ESR
A
WLA
Q
CGLTVEQ
LA
R
Q
VE
P
E
YTPARK
A
HLYHCDHRGLPLALIS
E
D
G
N
TAW
S
AEYDEWGN
Q
LNEENPH
HVY
Q
PY
RLPGQQ
H
DEESGLYYNRHRYYDPLQGRYITQDP
M
GLKGGWNLY
Q
YPLNP
L
QQ
IDP
M
GL
LQ
T
W
D
DA
R
SGACT
G
G
V
CG
V
LS
RI
IGP
S
KFDS
TA
D
A
A
L
DAL
KET
Q
N
R
S
L
C
N
D
M
EY
S
G
IV
CKD
TN
G
K
YF
ASK
A
ETD
N
L
RK
E
SYPL
-
K
R
KCP
T
GT
D
RV
A
AYHTHG
--
ADSHG
-------
DY
V
DE
F
-
FSS
S
D
KN
LV
R
SKDNN
L
E
---
-
A
FYL
A
TP
D
G
R
F
E
A
L
NNKG
EY
I
F
fig|536056.3.peg.3290
Escherichia coli DH1 (967-1409/1426)
VIRTDDERTH
H
YHYDSQHRLV
F
YTR
I
Q
H
G
EPLVESRYLYDPLGRR
M
AKRVWRRERDLTGWMSLSRKP
E
VTWYGWDGDRLTT
V
Q
T
D
T
TRIQT
V
Y
E
PGSFTPLIRVET
E
N
GE
R
E
K
A
QRRSLA
E
T
LQQ
E
G
S
E
N
G
HG
VVFP
AE
LV
RL
LDRLE
E
EI
R
ADRVS
S
ESR
A
WLA
Q
CGLTVEQ
LA
R
Q
VE
P
E
YTPARK
A
HLYHCDHRGLPLALIS
E
D
G
N
TAW
S
AEYDEWGN
Q
LNEENPH
HVY
Q
PY
RLPGQQ
H
DEESGLYYNRHRYYDPLQGRYITQDP
M
GLKGGWNLY
Q
YPLNP
L
QQ
IDP
M
GL
LQ
T
W
D
DA
R
SGACT
G
G
V
CG
V
LS
RI
IGP
S
KFDS
TA
D
A
A
L
DAL
KET
Q
N
R
S
L
C
N
D
M
EY
S
G
IV
CKD
TN
G
K
YF
ASK
A
ETD
N
L
RK
E
SYPL
-
K
R
KCP
T
GT
D
RV
A
AYHTHG
--
ADSHG
-------
DY
V
DE
F
-
FSS
S
D
KN
LV
R
SKDNN
L
E
---
-
A
FYL
A
TP
D
G
R
F
E
A
L
NNKG
EY
I
F
fig|83333.1.peg.493
Escherichia coli K12 (967-1409/1426)
VIRTDDERTH
H
YHYDSQHRLV
F
YTR
I
Q
H
G
EPLVESRYLYDPLGRR
M
AKRVWRRERDLTGWMSLSRKP
E
VTWYGWDGDRLTT
V
Q
T
D
T
TRIQT
V
Y
E
PGSFTPLIRVET
E
N
GE
R
E
K
A
QRRSLA
E
T
LQQ
E
G
S
E
N
G
HG
VVFP
AE
LV
RL
LDRLE
E
EI
R
ADRVS
S
ESR
A
WLA
Q
CGLTVEQ
LA
R
Q
VE
P
E
YTPARK
A
HLYHCDHRGLPLALIS
E
D
G
N
TAW
S
AEYDEWGN
Q
LNEENPH
HVY
Q
PY
RLPGQQ
H
DEESGLYYNRHRYYDPLQGRYITQDP
M
GLKGGWNLY
Q
YPLNP
L
QQ
IDP
M
GL
LQ
T
W
D
DA
R
SGACT
G
G
V
CG
V
LS
RI
IGP
S
KFDS
TA
D
A
A
L
DAL
KET
Q
N
R
S
L
C
N
D
M
EY
S
G
IV
CKD
TN
G
K
YF
ASK
A
ETD
N
L
RK
E
SYPL
-
K
R
KCP
T
GT
D
RV
A
AYHTHG
--
ADSHG
-------
DY
V
DE
F
-
FSS
S
D
KN
LV
R
SKDNN
L
E
---
-
A
FYL
A
TP
D
G
R
F
E
A
L
NNKG
EY
I
F
fig|316407.3.peg.482
Escherichia coli W3110 (967-1409/1426)
VIRTDDERTH
H
YHYDSQHRLV
F
YTR
I
Q
H
G
EPLVESRYLYDPLGRR
M
AKRVWRRERDLTGWMSLSRKP
E
VTWYGWDGDRLTT
V
Q
T
D
T
TRIQT
V
Y
E
PGSFTPLIRVET
E
N
GE
R
E
K
A
QRRSLA
E
T
LQQ
E
G
S
E
N
G
HG
VVFP
AE
LV
RL
LDRLE
E
EI
R
ADRVS
S
ESR
A
WLA
Q
CGLTVEQ
LA
R
Q
VE
P
E
YTPARK
A
HLYHCDHRGLPLALIS
E
D
G
N
TAW
S
AEYDEWGN
Q
LNEENPH
HVY
Q
PY
RLPGQQ
H
DEESGLYYNRHRYYDPLQGRYITQDP
M
GLKGGWNLY
Q
YPLNP
L
QQ
IDP
M
GL
LQ
T
W
D
DA
R
SGACT
G
G
V
CG
V
LS
RI
IGP
S
KFDS
TA
D
A
A
L
DAL
KET
Q
N
R
S
L
C
N
D
M
EY
S
G
IV
CKD
TN
G
K
YF
ASK
A
ETD
N
L
RK
E
SYPL
-
K
R
KCP
T
GT
D
RV
A
AYHTHG
--
ADSHG
-------
DY
V
DE
F
-
FSS
S
D
KN
LV
R
SKDNN
L
E
---
-
A
FYL
A
TP
D
G
R
F
E
A
L
NNKG
EY
I
F
fig|316385.5.peg.453
Escherichia coli str. K-12 substr. DH10B (967-1409/1426)
VIRTDDERTH
H
YHYDSQHRLV
F
YTR
I
Q
H
G
EPLVESRYLYDPLGRR
M
AKRVWRRERDLTGWMSLSRKP
E
VTWYGWDGDRLTT
V
Q
T
D
T
TRIQT
V
Y
E
PGSFTPLIRVET
E
N
GE
R
E
K
A
QRRSLA
E
T
LQQ
E
G
S
E
N
G
HG
VVFP
AE
LV
RL
LDRLE
E
EI
R
ADRVS
S
ESR
A
WLA
Q
CGLTVEQ
LA
R
Q
VE
P
E
YTPARK
A
HLYHCDHRGLPLALIS
E
D
G
N
TAW
S
AEYDEWGN
Q
LNEENPH
HVY
Q
PY
RLPGQQ
H
DEESGLYYNRHRYYDPLQGRYITQDP
M
GLKGGWNLY
Q
YPLNP
L
QQ
IDP
M
GL
LQ
T
W
D
DA
R
SGACT
G
G
V
CG
V
LS
RI
IGP
S
KFDS
TA
D
A
A
L
DAL
KET
Q
N
R
S
L
C
N
D
M
EY
S
G
IV
CKD
TN
G
K
YF
ASK
A
ETD
N
L
RK
E
SYPL
-
K
R
KCP
T
GT
D
RV
A
AYHTHG
--
ADSHG
-------
DY
V
DE
F
-
FSS
S
D
KN
LV
R
SKDNN
L
E
---
-
A
FYL
A
TP
D
G
R
F
E
A
L
NNKG
EY
I
F
fig|316385.7.peg.460
Escherichia coli str. K-12 substr. DH10B (967-1409/1426)
VIRTDDERTH
H
YHYDSQHRLV
F
YTR
I
Q
H
G
EPLVESRYLYDPLGRR
M
AKRVWRRERDLTGWMSLSRKP
E
VTWYGWDGDRLTT
V
Q
T
D
T
TRIQT
V
Y
E
PGSFTPLIRVET
E
N
GE
R
E
K
A
QRRSLA
E
T
LQQ
E
G
S
E
N
G
HG
VVFP
AE
LV
RL
LDRLE
E
EI
R
ADRVS
S
ESR
A
WLA
Q
CGLTVEQ
LA
R
Q
VE
P
E
YTPARK
A
HLYHCDHRGLPLALIS
E
D
G
N
TAW
S
AEYDEWGN
Q
LNEENPH
HVY
Q
PY
RLPGQQ
H
DEESGLYYNRHRYYDPLQGRYITQDP
M
GLKGGWNLY
Q
YPLNP
L
QQ
IDP
M
GL
LQ
T
W
D
DA
R
SGACT
G
G
V
CG
V
LS
RI
IGP
S
KFDS
TA
D
A
A
L
DAL
KET
Q
N
R
S
L
C
N
D
M
EY
S
G
IV
CKD
TN
G
K
YF
ASK
A
ETD
N
L
RK
E
SYPL
-
K
R
KCP
T
GT
D
RV
A
AYHTHG
--
ADSHG
-------
DY
V
DE
F
-
FSS
S
D
KN
LV
R
SKDNN
L
E
---
-
A
FYL
A
TP
D
G
R
F
E
A
L
NNKG
EY
I
F
fig|511145.12.peg.518
Escherichia coli str. K-12 substr. MG1655 (967-1409/1426)
VIRTDDERTH
H
YHYDSQHRLV
F
YTR
I
Q
H
G
EPLVESRYLYDPLGRR
M
AKRVWRRERDLTGWMSLSRKP
E
VTWYGWDGDRLTT
V
Q
T
D
T
TRIQT
V
Y
E
PGSFTPLIRVET
E
N
GE
R
E
K
A
QRRSLA
E
T
LQQ
E
G
S
E
N
G
HG
VVFP
AE
LV
RL
LDRLE
E
EI
R
ADRVS
S
ESR
A
WLA
Q
CGLTVEQ
LA
R
Q
VE
P
E
YTPARK
A
HLYHCDHRGLPLALIS
E
D
G
N
TAW
S
AEYDEWGN
Q
LNEENPH
HVY
Q
PY
RLPGQQ
H
DEESGLYYNRHRYYDPLQGRYITQDP
M
GLKGGWNLY
Q
YPLNP
L
QQ
IDP
M
GL
LQ
T
W
D
DA
R
SGACT
G
G
V
CG
V
LS
RI
IGP
S
KFDS
TA
D
A
A
L
DAL
KET
Q
N
R
S
L
C
N
D
M
EY
S
G
IV
CKD
TN
G
K
YF
ASK
A
ETD
N
L
RK
E
SYPL
-
K
R
KCP
T
GT
D
RV
A
AYHTHG
--
ADSHG
-------
DY
V
DE
F
-
FSS
S
D
KN
LV
R
SKDNN
L
E
---
-
A
FYL
A
TP
D
G
R
F
E
A
L
NNKG
EY
I
F
fig|511145.6.peg.512
Escherichia coli str. K-12 substr. MG1655 (967-1409/1426)
VIRTDDERTH
H
YHYDSQHRLV
F
YTR
I
Q
H
G
EPLVESRYLYDPLGRR
M
AKRVWRRERDLTGWMSLSRKP
E
VTWYGWDGDRLTT
V
Q
T
D
T
TRIQT
V
Y
E
PGSFTPLIRVET
E
N
GE
R
E
K
A
QRRSLA
E
T
LQQ
E
G
S
E
N
G
HG
VVFP
AE
LV
RL
LDRLE
E
EI
R
ADRVS
S
ESR
A
WLA
Q
CGLTVEQ
LA
R
Q
VE
P
E
YTPARK
A
HLYHCDHRGLPLALIS
E
D
G
N
TAW
S
AEYDEWGN
Q
LNEENPH
HVY
Q
PY
RLPGQQ
H
DEESGLYYNRHRYYDPLQGRYITQDP
M
GLKGGWNLY
Q
YPLNP
L
QQ
IDP
M
GL
LQ
T
W
D
DA
R
SGACT
G
G
V
CG
V
LS
RI
IGP
S
KFDS
TA
D
A
A
L
DAL
KET
Q
N
R
S
L
C
N
D
M
EY
S
G
IV
CKD
TN
G
K
YF
ASK
A
ETD
N
L
RK
E
SYPL
-
K
R
KCP
T
GT
D
RV
A
AYHTHG
--
ADSHG
-------
DY
V
DE
F
-
FSS
S
D
KN
LV
R
SKDNN
L
E
---
-
A
FYL
A
TP
D
G
R
F
E
A
L
NNKG
EY
I
F
fig|413997.3.peg.481
Escherichia coli B str. REL606 (967-1409/1426)
VIRTDDERTH
H
YHYDSQHRLV
F
YTR
I
Q
H
G
EPLVESRYLYDPLGRR
M
AKRVWRRERDLTGWMSLSRKP
E
VTWYGWDGDRLTT
V
Q
T
D
T
TRIQT
V
Y
E
PGSFTPLIRVET
E
N
GE
R
E
K
A
QRRSLA
E
T
LQQ
E
G
S
E
N
G
HG
VVFP
AE
LV
RL
LDRLE
E
EI
R
ADRVS
S
ESR
A
WLA
Q
CGLTVEQ
LA
R
Q
VE
P
E
YTPARK
A
HLYHCDHRGLPLALIS
E
D
G
N
TAW
S
AEYDEWGN
Q
LNEENPH
HVY
Q
PY
RLPGQQ
H
DEESGLYYNRHRYYDPLQGRYITQDP
M
GLKGGWNLY
Q
YPLNP
L
QQ
IDP
M
GL
LQ
T
W
D
DA
R
SGACT
G
G
V
CG
V
LS
RI
IGP
S
KFDS
TA
D
A
A
L
DAL
KET
Q
N
R
S
L
C
N
D
M
EY
S
G
IV
CKD
TN
G
K
YF
ASK
A
ETD
N
L
RK
E
SYPL
-
K
R
KCP
T
GT
D
RV
A
AYHTHG
--
ADSHG
-------
DY
V
DE
F
-
FSS
S
D
KN
LV
R
SKDNN
L
E
---
-
A
FYL
A
TP
D
G
R
F
E
A
L
NNKG
EY
I
F
fig|511693.5.peg.486
Escherichia coli BL21 (967-1409/1426)
VIRTDDERTH
H
YHYDSQHRLV
F
YTR
I
Q
H
G
EPLVESRYLYDPLGRR
M
AKRVWRRERDLTGWMSLSRKP
E
VTWYGWDGDRLTT
V
Q
T
D
T
TRIQT
V
Y
E
PGSFTPLIRVET
E
N
GE
R
E
K
A
QRRSLA
E
T
LQQ
E
G
S
E
N
G
HG
VVFP
AE
LV
RL
LDRLE
E
EI
R
ADRVS
S
ESR
A
WLA
Q
CGLTVEQ
LA
R
Q
VE
P
E
YTPARK
A
HLYHCDHRGLPLALIS
E
D
G
N
TAW
S
AEYDEWGN
Q
LNEENPH
HVY
Q
PY
RLPGQQ
H
DEESGLYYNRHRYYDPLQGRYITQDP
M
GLKGGWNLY
Q
YPLNP
L
QQ
IDP
M
GL
LQ
T
W
D
DA
R
SGACT
G
G
V
CG
V
LS
RI
IGP
S
KFDS
TA
D
A
A
L
DAL
KET
Q
N
R
S
L
C
N
D
M
EY
S
G
IV
CKD
TN
G
K
YF
ASK
A
ETD
N
L
RK
E
SYPL
-
K
R
KCP
T
GT
D
RV
A
AYHTHG
--
ADSHG
-------
DY
V
DE
F
-
FSS
S
D
KN
LV
R
SKDNN
L
E
---
-
A
FYL
A
TP
D
G
R
F
E
A
L
NNKG
EY
I
F
fig|469008.4.peg.3264
Escherichia coli BL21(DE3) (967-1409/1426)
VIRTDDERTH
H
YHYDSQHRLV
F
YTR
I
Q
H
G
EPLVESRYLYDPLGRR
M
AKRVWRRERDLTGWMSLSRKP
E
VTWYGWDGDRLTT
V
Q
T
D
T
TRIQT
V
Y
E
PGSFTPLIRVET
E
N
GE
R
E
K
A
QRRSLA
E
T
LQQ
E
G
S
E
N
G
HG
VVFP
AE
LV
RL
LDRLE
E
EI
R
ADRVS
S
ESR
A
WLA
Q
CGLTVEQ
LA
R
Q
VE
P
E
YTPARK
A
HLYHCDHRGLPLALIS
E
D
G
N
TAW
S
AEYDEWGN
Q
LNEENPH
HVY
Q
PY
RLPGQQ
H
DEESGLYYNRHRYYDPLQGRYITQDP
M
GLKGGWNLY
Q
YPLNP
L
QQ
IDP
M
GL
LQ
T
W
D
DA
R
SGACT
G
G
V
CG
V
LS
RI
IGP
S
KFDS
TA
D
A
A
L
DAL
KET
Q
N
R
S
L
C
N
D
M
EY
S
G
IV
CKD
TN
G
K
YF
ASK
A
ETD
N
L
RK
E
SYPL
-
K
R
KCP
T
GT
D
RV
A
AYHTHG
--
ADSHG
-------
DY
V
DE
F
-
FSS
S
