┌─ Escherichia coli (108-192/221) TA280   
                                           ┌┴─ Escherichia coli (112-196/225) M605   
┌──────────────────────────────────────────┴─ Escherichia coli (112-196/225) 55989 (1)  
│┌── Escherichia coli (23-116/141) O157:H7 EDL933 (29)  
││        ┌─ Escherichia coli (2-95/120) 1044A (10)  
││       ┌┴─ Escherichia coli (23-116/141) O157:H7 EDL933 (1)  
┤│      ┌┴─ Escherichia coli (2-95/120) ABU 83972 (1)  
││     ┌┴─ Escherichia coli (2-95/120) F11 (3)  
││    ┌┴┬─ Escherichia coli (2-95/120) FVEC1302 (3)  
││┌───┤ └─ Escherichia coli (23-116/141) ABU 83972 (2)  
└┤│   └┬─ Escherichia coli (23-122/141) 536   
 ││    └┬─── Escherichia coli (27-126/145) F11 (3)  
 ││     └─────────── fig|1040638.4.peg.356 O104:H4 str. LB226692   
 ││          ┌─ fig|1040638.4.peg.979 O104:H4 (24-116/141) str. LB226692   
 ││         ┌┴─ Escherichia coli (23-116/141) ED1a (4)  
 ││        ┌┴┬─ Escherichia coli (23-116/141) EC4100B   
 ││       ┌┤ └─ Escherichia coli (23-116/141) E110019 (1)  
 ││      ┌┤└─ Escherichia coli (2-95/120) O157:H7 str. EC869 (2)  
 └┤     ┌┤└─ Escherichia coli (26-119/144) E110019 (26)  
  │     │└┬─ Escherichia coli (23-116/141) HS (1)  
  │    ┌┤ └┬─ Escherichia coli (23-116/141) B171 (6)  
  │    ││  └─ Escherichia coli (2-95/120) O103:H2 str. 12009 (2)  
  │   ┌┤└─ Escherichia coli (13-97/122) MS 175-1   
  │  ┌┤└─── Escherichia coli (23-111/124) ED1a (1)  
  │┌─┤└─── Escherichia coli (2-101/120) 536 (3)  
  ││ └──┬─── Escherichia coli (2-109/111) M605   
  ││    └─ Escherichia coli (2-93/137) O26:H11 str. 11368   
  └┤                          ┌── Escherichia coli (25-122/125) B088   
   │                         ┌┴─ Escherichia coli (24-125/144) TA280   
   │    ┌────────────────────┴─ fig|6666666.5357.peg.3445 TY-2482 (24-121/144) strain (12)  
   │    │                                           ┌─ fig|1040638.4.peg.210 O104:H4 (23-111/134) str. LB226692 (50)  
   └────┤                                          ┌┴─ Escherichia coli (23-111/134) O26:H11 str. 11368 (1)  
        │                                         ┌┴─ Escherichia coli (23-111/134) H299   
        └───────────────────────────────────┬─────┴─ Escherichia coli (23-111/134) MS 21-1   
                                            └───────────────────┬───── Escherichia coli (35-110/133) NC101   
                                                                └┬─ Escherichia coli (35-125/133) O157:H7 str. EC4196   
                                                                 └┬─ Escherichia coli (35-125/133) O157:H7 (78)  
                                                                  └┬─ Escherichia coli (35-125/133) B7A (134)  
                                                                   └┬─ Escherichia coli (35-125/133) O157:H7 EDL933   
                                                                    └┬─ Escherichia coli (35-110/133) 042 (3)  
                                                                     └┬─ Escherichia coli (35-125/133) B7A (3)  
                                                                      └─ Escherichia coli (35-125/133) S88   
  

  
ISSfl3 orfA
 (19)
  
hypothetical protein
 (8)
  
unknown in ISEc8
 (6)
  
IS, phage, Tn; Transposon-related functions
 (3)
  
Insertion Sequence Associated
 (1)
  
unknown in putative ISEc8
 (1)
  
 Others 
(4)