fig|1040638.4.peg.1955
Escherichia coli O104:H4 str. LB226692
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|6666666.5357.peg.1478
Escherichia coli TY-2482
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|216592.1.peg.603
Escherichia coli 042
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|216592.3.peg.3788
Escherichia coli 042
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|358709.5.peg.4214
Escherichia coli 101-1
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|562.371.peg.3488
Escherichia coli 1044A
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|562.373.peg.1357
Escherichia coli 1125A
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|562.372.peg.4370
Escherichia coli 1212A
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|670888.3.peg.2865
Escherichia coli 1827-70
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|670897.3.peg.3975
Escherichia coli 2362-75
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|362663.8.peg.3497
Escherichia coli 536
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|362663.9.peg.3509
Escherichia coli 536
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|344610.3.peg.223
Escherichia coli 53638
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|344610.7.peg.2854
Escherichia coli 53638
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|562.374.peg.4948
Escherichia coli 536A
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|585055.6.peg.3818
Escherichia coli 55989
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|585055.8.peg.3820
Escherichia coli 55989
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|525281.3.peg.2810
Escherichia coli 83972
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|655817.3.peg.3960
Escherichia coli ABU 83972
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|405955.13.peg.3799
Escherichia coli APEC O1
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|405955.9.peg.3180
Escherichia coli APEC O1
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|481805.3.peg.349
Escherichia coli ATCC 8739
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|481805.6.peg.356
Escherichia coli ATCC 8739
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|413997.3.peg.3388
Escherichia coli B str. REL606
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|550672.3.peg.3427
Escherichia coli B088
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|344601.3.peg.1213
Escherichia coli B171
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|344601.5.peg.1278
Escherichia coli B171
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|550676.3.peg.3512
Escherichia coli B185
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|550677.3.peg.3929
Escherichia coli B354
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|340184.3.peg.2993
Escherichia coli B7A
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|340184.6.peg.3126
Escherichia coli B7A
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|511693.5.peg.3401
Escherichia coli BL21
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|469008.4.peg.378
Escherichia coli BL21(DE3)
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|595496.3.peg.3361
Escherichia coli BW2952
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|199310.1.peg.4063
Escherichia coli CFT073
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|199310.4.peg.3905
Escherichia coli CFT073
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|536056.3.peg.346
Escherichia coli DH1
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|340186.3.peg.1957
Escherichia coli E110019
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|340186.5.peg.2022
Escherichia coli E110019
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|340185.3.peg.227
Escherichia coli E22
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|340185.4.peg.243
Escherichia coli E22
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|216593.1.peg.4104
Escherichia coli E2348/69
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|331111.12.peg.4101
Escherichia coli E24377A
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|331111.3.peg.1517
Escherichia coli E24377A
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|562.375.peg.4720
Escherichia coli EC4100B
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|585397.7.peg.4032
Escherichia coli ED1a
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|585397.9.peg.4028
Escherichia coli ED1a
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|316401.4.peg.4119
Escherichia coli ETEC H10407
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|340197.3.peg.1649
Escherichia coli F11
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|340197.5.peg.1742
Escherichia coli F11
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|656379.3.peg.4655
Escherichia coli FVEC1302
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|656380.3.peg.4446
Escherichia coli FVEC1412
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|656393.3.peg.4432
Escherichia coli H299
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|656408.3.peg.3798
Escherichia coli H591
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|331112.3.peg.3354
Escherichia coli HS
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|331112.6.peg.3486
Escherichia coli HS
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|585034.4.peg.3444
Escherichia coli IAI1
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|585034.5.peg.3442
Escherichia coli IAI1
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|585057.4.peg.3992