D
KN
LV
R
SKDNN
L
E
---
-
A
FYL
A
TP
D
G
R
F
E
A
L
NNKG
EY
I
F
fig|316401.4.peg.630
Escherichia coli ETEC H10407 (967-1409/1426)
VIRTDDERTH
H
YHYDSQHRLV
F
YTR
I
Q
H
G
EPLVESRYLYDPLGRR
M
AKRVWRRERDLTGWMSLSRKP
E
VTWYGWDGDRLTT
V
Q
T
D
T
TRIQT
V
Y
E
PGSFTPLIRVET
E
N
GE
R
E
K
A
QRRSLA
E
T
LQQ
E
G
S
E
N
G
HG
VVFP
AE
LV
RL
LDRLE
E
EI
R
ADRVS
S
ESR
A
WLA
Q
CGLTVEQ
LA
R
Q
VE
P
E
YTPARK
A
HLYHCDHRGLPLALIS
E
D
G
N
TAW
S
AEYDEWGN
Q
LNEENPH
HVY
Q
PY
RLPGQQ
H
DEESGLYYNRHRYYDPLQGRYITQDP
M
GLKGGWNLY
Q
YPLNP
L
QQ
IDP
M
GL
LQ
T
W
D
DA
R
SGACT
G
G
V
CG
V
LS
RI
IGP
S
KFDS
TA
D
A
A
L
DAL
KET
Q
N
R
S
L
C
N
D
M
EY
S
G
IV
CKD
TN
G
K
YF
ASK
A
ETD
N
L
RK
E
SYPL
-
K
R
KCP
T
GT
D
RV
A
AYHTHG
--
ADSHG
-------
DY
V
DE
F
-
FSS
S
D
KN
LV
R
SKDNN
L
E
---
-
A
FYL
A
TP
D
G
R
F
E
A
L
NN
N
G
EY
I
F
fig|749547.3.peg.1423
Escherichia coli MS 187-1 (967-1409/1426)
VIRTDDERTH
H
YHYDSQHRLV
F
YTR
I
Q
H
G
EPLVESRYLYDPLGRR
M
AKRVWRRERDLTGWMSLSRKP
E
VTWYGWDGDRLTT
V
Q
T
D
T
TRIQT
V
Y
E
PGSFTPLIRVET
E
N
GE
R
E
K
A
QRRSLA
E
T
LQQ
E
G
S
E
N
G
HG
VVFP
AE
LV
RL
LDRLE
E
EI
R
ADRVS
S
ESR
A
WLA
Q
CGLTVEQ
LA
R
Q
VE
P
E
YTPARK
A
HLYHCDHRGLPLALIS
E
D
G
N
TAW
S
AEYDEWGN
Q
LNEENPH
H
L
H
Q
PY
RLPGQQ
H
DEESGLYYNRHRYYDPLQGRYITQDP
M
GLKGGWNLY
Q
YPLNP
L
QQ
IDP
M
GL
LQ
T
W
D
DA
R
SGACT
G
G
V
CG
V
LS
RI
IGP
S
KFDS
TA
D
A
A
L
DAL
KET
Q
N
R
S
L
C
N
D
M
EY
S
G
IV
CKD
TN
G
K
YF
ASK
A
ETD
N
L
RK
E
SYPL
-
K
R
KCP
T
GT
D
RV
A
AYHTHG
--
ADSHG
-------
DY
V
DE
F
-
FSS
S
D
KN
LV
R
SKDNN
L
E
---
-
A
FYL
A
TP
D
G
R
F
E
A
L
NNKG
EY
I
F
fig|749548.3.peg.1755
Escherichia coli MS 196-1 (829-1271/1288)
VIRTDDERTH
H
YHYDSQHRLV
F
YTR
I
Q
H
G
EPLVESRYLYDPLGRR
M
AKRVWRRERDLTGWMSLSRKP
E
VTWYGWDGDRLTT
V
Q
T
D
T
TRIQT
V
Y
E
PGSFTPLIRVET
E
N
GE
R
E
K
A
QRRSLA
E
T
LQQ
E
G
S
E
N
G
HG
VVFP
AE
LV
RL
LDRLE
E
EI
R
ADRVS
S
ESR
A
WLA
Q
CGLTVEQ
LA
R
Q
VE
P
E
YTPARK
A
HLYHCDHRGLPLALIS
E
D
G
N
TAW
S
AEYDEWGN
Q
LNEENPH
H
L
H
Q
PY
RLPGQQ
H
DEESGLYYNRHRYYDPLQGRYITQDP
M
GLKGGWNLY
Q
YPLNP
L
QQ
IDP
M
GL
LQ
T
W
D
DA
R
SGACT
G
G
V
CG
V
LS
RI
IGP
S
KFDS
TA
D
A
A
L
DAL
KET
Q
N
R
S
L
C
N
D
M
EY
S
G
IV
CKD
TN
G
K
YF
ASK
A
ETD
N
L
RK
A
SYPL
-
K
R
KCP
T
GT
D
RV
A
AYHTHG
--
ADSHG
-------
DY
V
DE
F
-
FSS
S
D
KN
LV
R
SKDNN
L
E
---
-
A
FYL
A
TP
D
G
R
F
E
A
L
NNKG
EY
I
F
fig|83333.1.peg.3415
Escherichia coli K12 (956-1400/1411)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
E
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDR
S
RIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQM
K
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
T
EGATAWCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
G
Y
Q
LNP
I
SD
IDPLGL
SM
-
W
E
DA
K
SGACT
N
G
L
CG
T
LS
AM
IGP
D
KFDSID
S
T
A
Y
DAL
NKI
N
S
Q
SICEDKE
F
A
GLICKD
NS
G
R
YF
STA
P
NRG
E
-
RK
G
SYP
F
-
N
S
P
CP
N
GTE
K
V
S
AYHTHG
--
ADSHG
-------
E
Y
W
DE
I
-
FS
G
KD
EK
I
V
K
SKDNN
I
K
---
-
SFYLGTP
S
G
N
F
K
A
I
D
N
H
GKEITNRKG
fig|595496.3.peg.3464
Escherichia coli BW2952 (956-1400/1411)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
E
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDR
S
RIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQMQ
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
T
EGATAWCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
G
Y
Q
LNP
I
SD
IDPLGL
SM
-
W
E
DA
K
SGACT
N
G
L
CG
T
LS
AM
IGP
D
KFDSID
S
T
A
Y
DAL
NKI
N
S
Q
SICEDKE
F
A
GLICKD
NS
G
R
YF
STA
P
NRG
E
-
RK
G
SYP
F
-
N
S
P
CP
N
GTE
K
V
S
AYHTHG
--
ADSHG
-------
E
Y
W
DE
I
-
FS
G
KD
EK
I
V
K
SKDNN
I
K
---
-
SFYLGTP
S
G
N
F
K
A
I
D
N
H
GKEITNRKG
fig|536056.3.peg.245
Escherichia coli DH1 (956-1400/1411)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
E
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDR
S
RIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQMQ
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
T
EGATAWCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
G
Y
Q
LNP
I
SD
IDPLGL
SM
-
W
E
DA
K
SGACT
N
G
L
CG
T
LS
AM
IGP
D
KFDSID
S
T
A
Y
DAL
NKI
N
S
Q
SICEDKE
F
A
GLICKD
NS
G
R
YF
STA
P
NRG
E
-
RK
G
SYP
F
-
N
S
P
CP
N
GTE
K
V
S
AYHTHG
--
ADSHG
-------
E
Y
W
DE
I
-
FS
G
KD
EK
I
V
K
SKDNN
I
K
---
-
SFYLGTP
S
G
N
F
K
A
I
D
N
H
GKEITNRKG
fig|316407.3.peg.3646
Escherichia coli W3110 (956-1400/1411)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
E
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDR
S
RIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQMQ
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
T
EGATAWCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
G
Y
Q
LNP
I
SD
IDPLGL
SM
-
W
E
DA
K
SGACT
N
G
L
CG
T
LS
AM
IGP
D
KFDSID
S
T
A
Y
DAL
NKI
N
S
Q
SICEDKE
F
A
GLICKD
NS
G
R
YF
STA
P
NRG
E
-
RK
G
SYP
F
-
N
S
P
CP
N
GTE
K
V
S
AYHTHG
--
ADSHG
-------
E
Y
W
DE
I
-
FS
G
KD
EK
I
V
K
SKDNN
I
K
---
-
SFYLGTP
S
G
N
F
K
A
I
D
N
H
GKEITNRKG
fig|316385.5.peg.3603
Escherichia coli str. K-12 substr. DH10B (956-1400/1411)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
E
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDR
S
RIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQMQ
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
T
EGATAWCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
G
Y
Q
LNP
I
SD
IDPLGL
SM
-
W
E
DA
K
SGACT
N
G
L
CG
T
LS
AM
IGP
D
KFDSID
S
T
A
Y
DAL
NKI
N
S
Q
SICEDKE
F
A
GLICKD
NS
G
R
YF
STA
P
NRG
E
-
RK
G
SYP
F
-
N
S
P
CP
N
GTE
K
V
S
AYHTHG
--
ADSHG
-------
E
Y
W
DE
I
-
FS
G
KD
EK
I
V
K
SKDNN
I
K
---
-
SFYLGTP
S
G
N
F
K
A
I
D
N
H
GKEITNRKG
fig|316385.7.peg.3684
Escherichia coli str. K-12 substr. DH10B (956-1400/1411)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
E
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDR
S
RIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQMQ
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
T
EGATAWCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
G
Y
Q
LNP
I
SD
IDPLGL
SM
-
W
E
DA
K
SGACT
N
G
L
CG
T
LS
AM
IGP
D
KFDSID
S
T
A
Y
DAL
NKI
N
S
Q
SICEDKE
F
A
GLICKD
NS
G
R
YF
STA
P
NRG
E
-
RK
G
SYP
F
-
N
S
P
CP
N
GTE
K
V
S
AYHTHG
--
ADSHG
-------
E
Y
W
DE
I
-
FS
G
KD
EK
I
V
K
SKDNN
I
K
---
-
SFYLGTP
S
G
N
F
K
A
I
D
N
H
GKEITNRKG
fig|511145.12.peg.3581
Escherichia coli str. K-12 substr. MG1655 (956-1400/1411)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
E
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDR
S
RIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQMQ
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
T
EGATAWCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
G
Y
Q
LNP
I
SD
IDPLGL
SM
-
W
E
DA
K
SGACT
N
G
L
CG
T
LS
AM
IGP
D
KFDSID
S
T
A
Y
DAL
NKI
N
S
Q
SICEDKE
F
A
GLICKD
NS
G
R
YF
STA
P
NRG
E
-
RK
G
SYP
F
-
N
S
P
CP
N
GTE
K
V
S
AYHTHG
--
ADSHG
-------
E
Y
W
DE
I
-
FS
G
KD
EK
I
V
K
SKDNN
I
K
---
-
SFYLGTP
S
G
N
F
K
A
I
D
N
H
GKEITNRKG
fig|511145.6.peg.3564
Escherichia coli str. K-12 substr. MG1655 (956-1400/1411)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
E
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDR
S
RIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQMQ
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
T
EGATAWCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
G
Y
Q
LNP
I
SD
IDPLGL
SM
-
W
E
DA
K
SGACT
N
G
L
CG
T
LS
AM
IGP
D
KFDSID
S
T
A
Y
DAL
NKI
N
S
Q
SICEDKE
F
A
GLICKD
NS
G
R
YF
STA
P
NRG
E
-
RK
G
SYP
F
-
N
S
P
CP
N
GTE
K
V
S
AYHTHG
--
ADSHG
-------
E
Y
W
DE
I
-
FS
G
KD
EK
I
V
K
SKDNN
I
K
---
-
SFYLGTP
S
G
N
F
K
A
I
D
N
H
GKEITNRKG
fig|573235.3.peg.4681
Escherichia coli O26:H11 str. 11368 (956-1400/1411)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
E
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKP
