┌─ Escherichia coli ED1a (5)  
                             ┌─────────────────┴────────────────── Escherichia coli (15-469/469) E2348/69 (1)  
                            ┌┴────────────────── Escherichia coli MS 200-1   
                           ┌┴─ Escherichia coli (15-469/469) APEC O1 (16)  
┌──────────────────────────┴────────────────── Escherichia coli 536 (1)  
┤                          ┌────────────────── Escherichia coli H736   
└──────────────────────────┤┌────────────────── Escherichia coli E22 (1)  
                           └┤┌─ Escherichia coli K12 (66)  
                            └┤                  ┌─ Escherichia coli 1044A (19)  
                             └┬─────────────────┴─ Escherichia coli O157:H7 EDL933   
                              └─────────────────┬────────────────── Escherichia coli IAI39 (1)  
                                                └┬────────────────── Escherichia coli H299   
                                                 └─ Escherichia coli MS 21-1 (2)  
  

  
Outer membrane stress sensor protease DegQ, serine protease
 (13)