Escherichia coli IAI39
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|585057.6.peg.4000
Escherichia coli IAI39
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|714962.3.peg.3831
Escherichia coli IHE3034
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|83333.1.peg.3321
Escherichia coli K12
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|595495.4.peg.1535
Escherichia coli KO11
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|656417.3.peg.4221
Escherichia coli M605
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|656419.3.peg.4347
Escherichia coli M718
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|679207.4.peg.434
Escherichia coli MS 107-1
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|749537.3.peg.2929
Escherichia coli MS 115-1
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|749538.3.peg.476
Escherichia coli MS 116-1
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|679206.4.peg.2594
Escherichia coli MS 119-7
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|679205.4.peg.787
Escherichia coli MS 124-1
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|679204.3.peg.1791
Escherichia coli MS 145-7
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|749540.3.peg.2323
Escherichia coli MS 146-1
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|749544.3.peg.2417
Escherichia coli MS 175-1
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|749545.3.peg.4529
Escherichia coli MS 182-1
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|749546.3.peg.4104
Escherichia coli MS 185-1
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|749547.3.peg.3229
Escherichia coli MS 187-1
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|749548.3.peg.1646
Escherichia coli MS 196-1
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|749549.3.peg.832
Escherichia coli MS 198-1
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|749550.3.peg.2979
Escherichia coli MS 200-1
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|749527.3.peg.2135
Escherichia coli MS 21-1
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|749528.3.peg.823
Escherichia coli MS 45-1
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|749531.3.peg.1178
Escherichia coli MS 69-1
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|749532.3.peg.3930
Escherichia coli MS 78-1
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|749533.3.peg.5205
Escherichia coli MS 84-1
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|753642.3.peg.4583
Escherichia coli NC101
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|585395.4.peg.4288
Escherichia coli O103:H2 str. 12009
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|585396.4.peg.4337
Escherichia coli O111:H- str. 11128
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|574521.7.peg.3709
Escherichia coli O127:H6 str. E2348/69
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|83334.1.peg.4202
Escherichia coli O157:H7
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|155864.1.peg.4233
Escherichia coli O157:H7 EDL933
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|155864.8.peg.4171
Escherichia coli O157:H7 EDL933
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|444454.5.peg.3299
Escherichia coli O157:H7 str. EC4024
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|444449.5.peg.2755
Escherichia coli O157:H7 str. EC4042
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|444448.5.peg.1506
Escherichia coli O157:H7 str. EC4045
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|444453.5.peg.1038
Escherichia coli O157:H7 str. EC4076
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|444452.5.peg.4692
Escherichia coli O157:H7 str. EC4113
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|444450.8.peg.4588
Escherichia coli O157:H7 str. EC4115
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|444451.5.peg.478
Escherichia coli O157:H7 str. EC4196
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|444447.5.peg.1669
Escherichia coli O157:H7 str. EC4206
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|478004.5.peg.64
Escherichia coli O157:H7 str. EC4401
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|478005.5.peg.33
Escherichia coli O157:H7 str. EC4486
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|478006.5.peg.32
Escherichia coli O157:H7 str. EC4501
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|478007.5.peg.37
Escherichia coli O157:H7 str. EC508
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|478008.5.peg.560
Escherichia coli O157:H7 str. EC869
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|637388.3.peg.1752
Escherichia coli O157:H7 str. FRIK2000
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|570506.3.peg.268
Escherichia coli O157:H7 str. FRIK966
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|386585.9.peg.4414
Escherichia coli O157:H7 str. Sakai
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|544404.4.peg.4398
Escherichia coli O157:H7 str. TW14359
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|502346.5.peg.2428
Escherichia coli O157:H7 str. TW14588
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|573235.3.peg.4581
Escherichia coli O26:H11 str. 11368
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|701177.3.peg.4095
Escherichia coli O55:H7 str. CB9615
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|685038.3.peg.3417
Escherichia coli O83:H1 str. NRG 857C
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|637912.3.peg.2675