E
VTWYGWDGDRLTTIQNDRTRIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
T
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQMQ
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
K
EGAT
E
WCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
G
Y
Q
LNP
I
SD
IDPLGL
SM
-
W
E
DA
K
SGACT
N
G
L
CG
T
LS
AM
IGP
D
KFDSID
S
T
A
Y
DAL
NKI
N
S
Q
SICEDKE
F
A
GLICKD
NS
G
R
YF
STA
P
NRG
E
-
RK
G
SYP
F
-
N
S
P
CP
N
GTE
K
V
S
AYHTHG
--
ADSHG
-------
E
Y
W
DE
I
-
FS
G
KD
EK
I
V
K
SKDNN
I
K
---
-
SFYLGTP
S
G
N
F
K
A
I
D
N
H
GKEITNRKG
fig|413997.3.peg.3489
Escherichia coli B str. REL606 (956-1400/1411)
VIRTDDERTH
Q
YHYDSQHRLVHYTRTQY
A
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKP
E
VTWYGWDGDRLTTIQNDRTRIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
T
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQMQ
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
T
EGATAWCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
G
Y
Q
LNP
I
SD
IDPLGL
SM
-
W
E
DA
K
SGACT
N
G
L
CG
T
LS
AM
IGP
D
KFDSID
S
T
A
Y
DAL
NKI
N
S
Q
SICEDKE
F
A
GLICKD
NS
G
R
YF
STA
P
NRG
E
-
RK
G
SYP
F
-
N
S
P
CP
N
GTE
K
V
S
AYHTHG
--
ADSHG
-------
E
Y
W
DE
I
-
FS
G
KD
EK
I
V
K
SKDNN
I
K
---
-
SFYLGTP
S
G
N
F
K
A
I
D
N
H
GKEITNRKG
fig|511693.5.peg.3505
Escherichia coli BL21 (956-1400/1411)
VIRTDDERTH
Q
YHYDSQHRLVHYTRTQY
A
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKP
E
VTWYGWDGDRLTTIQNDRTRIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
T
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQMQ
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
T
EGATAWCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
G
Y
Q
LNP
I
SD
IDPLGL
SM
-
W
E
DA
K
SGACT
N
G
L
CG
T
LS
AM
IGP
D
KFDSID
S
T
A
Y
DAL
NKI
N
S
Q
SICEDKE
F
A
GLICKD
NS
G
R
YF
STA
P
NRG
E
-
RK
G
SYP
F
-
N
S
P
CP
N
GTE
K
V
S
AYHTHG
--
ADSHG
-------
E
Y
W
DE
I
-
FS
G
KD
EK
I
V
K
SKDNN
I
K
---
-
SFYLGTP
S
G
N
F
K
A
I
D
N
H
GKEITNRKG
fig|469008.4.peg.275
Escherichia coli BL21(DE3) (956-1400/1411)
VIRTDDERTH
Q
YHYDSQHRLVHYTRTQY
A
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKP
E
VTWYGWDGDRLTTIQNDRTRIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
T
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQMQ
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
T
EGATAWCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
G
Y
Q
LNP
I
SD
IDPLGL
SM
-
W
E
DA
K
SGACT
N
G
L
CG
T
LS
AM
IGP
D
KFDSID
S
T
A
Y
DAL
NKI
N
S
Q
SICEDKE
F
A
GLICKD
NS
G
R
YF
STA
P
NRG
E
-
RK
G
SYP
F
-
N
S
P
CP
N
GTE
K
V
S
AYHTHG
--
ADSHG
-------
E
Y
W
DE
I
-
FS
G
KD
EK
I
V
K
SKDNN
I
K
---
-
SFYLGTP
S
G
N
F
K
A
I
D
N
H
GKEITNRKG
fig|670888.3.peg.2766
Escherichia coli 1827-70 (956-1400/1411)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
E
EPL
I
ESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDRTRIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
T
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQMQ
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
K
EGAT
E
WCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
G
Y
Q
LNP
I
SD
IDPLGL
SM
-
W
E
DA
K
SGACT
N
G
L
CG
T
LS
AM
IGP
D
KFDSID
S
T
A
Y
DAL
NKI
N
S
Q
SICEDKE
F
A
GLICKD
NS
G
R
YF
STA
P
NRG
E
-
RK
G
SYP
F
-
N
S
P
CP
N
GTE
K
V
S
AYHTHG
--
ADSHG
-------
E
Y
W
DE
I
-
FS
G
KD
EK
I
V
K
SKDNN
I
K
---
-
SFYLGTP
S
G
N
F
K
A
I
D
N
H
GKEITNRKG
fig|344610.3.peg.122
Escherichia coli 53638 (247-691/702)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
E
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDRTRIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
T
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQMQ
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
T
EGATAWCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
G
Y
Q
LNP
I
SD
IDPLGL
SM
-
W
E
DA
K
SGACT
N
G
L
CG
T
LS
AM
IGP
D
KFDSID
S
T
A
Y
DAL
NKI
N
S
Q
SICEDKE
F
A
GLICKD
NS
G
R
YF
STA
P
NRG
E
-
RK
G
SYP
F
-
N
S
P
CP
N
GTE
K
V
S
AYHTHG
--
ADSHG
-------
E
Y
W
DE
I
-
FS
G
KD
EK
I
V
K
SKDNN
I
K
---
-
SFYLGTP
S
G
N
F
K
A
I
D
N
H
GKEITNRKG
fig|344610.7.peg.2751
Escherichia coli 53638 (247-691/702)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
E
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDRTRIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
T
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQMQ
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
T
EGATAWCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
G
Y
Q
LNP
I
SD
IDPLGL
SM
-
W
E
DA
K
SGACT
N
G
L
CG
T
LS
AM
IGP
D
KFDSID
S
T
A
Y
DAL
NKI
N
S
Q
SICEDKE
F
A
GLICKD
NS
G
R
YF
STA
P
NRG
E
-
RK
G
SYP
F
-
N
S
P
CP
N
GTE
K
V
S
AYHTHG
--
ADSHG
-------
E
Y
W
DE
I
-
FS
G
KD
EK
I
V
K
SKDNN
I
K
---
-
SFYLGTP
S
G
N
F
K
A
I
D
N
H
GKEITNRKG
fig|344601.3.peg.1791
Escherichia coli B171 (956-1400/1411)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
A
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDR
S
RIQTIYQPGSFTPLIRVET
A
TGE
Q
AKTQRRSLAD
T
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQMQ
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
T
EGATAWCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
G
Y
Q
LNP
I
SD
IDPLGL
SM
-
W
E
DA
K
SGACT
N
G
L
CG
T
LS
AM
IGP
D
KFDSID
S
T
A
Y
DAL
NKI
N
S
Q
SICEDKE
F
A
GLICKD
NS
G
R
YF
STA
P
NRG
E
-
RK
G
SYP
F
-
N
S
P
CP
N
GTE
K
V
S
AYHTHG
--
ADSHG
-------
E
Y
W
DE
I
-
FS
G
KD
EK
I
V
K
SKDNN
I
K
---
-
SFYLGTP
S
G
N
F
K
A
I
D
N
H
GKEITNRKG
fig|344601.5.peg.1871
Escherichia coli B171 (956-1400/1411)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
A
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDR
S
RIQTIYQPGSFTPLIRVET
A
TGE
Q
AKTQRRSLAD
T
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQMQ
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
T
EGATAWCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
G
Y
Q
LNP
I
SD
IDPLGL
SM
-
W
E
DA
K
SGACT
N
G
L
CG
T
LS
AM
IGP
D
KFDSID
S
T
A
Y
DAL
NKI
N
S
Q
SICEDKE
F
A
GLICKD
NS
G
R
YF
STA
P
NRG
E
-
RK
G
SYP
F
-
N
S
P
CP
N
GTE
K
V
S
AYHTHG
--
ADSHG
-------
E
Y
W
DE
I
-
FS
G
KD
EK
I
V
K
SKDNN
I
K
---
-
SFYLGTP
S
G
N
F
K
A
I
D
N
H
GKEITNRKG
fig|481805.3.peg.246
Escherichia coli ATCC 8739 (956-1400/1411)
VIRTDDERTH
Q
YHYDSQHRLVHYTRTQY
A
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKP
E
VTWYGWDGDRLTTIQNDR
S
RIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQMQ
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
K
EG
T
T
E
WCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
G
Y
Q
LNP
I
SD
IDPLGL
SM
-
W
E
DA
K
SGACT
N
G
L
CG
T
LS
AM
IGP
D
KFDSID
S
T
A
Y
DAL
NKI
N
S
Q
SICEDKE
F
A
GLICKD
NS
G
R
YF
STA
P
NRG
E
-
RK
G
SYP
F
-
N
S
P
CP
N
GTE
K
V
S
AYHTHG
--
ADSHG
-------
E
Y
W
DE
I
-
FS
G
KD
EK
I
V
K
SKDNN
I
K
---
-
SFYLGTP
S
G
N
F
K
A
I
D
N
H
GKEITNRKG
fig|481805.6.peg.256
Escherichia coli ATCC 8739 (956-1400/1411)
VIRTDDERTH
Q
YHYDSQHRLVHYTRTQY
A
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKP
E
VTWYGWDGDRLTTIQNDR
S
RIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQMQ
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
K
EG
T
T
E
WCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
G
Y
Q
LNP
I
SD
IDPLGL
SM
-
W
E
DA
K
SGACT
N
G
L
CG
T
LS
AM
IGP
D
KFDSID
S
T
A
Y
DAL
NKI
N
S
Q
SICEDKE
F
A
GLICKD
NS
G
R
YF
STA
P
NRG
E
-
RK
G
SYP
F
-
N
S
P
CP
N
GTE
K
V
S
AYHTHG
--
ADSHG
-------
E
Y
W
DE
I
-
FS
G
KD
EK
I
V
K
SKDNN
I
K
---
-
SFYLGTP
S
G
N
F
K
A
I
D
N
H
GKEITNRKG
fig|331112.3.peg.3453
Escherichia coli HS (956-1400/1411)
VIRTDDERTH
Q
YHYDSQHRLVHYTRTQY
A
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKP
E
VTWYGWDGDRLTTIQNDRTRIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
