fig|1040638.4.peg.359
Escherichia coli O104:H4 str. LB226692
MYGR
R
T
L
V
D
D
SG
N
-
--
KA
LR
I
E
K
-
N
N
---
S
AK
SW
S
M
Y
C
D
I
A
A
D
K
A
K
L
LL
E
KGG
E
I
A
V
RFK
I
P
E
N
V
N
L
ET
T
R
N
K
Y
A
F
GL
Y
-
W
R
IA
EW
P
--
-
-
-
-
G
E
GG
EGH
L
S
S
F
F
V
QTD
KAS
I
NV
AY
H
H
TV
N
--
-Q
Q
K
E
LGTFGAFD
H
D
WHTLAF
K
F
K
G
S
NS
I
N
VTPV
L
DG
V
DG
Q
A
F
D
L
V
KW
A
N
TA
N
G
L
NR
F
V
I
TDIT
GS
A
E
TYPVLID
T
V
E
V
K
A
N
K
AG
A
AA
fig|6666666.5357.peg.2116
Escherichia coli TY-2482
MYGR
R
T
L
V
D
D
SG
N
-
--
KA
LR
I
E
K
-
N
N
---
S
AK
SW
S
M
Y
C
D
I
A
A
D
K
A
K
L
LL
E
KGG
E
I
A
V
RFK
I
P
E
N
V
N
L
ET
T
R
N
K
Y
A
F
GL
Y
-
W
R
IA
EW
P
--
-
-
-
-
G
E
GG
EGH
L
S
S
F
F
V
QTD
KAS
I
NV
AY
H
H
TV
N
--
-Q
Q
K
E
LGTFGAFD
H
D
WHTLAF
K
F
K
G
S
NS
I
N
VTPV
L
DG
V
DG
Q
A
F
D
L
V
KW
A
N
TA
N
G
L
NR
F
V
I
TDIT
GS
A
E
TYPVLID
T
V
E
V
K
A
N
K
AG
A
AA
fig|585397.7.peg.1435
Escherichia coli ED1a (471-662/662)
G
K
G
T
V
TD
D
G
G
R
-
--
KA
LR
L
E
K
Q
P
G
---
K
LT
SW
K
M
F
CT
V
A
V
E
E
A
K
N
LL
S
KGG
E
I
A
V
RFK
I
P
D
G
S
EL
--
V
N
G
Q
F
V
F
GL
Y
-
WPVS
Q
WA
--
-
-
-
S
G
A
A
A
N
SM
LA
S
F
F
L
QTDA
S
N
LN
L
-
M
H
H
KG
T
--
-S
N
A
Q
LGTFGAFD
HN
WHT
V
V
FRFAGNNS
E
R
V
V
PVIDG
T
E
Q
T
A
F
D
L
V
M
W
T
N
DG
F
T
AD
T
L
T
L
TDIT
GA
K
A
TYPVL
L
D
T
V
T
V
K
VN
E
S
RA
SS
fig|585397.9.peg.1428
Escherichia coli ED1a (471-662/662)
G
K
G
T
V
TD
D
G
G
R
-
--
KA
LR
L
E
K
Q
P
G
---
K
LT
SW
K
M
F
CT
V
A
V
E
E
A
K
N
LL
S
KGG
E
I
A
V
RFK
I
P
D
G
S
EL
--
V
N
G
Q
F
V
F
GL
Y
-
WPVS
Q
WA
--
-
-
-
S
G
A
A
A
N
SM
LA
S
F
F
L
QTDA
S
N
LN
L
-
M
H
H
KG
T
--
-S
N
A
Q
LGTFGAFD
HN
WHT
V
V
FRFAGNNS
E
R
V
V
PVIDG
T
E
Q
T
A
F
D
L
V
M
W
T
N
DG
F
T
AD
T
L
T
L
TDIT
GA
K
A
TYPVL
L
D
T
V
T
V
K
VN
E
S
RA
SS
fig|585397.7.peg.1125
Escherichia coli ED1a (462-657/657)
K
N
T
L
VSD
SG
S
-
G
K
KA
LR
L
E
K
P
E
NGLA
Q
KK
T
W
K
V
S
H
A
IDA
G
KG
K
E
L
FDN
GG
E
I
T
L
RFK
I
P
D
D
V
S
L
NA
S
ANQY
SA
G
I
Y
-
W
RG
S
GW
P
--
-
-
-
G
A
E
SEEGY
I
AAFY
L
QTD
K
TN
I
NV
-
MYH
AN
T
--
-T
S
Q
R
LG
S
Y
G
P
FD
H
D
WHTL
T
FRF
P
G
GG
SL
N
VTPV
L
D
NAA
G
K
PFTL
T
R
W
T
N
AA
F
E
A
N
A
L
A
I
TDIT
GN
A
A
TYPVLI
E
S
L
T
V
G
VN
A
VA
A
fig|585397.9.peg.1123
Escherichia coli ED1a (462-657/657)
K
N
T
L
VSD
SG
S
-
G
K
KA
LR
L
E
K
P
E
NGLA
Q
KK
T
W
K
V
S
H
A
IDA
G
KG
K
E
L
FDN
GG
E
I
T
L
RFK
I
P
D
D
V
S
L
NA
S
ANQY
SA
G
I
Y
-
W
RG
S
GW
P
--
-
-
-
G
A
E
SEEGY
I
AAFY
L
QTD
K
TN
I
NV
-
MYH
AN
T
--
-T
S
Q
R
LG
S
Y
G
P
FD
H
D
WHTL
T
FRF
P
G
GG
SL
N
VTPV
L
D
NAA
G
K
PFTL
T
R
W
T
N
AA
F
E
A
N
A
L
A
I
TDIT
GN
A
A
TYPVLI
E
S
L
T
V
G
VN
A
VA
A
fig|585397.7.peg.2546
Escherichia coli ED1a (469-660/660)
G
K
G
T
V
TD
D
SG
R
-
--
KA
LR
L
E
K
Q
P
G
---
K
LT
SW
K
M
F
RT
V
A
V
E
E
A
K
N
LL
S
KGG
E
I
A
V
RFK
I
P
E
G
VEL
--
V
N
G
Q
F
V
F
GL
Y
-
WPVS
Q
WA
--
-
-
-
S
G
ATA
N
SM
LA
S
F
F
L
QTDA
S
N
LN
L
-
MYH
KG
E
--
-S
N
A
Q
LGTFGAFD
HN
WHT
V
V
FRFAGNNS
E
K
V
V
PVID
DA
E
Q
S
A
F
D
L
V
M
W
T
N
DG
F
T
AD
T
L
T
L
TDIT
GA
K
A
TYPVL
L
D
T
V
T
V
K
VN
E
S
RA
SS
fig|585397.9.peg.2543
Escherichia coli ED1a (469-660/660)
G
K
G
T
V
TD
D
SG
R
-
--
KA
LR
L
E
K
Q
P
G
---
K
LT
SW
K
M
F
RT
V
A
V
E
E
A
K
N
LL
S
KGG
E
I
A
V
RFK
I
P
E
G
VEL
--
V
N
G
Q
F
V
F
GL
Y
-
WPVS
Q
WA
--
-
-
-
S
G
ATA
N
SM
LA
S
F
F
L
QTDA
S
N
LN
L
-
MYH
KG
E
--
-S
N
A
Q
LGTFGAFD
HN
WHT
V
V
FRFAGNNS
E
K
V
V
PVID
DA
E
Q
S
A
F
D
L
V
M
W
T
N
DG
F
T
AD
T
L
T
L
TDIT
GA
K
A
TYPVL
L
D
T
V
T
V
K
VN
E
S
RA
SS
fig|585397.7.peg.1031
Escherichia coli ED1a (469-660/660)
G
K
G
T
V
TD
D
SG
R
-
--
KA
LR
L
E
K
Q
P
G
---
K
LT
SW
K
M
F
RT
V
A
V
E
E
A
K
N
LL
S
KGG
E
I
A
V
RFK
I
P
E
G
VEL
--
V
N
G
Q
F
V
F
GL
Y
-
WPVS
Q
WA
--
-
-
-
S
G
ATA
N
SM
LA
S
F
F
L
QTDA
S
N
LN
L
-
MYH
KG
E
--
-S
N
A
Q
LGTFGAFD
HN
WHT
V
V
FRFAGNNS
E
K
V
V
PVID
DA
E
Q
S
A
F
D
L
V
M
W
T
N
DG
F
T
AD
T
L
T
L
TDIT
GA
K
A
TYP
I
L
L
D
T
V
T
V
K
VN
E
S
RA
SS
fig|585397.9.peg.1030
Escherichia coli ED1a (469-660/660)
G
K
G
T
V
TD
D
SG
R
-
--
KA
LR
L
E
K
Q
P
G
---
K
LT
SW
K
M
F
RT
V
A
V
E
E
A
K
N
LL
S
KGG
E
I
A
V
RFK
I
P
E
G
VEL
--
V
N
G
Q
F
V
F
GL
Y
-
WPVS
Q
WA
--
-
-
-
S
G
ATA
N
SM
LA
S
F
F
L
QTDA
S
N
LN
L
-
MYH
KG
E
--
-S
N
A
Q
LGTFGAFD
HN
WHT
V
V
FRFAGNNS
E
K
V
V
PVID
DA
E
Q
S
A
F
D
L
V
M
W
T
N
DG
F
T
AD
T
L
T
L
TDIT
GA
K
A
TYP
I
L
L
D
T
V
T
V
K
VN
E
S
RA
SS
fig|585397.7.peg.1742
Escherichia coli ED1a (471-662/662)
G
K
G
T
V
TD
D
G
G
R
-
--
KA
LR
L
E
K
Q
P
G
---
K
LT
SW
K
M
F
RT
V
A
V
E
E
A
K
N
LL
S
KGG
E
I
A
V
RFK
I
P
D
G
S
EL
--
V
N
G
Q
F
V
F
GL
Y
-
WPVS
Q
WA
--
-
-
-
S
G
A
A
A
N
SM
LA
S
F
F
L
QTDA
S
N
LN
L
-
M
H
H
KG
T
--
-S
N
A
Q
LGTFGAFD
HN
WHT
V
V