Escherichia coli OP50
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|585035.6.peg.3695
Escherichia coli S88
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|409438.11.peg.3814
Escherichia coli SE11
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|431946.3.peg.3341
Escherichia coli SE15
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|439855.10.peg.3811
Escherichia coli SMS-3-5
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|656437.3.peg.3799
Escherichia coli TA143
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|656440.3.peg.3619
Escherichia coli TA206
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|656443.3.peg.4274
Escherichia coli TA271
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|656444.3.peg.4645
Escherichia coli TA280
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|869729.3.peg.3628
Escherichia coli UM146
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|585056.7.peg.4015
Escherichia coli UMN026
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|364106.7.peg.3800
Escherichia coli UTI89
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|364106.8.peg.3802
Escherichia coli UTI89
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|566546.3.peg.2096
Escherichia coli W
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|566546.4.peg.3594
Escherichia coli W
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|316407.3.peg.3740
Escherichia coli W3110
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|316385.5.peg.3507
Escherichia coli str. K-12 substr. DH10B
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|316385.7.peg.3583
Escherichia coli str. K-12 substr. DH10B
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|511145.12.peg.3479
Escherichia coli str. K-12 substr. MG1655
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|511145.6.peg.3463
Escherichia coli str. K-12 substr. MG1655
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|656414.3.peg.3866
Escherichia coli H736
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
G
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
A
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGADMFVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|562.376.peg.309
Escherichia coli WV_060327
MKQYLI
A
PSI
L
SAD
F
ARLGEDT
A
K
ALAAG
AD
VV
H
F
DVMDNHYVPNLT
I
GP
MV
L
KS
LRN
YG
IT
A
PIDVHLMV
K
PVDR
I
V
P
DFA
A
AGA
SI
IT
F
HPEA
-
S
E
HV
D
RTLQLIK
EN
D
C
KAGLVFNPATPL
S
YLDY
V
MDKLD
V
ILLMSVNPGF
G
GQ
S
FIPQTLDKLREVR
RR
I
D
E
S
G
F
DIRLEVDGGVK
V
NN
IG
EIAAAGAD
I
FVAG
-
SAIFD
-
QPDYKKVIDEMRSELAKVSHE
fig|685038.3.peg.2032
Escherichia coli O83:H1 str. NRG 857C (4-202/214)
I
L
PSI
F
G
AD
I
L
RL
K
DE
I
H
F
LEEEQ
T
E
IL
H
V
D
L
MD
G
T
YV
S
N
I
A
F
GP
NQ
I
AA
M
KK
AS
-
S
M
IF
DVH
M
M
L
A
N
P
E
R
H
I
D
D
VI
N
T
GA
EM
I
S
V
H
Y
E
S
-
T
P
HV
H
YI
I
Q
K
IK
KA
G
R
KAG
V
V
L
NP
G
TP
E
S
V
IE
Y
L
L
D
D
I
D
Y
ILLM
T
I
NPG
Q
P
GQ
T
FI
H
KS
L
E
K
I
R
NT
K
KM
I
-
-
S
G
R
DI
Q
I
EVDGGV
N
L
D
N
VK
QV
KE
AGAD
L
I
V
V
G
-
G
A
L
F
N
K
QP
fig|562.376.peg.1011
Escherichia coli WV_060327 (4-202/214)
I
L
PSI
F
G
AD
I
L
RL
K
DE
I
H
F
LEEEQ
T
E
IL
H
V
D
L
MD
G
T
YV
S
N
I
A
F
GP
NQ
I
AA
M
KK
AS
-
S
M
IF
DVH
M
M
L
A
N
P
E
R
H
I
D
D
VI
N
T
GA
EM
I
S
V
H
Y
E
S
-
T
P
HV
H
YI
I
Q
K
IK
KA
G
R
KAG
V
V
L
NP
G
TP
E
S
V
IE
Y
L
L
D
D
I
D
Y
ILLM
T
I
NPG
Q
P
GQ
T
FI
H
KS
L
E
K
I
R
NT
K
KM
I
-
-
S
G
R
DI
Q
I
EVDGGV
N
L
D
N
VK
QV
KE
AGAD
L
I
V
V
G
-
G
A
L
F
N
K
QP
fig|481805.3.peg.1765
Escherichia coli ATCC 8739 (4-202/214)
I
L
PSI
F
G
AD
I
L
RL
K
DE
I
H
F
LEEEQ
T
E
IL
H
V
D
L
MD
G
T
YV
S
N
I
A
F
GP
NQ
I
AA
M
KK
AS
-
S
M
IF
DVH
M
M
L
A
N
P
E
R
H
I
D
D
VI
N
T
GA
EM
I
S
V
H
Y
E
S
-
T
P
HV
H
YI
I
Q
K
IK
KA
G
R
KAG
V
V
L
NP
G
TP
E
S
V
IE
Y
L
L
D
D
I
D
Y
ILLM
T
I
NPG
Q
P
GQ
T
FI
H
KS
L
E
K
I
R
NT
K
KM
I
-
-
S
G
K
DI
Q
I
EVDGGV
N
L
D
N
VK
QV
KE
AGAD
L
I
V
V
G
-
G
A
L
F
N
K
QP
fig|481805.6.peg.1759
Escherichia coli ATCC 8739 (4-202/214)
I
L
PSI
F
G
AD
I
L
RL
K
DE
I
H
F
LEEEQ
T
E
IL
H
V
D
L
MD
G
T
YV
S
N
I
A
F
GP
NQ
I
AA
M
KK
AS
-
S
M
IF
DVH
M
M
L
A
N
P
E
R
H
I
D
D
VI
N
T
GA
EM
I
S
V
H
Y
E
S
-
T
P
HV
H
YI
I
Q
K
IK
KA
G
R
KAG
V
V
L
NP
G
TP
E
S
V
IE
Y
L
L
D
D
I
D
Y
ILLM
T
I
NPG
Q
P
GQ
T
FI
H
KS
L
E
K
I
R
NT
K
KM
I
-
-
S
G
K
DI
Q
I
EVDGGV
N
L
D
N
VK
QV
KE
AGAD
L
I
V
V
G
-
G
A
L
F
N
K
QP
fig|749527.3.peg.2949
Escherichia coli MS 21-1 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
T
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
G
M
K
M
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDKL
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|525281.3.peg.1784
Escherichia coli 83972 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
S
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
G
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDK
V
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|655817.3.peg.4832
Escherichia coli ABU 83972 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
S
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
G
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDK
V
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|405955.13.peg.4586
Escherichia coli APEC O1 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
S
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
G
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDK
V
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|405955.9.peg.3873
Escherichia coli APEC O1 (14-215/242)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
S
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
G
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDK
V
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|199310.1.peg.4985
Escherichia coli CFT073 (5-206/233)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
S
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
G
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDK
V
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|199310.4.peg.4775
Escherichia coli CFT073 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
S
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
G
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDK
V
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|585397.7.peg.4806
Escherichia coli ED1a (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
S
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
G
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDK
V
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|585397.9.peg.4806
Escherichia coli ED1a (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
S
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
G
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDK
V
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|714962.3.peg.4624
Escherichia coli IHE3034 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
S
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
G
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDK
V
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|749546.3.peg.1647
Escherichia coli MS 185-1 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
S
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
G
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDK
V
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|749528.3.peg.3774
Escherichia coli MS 45-1 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
S
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
G
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDK
V
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|753642.3.peg.4051
Escherichia coli NC101 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
S
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
G
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDK
V
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|685038.3.peg.4187
Escherichia coli O83:H1 str. NRG 857C (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
S
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
G
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDK
V
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|585035.6.peg.4485
Escherichia coli S88 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
S
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
G
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDK
V
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|431946.3.peg.4126
Escherichia coli SE15 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
S
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
G
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDK
V
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|656440.3.peg.4669
Escherichia coli TA206 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
S
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
G
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDK
V
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|869729.3.peg.4436
Escherichia coli UM146 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
S
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
G
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDK
V
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|364106.7.peg.4560
Escherichia coli UTI89 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
S
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
G
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDK
V
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|364106.8.peg.4559
Escherichia coli UTI89 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
S
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
G
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDK
V
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|562.376.peg.1754
Escherichia coli WV_060327 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
S
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
G
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDK
V
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|358709.5.peg.1834
Escherichia coli 101-1 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
T
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
D
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDKL
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|670888.3.peg.4653
Escherichia coli 1827-70 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
T
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
D
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDKL
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|344610.3.peg.1357
Escherichia coli 53638 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
T
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
D
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDKL
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|344610.7.peg.2047
Escherichia coli 53638 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
T
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
D
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDKL
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|481805.3.peg.4235
Escherichia coli ATCC 8739 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
T