T
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQMQ
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
K
EGAT
E
WCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
G
Y
Q
LNP
I
SD
IDPLGL
SM
-
W
E
DA
K
SGACT
N
G
L
CG
T
LS
AM
IGP
D
KFDSID
S
T
A
Y
DAL
NKI
N
S
Q
SICEDKE
F
A
GLICKD
NS
G
R
YF
STA
P
NRG
E
-
RK
G
SYP
F
-
N
S
P
CP
N
GTE
K
V
S
AYHTHG
--
ADSHG
-------
E
Y
W
DE
I
-
FS
G
KD
EK
I
V
K
SKDNN
I
K
---
-
SFYLGTP
S
G
N
F
K
A
I
D
N
H
GKEITNRKG
fig|331112.6.peg.3587
Escherichia coli HS (956-1400/1411)
VIRTDDERTH
Q
YHYDSQHRLVHYTRTQY
A
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKP
E
VTWYGWDGDRLTTIQNDRTRIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
T
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQMQ
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
K
EGAT
E
WCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
G
Y
Q
LNP
I
SD
IDPLGL
SM
-
W
E
DA
K
SGACT
N
G
L
CG
T
LS
AM
IGP
D
KFDSID
S
T
A
Y
DAL
NKI
N
S
Q
SICEDKE
F
A
GLICKD
NS
G
R
YF
STA
P
NRG
E
-
RK
G
SYP
F
-
N
S
P
CP
N
GTE
K
V
S
AYHTHG
--
ADSHG
-------
E
Y
W
DE
I
-
FS
G
KD
EK
I
V
K
SKDNN
I
K
---
-
SFYLGTP
S
G
N
F
K
A
I
D
N
H
GKEITNRKG
fig|316401.4.peg.4223
Escherichia coli ETEC H10407 (956-1400/1411)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
E
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDRTRIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQMQ
N
QMDPVYTPARKIHLYHCDHRGL
Q
LALIS
T
EGATAWCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
G
Y
Q
LNP
I
SD
IDPLGL
SM
-
W
E
DA
K
SGACT
N
G
L
CG
T
LS
AM
IGP
D
KFDSID
S
T
A
Y
DAL
NKI
N
S
Q
SICEDKE
F
A
GLICKD
NS
G
R
YF
STA
P
NRG
E
-
RK
G
SYP
F
-
N
S
P
CP
N
GTE
K
V
S
AYHTHG
--
ADSHG
-------
E
Y
W
DE
I
-
FS
G
KD
EK
I
V
K
SKDNN
I
K
---
-
SFYLGTP
S
G
N
F
K
A
I
D
N
H
GKEITNRKG
fig|566546.4.peg.3830
Escherichia coli W (956-1400/1411)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
A
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDR
S
RIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
T
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQMQ
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
T
EGATAWCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
G
Y
Q
LNP
I
SD
IDPLGL
SM
-
W
E
DA
K
SGACT
N
G
L
CG
T
LS
AM
IGP
D
KFDSID
S
T
A
Y
DAL
NKI
N
S
Q
SICEDKE
F
A
GLICKD
NS
G
R
YF
STA
P
NRG
E
-
RK
G
SYP
F
-
N
S
P
CP
N
GTE
K
V
S
AYHTHG
--
ADSHG
-------
E
Y
W
DE
I
-
FS
G
KD
EK
I
V
K
SKDNN
I
K
---
-
SFYLGTP
S
G
N
F
K
A
I
D
N
H
GKEITNRKG
fig|409438.11.peg.4043
Escherichia coli SE11 (956-1400/1411)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
A
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDRTRIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQMQ
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
T
EGATAWCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
G
Y
Q
LNP
I
SD
IDPLGL
SM
-
W
E
DA
K
SGACT
N
G
L
CG
T
LS
AM
IGP
D
KFDSID
S
T
A
Y
DAL
NKI
N
S
Q
SICEDKE
F
A
GLICKD
NS
G
R
YF
STA
P
NRG
E
-
RK
G
SYP
F
-
N
S
P
CP
N
GTE
K
V
S
AYHTHG
--
ADSHG
-------
E
Y
W
DE
I
-
FS
G
KD
EK
I
V
K
SKDNN
I
K
---
-
S
I
YLGTP
S
G
N
F
K
A
I
D
N
H
GKEITNRKG
fig|585396.4.peg.4438
Escherichia coli O111:H- str. 11128 (956-1400/1411)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
A
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDR
S
RIQTIYQPGSFTPLIRVET
A
TGE
L
A
R
TQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQMQ
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
K
EG
T
T
E
WCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
G
Y
Q
LNP
I
SD
IDPLGL
SM
-
W
E
DA
K
SGACT
N
G
L
CG
T
LS
AM
IGP
D
KFDSID
S
T
A
Y
DAL
NKI
N
S
Q
SICEDKE
F
A
GLICKD
NS
G
R
YF
STA
P
NRG
E
-
RK
G
SYP
F
-
N
S
P
CP
N
GTE
K
V
S
AYHTHG
--
ADSHG
-------
E
Y
W
DE
I
-
FS
G
KD
EK
I
V
K
SKDNN
I
K
---
-
SFYLGTP
S
G
N
F
K
A
I
D
N
H
GKEITNRKG
fig|331111.12.peg.4332
Escherichia coli E24377A (957-1400/1411)
IRTDDERTHRYHYDSQHRLVHYTRTQY
A
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDR
S
RIQTIYQPGSFTPLIRVET
A
TGE
L
A
R
TQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQMQ
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
T
EGATAWCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
G
Y
Q
LNP
I
SD
IDPLGL
SM
-
W
E
DA
K
SGACT
N
G
L
CG
T
LS
AM
IGP
D
KFDSID
S
T
A
Y
DAL
NKI
N
S
Q
SICEDKE
F
A
GLICKD
NS
G
R
YF
STA
P
NRG
E
-
RK
G
SYP
F
-
N
S
P
CP
N
GTE
K
V
S
AYHTHG
--
ADSHG
-------
E
Y
W
DE
I
-
FS
G
KD
EK
I
V
K
SKDNN
I
K
---
-
SFYLGTP
S
G
N
F
K
A
I
D
N
H
GKEITNRKG
fig|331111.3.peg.1735
Escherichia coli E24377A (957-1400/1411)
IRTDDERTHRYHYDSQHRLVHYTRTQY
A
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDR
S
RIQTIYQPGSFTPLIRVET
A
TGE
L
A
R
TQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQMQ
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
T
EGATAWCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
G
Y
Q
LNP
I
SD
IDPLGL
SM
-
W
E
DA
K
SGACT
N
G
L
CG
T
LS
AM
IGP
D
KFDSID
S
T
A
Y
DAL
NKI
N
S
Q
SICEDKE
F
A
GLICKD
NS
G
R
YF
STA
P
NRG
E
-
RK
G
SYP
F
-
N
S
P
CP
N
GTE
K
V
S
AYHTHG
--
ADSHG
-------
E
Y
W
DE
I
-
FS
G
KD
EK
I
V
K
SKDNN
I
K
---
-
SFYLGTP
S
G
N
F
K
A
I
D
N
H
GKEITNRKG
fig|562.375.peg.421
Escherichia coli EC4100B (957-1400/1411)
IRTDDERTHRYHYDSQHRLVHYTRTQY
A
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDR
S
RIQTIYQPGSFTPLIRVET
A
TGE
L
A
R
TQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQMQ
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
T
EGATAWCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
G
Y
Q
LNP
I
SD
IDPLGL
SM
-
W
E
DA
K
SGACT
N
G
L
CG
T
LS
AM
IGP
D
KFDSID
S
T
A
Y
DAL
NKI
N
S
Q
SICEDKE
F
A
GLICKD
NS
G
R
YF
STA
P
NRG
E
-
RK
G
SYP
F
-
N
S
P
CP
N
GTE
K
V
S
AYHTHG
--
ADSHG
-------
E
Y
W
DE
I
-
FS
G
KD
EK
I
V
K
SKDNN
I
K
---
-
SFYLGTP
S
G
N
F
K
A
I
D
N
H
GKEITNRKG
fig|340184.3.peg.375
Escherichia coli B7A (957-1400/1411)
IRTDDERTHRYHYDSQHRLVHYTRTQY
A
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDR
S
RIQTIYQPGSFTPLIRVET
A
TGE
L
A
R
TQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQMQ
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
K
EG
T
T
E
WCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
G
Y
Q
LNP
I
SD
IDPLGL
SM
-
W
E
DA
K
SGACT
N
G
L
CG
T
LS
AM
IGP
D
KFDSID
S
T
A
Y
DAL
NKI
N
S
Q
SICEDKE
F
A
GLICKD
NS
G
R
YF
STA
P
NRG
E
-
RK
G
SYP
F
-
N
S
P
CP
N
GTE
K
V
S
AYHTHG
--
ADSHG
-------
E
Y
W
DE
I
-
FS
G
KD
EK
I
V
K
SKDNN
I
K
---
-
SFYLGTP
S
G
N
F
K
A
I
D
N
H
GKEITNRKG
fig|340184.6.peg.395
Escherichia coli B7A (957-1400/1411)
IRTDDERTHRYHYDSQHRLVHYTRTQY
A
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDR
S
RIQTIYQPGSFTPLIRVET
A
TGE
L
A
R
TQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQMQ
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
K
EG
T
T
E
WCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
G
Y
Q
LNP
I
SD
IDPLGL
SM
-
W
E
DA
K
SGACT
N
G
L
CG
T
LS
AM
IGP
D
KFDSID
S
T
A
Y
DAL
NKI
N
S
Q
SICEDKE
F
A
GLICKD
NS
G
R
YF
STA
P
NRG
E
-
RK
G
SYP
F
-
N
S
P
CP
N
GTE
K
V
S
AYHTHG
--
ADSHG
-------
E
Y
W
DE
I
-
FS
G
KD
EK
I
V
K
SKDNN
I
K
---
-
SFYLGTP
S
G
N
F
K
A
I
D
N
H
GKEITNRKG
fig|679206.4.peg.2131
Escherichia coli MS 119-7 (35-478/489)
IRTDDERTHRYHYDSQHRLVHYTRTQY
A
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDR
S
RIQTIYQPGSFTPLIRVET
A
TGE
L
A
R
TQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQMQ
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
T
EGATAWCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLK
A
GWNLY
G
Y
Q
LNP
I
SD
IDPLGL
SM
-
W
E
DA
K
SGACT
N
G
L
CG
T
LS
AM
IGP
D
KFDSID
S
T
A
Y
DAL
NKI
N
S
Q
SICEDKE
F
A
GLICKD
NS
G
R
YF
STA
P
NRG
E
-
RK
G
SYP
F
-
N
S
P
CP
N
GTE
K
V
S
AYHTHG
