┌─────────────── Escherichia coli 536 (1)  
                  ┌┴────────── Escherichia coli SMS-3-5   
   ┌──────────────┴───── Escherichia coli F11 (2)  
  ┌┴─────────┬───────────────────────── Escherichia coli B354   
  │          └───────────────────┬─────────────────────────────────── Escherichia coli M605   
┌─┤                              └───── Escherichia coli SE15   
│ └───────────────────┬───────────────────────── Escherichia coli (52-1081/1081) 042 (2)  
│                     └┬─────────────── Escherichia coli MS 69-1   
│                      └───── Escherichia coli FVEC1302 (3)  
│                                          ┌───── Escherichia coli 2362-75 (2)  
│                                     ┌────┴───── Escherichia coli TA206   
┤                                 ┌───┴┬────────── Escherichia coli APEC O1 (1)  
│             ┌───────────────────┤    └─ Escherichia coli ED1a (6)  
│             │                   └┬────────── Escherichia coli 83972 (5)  
│   ┌─────────┤                    └────┬────────── Escherichia coli O83:H1 str. NRG 857C   
│   │         │                         └─ Escherichia coli NC101   
│  ┌┤         └────────── Escherichia coli WV_060327   
│  │└─────────────── Escherichia coli H299   
└──┤     ┌───── Escherichia coli MS 124-1 (1)  
   │┌────┴──────────────────── Escherichia coli B185   
   ││              ┌─ Escherichia coli ATCC 8739 (1)  
   └┤         ┌────┴───── Escherichia coli 53638 (1)  
    │    ┌────┴────────── Escherichia coli IAI39 (1)  
    └────┤┌──────────────────── Escherichia coli TA280   
         ││              ┌───── Escherichia coli 1827-70   
         └┤    ┌─────────┴───── Escherichia coli HS (1)  
          │    │         ┌─ Escherichia coli MS 187-1   
          └────┤    ┌────┴─────────────── Escherichia coli MS 115-1   
               │    │          ┌─ Escherichia coli 1044A (23)  
               │    │     ┌────┴─ Escherichia coli O157:H7 EDL933   
               └────┤┌────┴─ Escherichia coli O55:H7 str. CB9615   
                    ││                 ┌─ Escherichia coli 101-1 (9)  
                    ││                ┌┴───── Escherichia coli H736 (1)  
                    └┤           ┌────┴─────────────── Escherichia coli K12   
                     │ ┌─────────┴────┬───── Escherichia coli OP50   
                     │┌┤              └─ Escherichia coli B str. REL606 (2)  
                     ││└──────────────────── Escherichia coli M718   
                     └┤          ┌─ Escherichia coli EC4100B (1)  
                      │     ┌────┴───── Escherichia coli O111:H- str. 11128   
                      └────┬┴─ Escherichia coli B088 (6)  
                           └┬───── Escherichia coli B7A (1)  
                            └────┬─ Escherichia coli TA271   
                                 └────┬────────── Escherichia coli E24377A (1)  
                                      └┬───── Escherichia coli O103:H2 str. 12009   
                                       └┬───── fig|1040638.4.peg.2230 O104:H4 str. LB226692   
                                        └┬─ fig|6666666.5357.peg.4456 TY-2482 strain (12)  
                                         └────────── Escherichia coli IAI1 (1)  
  

  
Evolved beta-D-galactosidase, alpha subunit
 (45)
  
 Others 
(2)