FRFAGNNS
E
R
V
V
PVIDG
T
E
Q
T
A
F
D
L
V
M
W
T
N
DG
F
T
AD
T
L
T
L
TDIT
GA
K
A
TYPVL
L
D
T
V
T
V
K
VN
E
S
RA
SS
fig|585397.9.peg.1737
Escherichia coli ED1a (471-662/662)
G
K
G
T
V
TD
D
G
G
R
-
--
KA
LR
L
E
K
Q
P
G
---
K
LT
SW
K
M
F
RT
V
A
V
E
E
A
K
N
LL
S
KGG
E
I
A
V
RFK
I
P
D
G
S
EL
--
V
N
G
Q
F
V
F
GL
Y
-
WPVS
Q
WA
--
-
-
-
S
G
A
A
A
N
SM
LA
S
F
F
L
QTDA
S
N
LN
L
-
M
H
H
KG
T
--
-S
N
A
Q
LGTFGAFD
HN
WHT
V
V
FRFAGNNS
E
R
V
V
PVIDG
T
E
Q
T
A
F
D
L
V
M
W
T
N
DG
F
T
AD
T
L
T
L
TDIT
GA
K
A
TYPVL
L
D
T
V
T
V
K
VN
E
S
RA
SS
fig|585397.7.peg.894
Escherichia coli ED1a (437-634/634)
G
K
A
S
VV
N
D
S
A
A
E
S
GKA
M
R
V
E
K
V
Q
G
---
Q
Q
T
A
W
K
I
A
HDV
PA
S
K
A
A
E
LLQKGG
E
I
A
F
RFK
I
P
E
G
V
Q
L
--
A
E
N
R
FA
MA
L
H
-
WPVS
Q
LP
E
N
V
V
L
E
G
S
A
GN
D
M
LAAF
F
IQ
S
D
S
A
N
LN
L
-
M
Q
H
K
-
Q
--
-Q
N
A
KLGTFGAF
N
HN
WH
N
V
V
FRFAGNNS
I
S
VTPVI
N
GQ
TQ
AA
F
N
L
A
K
C
P
A
AG
L
D
N
DKL
L
I
TDIT
SN
QD
TYPVLI
E
Y
V
T
V
DI
N
N
SN
A
A
fig|585397.9.peg.894
Escherichia coli ED1a (437-634/634)
G
K
A
S
VV
N
D
S
A
A
E
S
GKA
M
R
V
E
K
V
Q
G
---
Q
Q
T
A
W
K
I
A
HDV
PA
S
K
A
A
E
LLQKGG
E
I
A
F
RFK
I
P
E
G
V
Q
L
--
A
E
N
R
FA
MA
L
H
-
WPVS
Q
LP
E
N
V
V
L
E
G
S
A
GN
D
M
LAAF
F
IQ
S
D
S
A
N
LN
L
-
M
Q
H
K
-
Q
--
-Q
N
A
KLGTFGAF
N
HN
WH
N
V
V
FRFAGNNS
I
S
VTPVI
N
GQ
TQ
AA
F
N
L
A
K
C
P
A
AG
L
D
N
DKL
L
I
TDIT
SN
QD
TYPVLI
E
Y
V
T
V
DI
N
N
SN
A
A
fig|478006.5.peg.4011
Escherichia coli O157:H7 str. EC4501 (452-648/648)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RN
A
-
TYPVLIDSI
A
VEVN
N
A
D
A
AA
fig|502346.5.peg.5585
Escherichia coli O157:H7 str. TW14588 (452-648/648)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RN
A
-
TYPVLIDSI
A
VEVN
N
A
D
A
AA
fig|562.372.peg.772
Escherichia coli 1212A (452-648/648)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RS
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|562.374.peg.5998
Escherichia coli 536A (452-648/648)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RS
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|1040638.4.peg.327
Escherichia coli O104:H4 str. LB226692 (279-475/475)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWH
M
LAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RN
A
-
TYPVLIDSI
A
VEVN
N
A
D
A
AA
fig|6666666.5357.peg.2754
Escherichia coli TY-2482 (52-248/248)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWH
M
LAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RN
A
-
TYPVLIDSI
A
VEVN
N
A
D
A
AA
fig|562.371.peg.585
Escherichia coli 1044A (419-611/614)
G
K
A
E
I
I
SDA
G
G
T
GGKA
M
KLTKE
T
G
---
K
-
SSW
Y
L
D
HD
-
AG
T
GA
E
-
LL
K
N
GG
L
I
S
CRFKV
P
G
D
L
----
V
ANQYVM
GL
Y
-
WPVSSLPQGV
T
L
T
GD
A
GNNLLA
S
FYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
Q
KLGTFGAFDNEWHTLAFRFAGNNSLQV
I
PVIDGQDG
AA
FTL
T
QSPV
GT
F
P
V
DKL
R
VTDIT
KN
A
-
TYPVLIDSI
V
VEV
K
K
A
fig|562.374.peg.290
Escherichia coli 536A (419-611/614)
G
K
A
E
I
I
SDA
G
G
T
GGKA
M
KLTKE
T
G
---
K
-
SSW
Y
L
D
HD
-
AG
T
GA
E
-
LL
K
N
GG
L
I
S
CRFKV
P
G
D
L
----
V
ANQYVM
GL
Y
-
WPVSSLPQGV
T
L
T
GD
A
GNNLLA
S
FYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
Q
KLGTFGAFDNEWHTLAFRFAGNNSLQV
I
PVIDGQDG
AA
FTL
T
QSPV
GT
F
P
V
DKL
R
VTDIT
KN
A
-
TYPVLIDSI
V
VEV
K
K
A
fig|83334.1.peg.4969
Escherichia coli O157:H7 (484-676/679)
G
K
A
E
I
I
SDA
G
G
T
GGKA
M
KLTKE
T
G
---
K
-
SSW
Y
L
D
HD
-
AG
T
GA
E
-
LL
K
N
GG
L
I
S
CRFKV
P
G
D
L
----
V
ANQYVM
GL
Y
-
WPVSSLPQGV
T
L
T
GD
A
GNNLLA
S
FYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
Q
KLGTFGAFDNEWHTLAFRFAGNNSLQV
I
PVIDGQDG
AA
FTL
T
QSPV
GT
F
P
V
DKL
R
VTDIT
KN
A
-
TYPVLIDSI
V
VEV
K
K
A
fig|478006.5.peg.1999
Escherichia coli O157:H7 str. EC4501 (419-611/614)
G
K
A
E
I
I
SDA
G
G
T
GGKA
M
KLTKE
T
G
---
K
-
SSW
Y
L
D
HD
-
AG
T
GA
E
-
LL
K
N
GG
L
I
S
CRFKV
P
G
D
L
----
V
ANQYVM
GL
Y
-
WPVSSLPQGV
T
L
T
GD
A
GNNLLA
S
FYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
Q
KLGTFGAFDNEWHTLAFRFAGNNSLQV
I
PVIDGQDG
AA
FTL
T
QSPV
GT
F
P
V
DKL
R
VTDIT
KN
A
-
TYPVLIDSI
V
VEV
K
K
A
fig|637388.3.peg.3677
Escherichia coli O157:H7 str. FRIK2000 (419-611/614)
G
K
A
E
I
I
SDA
G
G
T
GGKA
M
KLTKE
T
G
---
K
-
SSW
Y
L
D
HD
-
AG
T
GA
E
-
LL
K
N
GG
L
I
S
CRFKV
P
G
D
L
----
V
ANQYVM
GL
Y
-
WPVSSLPQGV
T
L
T
GD
A
GNNLLA
S
FYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
Q
KLGTFGAFDNEWHTLAFRFAGNNSLQV
I
PVIDGQDG
AA
FTL
T
QSPV
GT
F
P
V
DKL
R
VTDIT
KN
A
-
TYPVLIDSI
V
VEV
K
K
A
fig|570506.3.peg.4576
Escherichia coli O157:H7 str. FRIK966 (419-611/614)
G
