┌─ Escherichia coli (337-1123/1128) 536   
                                                               ├─ Escherichia coli (349-1135/1140) F11   
                                                               ├─ Escherichia coli (337-1123/1128) IAI39   
                                                               ├─ Escherichia coli (337-1123/1128) MS 200-1   
                                                               ├─ Escherichia coli (337-1123/1128) UM146   
┌──────────────────────────────────────────────────────────────┼─ Escherichia coli (337-1123/1128) UTI89   
│                                                              ├─ Escherichia coli (337-1123/1128) UTI89   
│                                                              ├─ Escherichia coli (337-1123/1128) MS 69-1   
│                                                              ├─ Escherichia coli (337-1123/1128) IAI39   
│                                                              ├─ Escherichia coli (337-1123/1128) F11   
│                                                              └─ Escherichia coli (337-1123/1128) 536   
│                                                                            ┌─ Escherichia coli BW2952   
│                                                                            ├─ Escherichia coli K12   
│                                                                            ├─ Escherichia coli str. K-12 substr. DH10B   
│                                                                            ├─ Escherichia coli str. K-12 substr. MG1655   
│                                                                           ┌┼─ Escherichia coli str. K-12 substr. MG1655   
│                                                                           │├─ Escherichia coli str. K-12 substr. DH10B   
│                                                                           │├─ Escherichia coli W3110   
│                                                                           │└─ Escherichia coli DH1   
│                                                                          ┌┤┌─ Escherichia coli H736   
│                                                                          ││├─ Escherichia coli MS 116-1   
│                                                                          ││├─ Escherichia coli MS 175-1   
│                                                                          │└┼─ Escherichia coli MS 196-1   
│                                                                          │ ├─ Escherichia coli MS 146-1   
│                                                                         ┌┤ ├─ Escherichia coli MS 115-1   
│                                                                         ││ └─ Escherichia coli ETEC H10407   
│                                                                         ││┌─ Escherichia coli B str. REL606   
│                                                                         ││├─ Escherichia coli (DE3) BL21(DE3)   
│                                                                         │└┼─ Escherichia coli MS 187-1   
│                                                                         │ ├─ Escherichia coli BL21   
│                                                                         │ └─ Escherichia coli 101-1   
│                                                                        ┌┤  ┌─ Escherichia coli FVEC1302   
│                                                                        ││  ├─ Escherichia coli H299   
│                                                                        ││ ┌┼─ Escherichia coli UMN026   
│                                                                        ││ │├─ Escherichia coli MS 198-1   
│                                                                        ││┌┤└─ Escherichia coli FVEC1412   
│                                                                        │││└┬─ Escherichia coli 042   
│                                                                        │└┤ └─ Escherichia coli 042   
│                                                                        │ │┌─ Escherichia coli TA143   
│                                                                        │ └┤┌─ Escherichia coli MS 21-1   
│                                                                        │  └┤ ┌─ Escherichia coli O55:H7 str. CB9615   
│                                                                        │   │┌┴─ Escherichia coli O157:H7 EDL933   
│                                                                       ┌┤   └┤┌─ Escherichia coli B185   
│                                                                       ││    ││  ┌─ Escherichia coli ATCC 8739   
│                                                                       ││    └┤ ┌┴─ Escherichia coli ATCC 8739   
│                                                                       ││     │┌┴─ Escherichia coli M718   
│                                                                       ││     └┤┌─ Escherichia coli HS   
│                                                                       ││      └┼─ Escherichia coli HS   
│                                                                       ││       └─ Escherichia coli 1827-70   
│                                                                       ││  ┌─ Escherichia coli E110019   
│                                                                       ││ ┌┴─ Escherichia coli E110019   
│                                                                       ││┌┴─ Escherichia coli MS 145-7   
│                                                                       │││ ┌─ Escherichia coli E24377A   
│                                                                       │└┤┌┴─ Escherichia coli E24377A   
│                                                                       │ ││ ┌─ fig|1040638.4.peg.4666 O104:H4 str. LB226692   
│                                                                       │ ││┌┴─ fig|6666666.5357.peg.3784 TY-2482 strain   
│                                                                       │ └┤│ ┌─ Escherichia coli 53638   
│                                                                       │  ││┌┴─ Escherichia coli 53638   
│                                                                       │  │││┌─ Escherichia coli 55989   
│                                                                       │  └┤│├─ Escherichia coli B171   
│                                                                       │   ││├─ Escherichia coli B354   
│                                                                       │   ││├─ Escherichia coli B7A   
│                                                                       │   ││├─ Escherichia coli E22   
│                                                                       │   ││├─ Escherichia coli H591   
