┌─ Escherichia coli TA280   
               ┌───────────────┴───────────────── Escherichia coli MS 69-1   
       ┌───────┴─ Escherichia coli B354   
┌──────┴────────────────┬─ Escherichia coli FVEC1302 (3)  
│                       └──────── Escherichia coli TA143   
│                                                          ┌─ Escherichia coli IAI39 (1)  
┤                        ┌─────────────────────────────────┴──────── Escherichia coli MS 21-1   
│                ┌───────┴───────────────── Escherichia coli SMS-3-5   
│        ┌───────┴──────── Escherichia coli H299   
│        │┌──────── Escherichia coli NC101   
└────────┤│                    ┌──────── Escherichia coli (2-212/212) E2348/69   
         ││                   ┌┴──────── Escherichia coli (2-212/212) CFT073 (5)  
         ││                  ┌┴─ Escherichia coli 2362-75   
         └┤          ┌───────┴───────┬──────── Escherichia coli M605   
          │         ┌┤               └─ Escherichia coli SE15   
          │        ┌┤└─ Escherichia coli (2-212/212) APEC O1 (9)  
          │┌───────┤└──────── Escherichia coli 536 (6)  
          └┤       └────────────────────────────────── Escherichia coli (2-212/212) 042 (1)  
           │       ┌──────── Escherichia coli HS (4)  
           └───────┤┌─ Escherichia coli B171 (21)  
                   └┤        ┌─ Escherichia coli 1044A (22)  
                    │┌───────┴─ Escherichia coli O157:H7 EDL933 (1)  
                    └┤        ┌─ Escherichia coli K12 (27)  
                     │       ┌┴──────────────── Escherichia coli ETEC H10407   
                     └───────┤ ┌──────── Escherichia coli H591 (1)  
                             └┬┴──────── Escherichia coli DH1   
                              └┬───────── Escherichia coli str. K-12 substr. DH10B   
                               └─┬────────────────── Escherichia coli B088   
                                 └────── Escherichia coli 53638 (1)  
  

  
Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)
 (29)