fig|1040638.4.peg.3461
Escherichia coli O104:H4 str. LB226692
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|6666666.5357.peg.636
Escherichia coli TY-2482
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|216592.1.peg.1495
Escherichia coli 042
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|216592.3.peg.2178
Escherichia coli 042
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|358709.5.peg.4334
Escherichia coli 101-1
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|562.371.peg.4846
Escherichia coli 1044A
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|562.373.peg.402
Escherichia coli 1125A
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|562.372.peg.5223
Escherichia coli 1212A
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|670897.3.peg.2814
Escherichia coli 2362-75
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|362663.8.peg.1895
Escherichia coli 536
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|362663.9.peg.1899
Escherichia coli 536
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|344610.3.peg.4571
Escherichia coli 53638
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|344610.7.peg.4578
Escherichia coli 53638
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|562.374.peg.872
Escherichia coli 536A
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|585055.6.peg.2185
Escherichia coli 55989
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|585055.8.peg.2188
Escherichia coli 55989
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|525281.3.peg.564
Escherichia coli 83972
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|655817.3.peg.2293
Escherichia coli ABU 83972
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|405955.13.peg.2024
Escherichia coli APEC O1
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|405955.9.peg.1660
Escherichia coli APEC O1
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|550676.3.peg.2252
Escherichia coli B185
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|340184.3.peg.3398
Escherichia coli B7A
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|340184.6.peg.3548
Escherichia coli B7A
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|469008.4.peg.1763
Escherichia coli BL21(DE3)
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|595496.3.peg.1902
Escherichia coli BW2952
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|199310.1.peg.2280
Escherichia coli CFT073
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|199310.4.peg.2203
Escherichia coli CFT073
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|536056.3.peg.1812
Escherichia coli DH1
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|340186.3.peg.4365
Escherichia coli E110019
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|340186.5.peg.4588
Escherichia coli E110019
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|216593.1.peg.86
Escherichia coli E2348/69
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|331111.12.peg.2440
Escherichia coli E24377A
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|331111.3.peg.4578
Escherichia coli E24377A
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|562.375.peg.2146
Escherichia coli EC4100B
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|585397.7.peg.2227
Escherichia coli ED1a
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|585397.9.peg.2222
Escherichia coli ED1a
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|316401.4.peg.2331
Escherichia coli ETEC H10407
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|340197.3.peg.3427
Escherichia coli F11
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|340197.5.peg.3594
Escherichia coli F11
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|656379.3.peg.2415
Escherichia coli FVEC1302
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|656380.3.peg.3379
Escherichia coli FVEC1412
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|656393.3.peg.2790
Escherichia coli H299
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|656408.3.peg.2110
Escherichia coli H591
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|656414.3.peg.2284
Escherichia coli H736
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|331112.3.peg.1911
Escherichia coli HS
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|331112.6.peg.1987
Escherichia coli HS
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|585034.4.peg.1994
Escherichia coli IAI1
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|585034.5.peg.1989
Escherichia coli IAI1
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|585057.4.peg.1179
Escherichia coli IAI39
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|585057.6.peg.1175
Escherichia coli IAI39
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|714962.3.peg.2086
Escherichia coli IHE3034
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|83333.1.peg.1910
Escherichia coli K12
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|595495.4.peg.3716
Escherichia coli KO11
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|656417.3.peg.2533
Escherichia coli M605
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|656419.3.peg.2664
Escherichia coli M718
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|749537.3.peg.1145
Escherichia coli MS 115-1
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|749538.3.peg.4554
Escherichia coli MS 116-1
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|679206.4.peg.2070
Escherichia coli MS 119-7
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|679205.4.peg.3745
Escherichia coli MS 124-1
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|749544.3.peg.2332
Escherichia coli MS 175-1
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|749545.3.peg.2905
Escherichia coli MS 182-1
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|749546.3.peg.4645
Escherichia coli MS 185-1
