┌─────────────────────── Escherichia coli B171 (1)  
┤    ┌───────────────────────────── Escherichia coli EC4100B   
└────┤        ┌───────────────────────────── Escherichia coli BW2952 (2)  
     │     ┌──┴─── Escherichia coli K12 (97)  
     └──┬──┴───────────────────────────── Escherichia coli B str. REL606 (3)  
        └────────────────────────────┬─── Escherichia coli 536 (21)  
                                     └──┬───────────────────────────── Escherichia coli 83972 (1)  
                                        └───────────────────────────── Escherichia coli ED1a (1)  
  

  
GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)
 (8)