┤                                                                      ┌┤   └┤├─ Escherichia coli IAI1   
│                                                                      ││    │├─ Escherichia coli MS 119-7   
│                                                                      ││    │├─ Escherichia coli MS 182-1   
│                                                                      ││    │├─ Escherichia coli MS 84-1   
│                                                                      ││    │├─ Escherichia coli O111:H- str. 11128   
│                                                                      ││    │├─ Escherichia coli SE11   
│                                                                      ││    │├─ Escherichia coli W   
│                                                                      ││    └┼─ Escherichia coli W   
│                                                                      ││     ├─ Escherichia coli TA271   
│                                                                      ││     ├─ Escherichia coli O26:H11 str. 11368   
│                                                                      ││     ├─ Escherichia coli O103:H2 str. 12009   
│                                                                      ││     ├─ Escherichia coli MS 78-1   
│                                                                      ││     ├─ Escherichia coli MS 124-1   
│                                                                     ┌┤│     ├─ Escherichia coli KO11   
│                                                                     │││     ├─ Escherichia coli IAI1   
│                                                                     │││     ├─ Escherichia coli EC4100B   
│                                                                     │││     ├─ Escherichia coli E22   
│                                                                     │││     ├─ Escherichia coli B7A   
│                                                                     │││     ├─ Escherichia coli B171   
│                                                                     │││     ├─ Escherichia coli B088   
│                                                                     │││     └─ Escherichia coli 55989   
│                                                                    ┌┤│└┬─ Escherichia coli MS 69-1   
│                                                                    │││ └┬─ Escherichia coli TA280   
│                                                                    │││  └┬─ Escherichia coli 2362-75   
│                                                                    │││   └┬─ Escherichia coli O127:H6 str. E2348/69   
│                                                                    │││    └─ Escherichia coli E2348/69   
│                                                                    ││└┬─ Escherichia coli IAI39   
│                                                                    ││ └─ Escherichia coli IAI39   
│                                                                   ┌┤└┬─ Escherichia coli WV_060327   
│                                                                   ││ └─ Escherichia coli O83:H1 str. NRG 857C   
│                                                                   ││ ┌─ Escherichia coli SMS-3-5   
│                                                                   ││┌┴─ Escherichia coli M605   
│                                                                   │││ ┌─ Escherichia coli CFT073   
│                                                                   │││┌┴─ Escherichia coli CFT073   
│                                                                   │└┤│  ┌─ Escherichia coli 536   
│                                                                   │ ││  ├─ Escherichia coli F11   
│                                                                   │ ││ ┌┼─ Escherichia coli MS 200-1   
│                                                                   │ └┤ │├─ Escherichia coli F11   
│                                                                   │  │┌┤└─ Escherichia coli 536   
│                                                                   │  ││└┬─ Escherichia coli ED1a   
│                                                                   │  ││ └─ Escherichia coli ED1a   
│                                                                  ┌┤  └┤┌─ Escherichia coli TA206   
│                                                                  ││   ││┌─ Escherichia coli ABU 83972   
│                                                                  ││   ││├─ Escherichia coli APEC O1   
│                                                                  ││   └┤├─ Escherichia coli MS 185-1   
│                                                                  ││    │├─ Escherichia coli NC101   
│                                                                  ││    │├─ Escherichia coli UM146   
│                                                                  ││    └┼─ Escherichia coli UTI89   
│        ┌─────────────────────────────────────────────────────────┤│     ├─ Escherichia coli UTI89   
│        │                                                         ││     ├─ Escherichia coli S88   
│        │                                                         ││     ├─ Escherichia coli MS 45-1   
│        │                                                         ││     ├─ Escherichia coli IHE3034   
│        │                                                         ││     ├─ Escherichia coli APEC O1   
│        │                                                         ││     └─ Escherichia coli 83972   
│        │                                                         │└─ Escherichia coli MS 107-1   
│        │                                                         └─ Escherichia coli SE15   
│        │                                                           ┌─ Escherichia coli (1-831/832) 101-1   
│        │                                                           ├─ Escherichia coli (1-831/832) CFT073   
│        │                                                           ├─ Escherichia coli (1-831/832) ED1a   
└────────┤                                                          ┌┼─ Escherichia coli (1-831/832) S88   
         │                                                          │├─ Escherichia coli (1-831/832) ED1a   
         │                                                         ┌┤└─ Escherichia coli (1-831/832) APEC O1   
         │                                                         ││┌─ Escherichia coli (10-849/850) CFT073   
         │        ┌────────────────────────────────────────────────┤└┼─ Escherichia coli (10-849/850) MS 116-1   
         │        │                                                │ └─ Escherichia coli (10-849/850) APEC O1   