K
A
E
I
I
SDA
G
G
T
GGKA
M
KLTKE
T
G
---
K
-
SSW
Y
L
D
HD
-
AG
T
GA
E
-
LL
K
N
GG
L
I
S
CRFKV
P
G
D
L
----
V
ANQYVM
GL
Y
-
WPVSSLPQGV
T
L
T
GD
A
GNNLLA
S
FYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
Q
KLGTFGAFDNEWHTLAFRFAGNNSLQV
I
PVIDGQDG
AA
FTL
T
QSPV
GT
F
P
V
DKL
R
VTDIT
KN
A
-
TYPVLIDSI
V
VEV
K
K
A
fig|386585.9.peg.5215
Escherichia coli O157:H7 str. Sakai (419-611/614)
G
K
A
E
I
I
SDA
G
G
T
GGKA
M
KLTKE
T
G
---
K
-
SSW
Y
L
D
HD
-
AG
T
GA
E
-
LL
K
N
GG
L
I
S
CRFKV
P
G
D
L
----
V
ANQYVM
GL
Y
-
WPVSSLPQGV
T
L
T
GD
A
GNNLLA
S
FYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
Q
KLGTFGAFDNEWHTLAFRFAGNNSLQV
I
PVIDGQDG
AA
FTL
T
QSPV
GT
F
P
V
DKL
R
VTDIT
KN
A
-
TYPVLIDSI
V
VEV
K
K
A
fig|502346.5.peg.851
Escherichia coli O157:H7 str. TW14588 (419-611/614)
G
K
A
E
I
I
SDA
G
G
T
GGKA
M
KLTKE
T
G
---
K
-
SSW
Y
L
D
HD
-
AG
T
GA
E
-
LL
K
N
GG
L
I
S
CRFKV
P
G
D
L
----
V
ANQYVM
GL
Y
-
WPVSSLPQGV
T
L
T
GD
A
GNNLLA
S
FYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
Q
KLGTFGAFDNEWHTLAFRFAGNNSLQV
I
PVIDGQDG
AA
FTL
T
QSPV
GT
F
P
V
DKL
R
VTDIT
KN
A
-
TYPVLIDSI
V
VEV
K
K
A
fig|562.371.peg.4122
Escherichia coli 1044A (454-643/645)
GRA
L
VV
D
DA
GA
A
GGKA
LRW
TK
Q
T
G
---
S
-
SSW
F
M
Q
HD
-
AG
N
GA
D
-
LL
E
KGG
L
I
S
CRFKV
D
G
T
L
----
T
ANQY
AL
A
L
Y
-
WPVSSLPQGV
T
L
E
G
N
A
G
H
NLLA
S
FY
V
Q
S
DA
T
DLNV
-
MYH
KG
N
-
A
GQ
N
T
KLG
S
FGAFDNEWHTL
G
FRFAGNNS
I
E
VTPVIDG
K
DGTPF
M
L
S
QSPV
GT
F
T
ADKL
R
VTDIT
SG
A
-
TYPVLI
E
SI
T
VEVN
fig|562.373.peg.4897
Escherichia coli 1125A (454-643/645)
GRA
L
VV
D
DA
GA
A
GGKA
LRW
TK
Q
T
G
---
S
-
SSW
F
M
Q
HD
-
AG
N
GA
D
-
LL
E
KGG
L
I
S
CRFKV
D
G
T
L
----
T
ANQY
AL
A
L
Y
-
WPVSSLPQGV
T
L
E
G
N
A
G
H
NLLA
S
FY
V
Q
S
DA
T
DLNV
-
MYH
KG
N
-
A
GQ
N
T
KLG
S
FGAFDNEWHTL
G
FRFAGNNS
I
E
VTPVIDG
K
DGTPF
M
L
S
QSPV
GT
F
T
ADKL
R
VTDIT
SG
A
-
TYPVLI
E
SI
T
VEVN
fig|562.372.peg.613
Escherichia coli 1212A (454-643/645)
GRA
L
VV
D
DA
GA
A
GGKA
LRW
TK
Q
T
G
---
S
-
SSW
F
M
Q
HD
-
AG
N
GA
D
-
LL
E
KGG
L
I
S
CRFKV
D
G
T
L
----
T
ANQY
AL
A
L
Y
-
WPVSSLPQGV
T
L
E
G
N
A
G
H
NLLA
S
FY
V
Q
S
DA
T
DLNV
-
MYH
KG
N
-
A
GQ
N
T
KLG
S
FGAFDNEWHTL
G
FRFAGNNS
I
E
VTPVIDG
K
DGTPF
M
L
S
QSPV
GT
F
T
ADKL
R
VTDIT
SG
A
-
TYPVLI
E
SI
T
VEVN
fig|562.374.peg.1554
Escherichia coli 536A (454-643/645)
GRA
L
VV
D
DA
GA
A
GGKA
LRW
TK
Q
T
G
---
S
-
SSW
F
M
Q
HD
-
AG
N
GA
D
-
LL
E
KGG
L
I
S
CRFKV
D
G
T
L
----
T
ANQY
AL
A
L
Y
-
WPVSSLPQGV
T
L
E
G
N
A
G
H
NLLA
S
FY
V
Q
S
DA
T
DLNV
-
MYH
KG
N
-
A
GQ
N
T
KLG
S
FGAFDNEWHTL
G
FRFAGNNS
I
E
VTPVIDG
K
DGTPF
M
L
S
QSPV
GT
F
T
ADKL
R
VTDIT
SG
A
-
TYPVLI
E
SI
T
VEVN
fig|340185.3.peg.4983
Escherichia coli E22 (454-643/645)
GRA
L
VV
D
DA
GA
A
GGKA
LRW
TK
Q
T
G
---
S
-
SSW
F
M
Q
HD
-
AG
N
GA
D
-
LL
E
KGG
L
I
S
CRFKV
D
G
T
L
----
T
ANQY
AL
A
L
Y
-
WPVSSLPQGV
T
L
E
G
N
A
G
H
NLLA
S
FY
V
Q
S
DA
T
DLNV
-
MYH
KG
N
-
A
GQ
N
T
KLG
S
FGAFDNEWHTL
G
FRFAGNNS
I
E
VTPVIDG
K
DGTPF
M
L
S
QSPV
GT
F
T
ADKL
R
VTDIT
SG
A
-
TYPVLI
E
SI
T
VEVN
fig|340185.4.peg.5271
Escherichia coli E22 (454-643/645)
GRA
L
VV
D
DA
GA
A
GGKA
LRW
TK
Q
T
G
---
S
-
SSW
F
M
Q
HD
-
AG
N
GA
D
-
LL
E
KGG
L
I
S
CRFKV
D
G
T
L
----
T
ANQY
AL
A
L
Y
-
WPVSSLPQGV
T
L
E
G
N
A
G
H
NLLA
S
FY
V
Q
S
DA
T
DLNV
-
MYH
KG
N
-
A
GQ
N
T
KLG
S
FGAFDNEWHTL
G
FRFAGNNS
I
E
VTPVIDG
K
DGTPF
M
L
S
QSPV
GT
F
T
ADKL
R
VTDIT
SG
A
-
TYPVLI
E
SI
T
VEVN
fig|585395.4.peg.1775
Escherichia coli O103:H2 str. 12009 (454-643/645)
GRA
L
VV
D
DA
GA
A
GGKA
LRW
TK
Q
T
G
---
S
-
SSW
F
M
Q
HD
-
AG
N
GA
D
-
LL
E
KGG
L
I
S
CRFKV
D
G
T
L
----
T
ANQY
AL
A
L
Y
-
WPVSSLPQGV
T
L
E
G
N
A
G
H
NLLA
S
FY
V
Q
S
DA
T
DLNV
-
MYH
KG
N
-
A
GQ
N
T
KLG
S
FGAFDNEWHTL
G
FRFAGNNS
I
E
VTPVIDG
K
DGTPF
M
L
S
QSPV
GT
F
T
ADKL
R
VTDIT
SG
A
-
TYPVLI
E
SI
T
VEVN
fig|83334.1.peg.1574
Escherichia coli O157:H7 (454-643/645)
GRA
L
VV
D
DA
GA
A
GGKA
LRW
TK
Q
T
G
---
S
-
SSW
F
M
Q
HD
-
AG
N
GA
D
-
LL
E
KGG
L
I
S
CRFKV
D
G
T
L
----
T
ANQY
AL
A
L
Y
-
WPVSSLPQGV
T
L
E
G
N
A
G
H
NLLA
S
FY
V
Q
S
DA
T
DLNV
-
MYH
KG
N
-
A
GQ
N
T
KLG
S
FGAFDNEWHTL
G
FRFAGNNS
I
E
VTPVIDG
K
DGTPF
M
L
S
QSPV
GT
F
T
ADKL
R
VTDIT
SG
A
-
TYPVLI
E
SI
T
VEVN
fig|444454.5.peg.6014
Escherichia coli O157:H7 str. EC4024 (239-428/430)
GRA
L
VV
D
DA
GA
A
GGKA
LRW
TK
Q
T
G
---
S
-
SSW
F
M
Q
HD
-
AG
N
GA
D
-
LL
E
KGG
L
I
S
CRFKV
D
G
T
L
----
T
ANQY
AL
A
L
Y
-
WPVSSLPQGV
T
L
E
G
N
A
G
H
NLLA
S
FY
V
Q
S
DA
T
DLNV
-
MYH
KG
N
-
A
GQ
N
T
KLG
S
FGAFDNEWHTL
G
FRFAGNNS
I
E
VTPVIDG
K
DGTPF
M
L
S
QSPV
GT
F
T
ADKL
R
VTDIT
SG
A
-
TYPVLI
E
SI
T
VEVN