--
ADSHG
-------
E
Y
W
DE
I
-
FS
G
KD
EK
I
V
K
SKDNN
I
K
---
-
SFYLGTP
S
G
N
F
K
A
I
D
N
H
GKEITNRKG
fig|656414.3.peg.3971
Escherichia coli H736 (1-425/436)
M
HYTRTQY
E
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDRTRIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQMQ
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
T
EGATAWCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
G
Y
Q
LNP
I
SD
IDPLGL
SM
-
W
E
DA
K
SGACT
N
G
L
CG
T
LS
AM
IGP
D
KFDSID
S
T
A
Y
G
AL
NKI
N
S
Q
SICEDKE
F
A
GLICKD
NS
G
R
YF
STA
P
NRG
E
-
RK
G
SYP
F
-
N
S
P
CP
N
GTE
K
V
S
AYHTHG
--
ADSHG
-------
E
Y
W
DE
I
-
FS
G
KD
EK
I
V
K
SKDNN
I
K
---
-
SFYLGTP
S
G
N
F
K
A
I
D
N
H
GKEITNRKG
fig|340185.3.peg.4463
Escherichia coli E22 (34-456/467)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
A
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDR
S
RIQTIYQPGSFTPLIRVET
A
TGE
Q
AKTQRRSLAD
T
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQMQ
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
T
EGATAWCAEYDEWGNLLNEENPHQLQQLIR
----------------------
LQGRYITQDPIGLKGGWNLY
G
Y
Q
LNP
I
SD
IDPLGL
SM
-
W
E
DA
K
SGACT
N
G
L
CG
T
LS
AM
IGP
D
KFDSID
S
T
A
Y
DAL
NKI
N
S
Q
SICEDKE
F
A
GLICKD
NS
G
R
YF
STA
P
NRG
E
-
RK
G
SYP
F
-
N
S
P
CP
N
GTE
K
V
S
AYHTHG
--
ADSHG
-------
E
Y
W
DE
I
-
FS
G
KD
EK
I
V
K
SKDNN
I
K
---
-
SFYLGTP
S
G
N
F
K
A
I
D
N
H
GKEITNRKG
fig|585395.4.peg.4804
Escherichia coli O103:H2 str. 12009 (956-1378/1389)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
A
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDR
S
RIQTIYQPGSFTPLIRVET
A
TGE
Q
AKTQRRSLAD
T
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQMQ
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
T
EGATAWCAEYDEWGNLLNEENPHQLQQLIR
----------------------
LQGRYITQDPIGLKGGWNLY
G
Y
Q
LNP
I
SD
IDPLGL
SM
-
W
E
DA
K
SGACT
N
G
L
CG
T
LS
AM
IGP
D
KFDSID
S
T
A
Y
DAL
NKI
N
S
Q
SICEDKE
F
A
GLICKD
NS
G
R
YF
STA
P
NRG
E
-
RK
G
SYP
F
-
N
S
P
CP
N
GTE
K
V
S
AYHTHG
--
ADSHG
-------
E
Y
W
DE
I
-
FS
G
KD
EK
I
V
K
SKDNN
I
K
---
-
SFYLGTP
S
G
N
F
K
A
I
D
N
H
GKEITNRKG
fig|340185.4.peg.4706
Escherichia coli E22 (1-403/414)
M
HYTRTQY
A
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDR
S
RIQTIYQPGSFTPLIRVET
A
TGE
Q
AKTQRRSLAD
T
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQMQ
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
T
EGATAWCAEYDEWGNLLNEENPHQLQQLIR
----------------------
LQGRYITQDPIGLKGGWNLY
G
Y
Q
LNP
I
SD
IDPLGL
SM
-
W
E
DA
K
SGACT
N
G
L
CG
T
LS
AM
IGP
D
KFDSID
S
T
A
Y
DAL
NKI
N
S
Q
SICEDKE
F
A
GLICKD
NS
G
R
YF
STA
P
NRG
E
-
RK
G
SYP
F
-
N
S
P
CP
N
GTE
K
V
S
AYHTHG
--
ADSHG
-------
E
Y
W
DE
I
-
FS
G
KD
EK
I
V
K
SKDNN
I
K
---
-
SFYLGTP
S
G
N
F
K
A
I
D
N
H
GKEITNRKG
fig|340186.3.peg.1242
Escherichia coli E110019 (772-1198/1210)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
E
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDR
S
RIQTIYQPGSFTPLIRVET
A
TGE
Q
AKTQRRSLAD
T
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQMQ
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
T
EGATAWCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
T
YPL
S
PV
NS
M
DPLGL
YE
-
F
-
--
-
-----
-
-
-
--
-
--
--
---
-
K
SKN
IDD
I
G
I
F
AL
AMC
N
G
ESI
N
E
N
KEY
G
GLICK
-
KQ
GEYF
PMN
P
ISS
N
-
DN
D
S
VD
L
R
N
I
KCP
E
G
S
ERV
G
D
YHTHG
FYS
D
DK
G
NKVTKEN
D
V
Y
D
S
L
N
FSSKD
--
L
T
N
S
YM
N
G
M
G
KKE
Y
S
S
YLGTPN
N
T
Y
L
K
Y
N
P
K
A
K
fig|340186.5.peg.1284
Escherichia coli E110019 (772-1198/1210)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
E
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDR
S
RIQTIYQPGSFTPLIRVET
A
TGE
Q
AKTQRRSLAD
T
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQMQ
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
T
EGATAWCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
T
YPL
S
PV
NS
M
DPLGL
YE
-
F
-
--
-
-----
-
-
-
--
-
--
--
---
-
K
SKN
IDD
I
G
I
F
AL
AMC
N
G
ESI
N
E
N
KEY
G
GLICK
-
KQ
GEYF
PMN
P
ISS
N
-
DN
D
S
VD
L
R
N
I
KCP
E
G
S
ERV
G
D
YHTHG
FYS
D
DK
G
NKVTKEN
D
V
Y
D
S
L
N
FSSKD
--
L
T
N
S
YM
N
G
M
G
KKE
Y
S
S
YLGTPN
N
T
Y
L
K
Y
N
P
K
A
K
fig|585395.4.peg.4862
Escherichia coli O103:H2 str. 12009 (956-1382/1394)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
A
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDR
S
RIQTIYQPGSFTPLIRVET
A
TGE
Q
AKTQRRSLAD
T
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQMQ
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
T
EGATAWCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
T
YPL
S
PV
NS
M
DPLGL
YE
-
F
-
--
-
-----
-
-
-
--
-
--
--
---
-
K
SKN
IDD
I
G
I
F
AL
AMC
N
G
ESI
N
E
N
KEY
G
GLICK
-
KQ
GEY
L
PMN
P
ISS
N
-
DN
D
S
VD
L
R
N
I
KCP
E
G
S
ERV
G
D
YHTHG
FYS
D
DK
G
NKVTKEN
D
V
Y
D
S
L
N
FSSKD
--
L
T
N
S
YM
N
G
M
E
KKE
Y
S
S
YLGTPN
N
T
Y
L
K
Y
N
P
K
A
K
fig|562.371.peg.1871
Escherichia coli 1044A (956-1382/1394)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
E
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDRTRIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTV
A
QMQ
S
QMDPVYTPARKIHLYHCDHRGLPLALIS
K
EGAT
E
WCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
T
YPL
S
PV
NG
M
DPLGL
YE
-
F
-
--
-
-----
-
-
-
--
-
--
--
---
-
K
SKN
IDD
I
G
I
F
AL
AMC
N
G
ESI
N
E
N
KEY
G
GLICK
-
KQ
GEYF
PMN
P
ISS
N
-
DN
D
S
VD
L
R
N
I
KCP
E
G
S
ERV
G
D
YHTHG
FYS
D
DK
G
NKVTKEN
D
V
Y
D
S
L
N
FSSKD
--
L
T
N
S
YM
N
G
M
G
KKE
C
S
S
YLGTPN
N
T
Y
L
K
Y
N
P
K
A
K
fig|83334.1.peg.4839
Escherichia coli O157:H7 (956-1382/1394)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
E
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDRTRIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTV
A
QMQ
S
QMDPVYTPARKIHLYHCDHRGLPLALIS
K
EGAT
E
WCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
T
YPL
S
PV
NG
M
DPLGL
YE
-
F
-
--
-
-----
-
-
-
--
-
--
--
---
-
K
SKN
IDD
I
G
I
F
AL
AMC
N
G
ESI
N
E
N
KEY
G
GLICK
-
KQ
GEYF
PMN
P
ISS
N
-
DN
D
S
VD
L
R
N
I
KCP
E
G
S
ERV
G
D
YHTHG
FYS
D
DK
G
NKVTKEN
D
V
Y
D
S
L
N
FSSKD
--
L
T
N
S
YM
N
G
M
G
KKE
C
S
S
YLGTPN
N
T
Y
L
K
Y
N
P
K
A
K
fig|478006.5.peg.2164
Escherichia coli O157:H7 str. EC4501 (956-1382/1394)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
E
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDRTRIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTV
A
QMQ
S
QMDPVYTPARKIHLYHCDHRGLPLALIS
K
EGAT
E
WCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
T
YPL
S
PV
NG
M
DPLGL
YE
-
F
-
--
-
-----
-
-
-
--
-
--
--
---
-
K
SKN
IDD
I
G
I
F
AL
AMC
N
G
ESI
N
E
N
KEY
G
GLICK
-
KQ
GEYF
PMN
P
ISS
N
-
DN
D
S
VD
L
R
N
I
KCP
E
G
S
ERV
G
D
YHTHG
FYS
D
DK
G
NKVTKEN
D
V
Y
D
S
L
N
FSSKD
--
L
T
N
S
YM
N
G
M
G
KKE
C
S
S
YLGTPN
N
T
Y
L
K
Y
N
P
K
A
K
fig|386585.9.peg.5086
Escherichia coli O157:H7 str. Sakai (956-1382/1394)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
E
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDRTRIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTV
A
QMQ
S
QMDPVYTPARKIHLYHCDHRGLPLALIS
K
EGAT
E
WCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
T
YPL
S
PV
NG
M
DPLGL
YE
-
F
-
--
-
-----
-
-
-
--
-
--
--
---
-
K
SKN
IDD
I
G
I
F
AL
AMC
N
G
ESI
N
E
N
KEY
G
GLICK
-
KQ
GEYF
PMN
P
ISS
N
-
DN
D
S
VD
L
R
N
I
KCP
E
G
S
ERV
G
D
YHTHG
FYS
D
DK
G
NKVTKEN
D
V
Y
D
S
L
N
FSSKD
--
L
T
N
S
YM
N
G
M
G
KKE
C
S
S
YLGTPN
N
T
Y
L
K
Y
N
P
K
A
K
fig|502346.5.peg.1734
Escherichia coli O157:H7 str. TW14588 (956-1382/1394)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
E
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDRTRIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTV
A
QMQ
S
QMDPVYTPARKIHLYHCDHRGLPLALIS