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|749547.3.peg.1293
Escherichia coli MS 187-1
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|749548.3.peg.4862
Escherichia coli MS 196-1
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|749549.3.peg.2959
Escherichia coli MS 198-1
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|749550.3.peg.1984
Escherichia coli MS 200-1
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|749527.3.peg.4854
Escherichia coli MS 21-1
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|749528.3.peg.4916
Escherichia coli MS 45-1
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|749531.3.peg.564
Escherichia coli MS 69-1
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|749532.3.peg.2500
Escherichia coli MS 78-1
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|749533.3.peg.2554
Escherichia coli MS 84-1
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|753642.3.peg.2415
Escherichia coli NC101
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|574521.7.peg.2106
Escherichia coli O127:H6 str. E2348/69
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|83334.1.peg.2688
Escherichia coli O157:H7
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|155864.1.peg.2699
Escherichia coli O157:H7 EDL933
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|155864.8.peg.2570
Escherichia coli O157:H7 EDL933
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|444454.5.peg.1446
Escherichia coli O157:H7 str. EC4024
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|444449.5.peg.934
Escherichia coli O157:H7 str. EC4042
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|444448.5.peg.5222
Escherichia coli O157:H7 str. EC4045
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|444453.5.peg.4609
Escherichia coli O157:H7 str. EC4076
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|444452.5.peg.4748
Escherichia coli O157:H7 str. EC4113
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|444450.8.peg.2733
Escherichia coli O157:H7 str. EC4115
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|444451.5.peg.4806
Escherichia coli O157:H7 str. EC4196
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|444447.5.peg.4764
Escherichia coli O157:H7 str. EC4206
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|478004.5.peg.4837
Escherichia coli O157:H7 str. EC4401
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|478005.5.peg.5125
Escherichia coli O157:H7 str. EC4486
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|478006.5.peg.4752
Escherichia coli O157:H7 str. EC4501
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|478007.5.peg.4856
Escherichia coli O157:H7 str. EC508
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|478008.5.peg.5335
Escherichia coli O157:H7 str. EC869
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|637388.3.peg.4648
Escherichia coli O157:H7 str. FRIK2000
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|570506.3.peg.1659
Escherichia coli O157:H7 str. FRIK966
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|386585.9.peg.2797
Escherichia coli O157:H7 str. Sakai
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|544404.4.peg.2596
Escherichia coli O157:H7 str. TW14359
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|502346.5.peg.4714
Escherichia coli O157:H7 str. TW14588
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|573235.3.peg.2868
Escherichia coli O26:H11 str. 11368
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|701177.3.peg.2388
Escherichia coli O55:H7 str. CB9615
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|685038.3.peg.1948
Escherichia coli O83:H1 str. NRG 857C
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|585035.6.peg.1975
Escherichia coli S88
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|409438.11.peg.2319
Escherichia coli SE11
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|439855.10.peg.1411
Escherichia coli SMS-3-5
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|656437.3.peg.2186
Escherichia coli TA143
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|656443.3.peg.2621
Escherichia coli TA271
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|656444.3.peg.2865
Escherichia coli TA280
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|869729.3.peg.1594
Escherichia coli UM146
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|585056.7.peg.2412
Escherichia coli UMN026
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|364106.7.peg.2166
Escherichia coli UTI89
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|364106.8.peg.2168
Escherichia coli UTI89
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|566546.3.peg.4044
Escherichia coli W
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|566546.4.peg.2093
Escherichia coli W
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|316407.3.peg.1881
Escherichia coli W3110
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|562.376.peg.2170
Escherichia coli WV_060327
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|316385.5.peg.2052
Escherichia coli str. K-12 substr. DH10B
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|316385.7.peg.2099
Escherichia coli str. K-12 substr. DH10B
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|511145.12.peg.2012
Escherichia coli str. K-12 substr. MG1655
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|511145.6.peg.1995
Escherichia coli str. K-12 substr. MG1655
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|481805.3.peg.1837
Escherichia coli ATCC 8739
MKNI
I
PD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|481805.6.peg.1832
Escherichia coli ATCC 8739
MKNI
I
PD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|344601.3.peg.4269
Escherichia coli B171
MKNI
I
PD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|344601.5.peg.4499
Escherichia coli B171