fig|444449.5.peg.4872
Escherichia coli O157:H7 str. EC4042 (239-428/430)
GRA
L
VV
D
DA
GA
A
GGKA
LRW
TK
Q
T
G
---
S
-
SSW
F
M
Q
HD
-
AG
N
GA
D
-
LL
E
KGG
L
I
S
CRFKV
D
G
T
L
----
T
ANQY
AL
A
L
Y
-
WPVSSLPQGV
T
L
E
G
N
A
G
H
NLLA
S
FY
V
Q
S
DA
T
DLNV
-
MYH
KG
N
-
A
GQ
N
T
KLG
S
FGAFDNEWHTL
G
FRFAGNNS
I
E
VTPVIDG
K
DGTPF
M
L
S
QSPV
GT
F
T
ADKL
R
VTDIT
SG
A
-
TYPVLI
E
SI
T
VEVN
fig|444448.5.peg.4135
Escherichia coli O157:H7 str. EC4045 (239-428/430)
GRA
L
VV
D
DA
GA
A
GGKA
LRW
TK
Q
T
G
---
S
-
SSW
F
M
Q
HD
-
AG
N
GA
D
-
LL
E
KGG
L
I
S
CRFKV
D
G
T
L
----
T
ANQY
AL
A
L
Y
-
WPVSSLPQGV
T
L
E
G
N
A
G
H
NLLA
S
FY
V
Q
S
DA
T
DLNV
-
MYH
KG
N
-
A
GQ
N
T
KLG
S
FGAFDNEWHTL
G
FRFAGNNS
I
E
VTPVIDG
K
DGTPF
M
L
S
QSPV
GT
F
T
ADKL
R
VTDIT
SG
A
-
TYPVLI
E
SI
T
VEVN
fig|444453.5.peg.4795
Escherichia coli O157:H7 str. EC4076 (239-428/430)
GRA
L
VV
D
DA
GA
A
GGKA
LRW
TK
Q
T
G
---
S
-
SSW
F
M
Q
HD
-
AG
N
GA
D
-
LL
E
KGG
L
I
S
CRFKV
D
G
T
L
----
T
ANQY
AL
A
L
Y
-
WPVSSLPQGV
T
L
E
G
N
A
G
H
NLLA
S
FY
V
Q
S
DA
T
DLNV
-
MYH
KG
N
-
A
GQ
N
T
KLG
S
FGAFDNEWHTL
G
FRFAGNNS
I
E
VTPVIDG
K
DGTPF
M
L
S
QSPV
GT
F
T
ADKL
R
VTDIT
SG
A
-
TYPVLI
E
SI
T
VEVN
fig|444452.5.peg.4210
Escherichia coli O157:H7 str. EC4113 (239-428/430)
GRA
L
VV
D
DA
GA
A
GGKA
LRW
TK
Q
T
G
---
S
-
SSW
F
M
Q
HD
-
AG
N
GA
D
-
LL
E
KGG
L
I
S
CRFKV
D
G
T
L
----
T
ANQY
AL
A
L
Y
-
WPVSSLPQGV
T
L
E
G
N
A
G
H
NLLA
S
FY
V
Q
S
DA
T
DLNV
-
MYH
KG
N
-
A
GQ
N
T
KLG
S
FGAFDNEWHTL
G
FRFAGNNS
I
E
VTPVIDG
K
DGTPF
M
L
S
QSPV
GT
F
T
ADKL
R
VTDIT
SG
A
-
TYPVLI
E
SI
T
VEVN
fig|444450.8.peg.1596
Escherichia coli O157:H7 str. EC4115 (239-428/430)
GRA
L
VV
D
DA
GA
A
GGKA
LRW
TK
Q
T
G
---
S
-
SSW
F
M
Q
HD
-
AG
N
GA
D
-
LL
E
KGG
L
I
S
CRFKV
D
G
T
L
----
T
ANQY
AL
A
L
Y
-
WPVSSLPQGV
T
L
E
G
N
A
G
H
NLLA
S
FY
V
Q
S
DA
T
DLNV
-
MYH
KG
N
-
A
GQ
N
T
KLG
S
FGAFDNEWHTL
G
FRFAGNNS
I
E
VTPVIDG
K
DGTPF
M
L
S
QSPV
GT
F
T
ADKL
R
VTDIT
SG
A
-
TYPVLI
E
SI
T
VEVN
fig|444451.5.peg.4242
Escherichia coli O157:H7 str. EC4196 (239-428/430)
GRA
L
VV
D
DA
GA
A
GGKA
LRW
TK
Q
T
G
---
S
-
SSW
F
M
Q
HD
-
AG
N
GA
D
-
LL
E
KGG
L
I
S
CRFKV
D
G
T
L
----
T
ANQY
AL
A
L
Y
-
WPVSSLPQGV
T
L
E
G
N
A
G
H
NLLA
S
FY
V
Q
S
DA
T
DLNV
-
MYH
KG
N
-
A
GQ
N
T
KLG
S
FGAFDNEWHTL
G
FRFAGNNS
I
E
VTPVIDG
K
DGTPF
M
L
S
QSPV
GT
F
T
ADKL
R
VTDIT
SG
A
-
TYPVLI
E
SI
T
VEVN
fig|444447.5.peg.4374
Escherichia coli O157:H7 str. EC4206 (239-428/430)
GRA
L
VV
D
DA
GA
A
GGKA
LRW
TK
Q
T
G
---
S
-
SSW
F
M
Q
HD
-
AG
N
GA
D
-
LL
E
KGG
L
I
S
CRFKV
D
G
T
L
----
T
ANQY
AL
A
L
Y
-
WPVSSLPQGV
T
L
E
G
N
A
G
H
NLLA
S
FY
V
Q
S
DA
T
DLNV
-
MYH
KG
N
-
A
GQ
N
T
KLG
S
FGAFDNEWHTL
G
FRFAGNNS
I
E
VTPVIDG
K
DGTPF
M
L
S
QSPV
GT
F
T
ADKL
R
VTDIT
SG
A
-
TYPVLI
E
SI
T
VEVN
fig|478004.5.peg.4471
Escherichia coli O157:H7 str. EC4401 (239-428/430)
GRA
L
VV
D
DA
GA
A
GGKA
LRW
TK
Q
T
G
---
S
-
SSW
F
M
Q
HD
-
AG
N
GA
D
-
LL
E
KGG
L
I
S
CRFKV
D
G
T
L
----
T
ANQY
AL
A
L
Y
-
WPVSSLPQGV
T
L
E
G
N
A
G
H
NLLA
S
FY
V
Q
S
DA
T
DLNV
-
MYH
KG
N
-
A
GQ
N
T
KLG
S
FGAFDNEWHTL
G
FRFAGNNS
I
E
VTPVIDG
K
DGTPF
M
L
S
QSPV
GT
F
T
ADKL
R
VTDIT
SG
A
-
TYPVLI
E
SI
T
VEVN
fig|478005.5.peg.5014
Escherichia coli O157:H7 str. EC4486 (209-398/400)
GRA
L
VV
D
DA
GA
A
GGKA
LRW
TK
Q
T
G
---
S
-
SSW
F
M
Q
HD
-
AG
N
GA
D
-
LL
E
KGG
L
I
S
CRFKV
D
G
T
L
----
T
ANQY
AL
A
L
Y
-
WPVSSLPQGV
T
L
E
G
N
A
G
H
NLLA
S
FY
V
Q
S
DA
T
DLNV
-
MYH
KG
N
-
A
GQ
N
T
KLG
S
FGAFDNEWHTL
G
FRFAGNNS
I
E
VTPVIDG
K
DGTPF
M
L
S
QSPV
GT
F
T
ADKL
R
VTDIT
SG
A
-
TYPVLI
E
SI
T
VEVN
fig|478006.5.peg.4907
Escherichia coli O157:H7 str. EC4501 (454-643/645)
GRA
L
VV
D
DA
GA
A
GGKA
LRW
TK
Q
T
G
---
S
-
SSW
F
M
Q
HD
-
AG
N
GA
D
-
LL
E
KGG
L
I
S
CRFKV
D
G
T
L
----
T
ANQY
AL
A
L
Y
-
WPVSSLPQGV
T
L
E
G
N
A
G
H
NLLA
S
FY
V
Q
S
DA
T
DLNV
-
MYH
KG
N
-
A
GQ
N
T
KLG
S
FGAFDNEWHTL
G
FRFAGNNS
I
E
VTPVIDG
K
DGTPF
M
L
S
QSPV
GT
F
T
ADKL
R
VTDIT
SG
A
-
TYPVLI
E
SI
T
VEVN
fig|478008.5.peg.5159
Escherichia coli O157:H7 str. EC869 (454-643/645)
GRA
L
VV
D
DA
GA
A
GGKA
LRW
TK
Q
T
G
---
S
-
SSW
F
M
Q
HD
-
AG
N
GA
D
-
LL
E
KGG
L
I
S
CRFKV
D
G
T
L
----
T
ANQY
AL
A
L
Y
-
WPVSSLPQGV
T
L
E
G
N
A
G
H
NLLA
S
FY
V
Q
S
DA
T
DLNV
-
MYH
KG
N
-
A
GQ
N
T
KLG
S
FGAFDNEWHTL
G
FRFAGNNS
I
E
VTPVIDG
K
DGTPF
M
L
S
QSPV
GT
F
T
ADKL
R
VTDIT
SG
A
-
TYPVLI
E
SI
T
VEVN
fig|637388.3.peg.4268
Escherichia coli O157:H7 str. FRIK2000 (402-591/593)
GRA
L
VV
D
DA
GA
A
GGKA
LRW
TK
Q
T
G
---
S
-
SSW
F
M
Q
HD
-
AG
N
GA
D
-
LL
E
KGG
L
I
S
CRFKV
D
G
T
L
----
T
ANQY
AL
A
L
Y
-
WPVSSLPQGV
T
L
E
G
N
A
G
H
NLLA
S
FY
V
Q
S
DA
T
