┬───────────────────────────────────────────────────────────────── Escherichia coli (206-397/400) B171   
└───────────────────────────────────────────────────────────────┬─ Escherichia coli MS 45-1   
                                                                └┬─ Escherichia coli 536 (24)  
                                                                 └┬─── Escherichia coli (1-177/193) O157:H7 str. EC4024   
                                                                  └─ Escherichia coli K12 (102)  
  

  
GTP cyclohydrolase II (EC 3.5.4.25)
 (4)
  
3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II (EC 3.5.4.25)
 (1)