         │        │                                                └─ Escherichia coli (1-831/832) MS 21-1   
         │        │                                        ┌─ Escherichia coli WV_060327   
         │        │                                        │     ┌─ Escherichia coli 83972   
         │        │                                        │     ├─ Escherichia coli CFT073   
         │        │                                        │     ├─ Escherichia coli ED1a   
         │        │                                        │     ├─ Escherichia coli MS 185-1   
         └────────┤                                        │     ├─ Escherichia coli NC101   
                  │                                        │    ┌┼─ Escherichia coli O83:H1 str. NRG 857C   
                  │                                        │    │├─ Escherichia coli MS 45-1   
                  │                                        │    │├─ Escherichia coli ED1a   
                  │                                        │   ┌┤├─ Escherichia coli CFT073   
                  │                                        │   ││└─ Escherichia coli ABU 83972   
                  │                                        │   ││┌─ Escherichia coli E2348/69   
                  │                                        │  ┌┤└┼─ Escherichia coli O127:H6 str. E2348/69   
                  └────────────────────────────────────────┤  ││ └─ Escherichia coli 2362-75   
                                                           │  ││┌─ Escherichia coli SE15   
                                                           │  │└┤┌─ Escherichia coli 536   
                                                           │  │ │├─ Escherichia coli F11   
                                                           │ ┌┤ └┼─ Escherichia coli MS 200-1   
                                                           │ ││  ├─ Escherichia coli F11   
                                                           │ ││  └─ Escherichia coli 536   
                                                           │ ││┌─ Escherichia coli TA206   
                                                           │ │││┌─ Escherichia coli APEC O1   
                                                           │ │└┤├─ Escherichia coli S88   
                                                           │┌┤ │├─ Escherichia coli UTI89   
                                                           │││ └┼─ Escherichia coli UTI89   
                                                           │││  ├─ Escherichia coli UM146   
                                                           │││  ├─ Escherichia coli IHE3034   
                                                           └┤│  └─ Escherichia coli APEC O1   
                                                            │└─ Escherichia coli H299   
                                                            │┌─ Escherichia coli SMS-3-5   
                                                            ││┌─ Escherichia coli B354   
                                                            │││┌─ Escherichia coli B185   
                                                            └┤││  ┌─ Escherichia coli 1044A   
                                                             │││  ├─ Escherichia coli 1212A   
                                                             │││  ├─ Escherichia coli O157:H7   
                                                             │││  ├─ Escherichia coli O157:H7 EDL933   
                                                             └┤│  ├─ Escherichia coli O157:H7 str. EC4042   
                                                              ││  ├─ Escherichia coli O157:H7 str. EC4076   
                                                              ││  ├─ Escherichia coli O157:H7 str. EC4115   
                                                              ││  ├─ Escherichia coli O157:H7 str. EC4206   
                                                              ││  ├─ Escherichia coli O157:H7 str. EC4486   
                                                              ││  ├─ Escherichia coli O157:H7 str. EC508   
                                                              ││  ├─ Escherichia coli O157:H7 str. FRIK2000   
                                                              └┤  ├─ Escherichia coli O157:H7 str. Sakai   
                                                               │ ┌┼─ Escherichia coli O157:H7 str. TW14588   
                                                               │ │├─ Escherichia coli O157:H7 str. TW14359   
                                                               │ │├─ Escherichia coli O157:H7 str. FRIK966   
                                                               │ │├─ Escherichia coli O157:H7 str. EC869   
                                                               │ │├─ Escherichia coli O157:H7 str. EC4501   
                                                               │ │├─ Escherichia coli O157:H7 str. EC4401   
                                                               │ │├─ Escherichia coli O157:H7 str. EC4196   
                                                               │┌┤├─ Escherichia coli O157:H7 str. EC4113   
                                                               │││├─ Escherichia coli O157:H7 str. EC4045   
                                                               │││├─ Escherichia coli O157:H7 str. EC4024   
                                                               │││├─ Escherichia coli O157:H7 EDL933   
                                                               │││├─ Escherichia coli 536A   
                                                               └┤│└─ Escherichia coli 1125A   
                                                                │└─ Escherichia coli O55:H7 str. CB9615   
                                                                │ ┌─ Escherichia coli 042   
                                                                │┌┴─ Escherichia coli 042   
                                                                ││┌─ Escherichia coli MS 69-1   
                                                                └┤│ ┌─ Escherichia coli M605   
                                                                 ││┌┴─ Escherichia coli M718   
                                                                 └┤│┌─ Escherichia coli TA143   
                                                                  │││┌─ Escherichia coli SE11   
                                                                  ││││    ┌─ Escherichia coli B7A   
                                                                  └┤││    ├─ Escherichia coli E22   
                                                                   │││    ├─ Escherichia coli IAI1   
                                                                   │││    ├─ Escherichia coli KO11   