MKNI
I
PD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|340185.3.peg.4752
Escherichia coli E22
MKNI
I
PD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|340185.4.peg.5021
Escherichia coli E22
MKNI
I
PD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|679207.4.peg.3594
Escherichia coli MS 107-1
MKNI
I
PD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|749540.3.peg.2070
Escherichia coli MS 146-1
MKNI
I
PD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|585395.4.peg.2292
Escherichia coli O103:H2 str. 12009
MKNI
I
PD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|550677.3.peg.1467
Escherichia coli B354
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
E
K
fig|550672.3.peg.1673
Escherichia coli B088
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
MS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|679204.3.peg.3083
Escherichia coli MS 145-7
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
MS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|585396.4.peg.2609
Escherichia coli O111:H- str. 11128
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
PQ
L
KK
GE
I
L
E
V
MS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|431946.3.peg.1856
Escherichia coli SE15
MKNIVPD
Y
R
LD
M
VG
EP
CP
Y
P
A
V
ATLE
A
M
LQ
L
KK
GE
I
L
E
V
VS
DCPQ
S
I
NN
IP
LD
A
RNH
G
Y
T
V
L
D
I
QQDG
PTI
RYLI
Q
K
fig|550676.3.peg.2313
Escherichia coli B185 (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AE
M
AS
G
D
K
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|358709.5.peg.462
Escherichia coli 101-1 (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AE
M
TS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|481805.3.peg.1745
Escherichia coli ATCC 8739 (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AE
M
TS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|481805.6.peg.1738
Escherichia coli ATCC 8739 (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AE
M
TS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|1040638.4.peg.3587
Escherichia coli O104:H4 str. LB226692 (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AE
M
AS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|6666666.5357.peg.1282
Escherichia coli TY-2482 (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AE
M
AS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|562.371.peg.4213
Escherichia coli 1044A (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AE
M
AS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|562.373.peg.4676
Escherichia coli 1125A (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AE
M
AS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|562.372.peg.5849
Escherichia coli 1212A (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AE
M
AS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|670888.3.peg.4283
Escherichia coli 1827-70 (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AE
M
AS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|344610.3.peg.2030
Escherichia coli 53638 (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AE
M
AS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|344610.7.peg.4463
Escherichia coli 53638 (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AE
M
AS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|562.374.peg.1722
Escherichia coli 536A (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AE
M
AS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|585055.6.peg.2304
Escherichia coli 55989 (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AE
M
AS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|585055.8.peg.2312
Escherichia coli 55989 (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AE
M
AS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|405955.13.peg.2196
Escherichia coli APEC O1 (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AE
M
AS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|405955.9.peg.1788
Escherichia coli APEC O1 (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AE
M
AS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|413997.3.peg.2009
Escherichia coli B str. REL606 (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AE
M
AS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|550672.3.peg.1734
Escherichia coli B088 (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AE
M
AS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|550677.3.peg.1550
Escherichia coli B354 (5-64/75)
K
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fig|340184.3.peg.2820
Escherichia coli B7A (5-64/75)
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fig|340184.6.peg.2950
Escherichia coli B7A (5-64/75)
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fig|511693.5.peg.2038
Escherichia coli BL21 (5-64/75)
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fig|469008.4.peg.1692
Escherichia coli BL21(DE3) (5-64/75)
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fig|340186.3.peg.4716
Escherichia coli E110019 (5-64/75)
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fig|340186.5.peg.4977
Escherichia coli E110019 (5-64/75)
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fig|331111.12.peg.2584
Escherichia coli E24377A (5-64/75)
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fig|331111.3.peg.46
Escherichia coli E24377A (5-64/75)
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fig|562.375.peg.2231
Escherichia coli EC4100B (5-64/75)
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fig|585397.7.peg.2377
Escherichia coli ED1a (5-64/75)
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fig|585397.9.peg.2375
Escherichia coli ED1a (5-64/75)
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fig|656393.3.peg.3028
Escherichia coli H299 (5-64/75)
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fig|656414.3.peg.2375
Escherichia coli H736 (5-64/75)
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fig|331112.3.peg.2011
