┌─ Escherichia coli (5-393/394) O157:H7 (27)  
                                                                   ┌┴─ Escherichia coli (4-392/393) E24377A (1)  
                                                                  ┌┴─ Escherichia coli (5-393/394) K12 (12)  
                                                                 ┌┴┬─ Escherichia coli (4-392/393) HS (1)  
                                                                ┌┤ └─ Escherichia coli (4-392/393) 53638 (1)  
                                                                │└┬─ Escherichia coli (4-392/393) 101-1 (18)  
                                                               ┌┤ └┬─ fig|1040638.4.peg.2742 O104:H4 (4-392/393) str. LB226692 (3)  
                                                               ││  └─ Escherichia coli (4-392/393) B354   
                                                               │└─ Escherichia coli (4-392/393) B185 (1)  
                                                              ┌┤  ┌─ Escherichia coli (4-392/393) B171 (12)  
                                                              ││ ┌┴─ Escherichia coli (4-394/395) O111:H- str. 11128   
                                                              │└┬┴─ Escherichia coli (4-392/393) MS 21-1   
                                                              │ └┬─ Escherichia coli (4-392/393) H299 (2)  
                                                             ┌┤  └┬─ Escherichia coli (4-392/393) IAI39 (1)  
                                                             ││   └┬─ Escherichia coli (4-392/393) FVEC1302 (4)  
                                                            ┌┤│    └─ Escherichia coli (4-392/393) 042 (1)  
                                                            ││└─ Escherichia coli (4-392/393) B088 (2)  
                                                           ┌┤└─ Escherichia coli (5-393/394) E2348/69   
                                                           │└┬─ Escherichia coli (4-392/393) MS 200-1   
                                                          ┌┤ └─ Escherichia coli (4-392/393) 536 (3)  
                                                         ┌┤└─ Escherichia coli (4-392/393) 2362-75 (12)  
                                                         │└─ Escherichia coli (4-392/393) UM146   
                                         ┌───────────────┤ ┌─ Escherichia coli (4-392/393) 83972 (1)  
                                         │               └┬┴─ Escherichia coli (4-392/393) MS 45-1   
                              ┌──────────┤                └┬─ Escherichia coli (5-393/394) CFT073 (4)  
                              │          │                 └─ Escherichia coli (4-392/393) MS 185-1   
                              │          └──────────────────┬─ Escherichia coli (4-392/401) E24377A (1)  
                ┌─────────────┤                             └─ Escherichia coli (4-392/401) B7A (5)  
                │             │                         ┌─ Escherichia coli (6-391/394) K12 (19)  
                │             │                         │┌─ Escherichia coli (6-391/394) 53638 (3)  
                │             └─────────────────────────┤│    ┌─ Escherichia coli (6-391/394) MS 69-1   
                │                                       ││   ┌┴─ Escherichia coli (6-391/394) FVEC1302 (4)  
                │                                       ││  ┌┴─ Escherichia coli (6-391/394) B354 (2)  
                │                                       └┤ ┌┴┬─ Escherichia coli (6-391/394) TA280   
                │                                        │ │ └┬─ Escherichia coli (6-391/394) 042   
                │                                        │┌┤  └─ Escherichia coli (6-391/394) M718   
                │                                        ││└┬─ Escherichia coli (6-391/394) MS 21-1   
                │                                        └┤ └─ Escherichia coli (6-391/394) SMS-3-5   
                │                                         │┌─ Escherichia coli (6-391/394) EC4100B (1)  
                │                                         ││  ┌─ Escherichia coli (6-391/394) 83972 (5)  
                │                                         └┤ ┌┴─ Escherichia coli (6-391/394) WV_060327   
                │                                          │┌┴─ Escherichia coli (6-391/394) IHE3034 (4)  
┌───────────────┤                                          └┤ ┌─ Escherichia coli (6-391/394) O83:H1 str. NRG 857C   
│               │                                           └┬┴─ Escherichia coli (6-391/394) 536 (4)  
│               │                                            └┬─ Escherichia coli (6-391/394) M605 (1)  
│               │                                             └┬─ Escherichia coli (6-391/394) H299   
│               │                                              └┬─ Escherichia coli (6-391/394) 2362-75 (2)  
│               │                                               └┬─ Escherichia coli (6-391/394) ED1a (2)  
│               │                                                └─ Escherichia coli (6-391/394) NC101   
│               │                                                 ┌─ Escherichia coli (6-399/401) 1827-70 (7)  
│               │                                                ┌┴─ Escherichia coli (6-399/401) IAI1 (1)  
│               │                                               ┌┴┬─ Escherichia coli (6-399/401) B7A (1)  
│               │                                              ┌┤ └─ Escherichia coli (6-399/401) MS 145-7 (2)  
│               │                                             ┌┤└─ Escherichia coli (6-399/401) B088 (20)  
│               │                                             │└┬─ Escherichia coli (6-399/401) K12 (13)  
│               │          ┌──────────────────────────────────┤ └─ fig|1040638.4.peg.4137 O104:H4 (6-399/401) str. LB226692 (4)  
│               │          │                                  └─ Escherichia coli (6-399/401) O26:H11 str. 11368   
│               └──────────┤                                     ┌── Escherichia coli (2-385/387) O157:H7 str. EC4024   
│                          │                                     │ ┌─ Escherichia coli (2-385/387) TA206   
│                          └─────────────────────────────────────┤ │  ┌─ Escherichia coli (2-385/387) TA143   
│                                                                │ │ ┌┴─ Escherichia coli (2-385/387) SMS-3-5   
│                                                                │ │┌┴─ Escherichia coli (2-385/387) B354   
│                                                                └─┤│      ┌─ Escherichia coli (2-385/387) IAI39 (1)  