                                                                   │││    ├─ Escherichia coli MS 145-7   
                                                                   └┤│    ├─ Escherichia coli O103:H2 str. 12009   
                                                                    ││   ┌┼─ Escherichia coli W   
                                                                    ││   │├─ Escherichia coli W   
                                                                    ││   │├─ Escherichia coli MS 84-1   
                                                                    ││   │├─ Escherichia coli MS 124-1   
                                                                    ││  ┌┤├─ Escherichia coli IAI1   
                                                                    ││  ││├─ Escherichia coli E22   
                                                                    └┤  ││└─ Escherichia coli B7A   
                                                                     │  │└┬─ Escherichia coli EC4100B   
                                                                     │ ┌┤ └┬─ Escherichia coli E110019   
                                                                     │ ││  └─ Escherichia coli E110019   
                                                                     │ ││ ┌─ Escherichia coli B171   
                                                                     │ ││┌┴─ Escherichia coli B171   
                                                                     │┌┤└┤┌─ Escherichia coli MS 119-7   
                                                                     │││ └┼─ Escherichia coli TA271   
                                                                     │││  └─ Escherichia coli H591   
                                                                     ││└┬─ Escherichia coli O26:H11 str. 11368   
                                                                     ││ └─ Escherichia coli O111:H- str. 11128   
                                                                     ││  ┌─ Escherichia coli FVEC1302   
                                                                     ││  ├─ Escherichia coli MS 198-1   
                                                                     └┤ ┌┼─ Escherichia coli UMN026   
                                                                      │ │├─ Escherichia coli TA280   
                                                                      │┌┤└─ Escherichia coli FVEC1412   
                                                                      ││└┬─ Escherichia coli MS 21-1   
                                                                      ││ └┬─ Escherichia coli IAI39   
                                                                      ││  └─ Escherichia coli IAI39   
                                                                      ││┌─ Escherichia coli ETEC H10407   
                                                                      └┤│  ┌─ fig|1040638.4.peg.1374 O104:H4 str. LB226692   
                                                                       ││  ├─ Escherichia coli 55989   
                                                                       ││  ├─ Escherichia coli E24377A   
                                                                       ││  ├─ Escherichia coli MS 182-1   
                                                                       ││ ┌┼─ Escherichia coli MS 78-1   
                                                                       ││ │├─ Escherichia coli E24377A   
                                                                       └┤┌┤├─ Escherichia coli 55989   
                                                                        │││└─ fig|6666666.5357.peg.4292 TY-2482 strain   
                                                                        ││└─ Escherichia coli MS 107-1   
                                                                        ││  ┌─ Escherichia coli BW2952   
                                                                        ││  ├─ Escherichia coli K12   
                                                                        ││  ├─ Escherichia coli MS 175-1   
                                                                        ││  ├─ Escherichia coli W3110   
                                                                        ││  ├─ Escherichia coli str. K-12 substr. DH10B   
                                                                        └┤ ┌┼─ Escherichia coli str. K-12 substr. MG1655   
                                                                         │ │├─ Escherichia coli str. K-12 substr. MG1655   
                                                                         │ │├─ Escherichia coli str. K-12 substr. DH10B   
                                                                         │┌┤├─ Escherichia coli MS 196-1   
                                                                         │││├─ Escherichia coli MS 116-1   
                                                                         │││└─ Escherichia coli DH1   
                                                                         ││└┬─ Escherichia coli MS 146-1   
                                                                         ││ └─ Escherichia coli H736   
                                                                         └┤  ┌─ Escherichia coli 1827-70   
                                                                          │ ┌┼─ Escherichia coli 53638   
                                                                          │┌┤└─ Escherichia coli 53638   
                                                                          ││└┬─ Escherichia coli B088   
                                                                          ││ └─ Escherichia coli MS 115-1   
                                                                          └┤┌─ Escherichia coli ATCC 8739   
                                                                           │├─ Escherichia coli B str. REL606   
                                                                           │├─ Escherichia coli (DE3) BL21(DE3)   
                                                                           │├─ Escherichia coli HS   
                                                                           └┼─ Escherichia coli MS 187-1   
                                                                            ├─ Escherichia coli HS   
                                                                            ├─ Escherichia coli BL21   
                                                                            ├─ Escherichia coli ATCC 8739   
                                                                            └─ Escherichia coli 101-1   
  
Pyruvate formate-lyase (EC 2.3.1.54) (259)
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