Escherichia coli HS (5-64/75)
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fig|331112.6.peg.2104
Escherichia coli HS (5-64/75)
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fig|585034.4.peg.2060
Escherichia coli IAI1 (5-64/75)
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fig|585034.5.peg.2055
Escherichia coli IAI1 (5-64/75)
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fig|585057.4.peg.1056
Escherichia coli IAI39 (5-64/75)
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fig|585057.6.peg.1053
Escherichia coli IAI39 (5-64/75)
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fig|595495.4.peg.3016
Escherichia coli KO11 (5-64/75)
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fig|656419.3.peg.2761
Escherichia coli M718 (5-64/75)
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fig|679207.4.peg.1649
Escherichia coli MS 107-1 (5-64/75)
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fig|749538.3.peg.885
Escherichia coli MS 116-1 (5-64/75)
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fig|679206.4.peg.4492
Escherichia coli MS 119-7 (5-64/75)
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fig|679205.4.peg.5469
Escherichia coli MS 124-1 (5-64/75)
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fig|679204.3.peg.4351
Escherichia coli MS 145-7 (5-64/75)
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fig|749544.3.peg.2025
Escherichia coli MS 175-1 (5-64/75)
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fig|749545.3.peg.4293
Escherichia coli MS 182-1 (5-64/75)
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fig|749547.3.peg.2885
Escherichia coli MS 187-1 (5-64/75)
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fig|749548.3.peg.266
Escherichia coli MS 196-1 (5-64/75)
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fig|749527.3.peg.1578
Escherichia coli MS 21-1 (5-64/75)
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fig|749531.3.peg.998
Escherichia coli MS 69-1 (5-64/75)
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fig|749532.3.peg.3817
Escherichia coli MS 78-1 (5-64/75)
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fig|749533.3.peg.1909
Escherichia coli MS 84-1 (5-64/75)
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fig|585396.4.peg.2830
Escherichia coli O111:H- str. 11128 (5-64/75)
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fig|83334.1.peg.2822
Escherichia coli O157:H7 (5-64/75)
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fig|155864.1.peg.2825
Escherichia coli O157:H7 EDL933 (5-64/75)
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fig|155864.8.peg.2710
Escherichia coli O157:H7 EDL933 (5-64/75)
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fig|444454.5.peg.1679
Escherichia coli O157:H7 str. EC4024 (5-64/75)
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fig|444449.5.peg.1159
Escherichia coli O157:H7 str. EC4042 (5-64/75)
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fig|444448.5.peg.5432
Escherichia coli O157:H7 str. EC4045 (5-64/75)
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fig|444453.5.peg.3651
Escherichia coli O157:H7 str. EC4076 (5-64/75)
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fig|444452.5.peg.4560
Escherichia coli O157:H7 str. EC4113 (5-64/75)
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fig|444450.8.peg.2952
Escherichia coli O157:H7 str. EC4115 (5-64/75)
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fig|444451.5.peg.3123
Escherichia coli O157:H7 str. EC4196 (5-64/75)
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fig|444447.5.peg.52
Escherichia coli O157:H7 str. EC4206 (5-64/75)
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fig|478004.5.peg.4188
Escherichia coli O157:H7 str. EC4401 (5-64/75)
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fig|478005.5.peg.3619
Escherichia coli O157:H7 str. EC4486 (5-64/75)
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fig|478006.5.peg.4443
Escherichia coli O157:H7 str. EC4501 (5-64/75)
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G
fig|478007.5.peg.1882
Escherichia coli O157:H7 str. EC508 (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AE
M
AS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|478008.5.peg.3837
Escherichia coli O157:H7 str. EC869 (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AE
M
AS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|637388.3.peg.2260
Escherichia coli O157:H7 str. FRIK2000 (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AE
M
AS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|570506.3.peg.3406
Escherichia coli O157:H7 str. FRIK966 (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AE
M
AS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|386585.9.peg.2950
Escherichia coli O157:H7 str. Sakai (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AE
M
AS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|544404.4.peg.2814
Escherichia coli O157:H7 str. TW14359 (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AE
M
AS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|502346.5.peg.4568
Escherichia coli O157:H7 str. TW14588 (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AE
M
AS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|573235.3.peg.2986
Escherichia coli O26:H11 str. 11368 (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AE
M
AS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|701177.3.peg.2552
Escherichia coli O55:H7 str. CB9615 (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AE
M
AS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|637912.3.peg.2111
Escherichia coli OP50 (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AE
M
AS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|585035.6.peg.2093
Escherichia coli S88 (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AE
