┌─ Escherichia coli (40-255/260) WV_060327 ┌┴─ Escherichia coli (40-255/260) IAI39 (1) ┌┴─ fig|1040638.4.peg.3503 O104:H4 (40-255/260) str. LB226692 (11) ┌┴┬─ Escherichia coli (40-255/260) SE15 ┌┤ └─ Escherichia coli (40-255/260) 536 (14) ┌┤└─ Escherichia coli (40-255/260) 101-1 (69) │└┬─ Escherichia coli (40-255/260) TA206 ┌┤ └┬─ Escherichia coli (19-234/239) M718 ││ └─ Escherichia coli (19-234/239) K12 (8) ┌─────────────────────┤└┬─ Escherichia coli (40-255/260) EC4100B (4) │ │ └─ Escherichia coli (40-255/260) 042 (10) │ └┬─ Escherichia coli (40-255/260) 2362-75 (2) │ └┬─ Escherichia coli (40-255/260) B354 ┌─┤ └─ Escherichia coli (40-255/260) H736 │ │ ┌─ Escherichia coli (3-221/226) ATCC 8739 (1) │ │ ┌┴─ Escherichia coli (3-221/226) ETEC H10407 │ │ ┌┴─ fig|1040638.4.peg.2102 O104:H4 (3-221/226) str. LB226692 (5) │ └───────┬──┴─ Escherichia coli (3-221/226) MS 115-1 ┌──────────────┤ └─┬─ Escherichia coli (3-221/227) 2362-75 │ │ └┬─ Escherichia coli (3-221/227) K12 (113) │ │ └┬─ Escherichia coli (3-221/227) O111:H- str. 11128 │ │ └─ Escherichia coli (3-221/227) 101-1 (15) │ └──────────── fig|1040638.4.peg.2084 O104:H4 (1-221/226) str. LB226692 (9) │ ┌─ Escherichia coli (3-216/222) 1125A │ ┌┴─ Escherichia coli (3-216/222) K12 (8) ┌────────────────┤ ┌┴┬─ Escherichia coli (3-216/222) B str. REL606 │ │ ┌┤ └─ Escherichia coli (3-216/222) MS 115-1 │ │ ┌┤└─ fig|1040638.4.peg.1159 O104:H4 (3-216/222) str. LB226692 (89) │ │ ┌┤└─ Escherichia coli (3-216/222) IAI39 (4) │ │ ┌──────────────────────────┤└─ Escherichia coli (3-216/222) 042 (3) │ │ │ └─ Escherichia coli (3-216/222) 2362-75 (21) │ │ │ ┌─ Escherichia coli (3-210/215) E24377A (1) │ └────────┤ ┌┴─ Escherichia coli (3-205/210) O157:H7 str. EC4486 │ │ ┌┴─ fig|6666666.5357.peg.2248 TY-2482 (3-214/219) strain (50) │ │ ┌┴┬─ Escherichia coli (3-214/219) B185 │ │ │ └─ Escherichia coli (3-214/219) O157:H7 EDL933 │ └────────────────────┤ ┌─ Escherichia coli (3-214/219) SE15 │ │┌┴─ Escherichia coli (3-214/219) TA280 │ ││ ┌─ Escherichia coli (3-214/219) E2348/69 (1) │ └┤ ┌┴─ Escherichia coli (3-214/219) 2362-75 │ │┌┴─ Escherichia coli (3-214/219) MS 124-1 (1) │ └┤┌─ Escherichia coli (3-214/219) HS (1) │ └┤ ┌─ Escherichia coli (3-214/219) K12 (6) │ └┬┴─ Escherichia coli (3-205/210) str. K-12 substr. DH10B │ └┬─ Escherichia coli (3-214/219) 042 (48) │ └─ Escherichia coli (3-214/219) 83972 (5) │ ┌─ Escherichia coli B7A (16) │ ┌┴─ Escherichia coli B171 (1) ┤ ┌┴─ Escherichia coli (4-242/242) K12 (37) │ ┌┴┬─ Escherichia coli 1044A (23) │ ┌┤ └─ Escherichia coli MS 146-1 │ │└┬─ Escherichia coli H299 (2) │ │ └┬─ Escherichia coli 2362-75 (18) │ ┌┤ └┬─ Escherichia coli APEC O1 (9) │ ││ └─ Escherichia coli WV_060327 │ ┌┤└─ fig|1040638.4.peg.3655 O104:H4 str. LB226692 (7) │ │└┬─ Escherichia coli 042 (1) │ ┌────────────────────────────────────────┤ └─ Escherichia coli MS 21-1 │ ┌┤ └─ Escherichia coli MS 119-7 (1) │ │└───────────────────────────┬─ Escherichia coli (1-227/232) APEC O1 │ ┌───┤ └┬─ Escherichia coli (1-227/232) CFT073 (2) │ │ │ └─ Escherichia coli (1-227/232) K12 (19) │ │ └───────────────────────────┬── Escherichia coli (7-240/240) MS 185-1 │ │ └─────┬─ Escherichia coli (7-232/239) 536 (1) │ │ └┬─ Escherichia coli (8-233/240) F11 (7) │ │ └┬─ Escherichia coli (7-232/239) 83972 (1) │ │ └─ Escherichia coli (8-233/240) CFT073 (2) │ │ ┌─ Escherichia coli (7-234/239) MS 146-1 │ │ ┌┴─ Escherichia coli (DE3 7-234/239) BL21(DE3) │ │ ┌┴─ Escherichia coli (7-234/239) K12 (131) │ │ ┌────────────────────────────┴─ Escherichia coli (7-234/239) B str. REL606 └───┤ │ ┌─ Escherichia coli (5-224/229) MS 69-1 │ │ ┌┴─ Escherichia coli (5-224/229) TA280 │ │ ┌┴─ Escherichia coli (5-224/229) H299 │ │ ┌┴─ Escherichia coli (5-224/229) K12 (7) │ │ ┌┴─ Escherichia coli (5-224/229) B354 (1) │ │ ┌┤ ┌─ Escherichia coli (5-224/229) 2362-75 (26) │ │ │└┬┴─ Escherichia coli (5-224/229) M605 │ │ ┌┤ └┬─ Escherichia coli (5-224/229) O55:H7 str. CB9615 │ │ ││ └─ Escherichia coli (5-224/229) 1044A (23) │ │ ┌┤└─ Escherichia coli (5-224/229) FVEC1302 (10) │ │ │└┬─ Escherichia coli (5-224/229) E22 (8) │ │ │ └┬─ Escherichia coli (5-224/229) B171 (1) └─┤ ┌┤ └┬─ Escherichia coli (5-224/229) E24377A (1) │ ││ └┬─ fig|1040638.4.peg.817 O104:H4 (5-224/229) str. LB226692 (22) │ ┌──────────────────────────┤│ └─ Escherichia coli (5-224/229) MS 107-1 │ │ │└─ Escherichia coli (5-224/229) ATCC 8739 (10) │ │ └─ Escherichia coli (5-224/229) 042 (5) │ ┌───────────┤ ┌─ Escherichia coli (13-230/240) O157:H7 EDL933 (1) │ │ │ ┌┴─ Escherichia coli (13-230/240) 1044A (22) │ │ └────────────────────┤┌─ Escherichia coli (13-230/240) IAI39 (2) │ │ └┤┌─ Escherichia coli (13-230/240) ATCC 8739 (1) │ │ └┤ ┌─ Escherichia coli (13-237/240) 101-1 │ │ └┬┴─ Escherichia coli (13-230/240) K12 (70) │ │ └┬─ Escherichia coli (13-230/240) TA280 │ │ └┬─ Escherichia coli (13-230/240) MS 185-1 └────┤ └┬─ Escherichia coli (13-230/240) MS 115-1 │ └┬─ fig|1040638.4.peg.3161 O104:H4 (13-230/240) str. LB226692 (22) │ └┬─ Escherichia coli (13-230/240) MS 182-1 (1) │ └─ Escherichia coli (13-230/240) EC4100B (3) │ ┌─ Escherichia coli (5-231/235) 1044A (24) │ ┌──────────────────────────────────┴─ Escherichia coli (14-237/241) O157:H7 EDL933 (1) │ │ ┌─ Escherichia coli (5-226/229) CFT073 (1) │ │ ┌┴─ Escherichia coli (5-226/229) TA206 │ │ ┌┴─ Escherichia coli (5-226/229) K12 (125) └──┤ ┌───────────────────────┴─ Escherichia coli (5-226/229) MS 107-1 │ ┌┴───────────────────────────────────────────┬─ Escherichia coli (6-232/238) B str. REL606 │ │ └─ Escherichia coli (6-232/238) K12 (131) │ │ ┌─ Escherichia coli (11-220/223) 042 (1) │ │ ┌┴─ Escherichia coli (3-220/223) E110019 (1) └─┤ ┌┴─ fig|1040638.4.peg.4458 O104:H4 (3-220/223) str. LB226692 (73) │ ┌┴─ Escherichia coli (3-220/223) 1044A (25) │ ┌┴─ Escherichia coli (3-220/223) 2362-75 (2) │ ┌───────────────────────────────────────┴─ Escherichia coli (3-220/223) K12 (23) └───────────┤ ┌─ Escherichia coli (1-223/225) B185 └─────────────────────────┤ ┌─ Escherichia coli (1-223/225) O157:H7 EDL933 │┌┴─ Escherichia coli (1-223/225) 1044A (25) └┤ ┌─ fig|1040638.4.peg.5040 O104:H4 str. LB226692 (31) │┌┴─ Escherichia coli 55989 (1) └┤┌─ Escherichia coli (1-223/225) 042 (4) └┤ ┌─ Escherichia coli SE15 │┌┴─ Escherichia coli (1-223/225) 2362-75 (3) └┤ ┌─ Escherichia coli IHE3034 (3) │ ┌┴─ Escherichia coli (1-223/225) FVEC1302 (3) └┬┴─ Escherichia coli 536 (20) └┬─ Escherichia coli (1-223/225) B354 (1) └┬─ Escherichia coli (1-223/225) K12 (20) └┬─ Escherichia coli (1-223/225) ATCC 8739 (1) └─ Escherichia coli (1-223/225) 101-1 (4)
| Two-component response regulator CreB | (16) |
| Two-component system response regulator QseB | (14) |
| DNA-binding response regulator KdpE | (14) |
| Putative two-component system response regulator YedW | (13) |
| Transcriptional regulatory protein RstA | (12) |
| Response regulator BaeR | (11) |
| Transcriptional regulatory protein basR/pmrA | (7) |
| Copper-sensing two-component system response regulator CusR | (7) |
| Transcriptional regulatory protein PhoP | (5) |
| Phosphate regulon transcriptional regulatory protein PhoB (SphR) | (4) |
| Two-component system response regulator OmpR | (4) |
| Copper-sensing two-component system response regulator CpxR | (3) |
| Putative response regulator | (3) |
| Aerobic respiration control protein arcA | (2) |
| Putative response regulator protein | (2) |
| Transcriptional regulatory protein ompR | (1) |
| putative response regulator | (1) |
| Others | (10) |