DLNV
-
MYH
KG
N
-
A
GQ
N
T
KLG
S
FGAFDNEWHTL
G
FRFAGNNS
I
E
VTPVIDG
K
DGTPF
M
L
S
QSPV
GT
F
T
ADKL
R
VTDIT
SG
A
-
TYPVLI
E
SI
T
VEVN
fig|570506.3.peg.1951
Escherichia coli O157:H7 str. FRIK966 (411-600/602)
GRA
L
VV
D
DA
GA
A
GGKA
LRW
TK
Q
T
G
---
S
-
SSW
F
M
Q
HD
-
AG
N
GA
D
-
LL
E
KGG
L
I
S
CRFKV
D
G
T
L
----
T
ANQY
AL
A
L
Y
-
WPVSSLPQGV
T
L
E
G
N
A
G
H
NLLA
S
FY
V
Q
S
DA
T
DLNV
-
MYH
KG
N
-
A
GQ
N
T
KLG
S
FGAFDNEWHTL
G
FRFAGNNS
I
E
VTPVIDG
K
DGTPF
M
L
S
QSPV
GT
F
T
ADKL
R
VTDIT
SG
A
-
TYPVLI
E
SI
T
VEVN
fig|386585.9.peg.1629
Escherichia coli O157:H7 str. Sakai (454-643/645)
GRA
L
VV
D
DA
GA
A
GGKA
LRW
TK
Q
T
G
---
S
-
SSW
F
M
Q
HD
-
AG
N
GA
D
-
LL
E
KGG
L
I
S
CRFKV
D
G
T
L
----
T
ANQY
AL
A
L
Y
-
WPVSSLPQGV
T
L
E
G
N
A
G
H
NLLA
S
FY
V
Q
S
DA
T
DLNV
-
MYH
KG
N
-
A
GQ
N
T
KLG
S
FGAFDNEWHTL
G
FRFAGNNS
I
E
VTPVIDG
K
DGTPF
M
L
S
QSPV
GT
F
T
ADKL
R
VTDIT
SG
A
-
TYPVLI
E
SI
T
VEVN
fig|544404.4.peg.1459
Escherichia coli O157:H7 str. TW14359 (239-428/430)
GRA
L
VV
D
DA
GA
A
GGKA
LRW
TK
Q
T
G
---
S
-
SSW
F
M
Q
HD
-
AG
N
GA
D
-
LL
E
KGG
L
I
S
CRFKV
D
G
T
L
----
T
ANQY
AL
A
L
Y
-
WPVSSLPQGV
T
L
E
G
N
A
G
H
NLLA
S
FY
V
Q
S
DA
T
DLNV
-
MYH
KG
N
-
A
GQ
N
T
KLG
S
FGAFDNEWHTL
G
FRFAGNNS
I
E
VTPVIDG
K
DGTPF
M
L
S
QSPV
GT
F
T
ADKL
R
VTDIT
SG
A
-
TYPVLI
E
SI
T
VEVN
fig|502346.5.peg.2757
Escherichia coli O157:H7 str. TW14588 (454-643/645)
GRA
L
VV
D
DA
GA
A
GGKA
LRW
TK
Q
T
G
---
S
-
SSW
F
M
Q
HD
-
AG
N
GA
D
-
LL
E
KGG
L
I
S
CRFKV
D
G
T
L
----
T
ANQY
AL
A
L
Y
-
WPVSSLPQGV
T
L
E
G
N
A
G
H
NLLA
S
FY
V
Q
S
DA
T
DLNV
-
MYH
KG
N
-
A
GQ
N
T
KLG
S
FGAFDNEWHTL
G
FRFAGNNS
I
E
VTPVIDG
K
DGTPF
M
L
S
QSPV
GT
F
T
ADKL
R
VTDIT
SG
A
-
TYPVLI
E
SI
T
VEVN
fig|701177.3.peg.1945
Escherichia coli O55:H7 str. CB9615 (454-643/645)
GRA
L
VV
D
DA
GA
A
GGKA
LRW
TK
Q
T
G
---
S
-
SSW
F
M
Q
HD
-
AG
N
GA
D
-
LL
E
KGG
L
I
S
CRFKV
D
G
T
L
----
T
ANQY
AL
A
L
Y
-
WPVSSLPQGV
T
L
E
G
N
A
G
H
NLLA
S
FY
V
Q
S
DA
T
DLNV
-
MYH
KG
N
-
A
GQ
N
T
KLG
S
FGAFDNEWHTL
G
FRFAGNNS
I
E
VTPVIDG
K
DGTPF
M
L
S
QSPV
GT
F
T
ADKL
R
VTDIT
SG
A
-
TYPVLI
E
SI
T
VEVN
fig|562.372.peg.5690
Escherichia coli 1212A (452-648/648)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RN
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|562.372.peg.5888
Escherichia coli 1212A (449-645/645)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RN
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|562.374.peg.541
Escherichia coli 536A (452-648/648)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RN
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|585395.4.peg.2432
Escherichia coli O103:H2 str. 12009 (449-645/645)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RN
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|585395.4.peg.2979
Escherichia coli O103:H2 str. 12009 (352-548/548)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RN
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|585396.4.peg.2520
Escherichia coli O111:H- str. 11128 (449-645/645)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RN
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|585396.4.peg.2691
Escherichia coli O111:H- str. 11128 (449-645/645)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RN
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|478006.5.peg.4508
Escherichia coli O157:H7 str. EC4501 (452-648/648)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RN
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|478007.5.peg.5766
Escherichia coli O157:H7 str. EC508 (39-235/235)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RN
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|478008.5.peg.5432
Escherichia coli O157:H7 str. EC869 (449-645/645)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RN
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|637388.3.peg.4354
Escherichia coli O157:H7 str. FRIK2000 (449-645/645)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RN
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|585396.4.peg.1661
Escherichia coli O111:H- str. 11128 (452-648/648)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
KG
A
-
TYPVLIDSI
A
VEVN
N
TDTAA
fig|340185.3.peg.4820
Escherichia coli E22 (452-648/648)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
X
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|340185.4.peg.5091
Escherichia coli E22 (452-648/648)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
X