M
AS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|409438.11.peg.2436
Escherichia coli SE11 (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AE
M
AS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|439855.10.peg.1203
Escherichia coli SMS-3-5 (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AE
M
AS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|656443.3.peg.2709
Escherichia coli TA271 (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AE
M
AS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|656444.3.peg.2984
Escherichia coli TA280 (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AE
M
AS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|566546.3.peg.2565
Escherichia coli W (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AE
M
AS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|566546.4.peg.2156
Escherichia coli W (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AE
M
AS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|585396.4.peg.4426
Escherichia coli O111:H- str. 11128 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DG
R
PYRYLIRK
fig|595496.3.peg.1979
Escherichia coli BW2952 (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AE
M
VS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|536056.3.peg.1733
Escherichia coli DH1 (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AE
M
VS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|83333.1.peg.1986
Escherichia coli K12 (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AE
M
VS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|749537.3.peg.3727
Escherichia coli MS 115-1 (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AE
M
VS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|749549.3.peg.2612
Escherichia coli MS 198-1 (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AE
M
VS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|316407.3.peg.1948
Escherichia coli W3110 (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AE
M
VS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|316385.5.peg.2127
Escherichia coli str. K-12 substr. DH10B (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AE
M
VS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|316385.7.peg.2176
Escherichia coli str. K-12 substr. DH10B (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AE
M
VS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|511145.12.peg.2089
Escherichia coli str. K-12 substr. MG1655 (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AE
M
VS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|511145.6.peg.2073
Escherichia coli str. K-12 substr. MG1655 (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AE
M
VS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|1040638.4.peg.2055
Escherichia coli O104:H4 str. LB226692 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|6666666.5357.peg.1883
Escherichia coli TY-2482 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|358709.5.peg.350
Escherichia coli 101-1 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|562.371.peg.3384
Escherichia coli 1044A (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|562.373.peg.1462
Escherichia coli 1125A (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|562.372.peg.4266
Escherichia coli 1212A (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|670888.3.peg.2778
Escherichia coli 1827-70 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|670897.3.peg.3886
Escherichia coli 2362-75 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|362663.8.peg.3598
Escherichia coli 536 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|362663.9.peg.3610
Escherichia coli 536 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|344610.3.peg.136
Escherichia coli 53638 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|344610.7.peg.2764
Escherichia coli 53638 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|562.374.peg.5051
Escherichia coli 536A (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|585055.6.peg.3909
Escherichia coli 55989 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|585055.8.peg.3911
Escherichia coli 55989 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|525281.3.peg.2911
Escherichia coli 83972 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|655817.3.peg.4068
Escherichia coli ABU 83972 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|405955.13.peg.3902
Escherichia coli APEC O1 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|405955.9.peg.3264
Escherichia coli APEC O1 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|481805.3.peg.259
Escherichia coli ATCC 8739 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|481805.6.peg.268
Escherichia coli ATCC 8739 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|413997.3.peg.3477
Escherichia coli B str. REL606 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|344601.3.peg.1303
Escherichia coli B171 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|344601.5.peg.1372
Escherichia coli B171 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|550676.3.peg.3604
Escherichia coli B185 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|550677.3.peg.4021
Escherichia coli B354 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|340184.3.peg.4785
Escherichia coli B7A (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|340184.6.peg.5006
Escherichia coli B7A (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|469008.4.peg.287
Escherichia coli BL21(DE3) (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|595496.3.peg.3452
Escherichia coli BW2952 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|199310.1.peg.4168
Escherichia coli CFT073 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|199310.4.peg.4007
Escherichia coli CFT073 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|536056.3.peg.257
