┬─────────────────────────────────────────────────────────────────── Escherichia coli (16-124/134) APEC O1 (24)  
└──────────────────────────────────────────────────────────────────┬─ Escherichia coli 1044A (39)  
                                                                   └┬─ Escherichia coli K12 (88)  
                                                                    └─ Escherichia coli KO11 (2)  
  

  
Antiholin-like protein LrgA
 (3)
  
Holin-like protein CidA
 (1)