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|585396.4.peg.1196
Escherichia coli O111:H- str. 11128 (352-548/548)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|155864.1.peg.1286
Escherichia coli O157:H7 EDL933 (449-645/645)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|155864.8.peg.5404
Escherichia coli O157:H7 EDL933 (352-548/548)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|444454.5.peg.186
Escherichia coli O157:H7 str. EC4024 (452-648/648)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|444454.5.peg.2204
Escherichia coli O157:H7 str. EC4024 (370-566/566)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|444449.5.peg.85
Escherichia coli O157:H7 str. EC4042 (452-648/648)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|444449.5.peg.1670
Escherichia coli O157:H7 str. EC4042 (352-548/548)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|444448.5.peg.426
Escherichia coli O157:H7 str. EC4045 (352-548/548)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|444448.5.peg.4442
Escherichia coli O157:H7 str. EC4045 (452-648/648)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|444453.5.peg.1773
Escherichia coli O157:H7 str. EC4076 (370-566/566)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|444453.5.peg.4981
Escherichia coli O157:H7 str. EC4076 (452-648/648)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|444452.5.peg.1340
Escherichia coli O157:H7 str. EC4113 (370-566/566)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|444452.5.peg.4014
Escherichia coli O157:H7 str. EC4113 (452-648/648)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|444450.8.peg.1904
Escherichia coli O157:H7 str. EC4115 (452-648/648)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|444450.8.peg.3208
Escherichia coli O157:H7 str. EC4115 (452-648/648)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|444450.8.peg.3516
Escherichia coli O157:H7 str. EC4115 (370-566/566)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|444451.5.peg.609
Escherichia coli O157:H7 str. EC4196 (370-566/566)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|444451.5.peg.2650
Escherichia coli O157:H7 str. EC4196 (452-648/648)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|444447.5.peg.561
Escherichia coli O157:H7 str. EC4206 (352-548/548)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|478005.5.peg.2046
Escherichia coli O157:H7 str. EC4486 (449-645/645)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|544404.4.peg.1765
Escherichia coli O157:H7 str. TW14359 (452-648/648)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|544404.4.peg.3319
Escherichia coli O157:H7 str. TW14359 (352-548/548)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|701177.3.peg.1710
Escherichia coli O55:H7 str. CB9615 (452-648/648)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|562.371.peg.4932
Escherichia coli 1044A (452-648/648)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
V
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
KG
A
-
TYPVLIDSI
A
VEVN
N
TDTAA
fig|562.371.peg.4933
Escherichia coli 1044A (452-648/648)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
V
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
KG
A
-
TYPVLIDSI
A
VEVN
N
TDTAA
fig|562.374.peg.106
Escherichia coli 536A (452-648/648)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
V
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
KG
A
-
TYPVLIDSI
A
VEVN
N
TDTAA
fig|83334.1.peg.2968
Escherichia coli O157:H7 (452-648/648)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
V
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
KG
A
-
TYPVLIDSI
A
VEVN
N
TDTAA
fig|155864.1.peg.2979
Escherichia coli O157:H7 EDL933 (452-648/648)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
V
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
KG
A
-
TYPVLIDSI
A
VEVN
N
TDTAA
fig|155864.8.peg.2869
Escherichia coli O157:H7 EDL933 (452-648/648)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
V
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
KG
A
-
TYPVLIDSI
A
VEVN
N
TDTAA
fig|386585.9.peg.3108
Escherichia coli O157:H7 str. Sakai (452-648/648)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
V
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
KG
A
-
TYPVLIDSI
A
VEVN
N
TDTAA
fig|502346.5.peg.4409
Escherichia coli O157:H7 str. TW14588 (452-648/648)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
V
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