Escherichia coli DH1 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|340186.3.peg.2049
Escherichia coli E110019 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|340186.3.peg.4720
Escherichia coli E110019 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|340186.3.peg.4973
Escherichia coli E110019 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|340186.5.peg.4981
Escherichia coli E110019 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|340185.3.peg.138
Escherichia coli E22 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|340185.4.peg.152
Escherichia coli E22 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|216593.1.peg.4194
Escherichia coli E2348/69 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|331111.12.peg.4192
Escherichia coli E24377A (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|331111.3.peg.1606
Escherichia coli E24377A (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|562.375.peg.4823
Escherichia coli EC4100B (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|585397.7.peg.4134
Escherichia coli ED1a (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|585397.9.peg.4130
Escherichia coli ED1a (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|316401.4.peg.4211
Escherichia coli ETEC H10407 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|340197.3.peg.697
Escherichia coli F11 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|340197.5.peg.723
Escherichia coli F11 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|656408.3.peg.3894
Escherichia coli H591 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|656414.3.peg.3959
Escherichia coli H736 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|331112.3.peg.3440
Escherichia coli HS (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|331112.6.peg.3575
Escherichia coli HS (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|585034.4.peg.3537
Escherichia coli IAI1 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|585034.5.peg.3535
Escherichia coli IAI1 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|585057.4.peg.4085
Escherichia coli IAI39 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|585057.6.peg.4093
Escherichia coli IAI39 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|714962.3.peg.3934
Escherichia coli IHE3034 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|83333.1.peg.3403
Escherichia coli K12 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|595495.4.peg.1436
Escherichia coli KO11 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|656419.3.peg.4446
Escherichia coli M718 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|679207.4.peg.340
Escherichia coli MS 107-1 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|749537.3.peg.624
Escherichia coli MS 115-1 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|749538.3.peg.385
Escherichia coli MS 116-1 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|679206.4.peg.2497
Escherichia coli MS 119-7 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|679205.4.peg.4448
Escherichia coli MS 124-1 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|679204.3.peg.1885
Escherichia coli MS 145-7 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|749540.3.peg.2415
Escherichia coli MS 146-1 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|749544.3.peg.2511
Escherichia coli MS 175-1 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|749545.3.peg.4633
Escherichia coli MS 182-1 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|749546.3.peg.3996
Escherichia coli MS 185-1 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|749547.3.peg.3132
Escherichia coli MS 187-1 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|749548.3.peg.1257
Escherichia coli MS 196-1 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|749550.3.peg.3084
Escherichia coli MS 200-1 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|749527.3.peg.1379
Escherichia coli MS 21-1 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|749528.3.peg.3054
Escherichia coli MS 45-1 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|749531.3.peg.702
Escherichia coli MS 69-1 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|749532.3.peg.4026
Escherichia coli MS 78-1 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|749533.3.peg.5114
Escherichia coli MS 84-1 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|753642.3.peg.4481
Escherichia coli NC101 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|585395.4.peg.4379
Escherichia coli O103:H2 str. 12009 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|83334.1.peg.4289
Escherichia coli O157:H7 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|155864.1.peg.4326
Escherichia coli O157:H7 EDL933 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|155864.8.peg.4270
Escherichia coli O157:H7 EDL933 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|444454.5.peg.3397
Escherichia coli O157:H7 str. EC4024 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|444449.5.peg.2852
Escherichia coli O157:H7 str. EC4042 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|444448.5.peg.1604
Escherichia coli O157:H7 str. EC4045 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|444453.5.peg.1136
Escherichia coli O157:H7 str. EC4076 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|444452.5.peg.206
Escherichia coli O157:H7 str. EC4113 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|444450.8.peg.4686
Escherichia coli O157:H7 str. EC4115 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|444451.5.peg.380
Escherichia coli O157:H7 str. EC4196 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|444447.5.peg.1767
Escherichia coli O157:H7 str. EC4206 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|478004.5.peg.162
Escherichia coli O157:H7 str. EC4401 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|478005.5.peg.127