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
D
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDKL
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|481805.6.peg.4220
Escherichia coli ATCC 8739 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
T
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
D
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDKL
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|413997.3.peg.4174
Escherichia coli B str. REL606 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
T
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
D
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDKL
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|511693.5.peg.4195
Escherichia coli BL21 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
T
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
D
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDKL
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|469008.4.peg.4095
Escherichia coli BL21(DE3) (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
T
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
D
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDKL
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|595496.3.peg.4158
Escherichia coli BW2952 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
T
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
D
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDKL
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|536056.3.peg.4148
Escherichia coli DH1 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
T
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
D
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDKL
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|316401.4.peg.4992
Escherichia coli ETEC H10407 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
T
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
D
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDKL
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|656414.3.peg.4642
Escherichia coli H736 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
T
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
D
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDKL
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|585057.4.peg.4649
Escherichia coli IAI39 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
T
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
D
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDKL
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|585057.6.peg.4658
Escherichia coli IAI39 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
T
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
D
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDKL
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|83333.1.peg.3997
Escherichia coli K12 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
T
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
D
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDKL
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|595495.4.peg.4804
Escherichia coli KO11 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
T
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
D
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDKL
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|749538.3.peg.296
Escherichia coli MS 116-1 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
T
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
D
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDKL
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|749540.3.peg.728
Escherichia coli MS 146-1 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
T
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
D
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDKL
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|749544.3.peg.3121
Escherichia coli MS 175-1 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
T
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
D
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDKL
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|749547.3.peg.4132
Escherichia coli MS 187-1 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
T
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
D
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDKL
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|749548.3.peg.404
Escherichia coli MS 196-1 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
T
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
D
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDKL
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|637912.3.peg.2878
Escherichia coli OP50 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
T
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
D
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDKL
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|409438.11.peg.4565
Escherichia coli SE11 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
T
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
D
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDKL
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|316407.3.peg.3923
Escherichia coli W3110 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
T
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
D
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDKL
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|316385.7.peg.4317
Escherichia coli str. K-12 substr. DH10B (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