KG
A
-
TYPVLIDSI
A
VEVN
N
TDTAA
fig|573235.3.peg.1230
Escherichia coli O26:H11 str. 11368 (449-645/645)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RN
A
-
TYPVLIDSI
V
VEVN
S
TDTAA
fig|573235.3.peg.1625
Escherichia coli O26:H11 str. 11368 (449-645/645)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RN
A
-
TYPVLIDSI
V
VEVN
S
TDTAA
fig|585395.4.peg.1449
Escherichia coli O103:H2 str. 12009 (452-648/648)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLG
S
FGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RN
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|562.375.peg.2429
Escherichia coli EC4100B (449-645/645)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
I
SW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|550672.3.peg.709
Escherichia coli B088 (453-646/646)
G
S
A
I
I
V
D
DA
GA
S
GGKA
L
KLTK
Q
T
G
---
-
-
K
SW
F
M
Q
HD
-
AG
N
GA
D
-
LL
E
KGG
L
V
S
CRFK
L
D
G
A
L
----
T
ANQY
AL
A
L
Y
-
WPVSSLPQGV
T
L
E
G
N
A
G
H
NLLA
S
FY
V
Q
S
DA
T
DLNV
-
MYH
KG
N
-
P
DQ
N
T
KLG
S
FGAF
N
NEWHTLAFRFAGNNS
I
QVTPVIDG
K
DGTPF
M
L
S
QSPV
GT
L
A
ADKL
R
L
TD
L
T
ST
A
-
TYPVLIDSI
L
VEVN
N
PS
A
G
fig|444454.5.peg.1634
Escherichia coli O157:H7 str. EC4024 (449-645/645)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLG
S
FGAFDNEWH
A
LAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RN
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|444450.8.peg.2918
Escherichia coli O157:H7 str. EC4115 (449-645/645)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLG
S
FGAFDNEWH
A
LAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RN
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|562.373.peg.3496
Escherichia coli 1125A (449-645/645)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
G
V
GGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLG
S
FGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|478007.5.peg.1389
Escherichia coli O157:H7 str. EC508 (370-566/566)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
G
V
GGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLG
S
FGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|562.373.peg.3828
Escherichia coli 1125A (452-648/648)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLG
S
FGAFDNEWH
A
LAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|444454.5.peg.1896
Escherichia coli O157:H7 str. EC4024 (452-648/648)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLG
S
FGAFDNEWH
A
LAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|444449.5.peg.1124
Escherichia coli O157:H7 str. EC4042 (449-645/645)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLG
S
FGAFDNEWH
A
LAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|444449.5.peg.1355
Escherichia coli O157:H7 str. EC4042 (452-648/648)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLG
S
FGAFDNEWH
A
LAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|444448.5.peg.119
Escherichia coli O157:H7 str. EC4045 (452-648/648)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLG
S
FGAFDNEWH
A
LAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|444448.5.peg.5400
Escherichia coli O157:H7 str. EC4045 (449-645/645)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLG
S
FGAFDNEWH
A
LAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|444453.5.peg.4924
Escherichia coli O157:H7 str. EC4076 (452-648/648)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLG
S
FGAFDNEWH
A
LAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|444453.5.peg.5350
Escherichia coli O157:H7 str. EC4076 (449-645/645)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLG
S
FGAFDNEWH
A
LAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|444453.5.peg.5702
Escherichia coli O157:H7 str. EC4076 (139-335/335)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLG
S
FGAFDNEWH
A
LAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|444452.5.peg.5730
Escherichia coli O157:H7 str. EC4113 (115-311/311)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLG
S
FGAFDNEWH
A
LAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|444450.8.peg.3143
Escherichia coli O157:H7 str. EC4115 (452-648/648)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLG
S
FGAFDNEWH
A
LAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|444451.5.peg.5394
Escherichia coli O157:H7 str. EC4196 (449-645/645)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLG
S
FGAFDNEWH
A
LAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|444451.5.peg.5503
Escherichia coli O157:H7 str. EC4196 (452-648/648)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLG
S
FGAFDNEWH
A
LAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|444451.5.peg.5653
Escherichia coli O157:H7 str. EC4196 (139-335/335)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLG
S
FGAFDNEWH
A
LAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|444447.5.peg.17
Escherichia coli O157:H7 str. EC4206 (449-645/645)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLG
S
FGAFDNEWH
A
LAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|444447.5.peg.249
Escherichia coli O157:H7 str. EC4206 (452-648/648)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLG
S
FGAFDNEWH
A
LAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|444447.5.peg.5352
Escherichia coli O157:H7 str. EC4206 (452-648/648)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLG
S
FGAFDNEWH
A
LAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|478004.5.peg.1937
Escherichia coli O157:H7 str. EC4401 (370-566/566)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLG
S
FGAFDNEWH
A
LAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|478005.5.peg.5348
Escherichia coli O157:H7 str. EC4486 (452-648/648)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLG
S
FGAFDNEWH
A
LAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|544404.4.peg.2781
Escherichia coli O157:H7 str. TW14359 (449-645/645)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLG
S
FGAFDNEWH
A
LAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|544404.4.peg.3011
Escherichia coli O157:H7 str. TW14359 (452-648/648)
GRA
E
VVSDAEG
T
GGKAVKLTKE
A
G
---
K
-
SSW
V
L
E
YA
-
AG
N
GA
A
-
LLQKGG
Q
I
R
CRFKV
S
G
A
L
----
A
ANQYVMAFY
-
WPVSSLPQGV
A
L
T
GDGGNNLLAAFYIQTDAKDLNV
-
MYHNA
K
VA
TN
N
L
KLG
S
FGAFDNEWH
A
LAFRFAGNNSLQVTPVIDGQDGTPFTL
T
QSPV
SA
F
A
ADKL
H
VTDIT
RG
A
-
TYPVLIDSI
A
VEVN
S
TDTAA
fig|562.375.peg.2044
Escherichia coli EC4100B (474-653/653)
T
GGKA
L
Q
L
N
K
P
E
N
---
-
-
HI
W
F
L
E
HD
A
AG
Q
G
V
E
-
LL
K
KGG
R
V
S
V
RFK
L
P
G
S
L
----
V
P
N
R
FALG
I
Y
-
W
Q
L
SSLP
E
GV
T
L
-
A
E
E
GN
D
M
L
M
S
F
F
L
QTDA
TN
LN
A
-
MYH
K
K
P
--
--
N
A
KL
D
TFG
V
FDN
G
WHTLAF
E
FAGNNS
I
QVTPV
L
D
E
K
R
GTPFTL
V
K
SP
A
SG
-
A
ADKL
Q
L
T
G
I
S
KA
A
-
TY
T
L
LIDS
V
K
VEVN
N
A
D
A
AA
fig|585035.6.peg.553
Escherichia coli S88 (474-653/653)
T
GGKA
L
Q
L
N
K
P
E
N
---
-
-
HI
W
F
L
E
HD
A
AG
Q
GA
E
-
LL
K
KGG
R
V
S
V
RFK
L
P
G
S
L
----
V
P
NQ
FALG
I
Y
-
W
Q
L
SSLP
E
GV
T
L
-
A
E
E
GN
D
M
L
M
S
F
F
L
QTDA
TN
LN
A
-
M
H
H
K
K
P
--
--
N
A
KL
D
TFG
V
FDN
G
WHTLAF
E
FAGNNS
I
QVTPV
L
D
E
K
R
GTPFTL
V
K
SP
A
SG
-
A
ADKL
Q
L
T
G
I
S
KA
A
-
TY
T
L
LIDS
V
K
VEVN
N
A
D
A
AA
fig|525281.3.peg.1496
Escherichia coli 83972 (474-653/653)
T
GGKA
L
Q
L
N
K
P
E
N
---
-
-
HI
W
F
L
E
HD
A
AG
Q
G
V
E
-
LL
K
KGG
R
V
S
V
RFK
L
P
G
S
L
----
V
P
NQ
FALG
I
Y
-
W
Q
L
SSLP
E
GV
T
L
-
A
E
E
GN
D
M
L
M
S
F
F
L
QTDA
TN
LN
A
-
M
H
H
K
K
P
--
--
N
A
KL
D
TFG
V
FDN
G
WHTLAF
E
FAGNNS
I
QVTPV
L
D
E
K
R
GTPFTL
V
K
SP
A
SG
-
A
ADKL
Q
L
T
G
I
S
KA
A
-
TY
T
L
LIDS
V
K
VEVN
N
A
D
I
AA
fig|655817.3.peg.1231
Escherichia coli ABU 83972 (474-653/653)
T
GGKA
L
Q
L
N
K
P
E
N
---
-
-
HI
W
F
L
E
HD
A
AG
Q
G
V
E
-
LL
K
KGG
R
V
S
V
RFK
L
P
G
S
L
----
V
P
NQ
FALG
I
Y
-
W
Q
L
SSLP
E
GV
T
L
-
A
E
E
GN
D
M
L
M
S
F
F
L
QTDA
TN
LN
A
-
M
H
H
K
K
P
--
--
N
A
KL
D
TFG
V
FDN
G
WHTLAF
E
FAGNNS
I
QVTPV
L
D
E
K
R
GTPFTL
V
K
SP
A
SG
-
A
ADKL
Q
L
T
G
I
S
KA
A
-
TY
T
L
LIDS
V
K
VEVN
N
A
D
I
AA
fig|701177.3.peg.302
Escherichia coli O55:H7 str. CB9615 (441-613/613)
LR
I
V
KE
S
G
---
-
-
K
SW
I
L
S
H
-
-
P
V
K
N
A
S
S
LL
S
R
GG
K
L
T
C
K
F
RL
T
G
A
L
----
T
N
NQ
F
G
LGL
Y
L
Y
TD
A
P
V
P
D
GV
T
I
T
G
-T
G
D
PF
L
M
S
Y
F
T
QT
TDGK
LN
L
-
M
H
H
RK
S
--
-G
N
T
KLG
E
FG
N
Y
S
N
D
W
Q
A
L
ELV
F
TAG-
S
AT
VTP
K
LN
G
VA
G
P
A
F
Q
V
I
K
DS
L
T-
L
G
L
N
A
L
T
L
TD
V
T
KN
A
-
A
Y
G
V
E
I
E
S
L
V
L
E
I
N
A
PA
A
Consen1
Primary consensus
MYGrA
vvsDaeg
GGKAvkltKe
G
---
k
-
sSW
l
ya
-
Ag
gA
-
LLqKGG
I
cRFKv
g
l
----
aNQyvmafY
-
WPVSsLPqgV
L
GdgGnnlLAaFyiQtDAkdLNv
-
MYHna
va
N
KLGtFGAFDneWHtLaFRFAGNNSlqVtPVIDGqdGtpFtL
qsPv
F
ADKL
vTDIT
A
-
TYPVLIdSi
VeVN
tdtAA
Consen2
Secondary consensus
k
itd
sga
lrwe
q
slt
m
hdv
v
e
n
v
i
e
vel
n
falgl
q
--
a
hsm
s
f
s
tn
l
kg
--
s
hn
a
g
i
i
ke
aa
m
kw
n
l
a
e
v
k
ra
Consensus 1
(when a gap)
Conservative difference
Consensus 2
(when a gap)
Nonconservative diff.
Other character