Escherichia coli O157:H7 str. EC4486 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|478006.5.peg.129
Escherichia coli O157:H7 str. EC4501 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|478007.5.peg.134
Escherichia coli O157:H7 str. EC508 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|478008.5.peg.659
Escherichia coli O157:H7 str. EC869 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|637388.3.peg.1850
Escherichia coli O157:H7 str. FRIK2000 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|570506.3.peg.170
Escherichia coli O157:H7 str. FRIK966 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|386585.9.peg.4512
Escherichia coli O157:H7 str. Sakai (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|544404.4.peg.4496
Escherichia coli O157:H7 str. TW14359 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|502346.5.peg.2331
Escherichia coli O157:H7 str. TW14588 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|573235.3.peg.4669
Escherichia coli O26:H11 str. 11368 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|701177.3.peg.4191
Escherichia coli O55:H7 str. CB9615 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|685038.3.peg.3512
Escherichia coli O83:H1 str. NRG 857C (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|637912.3.peg.67
Escherichia coli OP50 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|585035.6.peg.3797
Escherichia coli S88 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|409438.11.peg.3907
Escherichia coli SE11 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|431946.3.peg.3430
Escherichia coli SE15 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|656437.3.peg.3895
Escherichia coli TA143 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|656440.3.peg.3719
Escherichia coli TA206 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|656443.3.peg.4372
Escherichia coli TA271 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|656444.3.peg.4743
Escherichia coli TA280 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|869729.3.peg.3737
Escherichia coli UM146 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|364106.7.peg.3902
Escherichia coli UTI89 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|364106.8.peg.3903
Escherichia coli UTI89 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|566546.3.peg.1999
Escherichia coli W (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|566546.4.peg.3687
Escherichia coli W (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|316407.3.peg.3658
Escherichia coli W3110 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|562.376.peg.2789
Escherichia coli WV_060327 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|316385.5.peg.3591
Escherichia coli str. K-12 substr. DH10B (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|316385.7.peg.3672
Escherichia coli str. K-12 substr. DH10B (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|511145.12.peg.3569
Escherichia coli str. K-12 substr. MG1655 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|511145.6.peg.3552
Escherichia coli str. K-12 substr. MG1655 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|439855.10.peg.3901
Escherichia coli SMS-3-5 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
DGLPYRYLIRK
fig|656408.3.peg.2208
Escherichia coli H591 (5-62/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AE
M
AS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
fig|344601.3.peg.3100
Escherichia coli B171 (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AG
M
AS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|344601.5.peg.3235
Escherichia coli B171 (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AG
M
AS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|340185.3.peg.1138
Escherichia coli E22 (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AG
M
AS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|340185.4.peg.1202
Escherichia coli E22 (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AG
M
AS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|585395.4.peg.2607
Escherichia coli O103:H2 str. 12009 (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
L
AG
M
AS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|316401.4.peg.2475
Escherichia coli ETEC H10407 (5-64/75)
K
LD
V
V
T
QV
CP
F
P
L
I
EAKA
A
Q
AE
M
VS
G
D
E
L
V
I
EF
DC
T
Q
A
T
EA
IP
QW
A
AEE
GH
A
I
T
D
Y
QQ
I
G
fig|656417.3.peg.4325
Escherichia coli M605 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
G
T
DGLPYRYLIRK
fig|656393.3.peg.4530
Escherichia coli H299 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
D
E
LPYRYLIRK
fig|216592.1.peg.696
Escherichia coli 042 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
D
E
LPYRYLIRK
fig|216592.3.peg.3876
Escherichia coli 042 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
D
E
LPYRYLIRK
fig|656379.3.peg.4749
Escherichia coli FVEC1302 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
D
E
LPYRYLIRK
fig|656380.3.peg.4539
Escherichia coli FVEC1412 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
D
E
LPYRYLIRK
fig|749549.3.peg.2799
Escherichia coli MS 198-1 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
D
E
LPYRYLIRK
fig|585056.7.peg.4107
Escherichia coli UMN026 (8-79/81)
PDH
T
LD
A
L
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QP
GE
T
L
L
I
IA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
K
ET
D
E
LPYRYLIRK
fig|444454.5.peg.762
Escherichia coli O157:H7 str. EC4024 (8-79/80)
PDH
T
LD
A
Q
G
LR
CP
E
P
V
M
MVRK
T
V
RN
M
QS
GE
T
L
L
I
VA
D
D
P
A
TT
RD
IP
GF
C
TFM
E
H
E
L
V
A
Q
Q
T
E
T
LPYRYLIRK
Consen1
Primary consensus
MKNIVPDh
LD
vg
CP
P
m
av
m
Ge
L
i
Dcpqtt
IP
a
gh
l
d
qqdGlpyRYLIrK
Consen2
Secondary consensus
y
lt
t
l
d
v
dta
i
c
ey
a
eti
pti
q
Consensus 1
(when a gap)
Conservative difference
Consensus 2
(when a gap)
Nonconservative diff.
Other character