T
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
D
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDKL
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|511145.12.peg.4211
Escherichia coli str. K-12 substr. MG1655 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
T
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
D
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDKL
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|511145.6.peg.4193
Escherichia coli str. K-12 substr. MG1655 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
T
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
D
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDKL
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|656393.3.peg.198
Escherichia coli H299 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DNH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
S
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
G
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDK
V
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|344601.3.peg.1113
Escherichia coli B171 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
T
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
CH
D
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDKL
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|344601.5.peg.1178
Escherichia coli B171 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
T
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
CH
D
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDKL
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|340184.3.peg.3861
Escherichia coli B7A (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
T
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
CH
D
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDKL
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|340184.6.peg.4035
Escherichia coli B7A (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
T
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
CH
D
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDKL
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|340185.3.peg.1375
Escherichia coli E22 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
T
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
CH
D
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDKL
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|340185.4.peg.1458
Escherichia coli E22 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
T
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
CH
D
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDKL
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|679204.3.peg.3027
Escherichia coli MS 145-7 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
T
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
CH
D
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDKL
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|585395.4.peg.5079
Escherichia coli O103:H2 str. 12009 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
T
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
CH
D
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDKL
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|439855.10.peg.4664
Escherichia coli SMS-3-5 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
S
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
D
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDKL
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|670897.3.peg.1403
Escherichia coli 2362-75 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DNH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
S
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
G
M
K
V
GL
IL
NP
E
TP
V
D
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDK
V
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
V
T
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|216593.1.peg.3920
Escherichia coli E2348/69 (14-215/242)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DNH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
S
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
G
M
K
V
GL
IL
NP
E
TP
V
D
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDK
V
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
V
T
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|362663.8.peg.4361
Escherichia coli 536 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
S
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
C
RH
G
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDK
V
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|362663.9.peg.4377
Escherichia coli 536 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
S
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
C
RH
G
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDK
V
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|340197.3.peg.2112
Escherichia coli F11 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
S
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
C
RH
G
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDK
V
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|340197.5.peg.2225
Escherichia coli F11 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
S
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
C
RH
G
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDK
V
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|749550.3.peg.4403
Escherichia coli MS 200-1 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
S
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