K
EGAT
E
WCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
T
YPL
S
PV
NG
M
DPLGL
YE
-
F
-
--
-
-----
-
-
-
--
-
--
--
---
-
K
SKN
IDD
I
G
I
F
AL
AMC
N
G
ESI
N
E
N
KEY
G
GLICK
-
KQ
GEYF
PMN
P
ISS
N
-
DN
D
S
VD
L
R
N
I
KCP
E
G
S
ERV
G
D
YHTHG
FYS
D
DK
G
NKVTKEN
D
V
Y
D
S
L
N
FSSKD
--
L
T
N
S
YM
N
G
M
G
KKE
C
S
S
YLGTPN
N
T
Y
L
K
Y
N
P
K
A
K
fig|478008.5.peg.2068
Escherichia coli O157:H7 str. EC869 (956-1382/1394)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
E
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDRTRIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTV
A
QMQ
S
QMDPVYTPARKIHLYHCDHRGLPLALIS
K
EGAT
E
WCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
T
YPL
S
PV
NG
M
DPLGL
YE
-
F
-
--
-
-----
-
-
-
--
-
--
--
---
-
K
SKN
IDD
I
G
I
F
AL
AMC
N
G
ESI
N
E
N
KEY
G
GLICK
-
KQ
GEYF
PMN
P
ISS
N
-
DN
D
S
VD
L
R
N
I
KCP
E
G
S
ERV
G
D
YHTHG
FYS
D
DK
G
NKVTKEN
D
V
Y
D
S
L
N
FSSKD
--
L
T
N
S
YM
N
G
M
G
KKE
C
S
S
YLGTPN
N
T
Y
L
K
Y
N
P
K
A
K
fig|562.373.peg.2622
Escherichia coli 1125A (956-1382/1394)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
E
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDRTRIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTV
A
QMQ
S
QMDPVYTPARKIHLYHCDHRGLPLALIS
K
EGAT
E
WCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
T
YPL
S
PV
NG
M
DPLGL
YE
-
F
-
--
-
-----
-
-
-
--
-
--
--
---
-
K
SKN
IDD
I
G
I
F
AL
AMC
N
G
ESI
N
E
N
KEY
G
GLICK
-
KQ
GEYF
PMN
P
ISS
N
-
DN
D
S
VD
L
R
N
I
KCP
E
G
S
ERV
G
D
YHTHG
FYS
D
DK
G
NKVTKEN
D
V
Y
D
S
L
N
FSSKD
--
L
T
N
S
YM
N
G
M
G
KKE
C
S
S
YLGTPN
N
T
Y
L
K
Y
N
P
K
A
K
fig|562.372.peg.3653
Escherichia coli 1212A (956-1382/1394)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
E
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDRTRIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTV
A
QMQ
S
QMDPVYTPARKIHLYHCDHRGLPLALIS
K
EGAT
E
WCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
T
YPL
S
PV
NG
M
DPLGL
YE
-
F
-
--
-
-----
-
-
-
--
-
--
--
---
-
K
SKN
IDD
I
G
I
F
AL
AMC
N
G
ESI
N
E
N
KEY
G
GLICK
-
KQ
GEYF
PMN
P
ISS
N
-
DN
D
S
VD
L
R
N
I
KCP
E
G
S
ERV
G
D
YHTHG
FYS
D
DK
G
NKVTKEN
D
V
Y
D
S
L
N
FSSKD
--
L
T
N
S
YM
N
G
M
G
KKE
C
S
S
YLGTPN
N
T
Y
L
K
Y
N
P
K
A
K
fig|562.374.peg.3612
Escherichia coli 536A (956-1382/1394)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
E
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDRTRIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTV
A
QMQ
S
QMDPVYTPARKIHLYHCDHRGLPLALIS
K
EGAT
E
WCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
T
YPL
S
PV
NG
M
DPLGL
YE
-
F
-
--
-
-----
-
-
-
--
-
--
--
---
-
K
SKN
IDD
I
G
I
F
AL
AMC
N
G
ESI
N
E
N
KEY
G
GLICK
-
KQ
GEYF
PMN
P
ISS
N
-
DN
D
S
VD
L
R
N
I
KCP
E
G
S
ERV
G
D
YHTHG
FYS
D
DK
G
NKVTKEN
D
V
Y
D
S
L
N
FSSKD
--
L
T
N
S
YM
N
G
M
G
KKE
C
S
S
YLGTPN
N
T
Y
L
K
Y
N
P
K
A
K
fig|444454.5.peg.3970
Escherichia coli O157:H7 str. EC4024 (956-1382/1394)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
E
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDRTRIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTV
A
QMQ
S
QMDPVYTPARKIHLYHCDHRGLPLALIS
K
EGAT
E
WCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
T
YPL
S
PV
NG
M
DPLGL
YE
-
F
-
--
-
-----
-
-
-
--
-
--
--
---
-
K
SKN
IDD
I
G
I
F
AL
AMC
N
G
ESI
N
E
N
KEY
G
GLICK
-
KQ
GEYF
PMN
P
ISS
N
-
DN
D
S
VD
L
R
N
I
KCP
E
G
S
ERV
G
D
YHTHG
FYS
D
DK
G
NKVTKEN
D
V
Y
D
S
L
N
FSSKD
--
L
T
N
S
YM
N
G
M
G
KKE
C
S
S
YLGTPN
N
T
Y
L
K
Y
N
P
K
A
K
fig|444449.5.peg.3425
Escherichia coli O157:H7 str. EC4042 (956-1382/1394)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
E
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDRTRIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTV
A
QMQ
S
QMDPVYTPARKIHLYHCDHRGLPLALIS
K
EGAT
E
WCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
T
YPL
S
PV
NG
M
DPLGL
YE
-
F
-
--
-
-----
-
-
-
--
-
--
--
---
-
K
SKN
IDD
I
G
I
F
AL
AMC
N
G
ESI
N
E
N
KEY
G
GLICK
-
KQ
GEYF
PMN
P
ISS
N
-
DN
D
S
VD
L
R
N
I
KCP
E
G
S
ERV
G
D
YHTHG
FYS
D
DK
G
NKVTKEN
D
V
Y
D
S
L
N
FSSKD
--
L
T
N
S
YM
N
G
M
G
KKE
C
S
S
YLGTPN
N
T
Y
L
K
Y
N
P
K
A
K
fig|444448.5.peg.2180
Escherichia coli O157:H7 str. EC4045 (956-1382/1394)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
E
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDRTRIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTV
A
QMQ
S
QMDPVYTPARKIHLYHCDHRGLPLALIS
K
EGAT
E
WCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
T
YPL
S
PV
NG
M
DPLGL
YE
-
F
-
--
-
-----
-
-
-
--
-
--
--
---
-
K
SKN
IDD
I
G
I
F
AL
AMC
N
G
ESI
N
E
N
KEY
G
GLICK
-
KQ
GEYF
PMN
P
ISS
N
-
DN
D
S
VD
L
R
N
I
KCP
E
G
S
ERV
G
D
YHTHG
FYS
D
DK
G
NKVTKEN
D
V
Y
D
S
L
N
FSSKD
--
L
T
N
S
YM
N
G
M
G
KKE
C
S
S
YLGTPN
N
T
Y
L
K
Y
N
P
K
A
K
fig|444453.5.peg.2322
Escherichia coli O157:H7 str. EC4076 (956-1382/1394)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
E
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDRTRIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTV
A
QMQ
S
QMDPVYTPARKIHLYHCDHRGLPLALIS
K
EGAT
E
WCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
T
YPL
S
PV
NG
M
DPLGL
YE
-
F
-
--
-
-----
-
-
-
--
-
--
--
---
-
K
SKN
IDD
I
G
I
F
AL
AMC
N
G
ESI
N
E
N
KEY
G
GLICK
-
KQ
GEYF
PMN
P
ISS
N
-
DN
D
S
VD
L
R
N
I
KCP
E
G
S
ERV
G
D
YHTHG
FYS
D
DK
G
NKVTKEN
D
V
Y
D
S
L
N
FSSKD
--
L
T
N
S
YM
N
G
M
G
KKE
C
S
S
YLGTPN
N
T
Y
L
K
Y
N
P
K
A
K
fig|444452.5.peg.1790
Escherichia coli O157:H7 str. EC4113 (956-1382/1394)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
E
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDRTRIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTV
A
QMQ
S
QMDPVYTPARKIHLYHCDHRGLPLALIS
K
EGAT
E
WCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
T
YPL
S
PV
NG
M
DPLGL
YE
-
F
-
--
-
-----
-
-
-
--
-
--
--
---
-
K
SKN
IDD
I
G
I
F
AL
AMC
N
G
ESI
N
E
N
KEY
G
GLICK
-
KQ
GEYF
PMN
P
ISS
N
-
DN
D
S
VD
L
R
N
I
KCP
E
G
S
ERV
G
D
YHTHG
FYS
D
DK
G
NKVTKEN
D
V
Y
D
S
L
N
FSSKD
--
L
T
N
S
YM
N
G
M
G
KKE
C
S
S
YLGTPN
N
T
Y
L
K
Y
N
P
K
A
K
fig|444450.8.peg.5262
Escherichia coli O157:H7 str. EC4115 (956-1382/1394)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
E
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDRTRIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTV
A
QMQ
S
QMDPVYTPARKIHLYHCDHRGLPLALIS
K
EGAT
E
WCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
T
YPL
S
PV
NG
M
DPLGL
YE
-
F
-
--
-
-----
-
-
-
--
-
--
--
---
-
K
SKN
IDD
I
G
I
F
AL
AMC
N
G
ESI
N
E
N
KEY
G
GLICK
-
KQ
GEYF
PMN
P
ISS
N
-
DN
D
S
VD
L
R
N
I
KCP
E
G
S
ERV
G
D
YHTHG
FYS
D
DK
G
NKVTKEN
D
V
Y
D
S
L
N
FSSKD
--
L
T
N
S
YM
N
G
M
G
KKE
C
S
S
YLGTPN
N
T
Y
L
K
Y
N
P
K
A
K
fig|444451.5.peg.2836
Escherichia coli O157:H7 str. EC4196 (956-1382/1394)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
E
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDRTRIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTV
A
QMQ
S
QMDPVYTPARKIHLYHCDHRGLPLALIS
K
EGAT
E
WCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
T
YPL
S
PV
NG
M
DPLGL
YE
-
F
-
--
-
-----
-
-
-
--
-
--
--
---
-
K
SKN
IDD
I
G
I
F
AL
AMC
N
G
ESI
N
E
N
KEY
G
GLICK
-
KQ
GEYF
PMN
P
ISS
N
-
DN
D
S
VD
L
R
N
I
KCP
E
G
S
ERV
G
D
YHTHG
FYS
D
DK
G
NKVTKEN
D
V
Y
D
S
L
N
FSSKD
--
L
T
N
S
YM
N
G
M
G
KKE
C
S
S
YLGTPN
N
T
Y
L
K
Y
N
P
K
A
K
fig|444447.5.peg.2346
Escherichia coli O157:H7 str. EC4206 (956-1382/1394)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
E
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDRTRIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTV
A
QMQ
S