│                                                                  ││     ┌┴─ Escherichia coli (2-385/387) MS 21-1   
│                                                                  ││    ┌┴─ Escherichia coli (2-385/387) NC101   
│                                                                  ││   ┌┴─ Escherichia coli (2-385/387) 101-1 (4)  
│                                                                  └┤  ┌┴─ Escherichia coli (2-385/387) UM146 (2)  
│                                                                   │ ┌┴┬─ Escherichia coli (2-385/387) ED1a (1)  
│                                                                   │┌┤ └─ Escherichia coli (2-385/387) APEC O1 (7)  
┤                                                                   ││└┬─ Escherichia coli (2-385/387) 536 (4)  
│                                                                   ││ └┬─ Escherichia coli (2-385/387) 2362-75 (2)  
│                                                                   └┤  └─ Escherichia coli (2-385/387) 83972 (5)  
│                                                                    │ ┌─ Escherichia coli (2-385/387) E110019 (4)  
│                                                                    │┌┴─ fig|1040638.4.peg.1256 O104:H4 (2-385/387) str. LB226692 (4)  
│                                                                    └┤┌─ Escherichia coli (2-385/387) B171 (9)  
│                                                                     └┤┌─ Escherichia coli (2-385/387) E24377A (3)  
│                                                                      ││  ┌─ Escherichia coli (2-385/387) FVEC1302 (3)  
│                                                                      └┤ ┌┴─ Escherichia coli (2-385/387) H299   
│                                                                       │┌┴┬─ Escherichia coli (2-385/387) TA280   
│                                                                       └┤ └─ Escherichia coli (2-385/387) 042 (1)  
│                                                                        │┌─ Escherichia coli (2-385/387) M718   
│                                                                        └┤┌─ Escherichia coli (2-385/387) 1044A (25)  
│                                                                         └┤┌─ Escherichia coli (2-385/387) B185   
│                                                                          └┤┌─ Escherichia coli (2-385/387) 53638 (3)  
│                                                                           └┤┌─ Escherichia coli (2-385/387) O111:H- str. 11128   
│                                                                            └┤ ┌─ Escherichia coli (2-385/387) BW2952 (12)  
│                                                                             └┬┴─ Escherichia coli (2-385/387) K12   
│                                                                              └┬─ Escherichia coli (2-385/387) IAI1 (2)  
│                                                                               └┬─ Escherichia coli (2-385/387) B088   
│                                                                                └─ Escherichia coli (2-385/387) 1827-70 (7)  
│                                                            ┌─ Escherichia coli M718   
│                                                           ┌┴─ Escherichia coli MS 187-1   
│                                                           │   ┌─ Escherichia coli 1044A (23)  
│                                                           │  ┌┴─ Escherichia coli O157:H7 EDL933   
│                                                           │ ┌┴─ Escherichia coli O55:H7 str. CB9615   
│                                                           │┌┴─ Escherichia coli B185   
└───────────────────────────────────────────────────────────┤│       ┌─ Escherichia coli SMS-3-5   
                                                            ││      ┌┴─ Escherichia coli MS 21-1   
                                                            ││     ┌┴─ Escherichia coli B354   
                                                            ││    ┌┴─ Escherichia coli MS 198-1   
                                                            ││   ┌┴─ Escherichia coli FVEC1302 (2)  
                                                            ││  ┌┴┬─ Escherichia coli IAI39 (1)  
                                                            └┤  │ └┬─ Escherichia coli MS 69-1   
                                                             │  │  └┬─ Escherichia coli TA143   
                                                             │ ┌┤   └┬─ Escherichia coli H299   
                                                             │ ││    └─ Escherichia coli 042 (1)  
                                                             │┌┤└─ Escherichia coli 83972 (4)  
                                                             ││└─ Escherichia coli TA280   
                                                             ││      ┌─ Escherichia coli 536 (14)  
                                                             ││     ┌┴─ Escherichia coli ED1a (1)  
                                                             └┤    ┌┴─ Escherichia coli TA206   
                                                              │   ┌┴─ Escherichia coli WV_060327   
                                                              │  ┌┴─ Escherichia coli 2362-75 (1)  
                                                              │ ┌┴─ Escherichia coli M605   
                                                              │┌┴─ Escherichia coli B088   
                                                              └┤ ┌─ Escherichia coli 1827-70   
                                                               │┌┴─ Escherichia coli HS (1)  
                                                               └┤┌─ Escherichia coli EC4100B   
                                                                └┤┌─ Escherichia coli K12 (17)  
                                                                 └┤┌─ Escherichia coli B171 (18)  
                                                                  └┤ ┌─ Escherichia coli E22 (2)  
                                                                   └┬┴─ Escherichia coli MS 124-1 (1)  
                                                                    └┬─ Escherichia coli 53638 (3)  
                                                                     └┬─ Escherichia coli E110019 (1)  
                                                                      └─ fig|1040638.4.peg.3430 O104:H4 str. LB226692 (6)  
  
3-ketoacyl-CoA thiolase (EC 2.3.1.16) @ Acetyl-CoA acetyltransferase (EC 2.3.1.9) (68)
Acetyl-CoA acetyltransferase (EC 2.3.1.9) (46)
Phenylacetic acid degradation protein PaaE, ketothiolase (7)
Others (4)