C
RH
G
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDK
V
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|656417.3.peg.5170
Escherichia coli M605 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
S
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
RH
G
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
GQ
P
FIP
E
M
LDK
V
A
E
LK
AW
R
E
R
K
D
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|679205.4.peg.1298
Escherichia coli MS 124-1 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
T
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
CH
D
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
R
Q
P
FIP
E
M
LDKL
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|749533.3.peg.4327
Escherichia coli MS 84-1 (3-204/231)
I
S
PS
L
M
CM
D
L
LKFK
E
Q
I
E
F
I-DSH
AD
YF
H
I
D
I
MD
G
H
F
VPNLT
L
S
P
FF
V
SQ
VKK
LA
-
T
K
P
L
D
C
HLMV
T
RPQD
Y
I
A
QL
A
R
AGA
DF
IT
L
HPE
TI
N
G
QA
F
R
LIDE
I
R
CH
D
M
K
V
GL
IL
NP
E
TP
V
E
A
M
K
Y
Y
I
H
K
A
D
K
I
TV
M
T
V
D
PGF
A
R
Q
P
FIP
E
M
LDKL
A
E
LK
AW
R
E
R
E
G
L
EYEI
EVDG
SCN
Q
AT
YE
K
LM
AAGAD
V
F
IV
G
T
S
GL
F
NHAE
fig|679204.3.peg.5125
Escherichia coli MS 145-7 (2-206/210)
I
L
H
PS
L
A
SA
N
P
L
HY
G
R
E
L
T
A
LDNLD
FG
SL
H
L
D
I
E
D
S
SF
I
N
N
I
T
F
G
M
KT
V
QA
V
AR
QT
-
P
H
P
L
SF
H
F
MV
A
RPQ
R
W
F
N
A
L
A
E
I
RP
AW
I
F
V
H
A
E
T
-
L
D
Y
P
S
E
TL
T
E
I
R
HT
G
A
R
AGLVFNPATP
I
D
A
WR
Y
L
AS
E
LD
G
VM
V
M
TS
E
P
D
G
Q
GQ
R
FIP
S
M
C
E
K
IQ
K
VR
TA
F
P
Q
T
-
-
--
E
CWA
DGG
I
T
L
A
A
AQ
Q
L
AAAGA
QH
M
V
I
G
-
R
A
L
F
S
-
SS
DY
RATLAQ
fig|431946.3.peg.4413
Escherichia coli SE15 (2-206/210)
I
L
H
PS
L
A
SA
N
P
L
HY
G
R
E
L
T
A
LDNLD
FG
SL
H
L
D
I
E
D
S
SF
I
N
N
I
T
F
G
M
KT
V
QA
V
AR
QT
-
P
H
P
L
SF
H
F
MV
A
RPQ
R
W
F
N
A
L
A
E
I
RP
AW
I
F
V
H
A
E
T
-
L
D
Y
P
S
E
TL
T
E
I
R
HT
G
A
R
AGLVFNPATP
I
D
A
WR
Y
L
AS
E
LD
G
VM
V
M
TS
E
P
D
G
Q
GQ
R
FIP
S
M
C
E
K
IQ
K
VR
TA
F
P
Q
T
-
-
--
E
CWA
DGG
I
T
L
A
A
AQ
Q
L
AAAGA
QH
M
V
I
G
-
R
A
L
F
S
-
SS
DY
RATLAQ
fig|670888.3.peg.454
Escherichia coli 1827-70 (2-206/210)
I
L
H
PS
L
A
SA
N
P
L
HY
G
R
E
L
T
A
LDNLD
FG
SL
H
L
D
I
E
D
S
SF
I
N
N
I
T
F
G
M
KT
V
QA
V
AR
QT
-
P
H
P
L
SF
H
F
M
L
A
RPQ
R
W
F
N
A
L
A
E
I
RP
AW
I
F
V
H
A
E
T
-
L
D
Y
P
S
E
TL
T
E
I
R
HT
G
A
R
AGLVFNPATP
I
D
A
WR
Y
L
AS
E
LD
G
VM
V
M
TS
E
P
D
G
Q
GQ
R
FIP
S
M
C
E
K
IQ
K
VR
TA
F
P
Q
T
-
-
--
E
CWA
DGG
I
T
L
A
A
AQ
Q
L
AAAGA
QH
M
V
I
G
-
R
A
L
F
S
-
SS
DY
RATLAQ
fig|413997.3.peg.4398
Escherichia coli B str. REL606 (2-206/210)
I
L
H
PS
L
A
SA
N
P
L
HY
G
R
E
L
T
A
LDNLD
FG
SL
H
L
D
I
E
D
S
SF
I
N
N
I
T
F
G
M
KT
V
QA
V
AR
QT
-
P
H
P
L
SF
H
F
M
L
A
RPQ
R
W
F
N
A
L
A
E
I
RP
AW
I
F
V
H
A
E
T
-
L
D
Y
P
S
E
TL
T
E
I
R
HT
G
A
R
AGLVFNPATP
I
D
A
WR
Y
L
AS
E
LD
G
VM
V
M
TS
E
P
D
G
Q
GQ
R
FIP
S
M
C
E
K
IQ
K
VR
TA
F
P
Q
T
-
-
--
E
CWA
DGG
I
T
L
A
A
AQ
Q
L
AAAGA
QH
M
V
I
G
-
R
A
L
F
S
-
SS
DY
RATLAQ
fig|511693.5.peg.4421
Escherichia coli BL21 (2-206/210)
I
L
H
PS
L
A
SA
N
P
L
HY
G
R
E
L
T
A
LDNLD
FG
SL
H
L
D
I
E
D
S
SF
I
N
N
I
T
F
G
M
KT
V
QA
V
AR
QT
-
P
H
P
L
SF
H
F
M
L
A
RPQ
R
W
F
N
A
L
A
E
I
RP
AW
I
F
V
H
A
E
T
-
L
D
Y
P
S
E
TL
T
E
I
R
HT
G
A
R
AGLVFNPATP
I
D
A
WR
Y
L
AS
E
LD
G
VM
V
M
TS
E
P
D
G
Q
GQ
R
FIP
S
M
C
E
K
IQ
K
VR
TA
F
P
Q
T
-
-
--
E
CWA
DGG
I
T
L
A
A
AQ
Q
L
AAAGA
QH
M
V
I
G
-
R
A
L
F
S
-
SS
DY
RATLAQ
fig|469008.4.peg.3872
Escherichia coli BL21(DE3) (2-206/210)
I
L
H
PS
L
A
SA
N
P
L
HY
G
R
E
L
T
A
LDNLD
FG
SL
H
L
D
I
E
D
S
SF
I
N
N
I
T
F
G
M
KT
V
QA
V
AR
QT
-
P
H
P
L
SF
H
F
M
L
A
RPQ
R
W
F
N
A
L
A
E
I
RP
AW
I
F
V
H
A
E
T
-
L
D
Y
P
S
E
TL
T
E
I
R
HT
G
A
R
AGLVFNPATP
I
D
A
WR
Y
L
AS
E
LD
G
VM
V
M
TS
E
P
D
G
Q
GQ
R
FIP
S
M
C
E
K
IQ
K
VR
TA
F
P
Q
T
-
-
--
E
CWA
DGG
I
T
L
A
A
AQ
Q
L
AAAGA
QH
M
V
I
G
-
R
A
L
F
S
-
SS
DY
RATLAQ
fig|595496.3.peg.4381
Escherichia coli BW2952 (2-206/210)
I
L
H
PS
L
A
SA
N
P
L
HY
G
R
E
L
T
A
LDNLD
FG
SL
H
L
D
I
E
D
S
SF
I
N
N
I
T
F
G
M
KT
V
QA
V
AR
QT
-
P
H
P
L
SF
H
F
M
L
A
RPQ
R
W
F
N
A
L
A
E
I
RP
AW
I
F
V
H
A
E
T
-
L
D
Y
P
S
E
TL
T
E
I
R
HT
G
A
R
AGLVFNPATP
I
D
A
WR
Y
L
AS
E
LD
G
VM
V
M
TS
E
P
D
G
Q
GQ
R
FIP
S
M
C
E
K
IQ
K
VR
TA
F
P
Q
T
-
-
--
E
CWA
DGG
I
T
L
A
A
AQ
Q
L
AAAGA
QH
M
V
I
G
-
R
A
L
F
S
-
SS
DY
RATLAQ
fig|536056.3.peg.3921
Escherichia coli DH1 (2-206/210)
I
L
H
PS
L
A
SA
N
P
L
HY
G
R
E
L
T
A
LDNLD
FG
SL
H
L
D
I
E
D
S
SF
I
N
N
I
T
F
G
M
KT
V
QA
V
AR
QT
-
P
H
P
L
SF
H
F
M
L
A
RPQ
R
W
F
N
A
L
A
E
I
RP
AW
I
F
V
H
A
E
T
-
L
D
Y
P
S
E
TL
T
E
I
R
HT
G
A
R
AGLVFNPATP
I
D
A
WR
Y
L
AS
E
LD
G
VM
V
M
TS
E
P
D
G
Q
GQ
R
FIP
S
M
C
E
K
IQ
K
VR
TA
F
P
Q
T
-
-
--
E
CWA
DGG
I
T
L
A
A
AQ
Q
L
AAAGA
QH
M
V
I
G
-
R
A
L
F
S
-
SS
DY
RATLAQ
fig|656379.3.peg.96
Escherichia coli FVEC1302 (2-206/210)
I
L
H
PS
L
A
SA
N
P
L
HY
G
R
E
L
T
A
LDNLD
FG
SL
H
L
D
I
E
D
S
SF
I
N
N
I
T
F
G
M
KT
V
QA
V
AR
QT
-
P
H
P
L
SF
H
F
M
L
A
RPQ
R
W
F
N
A
L
A
E
I
RP
AW
I
F
V
H
A
E
T
-
L
D
Y
P
S
E
TL
T
E
I
R
HT
G
A
R
AGLVFNPATP
I
D
A
WR
Y
L
AS
E
LD
G
VM
V
M
TS
E
P
D
G
Q
GQ
R
FIP
S
M
C
E
K
IQ
K
VR
TA
F
P
Q
T
-
-
--
E
CWA
DGG
I
T
L
A
A
AQ
Q
L
AAAGA
QH
M
V
I
G
-
R
A
L
F
S
-
SS
DY
RATLAQ
fig|656380.3.peg.34
Escherichia coli FVEC1412 (2-206/210)
I
L
H
PS
L
A
SA
N
P
L
HY
G
R
E
L
T
A
LDNLD
FG
SL
H
L
D
I
E
D
S
SF
I
N
N
I
T
F
G
M
KT
V
QA
V
AR
QT
-
P
H
P
L
SF
H
F
M
L
A
RPQ
R
W
F
N
A
L
A
E
I
RP
AW
I
F
V
H
A
E
T
-
L
D
Y
P
S
E
TL
T
E
I
R
HT
G
A
R
AGLVFNPATP
I
D
A
WR
Y
L
AS
E
LD
G
VM
V
M
TS
E
P
D
G
Q
GQ
R
FIP
S
M
C
E
K
IQ
K
VR
TA
F
P
Q
T
-
-
--
E
CWA
DGG
I
T
L
A
A
AQ
Q
L
AAAGA
QH
M
V
I
G
-
R
A
L
F
S
-
SS
DY
RATLAQ
fig|83333.1.peg.4210
Escherichia coli K12 (2-206/210)
I
L
H
PS
L
A
SA
N
P
L
HY
G
R
E
L
T
A
LDNLD
FG
SL
H
L
D
I
E
D
S
SF
I
N
N
I
T
F
G
M
KT
V
QA
V
AR
QT
-
P
