┌──────────────────────────────────────────────────────────────────── Escherichia coli (3-423/432) O157:H7 str. EC4024   
┤                                                                   ┌─ Escherichia coli O157:H7 EDL933 (1)  
└───────────────────────────────────────────────────────────────────┤ ┌─ Escherichia coli 101-1 (5)  
                                                                    │┌┴─ Escherichia coli M718   
                                                                    └┤┌─ Escherichia coli WV_060327   
                                                                     └┤ ┌─ Escherichia coli 53638 (1)  
                                                                      └┬┴─ Escherichia coli K12 (109)  
                                                                       └┬─ Escherichia coli MS 115-1   
                                                                        └┬─ Escherichia coli MS 198-1   
                                                                         └─ Escherichia coli 042 (4)  
  

  
Copper sensory histidine kinase CpxA
 (9)
  
Sensory histidine kinase in two-component regulatory system with RstA
 (1)