QMDPVYTPARKIHLYHCDHRGLPLALIS
K
EGAT
E
WCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
T
YPL
S
PV
NG
M
DPLGL
YE
-
F
-
--
-
-----
-
-
-
--
-
--
--
---
-
K
SKN
IDD
I
G
I
F
AL
AMC
N
G
ESI
N
E
N
KEY
G
GLICK
-
KQ
GEYF
PMN
P
ISS
N
-
DN
D
S
VD
L
R
N
I
KCP
E
G
S
ERV
G
D
YHTHG
FYS
D
DK
G
NKVTKEN
D
V
Y
D
S
L
N
FSSKD
--
L
T
N
S
YM
N
G
M
G
KKE
C
S
S
YLGTPN
N
T
Y
L
K
Y
N
P
K
A
K
fig|478004.5.peg.2396
Escherichia coli O157:H7 str. EC4401 (956-1382/1394)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
E
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDRTRIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTV
A
QMQ
S
QMDPVYTPARKIHLYHCDHRGLPLALIS
K
EGAT
E
WCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
T
YPL
S
PV
NG
M
DPLGL
YE
-
F
-
--
-
-----
-
-
-
--
-
--
--
---
-
K
SKN
IDD
I
G
I
F
AL
AMC
N
G
ESI
N
E
N
KEY
G
GLICK
-
KQ
GEYF
PMN
P
ISS
N
-
DN
D
S
VD
L
R
N
I
KCP
E
G
S
ERV
G
D
YHTHG
FYS
D
DK
G
NKVTKEN
D
V
Y
D
S
L
N
FSSKD
--
L
T
N
S
YM
N
G
M
G
KKE
C
S
S
YLGTPN
N
T
Y
L
K
Y
N
P
K
A
K
fig|478005.5.peg.2244
Escherichia coli O157:H7 str. EC4486 (956-1382/1394)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
E
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDRTRIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTV
A
QMQ
S
QMDPVYTPARKIHLYHCDHRGLPLALIS
K
EGAT
E
WCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
T
YPL
S
PV
NG
M
DPLGL
YE
-
F
-
--
-
-----
-
-
-
--
-
--
--
---
-
K
SKN
IDD
I
G
I
F
AL
AMC
N
G
ESI
N
E
N
KEY
G
GLICK
-
KQ
GEYF
PMN
P
ISS
N
-
DN
D
S
VD
L
R
N
I
KCP
E
G
S
ERV
G
D
YHTHG
FYS
D
DK
G
NKVTKEN
D
V
Y
D
S
L
N
FSSKD
--
L
T
N
S
YM
N
G
M
G
KKE
C
S
S
YLGTPN
N
T
Y
L
K
Y
N
P
K
A
K
fig|478007.5.peg.2221
Escherichia coli O157:H7 str. EC508 (956-1382/1394)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
E
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDRTRIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTV
A
QMQ
S
QMDPVYTPARKIHLYHCDHRGLPLALIS
K
EGAT
E
WCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
T
YPL
S
PV
NG
M
DPLGL
YE
-
F
-
--
-
-----
-
-
-
--
-
--
--
---
-
K
SKN
IDD
I
G
I
F
AL
AMC
N
G
ESI
N
E
N
KEY
G
GLICK
-
KQ
GEYF
PMN
P
ISS
N
-
DN
D
S
VD
L
R
N
I
KCP
E
G
S
ERV
G
D
YHTHG
FYS
D
DK
G
NKVTKEN
D
V
Y
D
S
L
N
FSSKD
--
L
T
N
S
YM
N
G
M
G
KKE
C
S
S
YLGTPN
N
T
Y
L
K
Y
N
P
K
A
K
fig|544404.4.peg.5072
Escherichia coli O157:H7 str. TW14359 (956-1382/1394)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
E
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDRTRIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTV
A
QMQ
S
QMDPVYTPARKIHLYHCDHRGLPLALIS
K
EGAT
E
WCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
T
YPL
S
PV
NG
M
DPLGL
YE
-
F
-
--
-
-----
-
-
-
--
-
--
--
---
-
K
SKN
IDD
I
G
I
F
AL
AMC
N
G
ESI
N
E
N
KEY
G
GLICK
-
KQ
GEYF
PMN
P
ISS
N
-
DN
D
S
VD
L
R
N
I
KCP
E
G
S
ERV
G
D
YHTHG
FYS
D
DK
G
NKVTKEN
D
V
Y
D
S
L
N
FSSKD
--
L
T
N
S
YM
N
G
M
G
KKE
C
S
S
YLGTPN
N
T
Y
L
K
Y
N
P
K
A
K
fig|566546.4.peg.4232
Escherichia coli W (952-1378/1390)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
A
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDR
S
RIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
T
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQMQ
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
T
EGATAWCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
T
YPL
S
PV
NS
M
DPLGL
YE
-
F
-
--
-
-----
-
-
-
--
-
--
--
---
-
K
SKN
IDD
I
G
I
F
AL
AMC
N
G
ESI
N
E
N
KEY
G
GLICK
-
KQ
GEY
L
PMN
P
ISS
N
-
DN
D
S
VD
L
R
N
I
KCP
E
G
S
ERV
G
D
YHTHG
FYS
D
DK
G
NKVTKEN
D
V
Y
D
S
L
N
FSSKD
--
L
T
N
S
YM
N
G
M
E
KKE
Y
S
S
YLGTPN
N
T
Y
L
K
Y
N
P
K
A
K
fig|573235.3.peg.4775
Escherichia coli O26:H11 str. 11368 (956-1382/1394)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
E
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDR
S
RIQTIYQPGSFTPLIRVET
A
TGE
L
A
R
TQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQMQ
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
K
EG
T
T
E
WCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
T
YPL
S
PV
NS
M
DPLGL
YE
-
F
-
--
-
-----
-
-
-
--
-
--
--
---
-
K
SKN
IDD
I
G
I
F
AL
AMC
N
G
ESI
N
E
N
KEY
G
GLICK
-
KQ
GEYF
PMN
P
ISS
N
-
DN
D
S
VD
L
R
N
I
KCP
E
G
S
ERV
G
D
YHTHG
FYS
D
DK
G
NKVTKEN
D
V
Y
D
S
L
N
FSSKD
--
L
T
N
S
YM
N
G
M
G
KKE
Y
S
S
YLGTPN
N
T
Y
L
K
Y
N
P
K
A
K
fig|585055.6.peg.4446
Escherichia coli 55989 (957-1382/1394)
IRTDDERTHRYHYDSQHRLVHYTRTQY
A
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDR
S
RIQTIYQPGSFTPLIRVET
A
TGE
Q
AKTQRRSLAD
T
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQMQ
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
T
EGATAWCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
T
YPL
S
PV
NS
M
DPLGL
YE
-
F
-
--
-
-----
-
-
-
--
-
--
--
---
-
K
SKN
IDD
I
G
I
F
AL
AMC
N
G
ESI
N
E
N
KEY
G
GLICK
-
KQ
GEY
L
PMN
P
ISS
N
-
DN
D
S
VD
L
R
N
I
KCP
E
G
S
ERV
G
D
YHTHG
FYS
D
DK
G
NKVTKEN
D
V
Y
D
S
L
N
FSSKD
--
L
T
N
S
YM
N
G
M
G
KKE
Y
S
S
YLGTPN
N
T
Y
L
K
Y
N
P
K
A
K
fig|585055.8.peg.4450
Escherichia coli 55989 (957-1382/1394)
IRTDDERTHRYHYDSQHRLVHYTRTQY
A
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDR
S
RIQTIYQPGSFTPLIRVET
A
TGE
Q
AKTQRRSLAD
T
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQMQ
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
T
EGATAWCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
T
YPL
S
PV
NS
M
DPLGL
YE
-
F
-
--
-
-----
-
-
-
--
-
--
--
---
-
K
SKN
IDD
I
G
I
F
AL
AMC
N
G
ESI
N
E
N
KEY
G
GLICK
-
KQ
GEY
L
PMN
P
ISS
N
-
DN
D
S
VD
L
R
N
I
KCP
E
G
S
ERV
G
D
YHTHG
FYS
D
DK
G
NKVTKEN
D
V
Y
D
S
L
N
FSSKD
--
L
T
N
S
YM
N
G
M
G
KKE
Y
S
S
YLGTPN
N
T
Y
L
K
Y
N
P
K
A
K
fig|679206.4.peg.5069
Escherichia coli MS 119-7 (34-460/472)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
A
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDR
S
RIQTIYQPGSFTPLIRVET
A
TGE
L
A
R
TQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLT
L
EQMQ
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
K
EG
T
T
E
WCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
T
YPL
S
PV
NS
M
DPLGL
YE
-
F
-
--
-
-----
-
-
-
--
-
--
--
---
-
K
SKN
IDD
I
G
I
F
AL
AMC
N
G
ESI
N
E
N
KEY
G
GLICK
-
KQ
GEYF
PMN
P
ISS
N
-
DN
D
S
VD
L
R
N
I
KCP
E
G
S
ERV
G
D
YHTHG
FYS
D
DK
G
NKVTKEN
D
V
Y
D
S
L
N
FSSKD
--
L
T
N
S
YM
N
G
M
G
KKE
Y
S
S
YLGTPN
N
T
Y
L
K
Y
N
P
K
A
K
fig|585034.4.peg.4038
Escherichia coli IAI1 (217-643/655)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
E
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDRTRIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
T
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQMQ
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
T
EGATAWCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
T
YPL
S
PV
NS
M
DPLGL
YE
-
F
-
--
-
-----
-
-
-
--
-
--
--
---
-
K
SKN
IDD
I
G
I
F
AL
AMC
N
G
ESI
N
E
N
KEY
G
GLICK
-
KQ
GEY
L
PMN
P
ISS
N
-
DN
D
S
VD
L
R
N
I
KCP
E
G
S
ERV
G
D
YHTHG
FYS
D
DK
G
NKVTKEN
D
V
Y
D
S
L
N
FSSKD
--
L
T
N
S
YM
N
G
M
G
KKE
Y
S
S
YLGTPN
N
T
Y
L
K
Y
N
P
K
A
K
fig|585034.5.peg.4034
Escherichia coli IAI1 (217-643/655)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
E
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDRTRIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
T
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQMQ
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
T
EGATAWCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
T
YPL
S
PV
NS
M
DPLGL
YE
-
F
-
--
-
-----
-
-
-
--
-
--
--
---
-
K
SKN
IDD
I
G
I
F
AL
AMC
N
G
ESI
N
E
N
KEY
G
GLICK
-
KQ
GEY
L
PMN
P
ISS
N
-
DN
D
S
VD
L
R
N
I
KCP
E