H
P
L
SF
H
F
M
L
A
RPQ
R
W
F
N
A
L
A
E
I
RP
AW
I
F
V
H
A
E
T
-
L
D
Y
P
S
E
TL
T
E
I
R
HT
G
A
R
AGLVFNPATP
I
D
A
WR
Y
L
AS
E
LD
G
VM
V
M
TS
E
P
D
G
Q
GQ
R
FIP
S
M
C
E
K
IQ
K
VR
TA
F
P
Q
T
-
-
--
E
CWA
DGG
I
T
L
A
A
AQ
Q
L
AAAGA
QH
M
V
I
G
-
R
A
L
F
S
-
SS
DY
RATLAQ
fig|656419.3.peg.28
Escherichia coli M718 (2-206/210)
I
L
H
PS
L
A
SA
N
P
L
HY
G
R
E
L
T
A
LDNLD
FG
SL
H
L
D
I
E
D
S
SF
I
N
N
I
T
F
G
M
KT
V
QA
V
AR
QT
-
P
H
P
L
SF
H
F
M
L
A
RPQ
R
W
F
N
A
L
A
E
I
RP
AW
I
F
V
H
A
E
T
-
L
D
Y
P
S
E
TL
T
E
I
R
HT
G
A
R
AGLVFNPATP
I
D
A
WR
Y
L
AS
E
LD
G
VM
V
M
TS
E
P
D
G
Q
GQ
R
FIP
S
M
C
E
K
IQ
K
VR
TA
F
P
Q
T
-
-
--
E
CWA
DGG
I
T
L
A
A
AQ
Q
L
AAAGA
QH
M
V
I
G
-
R
A
L
F
S
-
SS
DY
RATLAQ
fig|749540.3.peg.3001
Escherichia coli MS 146-1 (2-206/210)
I
L
H
PS
L
A
SA
N
P
L
HY
G
R
E
L
T
A
LDNLD
FG
SL
H
L
D
I
E
D
S
SF
I
N
N
I
T
F
G
M
KT
V
QA
V
AR
QT
-
P
H
P
L
SF
H
F
M
L
A
RPQ
R
W
F
N
A
L
A
E
I
RP
AW
I
F
V
H
A
E
T
-
L
D
Y
P
S
E
TL
T
E
I
R
HT
G
A
R
AGLVFNPATP
I
D
A
WR
Y
L
AS
E
LD
G
VM
V
M
TS
E
P
D
G
Q
GQ
R
FIP
S
M
C
E
K
IQ
K
VR
TA
F
P
Q
T
-
-
--
E
CWA
DGG
I
T
L
A
A
AQ
Q
L
AAAGA
QH
M
V
I
G
-
R
A
L
F
S
-
SS
DY
RATLAQ
fig|749548.3.peg.597
Escherichia coli MS 196-1 (2-206/210)
I
L
H
PS
L
A
SA
N
P
L
HY
G
R
E
L
T
A
LDNLD
FG
SL
H
L
D
I
E
D
S
SF
I
N
N
I
T
F
G
M
KT
V
QA
V
AR
QT
-
P
H
P
L
SF
H
F
M
L
A
RPQ
R
W
F
N
A
L
A
E
I
RP
AW
I
F
V
H
A
E
T
-
L
D
Y
P
S
E
TL
T
E
I
R
HT
G
A
R
AGLVFNPATP
I
D
A
WR
Y
L
AS
E
LD
G
VM
V
M
TS
E
P
D
G
Q
GQ
R
FIP
S
M
C
E
K
IQ
K
VR
TA
F
P
Q
T
-
-
--
E
CWA
DGG
I
T
L
A
A
AQ
Q
L
AAAGA
QH
M
V
I
G
-
R
A
L
F
S
-
SS
DY
RATLAQ
fig|749549.3.peg.4139
Escherichia coli MS 198-1 (2-206/210)
I
L
H
PS
L
A
SA
N
P
L
HY
G
R
E
L
T
A
LDNLD
FG
SL
H
L
D
I
E
D
S
SF
I
N
N
I
T
F
G
M
KT
V
QA
V
AR
QT
-
P
H
P
L
SF
H
F
M
L
A
RPQ
R
W
F
N
A
L
A
E
I
RP
AW
I
F
V
H
A
E
T
-
L
D
Y
P
S
E
TL
T
E
I
R
HT
G
A
R
AGLVFNPATP
I
D
A
WR
Y
L
AS
E
LD
G
VM
V
M
TS
E
P
D
G
Q
GQ
R
FIP
S
M
C
E
K
IQ
K
VR
TA
F
P
Q
T
-
-
--
E
CWA
DGG
I
T
L
A
A
AQ
Q
L
AAAGA
QH
M
V
I
G
-
R
A
L
F
S
-
SS
DY
RATLAQ
fig|637912.3.peg.3145
Escherichia coli OP50 (2-206/210)
I
L
H
PS
L
A
SA
N
P
L
HY
G
R
E
L
T
A
LDNLD
FG
SL
H
L
D
I
E
D
S
SF
I
N
N
I
T
F
G
M
KT
V
QA
V
AR
QT
-
P
H
P
L
SF
H
F
M
L
A
RPQ
R
W
F
N
A
L
A
E
I
RP
AW
I
F
V
H
A
E
T
-
L
D
Y
P
S
E
TL
T
E
I
R
HT
G
A
R
AGLVFNPATP
I
D
A
WR
Y
L
AS
E
LD
G
VM
V
M
TS
E
P
D
G
Q
GQ
R
FIP
S
M
C
E
K
IQ
K
VR
TA
F
P
Q
T
-
-
--
E
CWA
DGG
I
T
L
A
A
AQ
Q
L
AAAGA
QH
M
V
I
G
-
R
A
L
F
S
-
SS
DY
RATLAQ
fig|585035.6.peg.4814
Escherichia coli S88 (2-206/210)
I
L
H
PS
L
A
SA
N
P
L
HY
G
R
E
L
T
A
LDNLD
FG
SL
H
L
D
I
E
D
S
SF
I
N
N
I
T
F
G
M
KT
V
QA
V
AR
QT
-
P
H
P
L
SF
H
F
M
L
A
RPQ
R
W
F
N
A
L
A
E
I
RP
AW
I
F
V
H
A
E
T
-
L
D
Y
P
S
E
TL
T
E
I
R
HT
G
A
R
AGLVFNPATP
I
D
A
WR
Y
L
AS
E
LD
G
VM
V
M
TS
E
P
D
G
Q
GQ
R
FIP
S
M
C
E
K
IQ
K
VR
TA
F
P
Q
T
-
-
--
E
CWA
DGG
I
T
L
A
A
AQ
Q
L
AAAGA
QH
M
V
I
G
-
R
A
L
F
S
-
SS
DY
RATLAQ
fig|585056.7.peg.5065
Escherichia coli UMN026 (2-206/210)
I
L
H
PS
L
A
SA
N
P
L
HY
G
R
E
L
T
A
LDNLD
FG
SL
H
L
D
I
E
D
S
SF
I
N
N
I
T
F
G
M
KT
V
QA
V
AR
QT
-
P
H
P
L
SF
H
F
M
L
A
RPQ
R
W
F
N
A
L
A
E
I
RP
AW
I
F
V
H
A
E
T
-
L
D
Y
P
S
E
TL
T
E
I
R
HT
G
A
R
AGLVFNPATP
I
D
A
WR
Y
L
AS
E
LD
G
VM
V
M
TS
E
P
D
G
Q
GQ
R
FIP
S
M
C
E
K
IQ
K
VR
TA
F
P
Q
T
-
-
--
E
CWA
DGG
I
T
L
A
A
AQ
Q
L
AAAGA
QH
M
V
I
G
-
R
A
L
F
S
-
SS
DY
RATLAQ
fig|316407.3.peg.4127
Escherichia coli W3110 (2-206/210)
I
L
H
PS
L
A
SA
N
P
L
HY
G
R
E
L
T
A
LDNLD
FG
SL
H
L
D
I
E
D
S
SF
I
N
N
I
T
F
G
M
KT
V
QA
V
AR
QT
-
P
H
P
L
SF
H
F
M
L
A
RPQ
R
W
F
N
A
L
A
E
I
RP
AW
I
F
V
H
A
E
T
-
L
D
Y
P
S
E
TL
T
E
I
R
HT
G
A
R
AGLVFNPATP
I
D
A
WR
Y
L
AS
E
LD
G
VM
V
M
TS
E
P
D
G
Q
GQ
R
FIP
S
M
C
E
K
IQ
K
VR
TA
F
P
Q
T
-
-
--
E
CWA
DGG
I
T
L
A
A
AQ
Q
L
AAAGA
QH
M
V
I
G
-
R
A
L
F
S
-
SS
DY
RATLAQ
fig|316385.7.peg.4546
Escherichia coli str. K-12 substr. DH10B (2-206/210)
I
L
H
PS
L
A
SA
N
P
L
HY
G
R
E
L
T
A
LDNLD
FG
SL
H
L
D
I
E
D
S
SF
I
N
N
I
T
F
G
M
KT
V
QA
V
AR
QT
-
P
H
P
L
SF
H
F
M
L
A
RPQ
R
W
F
N
A
L
A
E
I
RP
AW
I
F
V
H
A
E
T
-
L
D
Y
P
S
E
TL
T
E
I
R
HT
G
A
R
AGLVFNPATP
I
D
A
WR
Y
L
AS
E
LD
G
VM
V
M
TS
E
P
D
G
Q
GQ
R
FIP
S
M
C
E
K
IQ
K
VR
TA
F
P
Q
T
-
-
--
E
CWA
DGG
I
T
L
A
A
AQ
Q
L
AAAGA
QH
M
V
I
G
-
R
A
L
F
S
-
SS
DY
RATLAQ
fig|511145.12.peg.4437
Escherichia coli str. K-12 substr. MG1655 (2-206/210)
I
L
H
PS
L
A
SA
N
P
L
HY
G
R
E
L
T
A
LDNLD
FG
SL
H
L
D
I
E
D
S
SF
I
N
N
I
T
F
G
M
KT
V
QA
V
AR
QT
-
P
H
P
L
SF
H
F
M
L
A
RPQ
R
W
F
N
A
L
A
E
I
RP
AW
I
F
V
H
A
E
T
-
L
D
Y
P
S
E
TL
T
E
I
R
HT
G
A
R
AGLVFNPATP
I
D
A
WR
Y
L
AS
E
LD
G
VM
V
M
TS
E
P
D
G
Q
GQ
R
FIP
S
M
C
E
K
IQ
K
VR
TA
F
P
Q
T
-
-
--
E
CWA
DGG
I
T
L
A
A
AQ
Q
L
AAAGA
QH
M
V
I
G
-
R
A
L
F
S
-
SS
DY
RATLAQ
fig|511145.6.peg.4416
Escherichia coli str. K-12 substr. MG1655 (2-206/210)
I
L
H
PS
L
A
SA
N
P
L
HY
G
R
E
L
T
A
LDNLD
FG
SL
H
L
D
I
E
D
S
SF
I
N
N
I
T
F
G
M
KT
V
QA
V
AR
QT
-
P
H
P
L
SF
H
F
M
L
A
RPQ
R
W
F
N
A
L
A
E
I
RP
AW
I
F
V
H
A
E
T
-
L
D
Y
P
S
E
TL
T
E
I
R
HT
G
A
R
AGLVFNPATP
I
D
A
WR
Y
L
AS
E
LD
G
VM
V
M
TS
E
P
D
G
Q
GQ
R
FIP
S
M
C
E
K
IQ
K
VR
TA
F
P
Q
T
-
-
--
E
CWA
DGG
I
T
L
A
A
AQ
Q
L
AAAGA
QH
M
V
I
G
-
R
A
L
F
S
-
SS
DY
RATLAQ
Consen1
Primary consensus
MKQYlI
PSi
saD
arlgedt
k
ad
H
DvMDnhyVpNlT
gP
l
lrn
it
PiDvHlMv
pvdr
v
dfA
aGA
It
HpEa
-
s
hv
rtlqlIk
g
KaGLvfNPaTPl
yldY
mdklD
IllMsvnPGf
GQ
FIPqtLdKlrevr
i
e
g
dirlEVDGgvk
nn
eiaAAGADmfvaG
-
saiFd
-
qpDYkkvideMRSELAKVSHE
Consen2
Secondary consensus
i
l
cm
lkfkr
i
f
fg
i
gsf
n
i
s
v
vkk
-
s
l
c
f
l
rpqd
i
ql
i
f
a
ti
qa
elide
r
d
v
il
e
a
hea
tv
tsd
g
m
e
aklk
r
-
eyei
scn
at
lm
miv
trgl
nhae
ratlaq
Consensus 1
(when a gap)
Conservative difference
Consensus 2
(when a gap)
Nonconservative diff.
Other character