┌─────────────── Escherichia coli ED1a (1)  
│    ┌────────── Escherichia coli (13-179/179) 042 (1)  
┤    │            ┌─ Escherichia coli O26:H11 str. 11368   
│    │  ┌─────────┴────────── Escherichia coli O111:H- str. 11128   
└────┤ ┌┴────────── Escherichia coli TA143   
     │┌┴─ Escherichia coli (13-179/179) HS (61)  
     ││                          ┌───── Escherichia coli H736 (1)  
     ││                     ┌────┴──────────── Escherichia coli str. K-12 substr. DH10B   
     └┤           ┌─────────┴─ Escherichia coli (13-179/179) K12 (9)  
      │ ┌─────────┴─ Escherichia coli (13-179/179) 53638 (7)  
      │┌┴┬──────────── Escherichia coli B088 (1)  
      ││ └─────────┬────────── Escherichia coli MS 145-7   
      └┤           └─ Escherichia coli (13-179/179) B171 (22)  
       │          ┌─ Escherichia coli (13-179/179) E2348/69 (1)  
       │┌─────────┴──────────── Escherichia coli O127:H6 str. E2348/69   
       └┤         ┌─ Escherichia coli B354   
        └─────────┤         ┌─ Escherichia coli TA280   
                  └─────────┤          ┌─ Escherichia coli (13-179/179) CFT073 (6)  
                            └─────────┬┴────────── Escherichia coli MS 69-1   
                                      └───────────────────┬──────────── Escherichia coli FVEC1412 (1)  
                                                          └─ Escherichia coli FVEC1302 (1)  
  

  
COG1451: Predicted metal-dependent hydrolase
 (21)