G
S
ERV
G
D
YHTHG
FYS
D
DK
G
NKVTKEN
D
V
Y
D
S
L
N
FSSKD
--
L
T
N
S
YM
N
G
M
G
KKE
Y
S
S
YLGTPN
N
T
Y
L
K
Y
N
P
K
A
K
fig|409438.11.peg.4404
Escherichia coli SE11 (936-1362/1374)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
E
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDR
S
RIQTIYQPGSFTPLIRVET
A
TGE
L
A
R
TQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILA
A
RVSEESRRWLASCGLTVEQMQ
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
K
EG
T
T
E
WCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
T
YPL
S
PV
NS
M
DPLGL
YE
-
F
-
--
-
-----
-
-
-
--
-
--
--
---
-
K
SKN
IDD
I
G
I
F
AL
AMC
N
G
ESI
N
E
N
KEY
G
GLICK
-
KQ
GEYF
PMN
P
ISS
N
-
DN
D
S
VD
L
R
N
I
KCP
E
G
S
ERV
G
D
YHTHG
FYS
D
DK
G
NKVTKEN
D
V
Y
D
S
L
N
FSSKD
--
L
T
N
S
YM
N
G
M
G
KKE
Y
S
S
YLGTPN
N
T
Y
L
K
Y
N
P
K
A
K
fig|155864.1.peg.4878
Escherichia coli O157:H7 EDL933 (547-973/985)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
E
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDRTRIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTV
A
QMQ
S
QMDPVYTPARKIHLYHCDHRGLPLALIS
K
EGAT
E
WCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
T
YPL
S
PV
NG
M
DPLGL
YE
-
F
-
--
-
-----
-
-
-
--
-
--
--
---
-
K
SKN
IDD
I
G
I
F
AL
AMC
N
G
ESI
N
E
N
KEY
G
GLICK
-
KQ
GEYF
PMN
P
ISS
N
-
DN
D
S
VD
L
R
N
I
KCP
E
G
S
ERV
G
D
YHTHG
FYS
D
DK
G
NKVTKEN
D
V
Y
D
S
L
N
FSSKD
--
L
T
N
S
YM
N
G
M
G
KKE
C
S
S
YLGTPN
N
T
Y
L
K
Y
N
P
K
A
K
fig|562.375.peg.39
Escherichia coli EC4100B (145-570/582)
IRTDDERTHRYHYDSQHRLVHYTRTQY
A
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDR
S
RIQTIYQPGSFTPLIRVET
A
TGE
L
A
R
TQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQMQ
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
K
EG
T
T
E
WCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
T
YPL
S
PV
NS
M
DPLGL
YE
-
F
-
--
-
-----
-
-
-
--
-
--
--
---
-
K
SKN
IDD
I
G
I
F
AL
AMC
N
G
ESI
N
E
N
KEY
G
GLICK
-
KQ
GEYF
PMN
P
ISS
N
-
DN
D
S
VD
L
R
N
I
KCP
E
G
S
ERV
G
D
YHTHG
FYS
D
DK
G
NKVTKEN
D
V
Y
D
S
L
N
FSSKD
--
L
T
N
S
YM
N
G
M
G
KKE
Y
S
S
YLGTPN
N
T
Y
L
K
Y
N
P
K
A
K
fig|585396.4.peg.4936
Escherichia coli O111:H- str. 11128 (953-1378/1390)
IRTDDERTHRYHYDSQHRLVHYTRTQY
A
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDR
S
RIQTIYQPGSFTPLIRVET
A
TGE
L
A
R
TQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILA
A
RVSEESRRWLASCGLTVEQMQ
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
K
EG
T
T
E
WCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
T
YPL
S
PV
NS
M
DPLGL
YE
-
F
-
--
-
-----
-
-
-
--
-
--
--
---
-
K
SKN
IDD
I
G
I
F
AL
AMC
N
G
ESI
N
E
N
KEY
G
GLICK
-
KQ
GEYF
PMN
P
ISS
N
-
DN
D
S
VD
L
R
N
I
KCP
E
G
S
ERV
G
D
YHTHG
FYS
D
DK
G
NKVTKEN
D
V
Y
D
S
L
N
FSSKD
--
L
T
N
S
YM
N
G
M
G
KKE
Y
S
S
YLGTPN
N
T
Y
L
K
Y
N
P
K
A
K
fig|155864.8.peg.4847
Escherichia coli O157:H7 EDL933 (590-1016/1028)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
E
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDRTRIQ
X
IYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTV
A
QMQ
S
QMDPVYTPARKIHLYHCDHRGLPLALIS
K
EGAT
E
WCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
T
YPL
S
PV
NG
M
DPLGL
YE
-
F
-
--
-
-----
-
-
-
--
-
--
--
---
-
K
SKN
IDD
I
G
I
F
AL
AMC
N
G
ESI
N
E
N
KEY
G
GLICK
-
KQ
GEYF
PMN
P
ISS
N
-
DN
D
S
VD
L
R
N
I
KCP
E
G
S
ERV
G
D
YHTHG
FYS
D
DK
G
NKVTKEN
D
V
Y
D
S
L
N
FSSKD
--
L
T
N
S
YM
N
G
M
G
KKE
C
S
S
YLGTPN
N
T
Y
L
K
Y
N
P
K
A
K
fig|701177.3.peg.4755
Escherichia coli O55:H7 str. CB9615 (956-1382/1394)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
A
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDR
S
RIQTIYQPGSFTPLIRVET
A
TGE
L
AKTQRRSLAD
A
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTV
A
QMQ
S
QMDPVYTPARKIHLYHCDHRGLPLALIS
K
EGAT
E
WCAEYDEWGNLLNEEN
L
HQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
T
YPL
S
PV
NG
M
DPLGL
YE
-
F
-
--
-
-----
-
-
-
--
-
--
--
---
-
K
SKN
IDD
I
G
I
F
AL
AMC
N
G
ESI
N
E
N
KEY
G
GLICK
-
KQ
GEYF
PMN
P
ISS
N
-
DN
D
S
VD
L
R
N
I
KCP
E
G
S
ERV
G
D
YHTHG
FYS
D
DK
G
NKVTKEN
D
V
Y
D
S
L
N
FSSKD
--
L
T
N
S
YM
N
G
M
G
KKE
Y
S
S
YLGTPN
N
T
Y
L
K
Y
N
P
K
A
K
fig|344601.3.peg.3757
Escherichia coli B171 (1-407/419)
M
HYTRTQY
A
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDR
S
RIQTIYQPGSFTPLIRVET
A
TGE
Q
AKTQRRSLAD
T
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQMQ
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
T
EGATAWCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
T
YPL
S
PV
NS
M
DPLGL
YE
-
F
-
--
-
-----
-
-
-
--
-
--
--
---
-
K
SKN
IDD
I
G
I
F
AL
AMC
N
G
ESI
N
E
N
KEY
G
GLICK
-
KQ
GEY
L
PMN
P
ISS
N
-
DN
D
S
VD
L
R
N
I
KCP
E
G
S
ERV
G
D
YHTHG
FYS
D
DK
G
NKVTKEN
D
V
Y
D
S
L
N
FSSKD
--
L
T
N
S
YM
N
G
M
E
KKE
Y
S
S
YLGTPN
N
T
Y
L
K
Y
N
P
K
A
K
fig|344601.5.peg.3932
Escherichia coli B171 (1-407/419)
M
HYTRTQY
A
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDR
S
RIQTIYQPGSFTPLIRVET
A
TGE
Q
AKTQRRSLAD
T
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQMQ
N
QMDPVYTPARKIHLYHCDHRGLPLALIS
T
EGATAWCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
T
YPL
S
PV
NS
M
DPLGL
YE
-
F
-
--
-
-----
-
-
-
--
-
--
--
---
-
K
SKN
IDD
I
G
I
F
AL
AMC
N
G
ESI
N
E
N
KEY
G
GLICK
-
KQ
GEY
L
PMN
P
ISS
N
-
DN
D
S
VD
L
R
N
I
KCP
E
G
S
ERV
G
D
YHTHG
FYS
D
DK
G
NKVTKEN
D
V
Y
D
S
L
N
FSSKD
--
L
T
N
S
YM
N
G
M
E
KKE
Y
S
S
YLGTPN
N
T
Y
L
K
Y
N
P
K
A
K
fig|331111.12.peg.4692
Escherichia coli E24377A (956-1353/1365)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
E
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDR
S
RIQTIYQPGSFTPLIRVET
A
TGE
Q
AKTQRRSLAD
T
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASC
--------
-
--------------------
GLPLALIS
T
EGATAWCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
T
YPL
S
PV
NS
M
DPLGL
YE
-
F
-
--
-
-----
-
-
-
--
-
--
--
---
-
K
SKN
IDD
I
G
I
F
AL
AMC
N
G
ESI
N
E
N
KEY
G
GLICK
-
KQ
GEYF
PMN
P
ISS
N
-
DN
D
S
VD
L
R
N
I
KCP
E
G
S
ERV
G
D
YHTHG
FYS
D
DK
G
NKVTKEN
D
V
Y
D
S
L
N
FSSKD
--
L
T
N
S
YM
N
G
M
G
KKE
Y
S
S
YLGTPN
N
T
Y
L
K
Y
N
P
K
A
K
fig|331111.3.peg.2089
Escherichia coli E24377A (956-1353/1365)
VIRTDDERTHRYHYDSQHRLVHYTRTQY
E
EPLVESRYLYDPLGRR
V
AKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDR
S
RIQTIYQPGSFTPLIRVET
A
TGE
Q
AKTQRRSLAD
T
LQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASC
--------
-
--------------------
GLPLALIS
T
EGATAWCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLY
T
YPL
S
PV
NS
M
DPLGL
YE
-
F
-
--
-
-----
-
-
-
--
-
--
--
---
-
K
SKN
IDD
I
G
I
F
AL
AMC
N
G
ESI
N
E
N
KEY
G
GLICK
-
KQ
GEYF
PMN
P
ISS
N
-
DN
D
S
VD
L
R
N
I
KCP
E
G
S
ERV
G
D
YHTHG
FYS
D
DK
G
NKVTKEN
D
V
Y
D
S
L
N
FSSKD
--
L
T
N
S
YM
N
G
M
G
KKE
Y
S
S
YLGTPN
N
T
Y
L
K
Y
N
P
K
A
K
Consen1
Primary consensus
VIRTDDERTHrYHYDSqHRLVhYtRtQy
EPLVESRYLYDPLGRR
aKRVWRRERDLTGWMSLSRKPqVTWYGWDGDRLTTiQnDrtRIQTiYqPGSFtPLIRvET
tGE
aktQRRSLAd
LQQsGgEdGgsVVFPpvLVqmLDRLEsEIlADRVSeESRrWLAsCGLTVeQmq
QmdPvYTPARKiHLYHCDHRGLPLALIS
eGaTaWcAEYDEWGNlLNEENPHqlqQliRLPGQQyDEESGLYYNRHRYYDPLQGRYITQDPiGLKGGWNLY
YpLnPv
iDPlGL
-
w
da
sgact
g
cg
ls
igp
Kfdsidd
a
dAL
n
eSicedkEy
GliCKd
GeYF
p
n
-
rk
Sypl
-
n
kCP
GterV
aYHTHG
--
aDshG
-------
dy
De
-
FSskD
lv
SkdNnm
---
sfYLgTPng
f
a
nnkgkeItNRKG
Consen2
Secondary consensus
h
l
f
i
i
h
g
e
v
t
ts
v
e
a
i
n
era
e
e
s
n
hg
ae
rl
e
r
s
a
q
a
la
ve
e
a
d
n
e
s
q
hvy
py
h
m
q
s
m
m
tf
--
-----
-
--
--
---
skntas
g
f
q
lnnnm
f
iv
-
a
eldn
vdfrk
p
sdk
d
fys
dk
nkvtkenev
s
n
gs
it
ym
g
kke
as
a
n
y
k
dphaey
f
Consensus 1
(when a gap)
Conservative difference
Consensus 2
(when a gap)
Nonconservative diff.
Other character